Clinical trials: Concept Formation
COVID-19
Targeting de Novo Pyrimidine Biosynthesis by Leflunomide for the Treatment of COVID-19 Virus Disease
The global COVID-19 pandemic has caused unprecedented strain on health care services around the world.The absence of specific anti-viral medications to treat the underlying infection led to a proliferation of clinical studies and…
- Trial name
- DEFEAT-COVID (NCT05007678)
- Testing
- leflunomide
- Where
- United Kingdom
- Volunteers
- 178 people
- Sponsor
- Ashford and St. Peter's Hospitals NHS Trust
Chronic Pain
Turkish Version of The Conceptualization of Pain Questionnaire
The Conceptualization of Pain Questionnaire (COPAQ), has been presented to the literature in order to evaluate the concept of pain in children and its psychometric properties.
- Trial name
- NCT05436353
- Testing
- Turkish validity and reliability
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Kutahya Health Sciences University
Chronic Kidney Disease
Uraemic Toxins in Chronic Kidney Disease Paediatric Patients: Observational Study
Children with chronic kidney disease (CKD) suffer from one of the most devastating diseases in childhood resulting in a lifelong need for health care, and a 3 times decreased life expectancy.
- Trial name
- UToPaed_1 (NCT02624466)
- Testing
- CKD progress
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- University Hospital, Ghent
Surgical Adhesions
Study of PXL01 Versus Placebo to Inhibit Adhesion Formation After Flexor Tendon Surgery
The objectives of the study are to assess efficacy, safety, and handling of PXL01 in patients with flexor tendon injury in zone I or II.
- Trial name
- PHSU02 (NCT01022242)
- Testing
- PXL01
- Where
- 15 sites in Denmark, Germany and 1 more
- Volunteers
- 138 people
- Sponsor
- Pergamum AB
Bariatric Surgery, Hypoglycemia
Assessing Insulin Turnover Using an In-vivo Deuterated Water Experiment.
The primary objective of this study is to observe the kinetics of pre-stored and de-novo synthesized insulin that is secreted into the circulation using an in-vivo heavy water (D2O) labelling experiment in patients with…
- Conditions
- Bariatric Surgery, Hypoglycemia, Gastric Bypass
- Trial name
- DEEP1A (NCT04332289)
- Testing
- Heavy water experiment
- Where
- Switzerland
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Lia Bally
Students, Nursing, Education, Nursing
The Effect of Puzzles on Concept Learning in Nursing Students
Vital signs are concepts that first-year nursing students learn for the first time. Students are afraid of making mistakes in the concepts they are trying to learn for the first time.
- Trial name
- NCT06170567
- Testing
- The effect of puzzles on students' course success
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi
Knee Arthritis Osteoarthritis
Comparing Pain Science Education to Biomedical Education for People With Knee Osteoarthritis: A Randomized Controlled Trial
Knee osteoarthritis (OA) is a common cause of pain and disability in older adults. Many people with knee OA believe that pain is primarily caused by joint damage or "wear and tear." These beliefs may contribute to fear of…
- Trial name
- NCT07823673
- Testing
- Pain Science Education, Biomedical Education
- Volunteers
- 82 people
- Sponsor
- McMaster University
Cataract
A Study To Assess A Novel Form Of Cataract Treatment Using The Non-Invasive REVISYON Proof-Of-Concept Device
Single arm proof-of-concept trial to evaluate the safety and efficacy of the REVISYON PoC Device in the treatment of cataract.
- Trial name
- NCT04569318
- Testing
- Treatment Beam
- Where
- Latvia
- Volunteers
- 11 people
- Sponsor
- Edinburgh Biosciences Ltd
Surgical Scar
SCARFREE-001: Verteporfin for Scar Prevention
The purpose of this clinical trial is to investigate whether the drug verteporfin can reduce the formation of scars in adult patients undergoing a tummy tuck procedure (abdominoplasty).
- Trial name
- SCARFREE-001 (NCT07488988)
- Testing
- Verteporfin Injection, Saline injection
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Odense University Hospital
Personality Disorder
An Evolutionarily Informed Conceptualization of Personality Pathology
The purpose of this study is to explore the reliability of a new evolutionarily-informed model for conceptualizing personality pathology.
- Trial name
- EIC-PP (NCT06623838)
- Testing
- Evolutionarily informed case conceptualization
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tages Onlus
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts"
The investigators are examining whether difficulties with cognitive control (i.e., the ability to stop one's thought process and shift attention) is a common problem across three types of repetitive, negative thinking: obsessions…
- Conditions
- Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
- Trial name
- NCT03414619
- Testing
- Cognitive Control Tasks and Script Driven Imagery
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Eating Disorders, Eating Disorder Binge
Conceptualisation of a Network Approach to Complete the Classification of Eating Disorders With the Aim of Better Personalising Their Management
Eating disorders (EDBs) are mental disorders with a great impact on the lives of individuals as well as a great cost imposed on society.
- Trial name
- CASCADE (NCT06252688)
- Testing
- Ambulatory cares in a day-hospital (Lapeyronie, Montpellier) specialized in the evaluation of eating disorders.
- Volunteers
- 840 people
- Sponsor
- University Hospital, Montpellier
Arterial Blood Gas Analysis Education
Concept Mapping and Gamification in Arterial Blood Gas Analysis Education
Arterial blood gas (ABG) analysis is a complex clinical competency that requires the integrated interpretation of acid-base balance, oxygenation, and ventilation parameters in relation to the clinical presentation.
- Trial name
- NCT07611851
- Testing
- Concept Mapping, Traditional Education, Gamification-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cemile Nida Kayış
Healthy Adults
Effect of Water Intake on the DNA Adducts Formation
The main purpose of the study is to assess the effect of water intake on the formation of 4-ABP DNA adducts.
- Trial name
- NCT01583387
- Testing
- 1-Increased water intake regimen, 2-Non-modified water intake regimen
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Child Development, Pain
Validation of the Spanish Version of the Conceptualization of Pain Questionnaire
The goal of this observational study is to develop a questionnaire to assess a child's concept of pain and to evaluate its psychometric properties in schoolchildren aged 8-17 years.
- Conditions
- Child Development, Pain, Adolescent Behavior
- Trial name
- COPAQ-S (NCT06114927)
- Testing
- Validation of a questionnaire
- Where
- Spain
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Emotional Distress, Anxiety
Conceptualization and Scale Development of Excessive Emotional Behaviors
Emotional disorders, including anxiety and depression, represent a major global health burden and are increasingly conceptualized within a transdiagnostic framework.
- Conditions
- Emotional Distress, Anxiety, Depression Anxiety Disorder
- Trial name
- NCT07558772
- Where
- China
- Volunteers
- 637 people, healthy volunteers welcome
- Sponsor
- Xinghua Liu
Scar Formation
Effect of YAP1-inhibition in Surgical Wounds.
When we get injured, our body naturally tries to heal. In adults, this healing often leads to scars - thick, stiff tissue known as fibrotic tissue.
- Trial name
- NCT06944249
- Testing
- Verteporfin Injection
- Volunteers
- 24 people
- Sponsor
- Jöri Pünchera
Chronic Kidney Disease
Uraemic Toxins in Chronic Kidney Disease Paediatric Patients: Interventional Study
Children with chronic kidney disease (CKD) suffer from one of the most devastating diseases in childhood resulting in a lifelong need for health care, and a 3 times decreased life expectancy.
- Trial name
- UToPaed_3 (NCT02634775)
- Testing
- Change in treatment strategy
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Hospital, Ghent
Error Disclosure
DECIDE Just Culture: Conceptualization of Clinical Error
The main objective of this project is to extend the principles of Just Culture in primary care, hospitals and social-health centers, providing new information on key elements in the social and professional conceptualization of…
- Trial name
- DECIDE (NCT06835517)
- Testing
- Theory of Dissonance, Theory of Reasoned Action
- Where
- Spain
- Volunteers
- 1,255 people, healthy volunteers welcome
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Abstract Thinking, Concept Formation
Prefrontal Cortex and Abstract Thinking
The capacity of concept formation is not well understood, even if a link is supposed with the functioning of the frontal lobes. Our aim is to better understand the cognitive mechanisms underlying this function and to try to…
- Trial name
- NCT01100281
- Testing
- Neuropsychological examination, MRI
- Where
- France
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France