Clinical trials: Condition
Medical Device Site Injury, Pressure Injury
Prevent Medical Device-Related Pressure Injury
Medical Device-Related Pressure Injury (MDRPI) is a localized skin and/or subcutaneous tissue injury that occurs due to the pressure exerted by devices used for diagnostic or therapeutic purposes, taking the form of the medical…
- Trial name
- NCT06563830
- Testing
- educational application
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Pain, Depression
Stepped Care for Depression and Musculoskeletal Pain
This study will evaluate the effectiveness of a stepped care approach in treating depression and reducing pain.
- Trial name
- NCT00118430
- Testing
- Stepped Care, Antidepressants, Usual Care
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Indiana University
Muscle Atrophy, Surgery
Use of Testosterone to Prevent Post-Surgical Muscle Loss - Pilot Study
The loss of muscle mass post-surgery confounds recovery efforts and leads to a delay in patient's ability to return to activities.
- Conditions
- Muscle Atrophy, Surgery, Knee Injuries and Disorders, Complication of Surgical Procedure
- Trial name
- NCT04456530
- Testing
- Aveed 750 MG in 3 ML IM Injection, Normal Saline 3 ML IM Injection
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The Stone Research Foundation for Sports Medicine and Arthritis
Osteoarthritis, Knee
Evaluation of the Effectiveness of Manual Therapy in Patients With Knee Osteoarthritis
The aim of this study is to investigate the effects of three different applications (Manual therapy, electrotherapy and home program) on long-term pain, joint range of motion and, secondarily, the functional level of the knee.
- Trial name
- NCT06329128
- Testing
- Experimental: Study Group, Active Comparator: Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Post Treatment Lyme Syndrome (PTLS), Chronic Pain
Uncovering Neural and Immune Mechanisms of Chronic Pain in Post Treatment Lyme Syndrome
This study will investigate (a) neural and immune mechanisms underlying chronic pain in PTLS by comparing a group of PTLS patients and healthy participants on brain imaging, sensory, and immune markers; and (b) assess change in…
- Trial name
- PTLS (NCT02687165)
- Testing
- Milnacipran and D-cycloserine
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Fibromyalgia, Chronic Pain
Tai Chi Intervention and Brain Imaging Study Among Fibromyalgia Patients and Healthy Controls
This exploratory study proposal is the first pilot brain imaging study to determine if Tai Chi can modulate brain resting state functional connectivity (rsFC) and brain morphometry among fibromyalgia (FM) patients and healthy…
- Trial name
- fMRI/FMEX (NCT02407665)
- Testing
- Tai Chi
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
MTBI - Mild Traumatic Brain Injury, Concussion, Mild
Controlled DTI Evaluations in High School Football and Female Soccer to Evaluate Efficacy of Jugular Compression Collar
The purpose of the study is to monitor longitudinal changes in brain structure between the preseason and postseason, in a population of football and soccer playing athletes wearing the Device and compared to a similar population…
- Trial name
- NCT04068883
- Testing
- Q collar
- Where
- 2 sites in United States
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
COVID-19 Pandemic
Fourth BNT162b2 COVID-19 Vaccine Dose
The Omicron variant of concern (VOC) is currently rapidly spreading worldwide, with extremely high transmission rates, with an estimated R of >3.
- Trial name
- NCT05231005
- Testing
- BNT162b2 vaccine
- Where
- Israel
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Pneumonia
Effects of the Oral Care With Vaccines for Pneumonia in Elderly; Going Home Together Both Physician and Dentist
Prospective study comparing the effects of interventions (combined oral care and pneumococcal plus influenza vaccinations) in preventing pneumonia and increasing the survival rate from pneumonia.
- Trial name
- NCT01403805
- Testing
- Pneumococcal vaccination (Pneumovax NP, 21800AMY10131000), Influenza vaccination (Flubik HA, 16100EZZ01207000), Specific frequency of oral care
- Where
- Japan
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Yubari Kibounomori
Eating Disorders, Female Athlete Triad
Efficacy of the Female Athlete Body Project (FAB)
Given the cost of treating eating disorders and the substantial morbidity and mortality associated with these disorders, prevention of eating disorders has considerable public health significance.
- Trial name
- FAB (NCT01735994)
- Testing
- Healthy Weight, Brochure
- Where
- United States
- Volunteers
- 481 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Opioid Use Disorder
Social Functioning in Opioid Use Disorder
Problems with social functioning are core to opioid use disorder (OUD), though specific, modifiable social functioning targets and how they relate to OUD treatment outcomes are poorly understood.
- Trial name
- OUD (NCT07044466)
- Testing
- CBT4CBT-Buprenorphine
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Diabetes, Surgery Related Complications Rate
Preoperative Optimization of Diabetic Patients
Diabetic patients, as part of preoperative evaluation, should have glycated hemoglobin (HbA1C) measured. HbA1C provides information on longterm glucose control.
- Trial name
- NCT06589466
- Testing
- Surgery
- Where
- Canada
- Volunteers
- 46,000 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Psychological Disorder
Understanding the Impact of Death Conditions Linked to the COVID-19 Crisis on the Grieving Process in Bereaved Families
This study aims to analyze the grieving process of people who have lost a close first degree relative, understand the impact of death conditions and model a "theory of mourning" in the context of the COVID-19 crisis .
- Trial name
- COVIDAAD (NCT05566366)
- Testing
- Qualitative research interview
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Macular Edema, Central Retinal Vein Occlusion
Ozurdex Versus Ranibizumab Versus Combination for Central Retinal Vein Occlusion
CRVO occurs when the vessels in the back of the eye become blocked. This creates a dangerous condition because the vessels are weak and prone to leakage. This results in the development of macular edema.
- Trial name
- ORION (NCT01827722)
- Testing
- Ozurdex, Ranibizumab, Combination Ozurdex with Ranibizumab PRN
- Where
- 5 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Valley Retina Institute
Tooth Loss
Ridge Preservation With Putty Allografts
The study will consist of randomized controlled clinical study trial comparing the results of a demineralized putty allorgraft versus a combined mineralized/demineralized putty allograft in approximately 30 patients, 15 per…
- Trial name
- NCT03956251
- Testing
- Combined Mineralized/Demineralized Putty Allograft, Demineralized Putty Allograft
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Urine VOCs From DKD and Nephrotic Syndrome Pateints
The Biosensor Using the Target Urine VOCs for Detecting DKD Diabetic Kidney Disease
Volatile organic compounds (VOCs) are easily evaporated substances produced by pathophysiologic metabolism and have been utilized in research as potential new biomarkers for differentiating various diseases, acting as the odor…
- Trial name
- VOCs in DKD (NCT07137351)
- Testing
- The Biosensor Using the Target Urine Volatile Organic Compounds
- Where
- Thailand
- Volunteers
- healthy volunteers welcome
- Sponsor
- Suranaree University of Technology
Voice Disorders
Multimodal Analysis of Structural Voice Disorders Based on Speech and Stroboscopic Laryngoscope Video
This study intends to collect clinical data such as strobary laryngoscope images and vowel audio data of patients with structural voice disorders and healthy individuals, and to establish a multimodal voice disorder diagnosis…
- Trial name
- NCT05348031
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Hepatocellular Carcinoma
Hepatectomy Combined With Camrelizumab and Apatinib in CNLC Stage IIIb HCC
This study intends to prospectively enroll CNLC stage IIIb HCC cases with extrahepatic metastasis and intrahepatic lesions that are expected to be radical resected in several domestic clinical centers, and observe the OS and ORR…
- Trial name
- NCT05062837
- Testing
- Hepatectomy Combined With Camrelizumab and Apatinib
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Dermatology/Skin - Other
Photograph Quality Rating Scale Study ("PQRS Study")
Advances in smart phone-based photography (both quality and image transmission) offer the potential to greatly improve access to pediatric dermatologists.
- Trial name
- PQRS (NCT03246945)
- Testing
- Instructions on taking photographs provided, see methods
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Non-celiac Gluten Sensitivity, Wheat Hypersensitivity
Wheat Bread Study: Comparison of the Tolerance of Different Wheat Breads
This study aims to assess the differences in tolerability of differently manufactured wheat breads in a target group of individuals with suspected wheat sensitivity.
- Trial name
- NCT06152445
- Testing
- Wheat bread
- Where
- 2 sites in Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
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