Clinical trials: Concussions
Pediatric ALL, Concussion, Mild
Concussion Active Rehabilitation
In this study, the investigator plans a randomized trial of active rehabilitation and standard care for acute concussion management.
- Conditions
- Pediatric ALL, Concussion, Mild, Concussion, Brain, Concussion, Intermediate
- Trial name
- NCT04248218
- Testing
- Active Rehabilitation Group/Case
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Mild Traumatic Brain Injury
Photobiomodulation for Concussions: the Use of the ImPACT® Test as an Assessment Tool
Brain photobiomodulation (PBM) therapy is an innovative modality for the stimulation of neural activity in order to improve brain function and is currently under investigation as a treatment for several diverse neurological…
- Trial name
- NCT04823507
- Testing
- BIOFLEX DUO+
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Meditech Rehabilitation Centre
Brain Concussion, Post-Concussion Syndrome
Cerebral Blood Flow Regulation and Concussions
The purpose of this study is to understand how biochemical markers in blood, balance disturbances, and cognitive performance are related to brain blood flow changes after a concussion.
- Trial name
- NCT02754206
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Southern Methodist University
Sports-related Concussion
Impact of Sports-related Concussions on the Attention and Executive Skills of Adolescents and Young Adults: Links With Subjective Symptoms and Recovery
Concussion in sports ("Sports-Related Concussion" or "SRC") are a public health issue. The management of these injuries is evolving rapidly and decisions to return to play are based on clinical judgment.
- Trial name
- EXAECOS (NCT03914833)
- Testing
- Inclusion Questionnaires, Questionnaires at inclusion, M1 and M3
- Where
- France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Sports-related Concussion
Harmonization and Implementation of Sports-related Concussion Guidelines in European Football for Youth - the Erasmus + Project
This study addresses the evident gap in SRC awareness and reporting, especially at the grassroots level, by harmonizing concussion management practices across Europe and observing its impact on stakeholders' (coaches, parents…
- Trial name
- REFORM (NCT07128706)
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Brain Injuries, Concussion, Brain
The Monaco Initiative for Concussion in Motorsport Pilots
The study aims: to observe a population particularly exposed by the past to brain trauma and concussion: Motorsport Pilots who are retired from a professional practice of motor sport; to report results of their neuro-cognitive…
- Conditions
- Brain Injuries, Concussion, Brain, Sport Injury
- Trial name
- NCT04730167
- Testing
- Neurological and neuropsychological assessments / MRI / PET scan / Video-oculography.
- Where
- Monaco
- Volunteers
- 12 people
- Sponsor
- Association de Recherche Bibliographique pour les Neurosciences
Sports Concussion
Use of Resveratrol to Decrease Acute Secondary Brain Injury Following Sports-Related Concussions in Boxers
Sports-related concussions are a serious problem in football, boxing, and other full contact sports. After experiencing consecutive concussions, there is an increase in neurological deficits that can lead to long-term cognitive…
- Trial name
- REPAIR (NCT01321151)
- Testing
- Resveratrol
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Concussions
COmmunities Aligned to Reduce Concussion and Head Impact Exposure
Head impacts in collision sports such as football are a public health concern, as repetitive head impacts, even if a concussion is not suspected, have negative effects on brain health.
- Trial name
- COACH (NCT06624202)
- Testing
- COmmunities Aligned to reduce Concussion and Head impact exposure (COACH) Intervention
- Where
- United States
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Mild Concussion, Brain Concussion
High Dose Omega-3 Fatty Acids in the Treatment of Sport Related Concussions
Concussions are defined as a complex pathophysiological process affecting the brain, induced by traumatic biomechanical forces. Currently the standard of care in the treatment for concussions is cognitive and physical rest until…
- Conditions
- Mild Concussion, Brain Concussion, Cerebral Concussion
- Trial name
- NCT01814527
- Testing
- Docosahexaenoic acid
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- East Carolina University
Concussions, PCS
Predicting Persistent Postconcussive Problems in Pediatrics (5P)
Concussion, a mild traumatic injury common in children and adolescents, is a complex pathophysiological process affecting the brain.
- Trial name
- 5P (NCT01873287)
- Where
- 9 sites in Canada
- Volunteers
- 3,063 people
- Sponsor
- Children's Hospital of Eastern Ontario
Sport Medicine
ATI Evidence-based Guide Investigating Medical and Preventative Services
To use existing standard-of-care documentation in a sports medicine electronic medical record (EMR) to evaluate patient characteristics, interventions delivered, utilization management, and clinical outcomes in routine sports…
- Trial name
- NCT04050319
- Testing
- Screening and diagnosis if injured
- Where
- United States
- Volunteers
- 550,000 people, healthy volunteers welcome
- Sponsor
- ATI Holdings, LLC
Concussions
Longitudinal Study of Children With Concussions
For children and adolescents who have had a concussion resulting in prolonged symptoms (>3 months), the investigators will: 1. Measure post-concussion symptoms, cognitive and emotional function during the 3 years post-injury. 2.
- Trial name
- NCT03415048
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Concussion
Cortical Plasticity Assessment in Athletes With a History of Concussion
The purpose of this research is to determine whether athletes with concussion have changes in cortical excitability. Single and paired transcranial magnetic stimulation (TMS) can be used as reliable neurophysiological marker of…
- Trial name
- NCT01112761
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Concussions, Mild Traumatic Brain Injury, Concussion
Mindfulness-Based Intervention for Pediatric Mild Traumatic Brain Injury
Formal MBIs, such as Mindfulness-Based Stress Reduction (MBSR), have been shown to increase resiliency and teach affect regulation.
- Conditions
- Concussions, Mild Traumatic Brain Injury, Concussion, Concussion Mild
- Trial name
- MBI-4-mTBI (NCT07272941)
- Testing
- Mindfulness Based Intervention (MBI)
- Where
- 5 sites in Canada
- Volunteers
- 362 people
- Sponsor
- Children's Hospital of Eastern Ontario
Cognitive Deficits, Proprioceptive Disorders
Effects of Multiple Concussions in Retired NHL Players
To investigate long term affects of multiple concussions on the cognition, balance, proprioception, and biomarkers in retired National Hockey League players
- Trial name
- NHL (NCT02746523)
- Testing
- Sensory Organization Test, Biomarkers, Conners' Adult ADHD Rating Scale (CAARS)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Sports-related Concussions, Selective Head-neck Cooling, Return to Play
Medical Cooling of Ice Hockey Players
The incidence of Sports-related concussions (SRCs) has risen in recent years, not least in ice hockey, and available treatment options are limited.
- Trial name
- NCT04701125
- Testing
- selective head-neck cooling using PolarCap system
- Where
- Sweden
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Region Skane
Concussion, Brain
Objective Concussion Assessment Using MRI and Metabolomics
Mild traumatic brain injury (mTBI), also referred to as concussions, affect millions of people around the world and can cause harmful long term effects.
- Trial name
- NCT05993351
- Testing
- Magnetic resonance imaging (MRI), Urine and saliva samples, Questionnaires
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Concussion, Brain, Musculoskeletal Pain
The Impact of Eye and Body Training on the Injury Rate of Concussions in Female Soccer Players
The research project aims to find out how special training influences the frequency and severity of injuries among female footballers in the top Swiss league.
- Trial name
- NCT06473883
- Testing
- Training recommendation
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- BrainCare Medical Group
Concussion, Headache
Sphenopalatine Ganglion Block for Headache After Concussion
This clinical trial will enroll participants to evaluate the effects of SPG block on post-traumatic headache. The study hypothesizes that patients that receive a SPG block with lidocaine vs.
- Trial name
- NCT04650282
- Testing
- Lidocaine in SphenoCath device, Saline Solution in SphenoCath device
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Michigan
Concussion, Mild
Reverse King-Devick Test and History of Multiple Concussions
The purpose of this study is to examine the effects of concussion history and reading direction on baseline King- Devick Test (KDT) performance, a common component of sideline concussion assessments.
- Trial name
- NCT04560400
- Testing
- Conventional King-Devick test, Reverse King-Devick test
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Indiana University