Clinical trials: Conditions
Palatal Wound
Effects of Topical Hyaluronic Acid Gel on Postoperative Pain and Wound Healing
This clinical study aims to investigate the impact of a topical hyaluronic acid (HA) gel on postoperative pain and wound healing at palatal donor sites in patients undergoing mucogingival procedures involving a de-epithelialized…
- Trial name
- NCT05821725
- Testing
- Hyaluronic acid, Control
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Pulp Necroses
Post Operative Pain Assessment After Pulpectomy of Primary Molars With Two Different Rotary Systems
Evaluation of post operative pain after pulpectomy procedures for primary molars with irreversible pulp damage and without periapical radulicency using two different systems (One shape file ( ratation movemont) and wave one gold…
- Trial name
- NCT05057325
- Testing
- Pulpectomy using single file system ( One Shape file), Pulpectomy using single file system ( WaveOne Gold file)
- Where
- Egypt
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Minia University
Obesity & Overweight
Front-of-package Warning Labels for Sugar Content in Sugar-sweetened Beverages
The goal of this online randomized trial is to examine the effectiveness of Front-of-package (FOP) warning labels for added sugar content on the intent-to-purchases of SSBs in an affluent Asian setting.
- Trial name
- NCT07570576
- Testing
- UK-style traffic light labels, Chile-style octagonal labels, text warning labels
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Musculoskeletal Pain, Neck Pain
Musculoskeletal Pain of Neck and Shoulder Area in Female Office Workers: Relations Between Muscle Tone, Stiffness, Pain-pressure Threshold, Self-reported Pain Intensity and Physical Activity.
The objective of this study is to determine the differences between neck and shoulder region skeletal muscle tone, stifness, pain-pressure threshold, self-reported pain intensity and physical activity in female office workers.
- Conditions
- Musculoskeletal Pain, Neck Pain, Shoulder Pain
- Trial name
- NCT04254276
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Orthognathic Surgical Procedures
Mandibular Medial Osteotomy Modifications and Postoperative Stability
This study aims to compare the effects of the Hunsuck and Posnick modifications of medial mandibular osteotomy on postoperative skeletal stability and relapse in patients undergoing orthognathic surgery.
- Trial name
- NCT07788976
- Testing
- sagittal split osteotomy, Hunsuck Modification of Medial Mandibular Osteotomy, Posnick Modification Group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Menopause Syndrome, Menopause Surgical
Paroxetine Versus Placebo for Vasomotor Symptom Management in Surgical Menopause
evaluate the efficacy of paroxetine in the management of vasomotor symptoms in patients with surgical menopause, in order to seek an alternative therapy to hormone therapy, which is associated with proinflammatory and…
- Conditions
- Menopause Syndrome, Menopause Surgical, Hot Flashes
- Trial name
- MENOXTINA (NCT06763484)
- Testing
- Paroxetine
- Where
- Honduras
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Pregnancy, Labor Pain
Association Between Fluid Administration, Oxytocin Administration, and Fetal Heart Rate Changes
Fetal heart rate patterns are an important parameter in the diagnosis of non-reassuring fetal status. Combined-spinal epidural analgesia is a method of initiating labor analgesia used by approximately 90% of the parturients at…
- Trial name
- NCT02121184
- Testing
- Routine oxytocin, Half-dose oxytocin
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Dry Eye, Eye Fatigue
A Randomized Controlled Trial to Evaluate the Safety and Efficacy of an Oral Supplement in Supporting Vision and Eye Health
This is a 4-week virtual randomized, triple-blinded, placebo-controlled clinical trial evaluating the safety and efficacy of Eye Empower, an oral supplement, in adults aged 45 or older experiencing dry eyes, irritation, and…
- Trial name
- NCT07123584
- Testing
- Eye Empower
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bio Nature Health
Chronic Pain
Study To Assess Safety, Tolerability And PK Of ATB-346 In Healthy Subjects
A double-blind, placebo-controlled, phase I study to assess safety, tolerability and pharmacokinetics of single/multiple ascending doses of atb-346 orally administered in healthy male and female subjects.
- Trial name
- NCT03220633
- Testing
- ATB-346
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Antibe Therapeutics Inc.
Genetics, Obesity
Inherited and Environmental Risks Acting on Body Weight
The goal of this research is to investigate genetic and environmental factors that contribute to obesity through brain inflammation.
- Trial name
- INTERACT (NCT07430852)
- Testing
- Diet modification
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Washington
Analgesia
Comparison of Standard Epidural and Dural Puncture Epidural Analgesia in Open Gynecological Surgery Techniques
The aim of this study is to compare the effectiveness of standard epidural and dural puncture epidural analgesia techniques used under NOL guidance.
- Trial name
- NCT05408052
- Testing
- Dural Puncture Epidural (DPE), Standart Epidural
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Overweight
Time to Eat Study - Pilot
The goals of this pilot study is to evaluate the safety and feasibility of time restricted feeding in an older adult population.
- Trial name
- NCT03590847
- Testing
- Intermittent Fasting
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Florida
Dietary Change, Obesity & Overweight
Dietary Peanuts and Nutrition-Related Outcomes
This study will look at how eating peanuts every day might affect participants weight, how healthy their diet is, and how they feel when eating.
- Conditions
- Dietary Change, Obesity & Overweight, Food Acceptance
- Trial name
- NCT07244458
- Testing
- Peanuts, Dual-energy X-ray absorptiometry (DEXA) scans
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ian J. Neeland, MD
Obesity
Phone Versus Clinical Approach to Weight Loss
Weight loss and maintenance continues to be problematic for individuals who are overweight or obese. State-of-the-art treatment generally involves a behavioral weight loss clinic that emphasizes nutrition, physical activity, and…
- Trial name
- NCT01095458
- Testing
- Phone versus Clinic Weight Management Programs
- Where
- United States
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Aspiration Vomitus
Granisetron Versus Metoclopramide Effects on Gastric Volume by Sonographic Assessment on Patients Undergoing Caesarean Section.
Ultrasound assessment of the effect of metoclopramide versus granisetron on gastric volume in patients undergoing caesarean section study
- Trial name
- NCT04290026
- Testing
- metoclopramide versus granisetron
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pharmacokinetics, Adult
Evaluation of a Novel PET Radioligand to Image OGA
Background: O-GlcNAcase (OGA) is a brain enzyme. It may play a role in brain disorders like Alzheimer s disease. Researchers want to see if a new drug can be used with positron emission tomography (PET) scans to show OGA better.
- Trial name
- NCT03632226
- Testing
- 18F-OGA-1
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Chronic Kidney Failure, Chronic Kidney Diseases
Physical Impairments in Children With Chronic Renal Failure
When the literature is examined, it is seen that the extent to which cough strength, grip strength, physical activity level and quality of life levels are affected in children with chronic kidney failure compared to healthy…
- Trial name
- NCT06981585
- Testing
- Physical Evaluations of Patients with Chronic Kidney Failure, Physical Evaluations of Healthy Children
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Cough, Upper Respiratory Tract Infections
Effect of Over-the-counter NSAIDS on Cough Reflex Sensitivity in Patients with Upper Respiratory Tract Infections
The goal of this mechanism of disease study is to investigate the effect of flurbiprofen, a non-steroidal anti-inflammatory drug (NSAID), on the cough hypersensitivity associated with upper respiratory tract infections (URTI).
- Trial name
- NCT05955885
- Testing
- Flurbiprofen Oral Lozenge, Difflam, Flurbiprofen 8.75 MG
- Where
- Australia
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Facial Asymmetry, Reconstructive Surgical Procedures
Exploring Optimal Photographic Parameters for Standardized Facial Aesthetics Analysis
The main objective of this research is to identify the focal length that allows the most accurate and reproducible 2D assessment of facial aesthetics, without introducing significant distortion.
- Conditions
- Facial Asymmetry, Reconstructive Surgical Procedures, Facial Morphology
- Trial name
- OPTIFACE (NCT07052643)
- Testing
- Image and data collection
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hôpital NOVO
Hot Flashes, Menopause
MsFLASH-01: Escitalopram for Menopausal Symptoms in Midlife Women
The purpose of this study is to test whether a medication reduces the number, severity and bothersomeness of menopausal hot flashes. Escitalopram (also called Lexapro®) is a selective serotonin reuptake inhibitor (SSRI).
- Conditions
- Hot Flashes, Menopause, Vasomotor Symptoms
- Trial name
- NCT00894543
- Testing
- Escitalopram
- Where
- 5 sites in United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
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