Clinical trials: Conception
PCOS (Polycystic Ovary Syndrome)
Impact of Myo-Inositol Alone vs Myo-Inositol Plus Metformin on Conception, Adherence, and Tolerability in PCOS
The goal of this clinical trial (prospective randomized controlled trial) is to compare whether myo-inositol alone or in combination with metformin can improve conception rates, treatment compliance, and side-effect profiles in…
- Trial name
- NCT07323589
- Testing
- Myoinositol, Metformin 1500 mg daily
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- PAEC general hospital
Miscarriage
Remnants of Conception After Suction Evacuation of Missed Abortion
All women admitted for surgical evacuation of missed abortion after failure of medical treatment from June 2016 underwent transvaginal sonography immediately after completion of the procedure as judged by the operator to ensure…
- Trial name
- NCT03813849
- Testing
- Sonographic examination of uterus after surgical evacuation
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- University of Alexandria
Retained Products of Conception, Intrauterine Adhesion
Hysteroscopy Assisted Suction Curettage for Early Pregnancy Loss
Retained products of conception (RPOC) and intrauterine adhesions (IUA) may occur following suction curettage for early miscarriage and cause secondary infertility, recurrent pregnancy loss and pregnancy complications.
- Trial name
- NCT04637373
- Testing
- Hysteroscopy
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Chronic Myeloid Leukemia, Pregnancy
Observational Study of Conception/Pregnancy in Adult Patients With CML Treated With Tyrosine Kinase Inhibitors
The objective of this study is to acquire more information about what we are doing during pregnancy in CML patients, in order to possibly establish in the future a consensus on the management of patients receiving TKIs who wants…
- Trial name
- CML1012 (NCT01752062)
- Where
- 52 sites in Italy
- Volunteers
- 148 people
- Sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto
Conception
Sexual Timing in Couples Actively Trying to Conceive
This study will asses the effectiveness of two strategies for timed intercourse in couples actively trying to conceive
- Trial name
- SEXTACTIC (NCT02814006)
- Testing
- health educational video
- Where
- Portugal
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Breast Feeding, Exclusive
Evaluation of Amoxicillin Diffusion in Breast Milk According to a Population Pharmacokinetic Approach (CONCEPTION-AMOX)
Based on plasma and milk concentrations, a PopPK model will be performed (i) to document the average and individual exposure to amoxicillin in milk, (ii) to identify the factors explaining the inter-individual pharmacokinetic…
- Trial name
- CONCEPTION (NCT05051787)
- Testing
- Blood and milk samples
- Where
- 2 sites in France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Natural Conception, Label Comprehension
FERTI-LILY Safety Study
The study is a prospective, 1-arm, open label, nonrandomized, single center study designed to evaluate label comprehension, device usability and safety of the FERTI·LILY Conception Cup.
- Conditions
- Natural Conception, Label Comprehension, Device Usability, Safety Issues
- Trial name
- NCT05529160
- Testing
- FERTI LILY Conception Cup
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Rosesta Medical BV
Shoulder Arthroscopy, İnterscalene Brachial Plexus Block
Comparison of Postoperative Analgesic Efficacy of SPSIPB and Combination of IBPB and SCPB
Shoulder arthroscopy is one of the frequently performed surgical procedures today. After shoulder surgery, ensuring sufficent analgesia is necessary for both the patient's comfort and for the early and regular performance of the…
- Conditions
- Shoulder Arthroscopy, İnterscalene Brachial Plexus Block, Superficial Cervical Plexus Block, Serratus Posterior Superior Intercostal Plane Block
- Trial name
- NCT06660875
- Testing
- Serratus posterior superior intercostal plane block, Interscalene brachial plexus block and superficial cervical plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara Etlik City Hospital
Retained Products of Conception Post Abortion
Oral Contraceptive Pills Versus Expectant Management for Retained Pregnancy Products
We speculate that the use of combined oral contraceptives may be a possible solution to promote the management of retained pregnancy products versus expectant management.
- Trial name
- NCT03230825
- Testing
- Oral contraceptive, Expectant management
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Missed Abortion, Incomplete Abortion
The Role of Uterine Artery Doppler Parameters in the Management of Retained Products of Conception.
During the recent decades the need for surgical evacuation of the uterus in early miscarriages and incomplete miscarriages has been questioned.
- Conditions
- Missed Abortion, Incomplete Abortion, Uterine Gestational Residua, Uterine Artery Doppler
- Trial name
- NCT01775917
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Carmel Medical Center
Infertility, Pregnancy
Lifestyle and Fertility Study on Antioxidant Status, Diet and Early Pregnancy
Researchers believe that certain lifestyle factors can influence a couple's ability to conceive and have a baby. The ISIS Study will look at the health habits of couples who are planning their first pregnancy, and then attempt to…
- Conditions
- Infertility, Pregnancy, Fertility, Nutrition
- Trial name
- NCT00642590
- Where
- 2 sites in United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infant, Premature
Preliminary Study to the Conception of a Non-invasive Neonatal Monitoring System With Development of a Database
Each year, 300 000 new borns are hospitalised in neonatology units in Europe. This period is very sensitive as newborns are exposed to a high risk of morbidity and mortality, with severe impact on neuro-developmental prognostic.
- Trial name
- Digi-NewB (NCT02863978)
- Testing
- Multimodal signal acquisitions
- Where
- 6 sites in France
- Volunteers
- 746 people
- Sponsor
- Rennes University Hospital
HIV/AIDS, HIV Prevention
Helping Men Have Healthy Babies
Many men living with HIV (MLWH) want to have children. HIV-RNA suppression can minimize sexual HIV transmission risks while allowing for conception.
- Trial name
- NCT03818984
- Testing
- Safer Conception for Men with At Risk Partners
- Volunteers
- 28 people
- Sponsor
- Massachusetts General Hospital
Healthy Adult Women of Child Bearing Age
Impact of a MVM to Support Biomarkers Associated With Conception and Pregnancy in Healthy Women.
The goal of this clinical trial is to investigate the effects multivitamin (MVM) on blood biomarkers that are associated with healthy pregnancy and conception in adult women.
- Trial name
- NCT06505408
- Testing
- Multivitamin
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Perelel Inc.
Genetic Anticipation, Immunological Abnormalities
Study of Product of Conception Derived From Ultrasound-guided Manual Vacuum Aspiration
Early pregnancy loss is very common, approximately one in four women will experience a miscarriage in their lifetime. The etiology of pregnancy loss remains largely unknown, although genetic, anatomical, endocrinological and…
- Trial name
- NCT05825183
- Testing
- Ultrasound-guided manual vaccum
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Placental Development Pregnancy Outcome
Peri-implantation Abstinence and Placental Health
This study examined whether avoiding sexual intercourse during the time when a fertilized egg may attach to the uterus affects placental development and pregnancy outcomes.
- Trial name
- NCT07843173
- Testing
- Couples were instructed to avoid sexual intercourse for 14 days after ovulation during each study cycle, covering the expected peri-implantation period.
- Where
- Malaysia
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Prevenetion of Intrauterine Adhesions by Hyaluronic Acid Gel
Intrauterine Hyaluronic Acid Gel for Prevention of Intrauterine Adhesions
Women undergoing operative hysteroscopy for removal of retained placenta after delivery will be randomized into two groups. 1. study group - immediately after operative hysteroscopy 5 ml hyaluronic acid gel will be injected into…
- Trial name
- NCT04975373
- Testing
- Intrauterine injection of hyaluronic acid
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Barzilai Medical Center
Children, ART
Enhancing Management Algorithms for Children Conceived Via Assisted Reproductive Technologies
Research Methods and Ethical Issues 1. Main Scientific Questions and Hypotheses of the Project The primary objective of this project is to investigate the impact of advanced ART methods on the health status of children.
- Conditions
- Children, ART, Anthropometric Characteristics, Somatic Health Status
- Trial name
- NCT07278960
- Testing
- Inhibin B, Anti-Müllerian Hormone (AMH)
- Where
- Kazakhstan
- Volunteers
- 300 people
- Sponsor
- Kazakhstan's Medical University "KSPH"
Asherman Syndrome
Efficiency of Intercoat (Oxiplex/AP Gel)in Decreasing Intrauterine Adhesions
This is a prospective single blind randomized controlled pilot study was designed to investigate whether the biological barrier Intercoat (Oxiplex/AP gel) reduces formation of intrauterine adhesions following hysteroscopic…
- Trial name
- NCT01377779
- Testing
- Oxiplex/AP gel, Normal Saline
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Assaf-Harofeh Medical Center
Aberrant DNA Methylation
Methyl-Donors and EpiGenetics in The Gambia
Accumulating evidence suggests that early-life nutrition can affect metabolism and thus increase the risk of disease in adulthood (e.g. type II diabetes and obesity).
- Trial name
- MDEG (NCT01811641)
- Testing
- season, dietary intake
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Medical Research Council