Clinical trials: Condition
Patient Education, Surgical Fear and Worrying
The Effect of Video-Supported Online Preoperative Education on Fear, Anxiety, Sleep, and Stress
Gallbladder stone disease is among the most common digestive system problems worldwide. The global incidence of gallstones is estimated to be 10-20%. In Europe, this rate is approximately 20%.
- Conditions
- Patient Education, Surgical Fear and Worrying, Surgical Stress Response, Medical-surgical Nursing
- Trial name
- NCT07100275
- Testing
- Patient education, Follow-up via Mobile Health Application
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Bingol University
Multiple Myeloma, Low-Grade Lymphoma
64Cu-LLP2A for Imaging Hematologic Malignancies
This phase of the protocol (protocol part B), seeks to evaluate the new formulation in healthy normal volunteers to confirm the new formulation provides comparable human dosimetry to which was seen and published in protocol part…
- Conditions
- Multiple Myeloma, Low-Grade Lymphoma, Follicular Lymphoma, Marginal Zone Lymphoma
- Trial name
- NCT06636175
- Testing
- 64Cu-LLP2A, PET/CT
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Pulsatile Tinnitus
The Recurrence Mechanism of Venous Tinnitus After Boney Wall Reconstruction Based on Multimodal Imaging and Multiphysics Coupling
Venous tinnitus (VT) is seriously affecting the quality of life of five million patients in China. Bony wall reconstruction is the main treatment method, but the postoperative recurrence rate exceeds 30%, and the specific…
- Trial name
- NCT05856175
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Aneurysm
Captopril Versus Atenolol to Prevent Expansion Rate of Thoracic Aortic Aneurysms
Thoracic aortic aneurysms (TAA) are considered "silent killers" because they scarcely display any symptomatology, but are correlated with significant mortality and morbidity.
- Trial name
- NCT04224675
- Testing
- Atenolol
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Onassis Cardiac Surgery Centre
Artificial Intelligence
AI-assisted Gastroscopic Varicose Vein Diagnosis
Validation of the accuracy of AI in assisting gastroscopic varices diagnosis through a prospective multicenter study
- Trial name
- NCT05293457
- Where
- China
- Volunteers
- 793 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
MeSH
Comparison of the Effectiveness of Sambiloto Herbs (Andrographis Paniculata) and Brisk Walking Exercise on Blood Glucose of Obese Patients
Problem Formulation 1. Does herbal medicine sambiloto affect the blood glucose levels of obese sufferers? 2. Does brisk walking affect blood glucose levels in obese sufferers? 3.
- Trial name
- NCT06520501
- Testing
- Herbal Medicine Sambiloto, Brisk Walking, Brisk Walking and Herbal Medicine Sambiloto
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Palangka Raya
Sports Physical Therapy
WB-EMS Increase Energy Expenditure at Rest and During Uphill Walking Exercise
Whole-body electrical stimulation (WB-EMS) has become increasingly popular as a tool to provide additional benefits compared to conventional exercise.
- Trial name
- NCT05218512
- Testing
- WB-EMS
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Malaria
A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)
The purpose of this study is to assess the antimalarial activity, pharmacokinetics, and safety of MK-7602 in healthy adults following Plasmodium falciparum (P. falciparum) infection.
- Trial name
- NCT06294912
- Testing
- Plasmodium falciparum, MK-7602, Artemether/lumefantrine
- Where
- Australia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Communication Disabilities
Improving Communication and Healthcare Outcomes for Patients With Communication Disabilities
In the United States, 14% of all adults report a speech, language, voice, and/or hearing disability (collectively known as communication disabilities, CD).
- Trial name
- NCT04697212
- Testing
- Healthcare team- + patient-directed intervention, Healthcare team-directed intervention
- Where
- 5 sites in United States
- Volunteers
- 687 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Entrapment Neuropathy, Rotator Cuff Tear
Suprascapular Neuropathy in the Setting of Rotator Cuff Tears: Results of Arthroscopic Treatment
Aim of this prospective double blind randomized clinical trial is to understand the correlation of suprascapular neuropathy in the setting of large and massive tears of the shoulder rotator cuff and to investigate whether…
- Trial name
- SupraCufTear (NCT02318381)
- Testing
- Dissection of the superior transverse scapular ligament
- Where
- Greece
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Obesity, Childhood
MEditerranean LIfestyle in Pediatric Obesity Prevention
The current project is a randomized controlled multi-centre clinical trial, in a cohort of children aged 3 to 6 years at baseline and being at obesity risk.
- Trial name
- MELI-POP (NCT04597281)
- Testing
- Lifestyle intervention
- Where
- 3 sites in Spain
- Volunteers
- 738 people, healthy volunteers welcome
- Sponsor
- Luis A. Moreno Aznar
Hypertension
A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1015" and Co-administration of "BR1015-1" and "BR1015-2" Under Fasting Conditions in Healthy Volunteers
The purpose of this clinical trial is to evaluate the pharmacokinetics and the safety after administration of "BR1015" and co-administration of "BR1015-1" and "BR1015-2" under fasting conditions in healthy volunteers
- Trial name
- NCT06008028
- Testing
- BR1015, BR1015-1, BR1015-2
- Where
- South Korea
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Trigeminal Neuralgia, Trigeminal Nerve Diseases
Artificial Intelligence to Predict Surgical Outcomes and Assess Pain Neuromodulation in Trigeminal Neuralgia Subjects
Trigeminal neuralgia (TN) is the most common cause of facial pain. Medical treatment is the first therapeutic choice whereas surgery, including Gamma Knife radiosurgery (GKRS), is indicated in case of pharmacological therapy…
- Conditions
- Trigeminal Neuralgia, Trigeminal Nerve Diseases, Virtual Reality, Artificial Intelligence
- Trial name
- NCT05810428
- Testing
- GKRS-VR training, Control Group
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Pain, Hematuria
Diclofenac Suppository to Control Pain During Flexible Cystoscopy
Flexible cystoscopy has diagnostic as well as therapeutic role in many patients presenting in urology clinic with lower urinary tract symptoms (frequency, nocturia etc) and hematuria (blood in urine).
- Conditions
- Pain, Hematuria, Lower Urinary Tract Symptoms
- Trial name
- DUF (NCT01812928)
- Testing
- Diclofenac
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Multiple Sclerosis, Healthy Controls
Multiple Sclerosis: Associated Cardiometabolic Risks and Impact of Exercise Therapy
Multiple Sclerosis (MS) is the most common chronic inflammatory neurological disorder in young adults. Due to heterogeneous symptoms, MS patients are often more inactive than healthy controls, resulting in an inactivity related…
- Trial name
- NCT02466165
- Testing
- Physical exercise
- Where
- 2 sites in Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bert Op't Eijnde
Relative Energy Deficiency in Sport
Evaluation of a Practice-oriented Recovery Program for Female Endurance Athletes With Relative Energy Deficiency
The aim of this study is to develop, implement and evaluate the effects of a 16 week practice orientated sports nutrition education and counselling program aiming to improve energy availability and to investigate the effects on…
- Trial name
- NCT04959565
- Testing
- Nutritional behavioral intervention
- Where
- 4 sites in Germany, Ireland and 2 more
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Monica Klungland Torstveit
Renal Stone, Pediatric
Flexible Ureteroscopy Versus Mini- Percutaneous Nephrolithotomy in Management of Pediatric Renal Stones Less Than 2 cm
This single-center, prospective, two-arm randomized controlled trial included 58 patients younger than 18 years who were allocated 1:1 to Mini-PCNL or FURS between June 2023 and December 2024.
- Trial name
- NCT07870200
- Testing
- Group A :Flexible ureteroscope group, Group B : Mini perc group
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Elsayed Abdelhalim Elsayed
Dental Crowding, Alveolar Bone Loss
Bone Level Changes Using Clear Aligners Compared to Fixed Appliances in Non-Extraction Treatment of Adults
This study compares two common ways of straightening teeth in adults who have mild-to-moderate crowding of the lower front teeth and do not need any teeth removed: clear aligners and traditional fixed braces.
- Conditions
- Dental Crowding, Alveolar Bone Loss, Malocclusion
- Trial name
- NCT07716007
- Testing
- Fixed orthodontic appliance, Clear aligners
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Heart Defects, Congenital
Body Water Content in Cyanotic Congenital Heart Disease
Adults with cyanotic congenital heart disease have elevated levels of plasma proatrial natruretic peptide (proANP) which most likely results in chronic dehydration, leading to reduced oxygen transport to tissues and shortness of…
- Trial name
- NCT00000107
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Pregnant Woman
Monitoring of Incidence of Mental Discomfort in Pregnant Women During the Serious COVID-19 Pandemic Conditions
This study is aimed to detect severe fear of delivery and its association with the incidence of obsessive-compulsive disorder and symptoms of depression and anxiety in the population of pregnant women in the third trimester…
- Trial name
- COTEPS (NCT04898192)
- Testing
- questionnaire
- Where
- Slovakia
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Comenius University
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