Clinical trials: Condition
Colorectal Cancer, Adenomatous Colorectal Polyps
Selenium for Prevention of Adenomatous Colorectal Polyps
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. Selenium may be effective in preventing the recurrence of adenomatous colorectal polyps.
- Conditions
- Colorectal Cancer, Adenomatous Colorectal Polyps, Precancerous Condition
- Trial name
- NCT00078897
- Testing
- Selenium
- Where
- 7 sites in United States
- Volunteers
- 1,621 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Physical Condition, Minor Psychological Component
HEALTH AND EXERCISE IN THE DEFENSE FORCES
The most important goal is to create a cost-effective, stimulating model for improving the employee's quality of life, work ability, and job satisfaction in the military operating environment.
- Trial name
- NCT03539679
- Testing
- Encouraging physical activity.
- Where
- Finland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
No Disease State or Condition
Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 on Gingival Mucosal Tissue in Normal Volunteers
The purpose of this study is to determine if the topical application to gingival tissue of the combination of benzocaine and tetracaine has a longer duration of local anesthetic activity than benzocaine alone.
- Trial name
- NCT03233737
- Testing
- One spray CTY-5339-A, One spray CTY-5339-CB, One spray CTY-5339-P
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cetylite Industries
Healthy Infants, Infants With an Inflammatory Condition
Novel Isotope Dilution Technique to Assess Vitamin A Status
Background: There is no reliable method for vitamin A (VA) assessment for infants and young children. Serum VA concentration is not an authenticate indicator of VA status, while existing deuterium- VA isotope dilution methods to…
- Trial name
- NCT03000543
- Testing
- Vaccine
- Where
- 2 sites in Bangladesh
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
no Condition, Basic Science
Effects of Prazosin on the Attention-Enhancing Effects of Nicotine
To test whether specific aspects of the attention-enhancing effects of nicotine may be mediated by down-stream activation of alpha1 adrenoceptors, the interaction of nicotine and the alpha1 adrenergic antagonist prazosin on…
- Trial name
- NCT03416569
- Testing
- Nicotine, Prazosin, Nicotine + Prazosin
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Genetic Condition
Effectiveness of PGT-A: IVF Versus ICSI
The investigators want to investigate if the use of conventional in vitro fertilization (IVF) can generate more euploid embryos as compared to intracytoplasmic sperm injection (ICSI).
- Trial name
- NCT03708991
- Testing
- IVF combined with PGT-A, ICSI combined with PGT-A
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Conditions Influencing Health Status
Clinical Applications of a Smart Physical Examination System for the Health Management in Elderly
Aging usually results in a decline in motor function. However, the elderly tend to refuse the regular health examination because of travel issues or lack of self-health awareness.
- Trial name
- NCT03858660
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Work-Related Condition
Working Shift Organization, Caregivers' Satisfaction and Quality of Life at Work, and Performance.
This is a prospective, non-randomized, multicenter, observational national study, involving centers with different working shift organizations.
- Trial name
- IOTA-REA (NCT03875521)
- Where
- France
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
All Conditions of Integrative Medicine Clinic Patients
Registry for Integrative Medicine Interventions Effectiveness
This registry will perform prospective surveillance of participants attending collaborating Integrative Medicine clinic sites for clinical services.
- Trial name
- PRIMIER (NCT01754038)
- Where
- 14 sites in United States
- Volunteers
- 5,069 people, healthy volunteers welcome
- Sponsor
- BraveNet
Sleep Control Condition, Insomnia Symptoms Induction Condition
Pain Sensitization and Habituation in a Model of Experimentally-induced Insomnia Symptoms
The main purpose of this study is to learn about the effects of repeated exposure to sleep disruption (3 cycles of sleep disruption, each consisting of three days in a row where sleep is shortened and disrupted, followed by a…
- Trial name
- NCT02484742
- Testing
- Insomnia symptom induction
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Neck; Anomaly, Muscle Weakness
Attentional Focus Influence During Cranio-Cervical Flexion Test
The purpose of this study is to termine if a different attentional focus would alter the motor control in cervical muscles during the cranio-cervical test.
- Conditions
- Neck; Anomaly, Muscle Weakness, Muscle Weakness Condition
- Trial name
- NCT03567122
- Testing
- Internal Focus of Attention, External Focus of Attention, Control
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
There is no Focus on Any Specific Condition
Antegrade Versus Retrograde IV for Blood Draws
The purpose of this study is to compare success rates of antegrade and retrograde intravenous (IV) catheters in their ability to aspirate 20 milliliter blood sample within a 2 minute time frame, 3 hours after initial insertion.
- Trial name
- NCT03533777
- Testing
- Peripheral intravenous catheter placement, Blood draw, Peripheral intravenous catheter
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Shift-Work Related Sleep Disturbance, Metabolic Syndrome
Health Effect of Canola Oil Consumption in Shift Workers
Shift work is associated with a higher risk of the development of cardiometabolic syndrome (CMtS) than in people working only during the day.
- Conditions
- Shift-Work Related Sleep Disturbance, Metabolic Syndrome, Diet Modification, Work-Related Condition
- Trial name
- NCT03977558
- Testing
- Intervention group, Control group
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Physiological Conditions
Microcirculation & ASICs
Pressure ulcers are a common and costly problem. Advancing the understanding regarding the basic pathophysiological mechanisms mediating the development of pressure ulcers will allow for better delineation of populations at risk.
- Trial name
- NCT01246180
- Testing
- Diclofenac, Amiloride
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Postoperative Nausea and Vomiting, Respiratory Conditions Due to Other External Agents
A Study to Compare Neostigmine vs Sugammadex in Length of PACU Stay in Patients Undergoing Sleeve Gastrectomy Surgery
The investigators will track bariatric patients who received sugammadex versus neostigmine in the post anesthesia care unit until discharge and assess their length of stay and possible nausea / vomiting / hypoxia episodes.
- Trial name
- NCT03276026
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Musculoskeletal Diseases or Conditions
Musculoskeletal Pathologies of the Upper Extremity in Surgical Device Mechanics
Work-related upper extremity musculoskeletal disorders (WRUEMSDs) have shown to be related to many occupational situations and specific industries.
- Trial name
- PEIN (NCT03014128)
- Testing
- Clinical examination and data processing of questionnaires
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- District Hospital, Tuttlingen
Condition
"We Walk": Impact of Exercise Dose on Health Outcomes Among Women Ages 60-75
The overall goal is to determine whether any energy expenditure compensation in response to 16 weeks of aerobic exercise at a higher-dose is greater compared to a lower-dose intervention in older women, and to begin to…
- Trial name
- WW (NCT01722136)
- Testing
- Low Dosage, High Dosage
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
CORE Condition, Healthy Lifestyle Psychoeducational Program
Efficacy and Effectiveness of a Self-applied Online Program to Promote Resilience and Coping Skills in College Students
This study aims to evaluate the effectiveness and efficiency of this intervention protocol applied to three populations of Spanish-speaking university students (Spain, Argentina and Mexico).
- Conditions
- CORE Condition, Healthy Lifestyle Psychoeducational Program, Waiting List Control
- Trial name
- NCT03903978
- Testing
- Cognitive Behavioral Therapy, Healthy lifestyle
- Where
- 5 sites in Argentina, Mexico and 1 more
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I
Normal Healthy Volunteers Without Chronic Medical Conditions
Quantification of Myocardial Blood Flow by Positron Emission Tomography in Healthy Volunteers
To establish quantitative values of myocardial blood flow (MBF) in normal, healthy volunteers .
- Trial name
- PET Normals (NCT03895554)
- Testing
- cardiac PET stress test
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Cervical Cancer, Precancerous Condition
Vaccine To Prevent Cervical Intraepithelial Neoplasia or Cervical Cancer in Younger Healthy Participants
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer form forming, growing, or coming back. Vaccines may help the body build an effective immune response against human papillomavirus and may be effective in…
- Trial name
- NCT00128661
- Testing
- human papillomavirus 16/18 L1 virus-like particle/AS04 vaccine, hepatitis A inactivated virus vaccine
- Where
- Costa Rica
- Volunteers
- 7,466 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline