Clinical trials: Condition
Overweight, Obesity
Mono Unsaturated Fatty Acids in Obesity - Weight Maintenance and Prevention of Lifestyle Diseases in Obese Subjects.
The purpose of this study is to investigate the effect of three diets different in type and amount of fat in weight maintenance and prevention of life-style diseases in obese subjects.
- Trial name
- NCT00274729
- Testing
- Mono Unsaturated Fatty Acids in Obesity
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy, Obesity
Open Label Randomized Clinical Study to Promote a Healthy Lifestyle in Medical Students
The main medical and social purpose of the project "It's trendy to be healthy!" is the promotion of healthy lifestyles and healthy eating among student youth.
- Conditions
- Healthy, Obesity, Nutrition, Healthy, Vitamin D Deficiency
- Trial name
- NCT05073029
- Testing
- nutrition program and modification of physical activity, synbiotic (Fructooligosaccharides+Lactobacillus rhamnosus GG ATCC 53103, 4.0х109 colony forming units - CFU), vitamin D3
- Where
- 2 sites in Ukraine
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bogomolets National Medical University
Aortic Valve Stenosis
Metabolic Determinants of the Progression of Aortic Stenosis
Calcific aortic stenosis (AS) has become the most common cardiac disease after coronary artery disease and hypertension. Unfortunately no medical therapies have been proven to decrease either the progression of valve stenosis or…
- Trial name
- PROGRESSA (NCT01679431)
- Testing
- Doppler-echocardiography, Computed tomography, Magnetic resonance imaging
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Laval University
ADPKD (Autosomal Dominant Polycystic Kidney Disease)
Mass Balance and Absolute Bioavailability Study of JMKX003142 In Healthy Volunteers
A phase 1 healthy volunteer study to assess the excretion and metabolism as well as the absolute bioavailability of oral JMKX003142.
- Trial name
- NCT07463053
- Testing
- [14C]JMKX003142, JMKX003142 tablets, [14C]JMKX003142 solution for infusion
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Jemincare
Elevated Intraocular Pressure (IOP)
Clinical Investigation of Eye C Better's Photobionic Intraocular Pressure Biomonitor Tonometer
The device being studied in this research is the investigational PIB, a tool designed to measure eye pressure without touching the eye.
- Trial name
- PIB (NCT07762053)
- Testing
- Photobionic IOP Tonometer (PIB)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- EyeCBetter Corporation
Cardiovascular Diseases, Rheumatologic Disease
Greater Manchester CARDIOvascular Pathology in Immune-Mediated Inflammatory Diseases
The researchers would like to know more about cardiovascular abnormalities in patients with immune-mediated inflammatory diseases (IMID) and with the aim to provide new biomarkers (clinical, blood, imaging) for early diagnosis…
- Trial name
- GM CARDIO-IMID (NCT06600737)
- Where
- United Kingdom
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Lynch Syndrome, Crohn Disease
A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule
The investigators have developed an inexpensive tool to take pictures in the lower GI tract without sedation and to look for signs of disease.
- Conditions
- Lynch Syndrome, Crohn Disease, Inflammatory Bowel Diseases, Healthy
- Trial name
- NCT07219537
- Testing
- Feasibility of using an OCT-based Retrograde Tethered Capsule Endomicroscope device to image the lower GI tract
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Infection
Allergy Antibiotics And Microbial Resistance
ALBAMA study is designed to find out if the effects of Penicillin allergy assessment pathway (PAAP) intervention is on penicillin prescribing
- Trial name
- ALABAMA (NCT04108637)
- Testing
- penicillin allergy assessment pathway
- Where
- United Kingdom
- Volunteers
- 823 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Type2 Diabetes, Obesity
Glucose Metabolism in Brown Adipose Tissue (BAT) in Young Healthy Men Evaluated by Deuterium Metabolic Imaging (DMI)
In this study the investigators wish to evaluate the glucose metabolism in brown adipose tissue (BAT) in young healthy men (aged 18-35).
- Conditions
- Type2 Diabetes, Obesity, Metabolic Syndrome
- Trial name
- NCT04060745
- Testing
- cooling using a water-perfused vest, thermoneutrality
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Type 2 Diabetes
INVESTIGATION OF THE EFFECT OF DIFFERENT ACTIVATION TECHNIQUES ON TLR9, IL6, IL10, TNF-ALFA LEVELS IN HEALTHY AND TYPE 2 DIABETIC PATIENTS WITH APICAL PERIODONTITIS REQUIRING RETREATMENT
The subject of this thesis study is the effects of SWEEPS laser and ultrasonic activation methods on the immune response in the treatment of apical periodontitis in healthy individuals and patients with Type 2 diabetes requiring…
- Trial name
- TLR9 in T2DM (NCT07389772)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- bengisu yüksel
Obesity (BMI>30), Insulin Resistance
Peripheral Vascular Effects of Insulin in Obesity
Successful completion of this project will advance our understanding of the role sympathetic nervous system overactivity plays in driving skeletal muscle malperfusion during hyperinsulinemia and consequently impaired glucose…
- Trial name
- NCT07874945
- Testing
- human insulin
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Telementoring Intervention (ECHO) for the Transformation of Professional Engagement, Practice Efficiency, and Community Building Through Team Meetings in Diagnostic Imaging Clinicians
This trial studies how well the Extension for Community Healthcare Outcomes (ECHO) telementoring intervention works in transforming professional engagement, practice efficiency, and community building through team meetings in…
- Trial name
- NCT04196972
- Testing
- Communication Intervention, Questionnaire Administration, Waiting List
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cannabis, Abuse Liability
Repeated CBD Administration and Cannabis Outcomes
This outpatient study examines how cannabidiol (CBD) affects the behavioral and pain-relieving effects of cannabis.
- Conditions
- Cannabis, Abuse Liability, Experimental Pain in Healthy Human Participants
- Trial name
- NCT07434895
- Testing
- Cannabidiol, Medium Dose, Cannabidiol, Higher Dose, Active Inhaled Cannabis
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Hannah Harris
Cardiovascular Disease (CVD) Risk Factors
Empowering Cardiovascular Health in Custodial Grandparents
In this study, the investigators will tailor an existing intervention (Rural Caregiver Heart Health Education (RICHH)) protocol and test its feasibility, acceptability, and initial effect with grandparent caregivers.
- Trial name
- ECG (NCT07083895)
- Testing
- Modified RICHH, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
COVID-19, Asymptomatic Pregnant
COVID-19 PCR Test Results in Asymptomatic Pregnants
In order to prevent contamination from the pregnant women hospitalized in this clinic, the RT-PCR test is performed from the oropharyngeal and nasal swab sample taken before hospitalization.
- Trial name
- NCT04410939
- Testing
- Reverse transcription polymerase chain reaction
- Where
- Turkey (Türkiye)
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Unilateral Vocal Cord Paralysis
Early UVFP Management Based on Neurological Evidences (UVFP = Unilateral Vocal Fold Paralysis)
The aim of this study is to understand how early intervention could impact reinnervation of the recurrent laryngeal nerve (which innervates the vocal cord), recovery of mobility of the paralyzed vocal cord and / or vocal recovery…
- Trial name
- IONS-UVFP (NCT03906877)
- Testing
- Acid hyaluronic injection laryngoplasty, Voice therapy
- Where
- Belgium
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Preeclampsia, Gestational Hypertension
Evaluation of sFlt-1/PlGF Ratio ,OPG and sEng as Predictive Biomarkers in the Diagnosis and Treatment Evaluation of Preeclampsia
his study investigates the effectiveness of three specific biological markers (biomarkers) in the blood-the sFlt-1/PlGF ratio, soluble endoglin (sEng), and osteoprotegerin (OPG)-to better diagnose and monitor preeclampsia.
- Conditions
- Preeclampsia, Gestational Hypertension, Hypertensive Disorders of Pregnancy
- Trial name
- PE-POSS (NCT07349277)
- Where
- Iraq
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ammar Jassim Abed
Poliomyelitis
Assessing Immunogenicity of Intramuscular Sabin Inactivated Poliovirus Vaccine and Non-inferiority of Intradermal Fractional Inactivated Poliovirus Vaccine
This is an open label and off label, phase IV, randomized clinical trial that will compare the immune response among infants that receive either two full doses of Sabin IPV intramuscularly or two fractional (1/5) dose of Sabin…
- Trial name
- NCT05460377
- Testing
- Full dose Sabin Inactivated Poliovirus Vaccine produced by IMBCAMS, Fractional (1/5) Dose Sabin Inactivated Poliovirus Vaccine produced by IMBCAMS, Full dose Sabin Inactivated Poliovirus Vaccine produced by BIBP
- Where
- Bangladesh
- Volunteers
- 1,224 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Children Who Need Circumcision
Assessment of Hemodynamic Response in Surgery of Circumcision in Children
The surgery stress relives systemic inflammatory response by hormones and adrenergic receptors. When the pro-inflammatory mediator is higher than anti-inflammatory response, the physiologic status is impaired and the patient is…
- Trial name
- NCT00943475
- Testing
- circumcision
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of Juiz de Fora
Autism Spectrum Disorders
Cortical Metrics in Intervention Trials With Autism Spectrum Disorders
The investigators overarching aim is to obtain preliminary data to support a larger grant to validate a novel objective, physiologically-based outcome measure for clinical trials in autism spectrum disorders (ASDs) called the…
- Trial name
- NCT02212275
- Testing
- Dextromethophan
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
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