Clinical trials: Concentration
Attention Deficit Disorder With Hyperactivity
Preventing Behavior Problems in Children With ADHD
This study will determine the effectiveness of a combination of treatments in preventing behaviors that are typically associated with Attention Deficit Hyperactivity Disorder (ADHD) in young children.
- Trial name
- NCT00057668
- Testing
- Multi-Setting Early Intervention, Community Intervention
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lehigh University
Attention Deficit Hyperactivity Disorder
Study on the Quality of Life Among Adolescents With Attention Deficit/Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder (ADHD) with a overall prevalence of 5.3% is one of the most common neurobehavioral disorders in children.
- Trial name
- QuaVAT (NCT03719950)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Psychothérapique de Nancy
Attention Deficit Hyperactivity Disorders, Neurodevelopmental Disorders
Good Night Project: Behavioural Sleep Interventions for Children With ADHD: A Randomised Controlled Trial
The study aims to implement and evaluate an RCT of behavioural sleep interventions for children aged 5-12 years with ADHD, and their primary caregivers, (women) in Saudi Arabia to address the following questions: 1.
- Conditions
- Attention Deficit Hyperactivity Disorders, Neurodevelopmental Disorders, Attention Deficit Disorder With Hyperactivity
- Trial name
- NCT02871674
- Testing
- Good Night Project
- Volunteers
- 60 people
- Sponsor
- University of Leeds
Obsessive Compulsive Disorder
Attention Training for Childhood Obsessive Compulsive Disorder
Voluntary and involuntary attention processes are thought to play an important role in the development and maintenance of anxiety disorders including OCD.
- Trial name
- AMP-OCD (NCT02114918)
- Testing
- Attention Modification Program, Attention Control Condition
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of California, Los Angeles
Healthy Male and Female Subjects
The Effect of Cycling, Running, and Playing Rugby on Three Biomarkers That May Indicate Brain Injury
The goal of this clinical trial was to determine if and how the biomarkers neurofilament light (NfL), brain lipid binding protein (BLBP), and amyloid precursor protein (APP) accumulated over 72 hours in venous blood following…
- Trial name
- NCT06804291
- Testing
- Running, Cycling, Rugby
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Rheumatoid Arthritis, Healthy Volunteers
Effects of Administration of Fostamatinib on Blood Concentrations of Rifampicin in Healthy Subjects.
The purpose of this study is to investigate the drug interaction between fostamatinib and rifampicin by comparing the safety, tolerability and plasma concentration of fostamatinib when administered alone and with rifampicin in…
- Trial name
- NCT01336218
- Testing
- fostamatinib, rifampicin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Change in Fasting Plasma LDL-cholesterol Concentration After the Consumption of Quinoa
Effects of Quinoa Consumption on Markers of Cardiovascular Risk and Gastrointestinal Health
Quinoa is possible alternative to wheat, corn and rice due to its high nutritional value and possible properties against cardiovascular diseases and for improving gut health.
- Trial name
- NCT03036618
- Testing
- Quinoa, Wheat
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Diffusive and Convective Clearance, Body Clearance
Pharmacokinetics of Piperacillin/Tazobactam in Patients Treated by Continuous Renal Replacement Therapy
The pharmacokinetics of piperacillin/tazobactam will be evaluated in twenty septic patients with renal failure undergoing continuous veno-venous hemodiafiltration.
- Conditions
- Diffusive and Convective Clearance, Body Clearance, Piperacillin Tazocilline Concentrations (Cmin)
- Trial name
- PTCRRT (NCT00703144)
- Testing
- piperacillin/tazobactam, Pharmacokinetic
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Toulouse
Neovascular Age-related Macular Degeneration
Safety and Efficacy of AM712 in Patients with NAMD
The purpose of this Phase 1 study is comprised of multiple ascending-dose component (Part 1) and high concentration component (Part 2) to evaluate the safety, tolerability, pharmacokinetics, and efficacy of AM712 in patients with…
- Trial name
- NCT05345769
- Testing
- AM712(ASKG712)
- Where
- 9 sites in United States
- Volunteers
- 21 people
- Sponsor
- AffaMed Therapeutics Limited
Flumazenil to Antagonize Remimazolam, Remimazolam
Flumazenil Antagonism of Remimazolam in Kidney Transplant Patients
To investigate the effect of different doses of flumazenil antagonism on remimazolam plasma concentration in patients undergoing renal transplantation under general anesthesia.
- Conditions
- Flumazenil to Antagonize Remimazolam, Remimazolam, Renal Transplantation
- Trial name
- NCT06531369
- Testing
- Flumazenil Injection（F1 group）, Flumazenil Injection（F2 group）, Saline（C group）
- Volunteers
- 60 people
- Sponsor
- Qianfoshan Hospital
Mineral-bone Metabolism
The Effects of Different Dialysate Calcium Concentration
The investigators enrolled 90 patients on maintenance hemodialysis with dialytic vintage ≥12 months, iPTH 150-300pg/ml and serum calcium<2.5mmol/L.
- Trial name
- NCT01839383
- Testing
- different dialysate calcium concentration
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Beijing Friendship Hospital
ADHD NOS
Strattera Treatment in Adults With Attention Deficit Hyperactivity Disorder Not Otherwise Specified (ADHD NOS)
This is an open-label study with daily doses up to 144 mg/day Strattera (atomoxetine) in the treatment of adults with attention deficit hyperactivity disorder not otherwise specified.
- Trial name
- NCT00181766
- Testing
- Strattera (atomoxetine)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Massachusetts General Hospital
Catheter-Related Infections, Bacteremia.
Concentration of Antimicrobials in Catheter-lock Solutions
The antibiotic lock technique (ALT) is used as local treatment for Catheter-Related Bacteremia (CRB). It consists in the administration of a concentrated antimicrobial solution with a calculated volume to fill the lumen of the…
- Trial name
- CONAN (NCT01592032)
- Testing
- Vancomycin antimicrobial-lock solution, Teicoplanin antimicrobial-lock solution, Linezolid antimicrobial-lock solution
- Where
- Spain
- Volunteers
- 125 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Angiogenesis, Colon Cancer
Postoperative VEGF and Recurrence After Colon Cancer Surgery
The purpose of this trial is to study the relationship between the angiogenic response to surgical aggression, determined through the serum levels of vascular endothelial growth factor (VEGF) on postoperative day four, and the…
- Conditions
- Angiogenesis, Colon Cancer, Surgery, Recurrence
- Trial name
- NCT04851054
- Testing
- Surgery for colon cancer with intention to cure
- Volunteers
- 280 people
- Sponsor
- Hospital del Mar
Rheumatoid Arthritis, Healthy Volunteers
Effects of Administration of Fostamatinib on Blood Concentrations of Pioglitazone in Healthy Subjects
The purpose of this study is to investigate the drug interaction between fostamatinib and pioglitazone by comparing the safety, tolerability and plasma concentration of pioglitazone when administered alone and with fostamatinib…
- Conditions
- Rheumatoid Arthritis, Healthy Volunteers, Pharmacokinetics, Pioglitazone
- Trial name
- NCT01309854
- Testing
- fostamatinib, pioglitazone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Maximum Observed Plasma Glucose Concentration (Cmax)
Processed Orange and the Glycemic Response
Randomized, placebo controlled, double blind, postprandial crossover study in male subjects. 3 intervention arms, consisting of a control (Product A), a low dose processed whole orange (Product B) and a high dose processed whole…
- Trial name
- POGR (NCT02112851)
- Testing
- Orange flavored beverage
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Pneumococcal Disease
Study to Evaluate Safety, Reactogenicity and Immunogenicity of the Pneumococcal Protein PhtD Vaccine in Healthy Adults
The purpose of this study is to examine the safety, reactogenicity and immunogenicity of the GlaxoSmithKline (GSK) Biologicals candidate pneumococcal vaccine containing PhtD in healthy elderly population aged 18-45 years of age.
- Trial name
- NCT01767402
- Testing
- PhtD vaccine with/without adjuvant, Pneumovax 23TM, NaCl
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sleep Bruxism, Adolescent
Effectiveness of Melissa Officinalis for the Treatment of Probable Sleep Bruxism in Children and Adolescents
Objective: To investigate, through a controlled and randomized clinical trial, the effectiveness of using Melissa officinalis in different concentrations in the treatment of children and adolescents with probable sleep bruxism.
- Conditions
- Sleep Bruxism, Adolescent, Children, Temporomandibular Joint Disorders
- Trial name
- NCT06214637
- Testing
- Melissa
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Irreversible Pulpitis, Extremely Deep Caries
Outcome Following Use of Different Concentrations of NaOCl as Wound Lavage and Hemostatic Agent in Partial Pulpotomy
The aim of this randomised control trial is to compare the effect of different concentrations of NaOCl on outcome of partial pulpotomy in teeth with clinical signs indicative of irreversible pulpitis.
- Conditions
- Irreversible Pulpitis, Extremely Deep Caries, Partial Pulpotomy
- Trial name
- NCT06433245
- Testing
- effect of 3% and 5% sodium hypochlorite on outcome of partial pulpotomy in teeth with clinical signs indicative of irreversible pulpitis.
- Where
- India
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Transgender Persons
Effect of Progesterone on Testosterone Concentrations and Breast Development in Transwomen
Purpose. The purpose of this research is study the effect of progesterone therapy on testosterone levels in transwomen who are currently on gender affirming treatment with estradiol. Duration.
- Trial name
- NCT04534881
- Testing
- Progesterone 200 MG
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- St. Louis University
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