Clinical trials: Condition
Metabolic Syndrome
Acute Effects of Oral Carbohydrate and Fat Loads on Systemic Microvascular Endothelial Function in Healthy Individuals.
The present study was designed to evaluate vascular endothelial dysfunction resulting from the oral ingestion of high loads of sugar and fat meals in healthy individuals.
- Trial name
- NCT03515460
- Testing
- sugar oral load, fat oral load, sugar and fat oral load
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Asphyxia Neonatorum, Morbidity;Newborn
Effects of Probiotic Mixture Supplementation and Evaluation of Intestinal Mucosal Tolerance and Gut Microbiome in Newborns With Perinatal Asphyxia Receiving Hypothermic Treatment
The VISNAT trial is a PILOT STUDY due to absence of previous evidences in literature on using probiotic in newborns with perinatal asphyxia.
- Trial name
- VISNAT (NCT04145713)
- Testing
- Probiotic mixture
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Tracheoesopharyngeal Fistula, Bronchoesophageal Fistula
Adipose Derived SVF for Aero-digestive & Enterocutaneous Fistulae
Determine safety and feasibility of using institutionally prepared autologous, uncultured SVF on patients with aerodigestive and enterocutaneous fistulae secondary to malignancy, trauma or surgery.
- Conditions
- Tracheoesopharyngeal Fistula, Bronchoesophageal Fistula, Tracheoesophageal Fistula
- Trial name
- NCT03792360
- Testing
- SVF (Stromal Vascular Fraction)
- Sponsor
- Mayo Clinic
Radiation Therapy
EVALUATION OF THE BENEFITS OF SOPHROLOGY FOR PATIENTS UNDERGOING RADIOTHERAPY
Anxiety is a common symptom among patients undergoing radiation therapy, stemming from their cancer diagnosis, anticipation of side effects, and the specific challenges associated with the treatment sessions.
- Trial name
- SORA-RT (NCT07652060)
- Testing
- Sophrology
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Clinique Pasteur Lanroze
Burns, Trauma
Microcirculatory Assessment in Patients With Trauma and Severe Burns
Predict the development of multiple organ failure in patients with trauma and severe burns.
- Trial name
- NCT01922960
- Testing
- micro-imaging
- Where
- United States
- Sponsor
- University of South Alabama
Surgical Stress Response, Stress Physiological
Feasibility of Breathwork Intervention With Older Adults After Knee Surgery
Postoperative complications after surgical procedures, including following total knee arthroplasty (TKA), have a negative impact on the health and well-being of surgical patients.
- Conditions
- Surgical Stress Response, Stress Physiological, Stress Physiology, Stress Psychological
- Trial name
- NCT07464860
- Testing
- A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Obsessive Compulsive Disorder
Efficacy of Adding Topiramate to Current Treatment in Refractory Obsessive Compulsive Disorder (OCD)
SRI's are considered first-line treatments for OCD, however many patients continue to have significant symptoms despite an adequate trial of an SRI.
- Trial name
- NCT00182520
- Testing
- Topiramate
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- McMaster University
Cardiac Sarcoidosis, Sarcoidosis of the Heart
Exosome-based Omic Signatures of Disease Activity in Cardiac Sarcoidosis (EXODACS)
The purpose of this study is to develop a prospective cohort of patients with and without cardiac sarcoidosis as well as active and inactive disease to develop a prospective biobank from which exosome analysis of peripheral blood…
- Conditions
- Cardiac Sarcoidosis, Sarcoidosis of the Heart, Sarcoidosis With Myocarditis, Sarcoidosis, Cardiac
- Trial name
- EXODACS (NCT07604220)
- Testing
- Exosome Analysis
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Mayo Clinic
Chondromalacia Patellae
Neuroprolotherapy With Physical Therapy for Treatment of Patellar Chondromalacia
Patellar chondromalacia is the degeneration of articular cartilage located on the posterior face of the patella and may suggest the onset of an osteoarthrosis.
- Trial name
- NCT03515720
- Testing
- Prolotherapy
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Instituto Mexicano del Seguro Social
Pancreatic Cancer
Early Increase in Blood Flow (EIBS) in the Duodenum in Patients With Pancreatic Cancer
Pancreatic cancer is the fourth leading cause of cancer death in the United States and is associated with a poor prognosis. The average life expectancy after diagnosis is approximately 5 to 8 months.
- Trial name
- NCT01015820
- Testing
- EGD with EUS, 4D-ELF
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Mayo Clinic
Renal Cell Carcinoma, Adrenal Carcinoma
VETC, Prognostic and Predictive Value in Renal Cell Carcinoma and Adrenal Carcinoma
Metastasis is the main cause of death in cancer patients and often epithelial-to-mesenchymal transition (EMT) is advocated as the basic mechanism.
- Trial name
- NCT04666220
- Testing
- VETC evaluation
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Humanitas Clinical and Research Center
Myelofibrosis
Allogeneic Stem Cell Transplantation for Myelofibrosis and Myelodysplastic Syndrome
The goal of this clinical research study is to learn if using a combination of fludarabine, busulfan, and antithymocyte globulin (ATG) can help to control myelofibrosis or myelodysplastic syndrome in patients receiving a bone…
- Trial name
- NCT00475020
- Testing
- Busulfan, Fludarabine, Thymoglobulin (ATG)
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- M.D. Anderson Cancer Center
Obstructive Sleep Apnea (OSA)
Oral Dynamic Propulsion Appliance in Treatment of Patients With Obstructive Sleeping Apnea
Obstructive Sleep Apnea (OSA) is one of the most prevalent sleep disorders, affecting nearly one billion people worldwide. It is characterized by repeated episodes of complete (apnea) or partial (hypopnea) obstruction of the…
- Trial name
- NCT07414420
- Testing
- dynamic propulsion oral appliance treatment (DPOA), elastic mandibular advancement appliance treatment
- Where
- Serbia
- Volunteers
- 40 people
- Sponsor
- University of Belgrade
Myopia
Identification of Genomic Loci Determining Susceptibility to the Development of High Myopia
Compelling evidence of genetic components in high myopia has been put forward by several studies. Twin cohorts, familial linkage studies and population studies has described at least 10 loci containing genes involved in the…
- Trial name
- ASSOMYP (NCT02583620)
- Testing
- blood sample
- Where
- 4 sites in France
- Volunteers
- 553 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Diabetes, Diabetes Mellitus, Type 2
A Clinical Trial Investigating the Comparison of Three Different Concentrations of NN9535 in Healthy Male Subjects
This trial is conducted in Europe. The aim of this clinical trial is to investigate whether differences exist between three different concentrations of the drug, NN9535, administered in healthy male subjects in equal doses.
- Trial name
- NCT00813020
- Testing
- semaglutide
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Novo Nordisk A/S
Acute Lymphoblastic Leukemia
Adaptive Variable-Resistance Training in Pediatric Survivors of Acute Lymphoblastic Leukemia
This study was designed to investigate the effect of eight weeks of adaptive variable-resistance training (Adaptive-VRT) on chemotherapy-induced sarcopenia, fatigue, and functional restrictions in a convenience sample of…
- Trial name
- NCT06338020
- Testing
- Adaptive variable-resistance training, Standard physical therapy
- Where
- Saudi Arabia
- Volunteers
- 62 people
- Sponsor
- Cairo University
Leukemia
Study of Vosaroxin and Decitabine in Older Patients With Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome
The goal of this clinical research study is to learn if the combination of vosaroxin and decitabine can help to control AML or MDS. The safety of these drugs will also be studied.
- Trial name
- NCT01893320
- Testing
- Vosaroxin, Decitabine
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- M.D. Anderson Cancer Center
Nephrotic Syndrome
The Efficacy of Huaiqihuang Granule in Children With Primary Nephrotic Syndrome
This is a multisite, open-label, prospective and registered study designed to evaluate the efficacy and safety of Huai-Qi-Huang granule in children with primary nephrotic syndrome.
- Trial name
- NCT03332420
- Where
- 17 sites in China
- Volunteers
- 1,507 people
- Sponsor
- Qidong Gaitianli Medicines Co., Ltd
Pain
Self-administered Intravaginal 2% Lidocaine Gel Prior to Intrauterine Device Insertion in Nulliparous Women
This study is designed to evaluate if self-inserted intravaginal 2% lidocaine gel is effective at decreasing pain during intrauterine device insertion in nulliparous women.
- Trial name
- LIVIIN (NCT01534520)
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Stroke
Neurobiological Principles Applied to the Rehabilitation of Stroke Patients
The purpose of this study is to use (Transcranial Magnetic Stimulation) TMS or drugs to improve learning of movement skills and the adaptation processes in patients after stroke.
- Trial name
- NCT00715520
- Testing
- Transcranial Magnetic Stimulation (TMS), Carbidopa-Levodopa, Methylphenidate
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Emory University
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