Clinical trials: Concentration
Kidney Transplantation
Study Comparing Standard Dose and Reduced Dose Tacrolimus + Sirolimus + Corticosteroids in Renal Allograft Recipients
This study evaluated renal graft function based on calculated creatinine clearance at 6 months after transplantation in patients receiving a regimen of 'reduced' or 'standard' dose tacrolimus plus sirolimus and corticosteroids.
- Trial name
- NCT00518271
- Testing
- Rapamune® (Sirolimus), Tacrolimus, Corticosteroids
- Volunteers
- 120 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Attention Deficit Hyperactivity Disorder
Effects of Cognitive Training on Children With Attention Deficit Hyperactivity Disorder
Using a single blind, randomized controlled design to study the additional therapeutic effects of cognitive training on traditional rehabilitation programs for children with attention deficit hyperactivity disorder and…
- Trial name
- NCT03632629
- Testing
- interactive cognitive training
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Stroke Sequelae
Mantra Meditation in Subjects That Have Chronically Impaired Attention After Stroke
There is an evidence gap on whether meditation may improve behaviorally measured attention after stroke, but preliminary research is promising.
- Trial name
- NCT03229902
- Testing
- mantra meditation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Cheryl Carrico
Transplantation, Kidney Transplantation
Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets
The purpose of this study is to understand the pharmacokinetics of sirolimus tablets in different regimens in newly renal transplant patients, and the effect of dosage form conversion on the concentration of sirolimus in stable…
- Conditions
- Transplantation, Kidney Transplantation, Immunosuppression
- Trial name
- NCT00166842
- Testing
- sirolimus, cyclosporine, tacrolimus
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Attention Deficit Disorder With Hyperactivity
Leveraging Mobile Health Technology to Optimize Early Stimulant Medication Treatment: A Feasibility Pilot
The goal of this study is to develop and test a mobile web application to optimize early stimulant medication treatment for children receiving care for Attention/Deficit Hyperactivity Disorder (ADHD) in a publicly-funded mental…
- Trial name
- NCT01990222
- Where
- 3 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of California, Los Angeles
ADHD
Neurobiological Basis of Response to Vyvanse in Adults With ADHD: an fMRI Study of Brain Activation
The purpose of this study is to determine the effects of Vyvanse, an FDA approved medication used in the treatment of Attention Deficit Hyperactivity Disorder (ADHD), on brain activity in adults with attention-deficit…
- Trial name
- NCT01924429
- Testing
- Lisdexamfetamine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Jeffrey Newcorn
Healthy
A Study to Assess Nipocalimab Concentrations in Breast Milk of Healthy Lactating Women
The main purpose of this study is to assess the concentrations of nipocalimab (pharmacokinetics [PK]) in the breast milk after administration of a single dose of nipocalimab into the vein, in healthy lactating women.
- Trial name
- NCT07669077
- Testing
- Nipocalimab, Breast Milk Sampling
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
HIV Infections
Therapeutic HIV Vaccine and Interleukin-2 to Increase the Immune System's Response to HIV
This study will evaluate whether the HIV vaccine ALVAC vCP1452 given in combination with interleukin-2 (IL-2), also known as aldesleukin, can increase immune system function in people with HIV infection.
- Trial name
- NCT00056797
- Testing
- ALVAC HIV vaccine (vCP1452), Interleukin-2
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Encephalopathies, HIV Infections
A Study of Azidothymidine in HIV-Infected Children
AMENDED 07/07/93: To evaluate whether continuous infusion AZT will impact neurodevelopmental deficits associated with HIV infection or alter rate of encephalopathy progression in children who have failed to improve or shown…
- Trial name
- NCT00000982
- Testing
- Zidovudine, Didanosine
- Where
- 7 sites in United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pulmonary Atelectasis
Ventilation Strategy Reduces Postoperative Atelectasis
Atelectasis is common during and after general anesthesia. The investigators hypothesized that a ventilation strategy with a combination of 1) continuous positive airway pressure (CPAP) or positive end-expiratory pressure (PEEP)…
- Trial name
- NCT01911923
- Testing
- No CPAP/PEEP and 100 % oxygen, CPAP/PEEP and 30 % oxygen
- Where
- Sweden
- Sponsor
- Region Västmanland
Attention
Exploratory Randomized, Controlled, Dose-response Study on the Impact of Nicotine From Five Variants of a Nicotine Tablet (NICOTINE TABLET) on Attention
This study aims to provide initial insights into the impact of orally delivered nicotine on attentional performance in adult occasional users of nicotine pouches.
- Trial name
- NCT07408180
- Testing
- NICOTINE TABLET-0mg, NICOTINE TABLET-0.5mg, NICOTINE TABLET-1.0mg
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
ADHD, Hyperactivity
Treatment With Cannabis Oil Containing CBD, THC, CBDV or CBG vs. Placebo of Persons With ADHD
ADHD is the most frequent neuro-developmental disorder in childhood and often continues into adolescence and adulthood. Indicated drug treatments for ADHD fall into 2 categories: stimulants (such as methylphenidate and…
- Conditions
- ADHD, Hyperactivity, Attention Deficit
- Trial name
- NCT05219370
- Testing
- Cannabis oil
- Where
- Israel
- Volunteers
- 8 people
- Sponsor
- Brlev Agricultural Crops Ltd
Social Phobia
Cognitive Biases Modification Treatment for Social Anxiety
Adults with Social Phobia will be randomly assigned to either an attention bias modification treatment, interpretation bias modification treatment, both, or a placebo control condition not designed to change cognitive bias…
- Trial name
- CBMSP (NCT01503151)
- Testing
- Attention Bias Modification Treatment (ABMT), Interpretation Bias Modification (IBM), Control Condition
- Where
- Israel
- Volunteers
- 95 people
- Sponsor
- Tel Aviv University
Attention-deficit Hyperactivity Disorder
Online Mindfulness-Based Intervention for ADHD
This study aims to evaluate the efficacies of an online mindfulness-based intervention for emerging adults with ADHD in Malaysia.
- Trial name
- iMBI (NCT04229251)
- Testing
- Online Mindfulness-based Intervention, Online Introductory Psychology Program
- Where
- Malaysia
- Volunteers
- 108 people
- Sponsor
- Universiti Tunku Abdul Rahman
Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction
Optimizing Research With Diverse Families - Feasibility and Acceptability Study (FAST)
Evaluate feasibility and acceptability of recruiting Black and Hispanic families for an open label clinical trial of multinutrients while collecting real-time parent-reported child behavior data and collecting at-home…
- Conditions
- Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction, Irritable Mood
- Trial name
- FAST (NCT06133231)
- Testing
- Multinutrients; a 36-ingredient blend of vitamins, minerals, amino acids, and antioxidants
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oregon Health and Science University
Fertility Issues, Blastocyst IVF
A Multicenter Prospective Randomized Controlled Clinical Trial Comparing Constant (5%) Versus Sequential (5%-2%) Oxygen Concentration Embryo Culture Protocols in Assisted Reproductive Technology
To evaluate whether there were significant differences in the effects of constant (5%) versus sequential (5%-2%) oxygen concentration protocols in embryo culture on term live birth rates.
- Conditions
- Fertility Issues, Blastocyst IVF, Embryo Culture
- Trial name
- NCT07050537
- Testing
- Constant oxygen concentration protocols in embryo culture, Sequential oxygen concentration protocols in embryo culture
- Where
- 6 sites in China
- Volunteers
- 980 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Cardiac Surgery With Cardiopulmonary Bypass
Evaluation of Plasma Renin Concentrations in Cardiac Surgery
The purpose of this research is to learn more about how renin (a blood test) is affected by cardiopulmonary bypass, the heart-lung machine used during open heart surgery.
- Trial name
- NCT06895213
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Major Depressive Disorder
Mechanisms of Emotion Regulation Underlying Successful CBT in Depression
This research aims to elucidate mechanisms through which change occurs during cognitive behavior therapy (CBT) for depression. Assessing meta-cognitive processes of self-knowledge (top-down), electrophysiological and behavioral…
- Trial name
- NCT04328103
- Testing
- Cognitive Behavior Therapy (CBT), Nonspecific Supportive Therapy (PBO)
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- New York State Psychiatric Institute
Attention Deficit/Hyperactivity Disorder(ADHD), Alcohol Use
Smartphone-based Intervention for Young Adults With ADHD
The primary goal of this clinical trial is to test if a smartphone-based intervention is feasible \& acceptable among young adults with ADHD who also engage in risky drinking behaviors.
- Trial name
- NCT07654205
- Testing
- Ecological Momentary Assessment for ADHD and Substance Use - Intervention Group, Ecological Momentary Assessment for ADHD & Substance Use - Control Group
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Traci Kennedy
Elevated Blood Lipids
Effect of Plant Stanol Esters on Blood Lipids
This study aims to measure the effect of plant stanol esters on serum total and lipoproteins lipids, non-cholesterol sterols and apolipoproteins in subjects with elevated fasting blood lipid concentrations
- Trial name
- NCT00920894
- Testing
- plant stanol ester
- Where
- Finland
- Volunteers
- 112 people
- Sponsor
- Clinical Life Sciences Ltd.
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