Clinical trials: Conditioning Therapy
Postpartum Depression (PPD)
Evaluating the Effectiveness of an Internet-based Therapy (iCARE) to Treat Symptoms of Postpartum Depression
Postpartum depression (PPD) is a common and serious condition affecting 9.5% of women in high-income countries, and around 8% in Denmark.
- Trial name
- iCARE (NCT07384273)
- Testing
- Internet-based therapy (iCARE) and treatment as usual, Treatment as usual (TAU)
- Where
- Denmark
- Volunteers
- 352 people
- Sponsor
- University of Southern Denmark
Stress Disorders, Post-Traumatic, Schizophrenia
Cognitive Behavioral Therapy for Post-Traumatic Stress Disorder in Individuals With Severe Mental Illness
This study will develop a cognitive behavioral therapy (CBT) program to treat symptoms of post-traumatic stress disorder (PTSD) in people with severe mental illnesses who are treated within community mental health systems.
- Trial name
- NCT00078741
- Testing
- Cognitive Behavioral Therapy (CBT)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Medical University of South Carolina
Major Depressive Disorder
Efficacy of Adjunctive Exercise for the Behavioral Treatment of Major Depression
Major depressive disorder (MDD) is the leading cause of disability in the developed world and is associated with lost productivity, increased health care utilization, and mortality.
- Trial name
- NCT02176408
- Testing
- Behavioral Activation, Exercise Intervention, Stretching Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Boston University Charles River Campus
Recurrent Plasma Cell Myeloma
Reduce Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed Multiple Myeloma
This phase II trial studies how well a reduced intensity conditioning regimen after donor stem cell transplant works in treating patients with multiple myeloma that has come back (relapsed).
- Trial name
- NCT04205240
- Testing
- Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Daratumumab
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Srinivas Devarakonda
Schizophrenia, Schizoaffective Disorder
Cognitive-Behavioral Therapy in Veterans With Schizophrenia
This is a study comparing the benefits of two types of individual psychotherapy (cognitive-behavioral therapy for psychosis and supportive therapy) in symptomatic Veteran outpatients diagnosed with schizophrenia or…
- Trial name
- NCT00688259
- Testing
- Supportive Therapy (ST), Cognitive Behavioral Therapy for Psychosis (CBTp)
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- VA Office of Research and Development
Chronic Pain, Opiate Dependence
Cognitive-Behavioral Therapy for Pain and Opioid Dependence in Methadone Maintenance Treatment
This study involves the comparison of two treatment approaches for patients with chronic pain who are entering methadone maintenance treatment (MMT) for opioid addiction: (a) an integrated counseling that addresses both chronic…
- Trial name
- NCT01334580
- Testing
- Cognitive-Behavioral Therapy for Pain and Opioid Dependence, Methadone Drug Counseling
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Yale University
Myotonic Dystrophy Type 1
Observational Prolonged Trial in Myotonic Dystrophy Type 1
Myotonic dystrophy type1 (DM1) is a rare, inherited, chronic progressive disease as well as an autosomal dominant multisystemic disorder.
- Trial name
- OPTIMISTIC (NCT02118779)
- Testing
- Behavioural change intervention
- Where
- 4 sites in France, Germany and 2 more
- Volunteers
- 255 people
- Sponsor
- Radboud University Medical Center
Obstructive Sleep Apnea, Comorbid Insomnia and Sleep Apnea
Does the Timing of Insomnia Therapy (CBT-i) Impact the Usage and Compliance of Upper Airway Stimulation (UAS) Treatment of Obstructive Sleep Apnea (OSA)
Obstructive sleep apnea, or OSA, affects over 1 billion adults worldwide. OSA is one of many sleep disorders. Individuals can suffer from more than one sleep disorder at a time.
- Conditions
- Obstructive Sleep Apnea, Comorbid Insomnia and Sleep Apnea, Insomnia
- Trial name
- CBT-i and UAS (NCT07838870)
- Testing
- Digital Cognitive Behavioral Therapy (CBT-i)-COAST
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Thomas Kaffenberger
Depression, Anxiety
TODAY! A Mobile App Study
The aim of this study is to conduct a small randomized controlled trial (RCT) for a 10-week mobile phone intervention using principles of Cognitive Behavior Therapy to target general and minority stressors and treat anxiety and…
- Trial name
- TODAY! (NCT03534167)
- Testing
- TODAY! App and Coaching
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Breast Cancer, Cervical Cancer
Cultivando la Salud: A Breast and Cervical Cancer Screening Promotion Program for Low-Income Puerto Rican Women
The overall goal of this education program is to increase breast and cervical cancer screening in low-income women in Puerto Rico through implementation of an evidence-based educational program that addresses both health…
- Trial name
- CLS (NCT04617236)
- Testing
- Cultivando La Salud
- Where
- Puerto Rico
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Multiple Sclerosis
Factorial Optimization Trial to Test Cognitive Behavioral Therapy Components for Multiple Sclerosis Fatigue
This randomized controlled factorial trial will examine whether and how relaxation training, behavioral activation, and cognitive therapy improve fatigue and functioning in fatigued adults living with multiple sclerosis.
- Trial name
- NCT06809192
- Testing
- 4-session Relaxation Training, 4-session Behavioral Activation, 4-session Cognitive Therapy
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of Washington
Mental Disorder, Mental Stress
Virtual Agents-based Digital Interventions to Improve Health
KANOPEE is a free smartphone application providing screening, follow-up tools and autonomous digital interventions to lower psycho-social stress and its repercussions on sleep and behaviors in the general population.
- Conditions
- Mental Disorder, Mental Stress, Insomnia, Depression
- Trial name
- KANOPEE (NCT05074901)
- Testing
- digital behavioral intervention
- Where
- France
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Autism Spectrum Disorder, Autism
Investigation of Mechanisms of Action in Superpower Glass
The following study aims to understand the mechanism of action at work in a novel artificial intelligence (AI) tool that runs on Google Glass through an Android app to deliver social emotion cues to children with autism during…
- Trial name
- NCT04049981
- Testing
- Superpower Glass
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Stanford University
Spinal Cord Injury (SCI)
Interdisciplinary Value-based Cognitive Behavioral Treatment for People With Traumatic Spinal Cord Injury
The goal of this clinical trial is to address the critical need for effective interventions by developing and testing an interdisciplinary values-based cognitive behavioral therapy (V-CBT) program for individuals with spinal cord…
- Trial name
- VALIANT (NCT06599632)
- Testing
- Values-based Cognitive Behavioral Therapy (V-CBT)
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- University of Southern Denmark
Tinnitus
Guided ICBT for Adults With Tinnitus in Canada: A Randomized Controlled Trial
The goal of this randomized controlled trial is to learn if guided Internet-delivered Cognitive Behavioural Therapy can treat tinnitus-related distress and its associated comorbidities such as anxiety, depression, insomnia, and…
- Trial name
- NCT06584175
- Testing
- Internet Delivered Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- Western University, Canada
Depression, Anxiety
Project 2: Optimizing Engagement and Outcomes in STAND Digital Therapy
The goal is to optimize peer coaching in order to optimize engagement and outcomes in digital therapy. The unmet mental health needs of community college students are staggering and a growing body of research demonstrates that…
- Trial name
- P2 (NCT05908565)
- Testing
- Demographic Matching, Supervision Intensity
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of California, Los Angeles
Posttraumatic Stress Disorder
Impact of Cognitive Behavioral Therapy on PTSD-CVD Link
This is a pilot randomized controlled trial to assess the impact of a first-line treatment for posttraumatic stress disorder (PTSD) (Cognitive Processing Therapy; CPT) versus waitlist control on mechanisms of cardiovascular…
- Trial name
- NCT06429293
- Testing
- Cognitive processing therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Fibromyalgia
Pain Neuroscience Education, Conditioned Pain Modulation and Emotional Processes in Fibromyalgia
Chronic pain represents a significant public health concern worldwide and is a primary reason why patients seek specialized medical care.
- Trial name
- NEUROPAINFIB (NCT07055971)
- Testing
- Experimental: Pain Neuoescience Education Group, Active Comparator: Biomedical Education Group
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Universidad de Granada
Aortic Valve Stenosis
Home-Based Exercise Program For Recovery After Transcatheter Aortic Valve Replacement
Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure for older adults with severe symptomatic aortic stenosis who are considered high risk for surgical aortic valve replacement.
- Trial name
- REHAB-TAVR (NCT02805309)
- Testing
- Exercise, Cognitive behavioral interventions, Attention control education program
- Where
- 3 sites in United States
- Volunteers
- 64 people
- Sponsor
- Brigham and Women's Hospital
Insulin Resistance, Depression
Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes
The investigators are doing this study to learn more about how to prevent type 2 diabetes in teenage girls. The purpose of this study is to find out if taking part in a cognitive-behavioral therapy group, exercise training group…
- Conditions
- Insulin Resistance, Depression, Depressive Disorder, Mood Disorders
- Trial name
- CBTeX (NCT05543083)
- Testing
- Cognitive-Behavioral Therapy followed by Exercise Training, Exercise Training followed by Cognitive-Behavioral Therapy, Cognitive-Behavioral Therapy Only
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Colorado State University