Clinical trials: Concussion
Mild Traumatic Brain Injury, Internet-Delivered Cognitive Behavioural Therapy
Internet Delivered Cognitive Behavioural Therapy for Persons With Mild Traumatic Brain Injury
Background: Individuals with neurological conditions (stemming from brain injury or stroke) can experience high levels of emotional distress leading to decreased quality of life and increased health care costs.
- Conditions
- Mild Traumatic Brain Injury, Internet-Delivered Cognitive Behavioural Therapy, Depression, Anxiety
- Trial name
- NCT04561011
- Testing
- Internet-delivered Cognitive Behavioural Therapy(ICBT)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Healthy, Concussion (Diagnosis)
Reliability of the SOT Over Clinical Administration Time Intervals of Concussion Assessment
The goal of this study has two parts. First, it examines whether performing multiple Sensory Organization Tests (SOT) on the SMART Balance Master, using two different testing orders, leads to different levels of practice…
- Conditions
- Healthy, Concussion (Diagnosis), Balance Assessment
- Trial name
- NCT07024368
- Testing
- Reliability of the Sensory Organization Test on the SMART Balance Master across multiple administrations
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Hyung Rock Lee
Sport Related Concussion
Salivary Biomarkers for Concussion
Concussion (CC) (also called mild head trauma), which accounts for 85% of all head injuries, is very common in professional and amateur athletes.
- Trial name
- SportCo (NCT06149351)
- Testing
- Bio-fluid analysis for the implementation of a diagnostic test for sport related concussion
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sys2Diag
Sports-related Concussion
The Impact of Riboflavin on Sports-related Concussion
The purpose of this study is to investigate the effectiveness of riboflavin to decrease the duration of time for a student-athlete to return to participation in sports after a sports related concussion.
- Trial name
- NCT02772237
- Testing
- Riboflavin
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Brain Concussion
Cerebral Microstructural Changes Following Mild Traumatic Brain Injury
This study examine the possible microstructural changes in the middle brain after mTBI using diffusion MRI
- Trial name
- NCT02331901
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Concussion, Mild, Post-Concussion Symptoms
Bright Light Therapy for Treatment of Sleep Problems Following Mild Traumatic Brain Injury
The purpose of the research study is to understand the effectiveness of a six-week course of light exposure on cognitive functioning, mood, activity, and sleep in people that have suffered a head injury leading to a concussion.
- Conditions
- Concussion, Mild, Post-Concussion Symptoms, Sleep Problems
- Trial name
- NCT02374918
- Testing
- mTBI wavelength-1 bright light, mTBI wavelength-2 bright light, HC wavelength-1 bright light
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Arizona
mTBI, Concussion
Quantification of Balance in Acutely Concussed Athletes
The purpose of this pilot project is to determine whether using inertial sensors placed on the waist during routine clinical balance testing (i.e.
- Conditions
- mTBI, Concussion, Mild Traumatic Brain Injury
- Trial name
- NCT01661075
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Traumatic Brain Injury, Mild Traumatic Brain Injury
Brain Research Assessing Impacts of Neurophysiological Processing Speed Training in Veterans
Older veterans with a history of mild brain trauma exhibit early cognitive challenges, especially in driving-related tasks. This is attributed to alterations in the brain's excitatory/inhibitory (E/I) balance.
- Conditions
- Traumatic Brain Injury, Mild Traumatic Brain Injury, Aging, Cognitive Decline
- Trial name
- BRAIN-SPEED (NCT06217575)
- Testing
- Alpha neurofeedback training, Visual Attention Training
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Craniocerebral Trauma
The Acute Effect of Boxing on Balance, Neuropsychological, and Visual Functions
Prior research has investigated the effect of repetitive head trauma as it relates to physiological and psychological function. Boxing is one particular sport which predisposes athletes to a large amount of head impacts.
- Trial name
- NCT02442882
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Concussion, Mild, Post-Concussion Symptoms
Effects of Bright Light Therapy in Mild Traumatic Brain Injury
Mild traumatic brain injuries (mTBI) or "concussions" are an increasingly prevalent injury in our society. Patients with post-concussion syndrome have been shown to have deficits on tests of short term memory, divided attention…
- Conditions
- Concussion, Mild, Post-Concussion Symptoms, Sleep Problems
- Trial name
- NCT01747811
- Testing
- wavelength-1 bright light, wavelength-2 bright light
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Mild Traumatic Brain Injury, Concussion, Binocular Visual Function
An Early Prospective Study of the Traq™ Device for Characterization of Binocular Ocular Function in Normal Subjects and Subjects With Recent Traumatic Brain Injury
The early prospective study of Traq™ (an investigational binocular ophthalmic neurodiagnostic device) will measure binocular ocular functions (bilateral foveal fixation, foveal binocularity, and fovea-tracked saccadic latency) in…
- Conditions
- Mild Traumatic Brain Injury, Concussion, Binocular Visual Function, Neuro-Ophthalmology, Saccadic Eye Movements
- Trial name
- REB-001 (NCT07742878)
- Testing
- Binocular ophthalmic neurodiagnostic device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Traumatic Brain Injury, Concussion, Brain
Understanding Concussion/Mild Traumatic Brain Injury
Using the Blink Reflexometer, athletes are scanned if they are potentially thought to have a concussion during a game or practice.
- Trial name
- NCT03381638
- Testing
- Blink Reflexometer
- Where
- 5 sites in United States
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- Blinktbi, Inc.
Concussion
Vascular Assessment of Regulation Index Arrays Registry
The objective of this patient registry is to collect and analyze physiological data associated with baseline and brain injury identified in standard clinical practice (Normal Values, Recovery Curves, Correlation between Symptoms…
- Trial name
- VARIA (NCT02435082)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- NeuroChaos Solutions, Inc.
Traumatic Brain Injury, Concussion, Brain
" Acute Brain Changes After Repetitive Headers in Soccer and the Effects of a Protective Device "
Soccer, the most popular sport in the world, exposes players to repeated head impacts and concussions, due to contact with another player or with the ground.
- Trial name
- Soccer-BRAIN (NCT04426188)
- Testing
- Heading series, Magnetic Resonance Imaging (MRI), Cognitive computerized assessment
- Where
- France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Brain Injuries, Traumatic, Concussion, Mild
Objective Brain Function Assessment of mTBI/Concussion
This study (Part 3) is designed to build a database including EEG, neurocognitive performance, clinical symptoms, history and other relevant data, which will be used to derive a multimodal EEG based algorithm for the…
- Conditions
- Brain Injuries, Traumatic, Concussion, Mild, Concussion, Intermediate, Concussion, Severe
- Trial name
- CAS13-25 (NCT03963804)
- Testing
- BrainScope Ahead 300iP
- Where
- 4 sites in United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- BrainScope Company, Inc.
Post-Concussion Syndrome
Rehabilitation in Post Concussion Syndrome
This project evaluates and quantifies the effects of an individually tailored exercise program applied to patients with long-lasting symptoms after concussion, minor traumatic brain injury, so-called Post-Concussion Syndrome…
- Trial name
- REPCon (NCT05785000)
- Testing
- Physical exercise programme as an add-on, Control patients receiving usual care
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Brain Concussion, Posttraumatic Stress Disorder
Brain Injury Outcomes (BIO) Study
Many active duty military, national guard, and reserves personnel who served in the recent conflicts in Afghanistan and Iraq were exposed to blasts and other mechanisms of traumatic brain injury (TBI).1,2 Although physical trauma…
- Conditions
- Brain Concussion, Posttraumatic Stress Disorder, Dementia
- Trial name
- BIO (NCT00724607)
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Mild Traumatic Brain Injury, Suicide Prevention
Crisis Response Planning in Military Personnel With Mild Traumatic Brain Injury
The study purpose is to test the effect of Crisis Response Planning (CRP) when used as the second method of suicide prevention in military service members who are at risk for suicide due to mild traumatic brain injury (mTBI).
- Conditions
- Mild Traumatic Brain Injury, Suicide Prevention, Suicide Risk | Patient, Suicide Risk
- Trial name
- NCT07327567
- Testing
- Crisis Response Planning
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Post-Concussion Syndrome
Craniosacral Therapy for Concussion Symptoms
This study investigated the utilization of CranioSacral Therapy (CST) in patients with Post-Concussion Syndrome (PCS) and capture patient-reported perceptions of their lived experiences of treatment effect upon their symptoms.
- Trial name
- NCT04820192
- Testing
- Craniosacral Therapy
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Special Therapies, Inc.
Healthy
Naturally Produced Cannabinoids for Neuroprotection From Concussion
The goal of this double-blind, placebo-controlled, cross over study is to learn about the neuroprotective properties of a broad-spectrum cannabinoid formulation in normal healthy adults engaged in elite contact sport competition.
- Trial name
- NCT07715864
- Testing
- Broad spectrum cannabinoid formulation
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Regina