Clinical trials: Conditions
Healthy Volunteers
A Study Comparing The Amounts of Tafamidis In The Blood With Or Without Food
Each subject will be given tafamidis after either a high fat meal or while fasted. After swallowing tafamidis, tafamidis blood concentrations will be measured periodically for one week.
- Trial name
- NCT02406560
- Testing
- tafamidis
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Multiple Sclerosis
Applications of Nanotechnology in Multiple Sclerosis by Respiratory Samples
Multiple Sclerosis (MS) is a complex multi-factorial disease, with underlying both genetic and environmental factors. Different populations have different susceptibility.
- Trial name
- MS-NANOSE (NCT01206023)
- Testing
- NA-NOSE artificial olfactory system
- Where
- 2 sites in Israel
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Urinary Stone
Etiological Diagnosis of Urinary Stone in Chinese Children
The incidence of nephrolithiasis in children has been reported to increase by approximately 6-10% annually, and the incidence is currently 50 per 100,000 children with high recurrent rate.
- Trial name
- NCT02949323
- Testing
- urinary stone
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Healthy
Levetiracetam 750 mg Tablets Under Fasting Conditions
The objective of this study is to compare the rate and extent of absorption of a test formulation of Levetiracetam and the reference Keppra® administered as a 1 x 750 mg tablet under fasting conditions.
- Trial name
- NCT00849862
- Testing
- Levetiracetam, Keppra®
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Head and Neck Cancer
Prediction of Outcome After Chemoradiotherapy for Head and Neck Cancer Using Functional Imaging and Tumor Biology
Despite uniform histopathological definition the response of locally advanced squamous cell carcinomas of the head and neck (HNSCC) to ionizing radiation differs greatly with locoregional recurrences burdening this patient…
- Trial name
- NCT01829646
- Testing
- functional MRI, Hypoxia gene expression profile., Functional MRI before start of treatment.
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Healthy
Comparison of Bioavailability of Dexketoprofen-Vit B vs Dexketoprofen, in Healthy Subjects, Under Fasting Conditions
Bioavailability comparison study with a cross-over desing, 2x2, open, prospective and longitudinal, at a single dose with two treatments, two periods, two sequences with an elimination (washout) period of 7 days and a number of…
- Trial name
- NCT05027126
- Testing
- Dexketoprofen 25 MG, Fixed dose Dexketoprofen-Vitamin B Complex
- Where
- Mexico
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Gingival Bleeding, Prosthesis Failure, Dental
Comparison of Effectiveness of Gingival Displacement Using Retraction Cord and Aluminum Chloride Gel
This study aims to compare the horizontal gingival displacement by using a retraction cord and aluminum chloride gel, and also to determine the time taken for placement and hemorrhage after the procedure by using a retraction…
- Conditions
- Gingival Bleeding, Prosthesis Failure, Dental, Tissue Injury
- Trial name
- NCT07255976
- Testing
- knitted cotton retraction cord, aluminum chloride gel
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Chronic Obstructive Pulmonary Disease, Bronchial Asthma
Influence of Bag Volume Variation on the Reproducibility of Inert Gas Rebreathing
Non-invasive inert gas rebreathing (IGR) based on the Fick Principle showed promising results in the determination of pulmonary blood flow (PBF).
- Conditions
- Chronic Obstructive Pulmonary Disease, Bronchial Asthma, Restrictive Pulmonary Disease
- Trial name
- NCT01762917
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Low Back Pain After Epidural Steroid Injection, Quality of Life After Epidural Steroid Injection
Statin and Epidural Steroid Injection
The impact of statin use on response to epidural steroid injections remains unknown and may well increase the effect considering the substantial anti-inflammatory properties.
- Trial name
- NCT02162940
- Testing
- Visual analogue score, The SF 36 test
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Anemia, Iron Deficiencies
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CTX001 in Healthy Adults.
This study is testing CTX001 for certain conditions where the body does not have enough available iron or has difficulty storing or moving iron properly.
- Conditions
- Anemia, Iron Deficiencies, Chronic Kidney Disease
- Trial name
- NCT07577817
- Testing
- CTX001 With and Without Iron, CTX001 With Iron, CTX001 Multiple Dose
- Where
- Australia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cajal Therapeutics Inc.
Vision Disorders
Unmet Needs, Barriers and Facilitators to Vision Services for Children and Adolescents With Special Vision
Children and adolescents with special needs, compared to those with general development, have a much higher incidence of visual impairments (10.5% vs. 0.16%).
- Trial name
- NCT05921240
- Testing
- observational study, no intervention
- Where
- Taiwan
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Pelvic Organ Prolapse
Pectopexy Surgery Without Mesh
it is aimed to examine the effect of laparoscopic pectopexy surgery without mesh on Pelvic Organ Prolapse Measurement (POP-Q) and quality of life of the patient.
- Trial name
- NCT05715489
- Testing
- Comparison of pre and postoperative POP-Q values of the patients, Comparison of pre and postoperative PISQ-12 scores of the patients
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Hepatitis C, Chronic Hepatitis C
Drug Interaction Study to Assess the Effect of Co-Administered Miravirsen and Telaprevir in Healthy Subjects
The purpose of this study is to assess the safety, tolerability, and affect on blood levels of miravirsen and telaprevir when administered together.
- Trial name
- NCT01646489
- Testing
- Miravirsen sodium, Telaprevir
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Santaris Pharma A/S
Delirium, Awakening, Post-Anesthesia Delayed
Validation and Reliability of the Turkish 4AT Scale for Post-Anesthesia Awakening Delirium
Background: Delirium is a common and serious condition in hospitalized patients that often leads to extended hospital stays and increased healthcare costs. Accurate and timely detection is essential for optimal patient outcome.
- Conditions
- Delirium, Awakening, Post-Anesthesia Delayed, Delirium, Postoperative, Nurse's Role
- Trial name
- NCT06187389
- Testing
- 1 Grups
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Overweight, Obesity
Nutrition, Exercise, and Technology for Weight Loss
The purpose of this study is to evaluate whether a social support-enhanced, technology-based, behavioral weight control intervention can improve weight loss over existing best practices.
- Trial name
- NCT02731768
- Testing
- Standard, Social support-enhanced, Fitbit Zip
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Cough
Validation of a Questionnaire to Measure Cough Severity
To design and validate a questionnaire that allows objective assessment of the severity of chronic cough
- Trial name
- NCT06669897
- Testing
- Questionnaire
- Where
- 6 sites in Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Symptomatic Irreversible Pulpitis (SIP), Dental Pain
Intraligamentary vs Inferior Alveolar Nerve Block for Pulpitis: A Randomized Clinical Trial
This multicenter randomized trial compares the clinical effectiveness of intraligamentary injection versus inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis in mandibular molars.
- Conditions
- Symptomatic Irreversible Pulpitis (SIP), Dental Pain, Inferior Alveolar Nerve Block Failure, Local Anesthesia
- Trial name
- NCT07130760
- Testing
- Intraligamentary Injection, Inferior Alveolar Nerve Block
- Where
- 2 sites in Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Aula Dental Avanzada
Korean, Male
The Effect of Education on Decreasing the Prevalence and Severity of Neck and Shoulder Pain
Neck and shoulder pain (NSP) is fairly common among high school students in Korea. Presumably, the high prevalence of NSP in Korean adolescents is a consequence of an inappropriate static position for a prolonged period of time.
- Conditions
- Korean, Male, Adolescents
- Trial name
- NCT01727960
- Testing
- Education and posture correction
- Where
- South Korea
- Volunteers
- 1,302 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Body Weight, Obesity
Meta-analyses of Food Sources of Fructose-Containing Sugars and Obesity
Sugars have been implicated in the epidemics of overweight and obesity. This view is supported by lower quality evidence from ecological observations, animal models, and select human trials.
- Conditions
- Body Weight, Obesity, Overweight, Adiposity
- Trial name
- NCT02558920
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Atrial Fibrillation, Catheter Ablation
Post-Ablation Pericarditis Reduction Study
There has not been a prospective, randomized controlled trial of colchicine to reduce post-AF ablation pericarditis in an era of newer AF ablation techniques.
- Conditions
- Atrial Fibrillation, Catheter Ablation, Pericarditis
- Trial name
- PAPERS (NCT04906720)
- Testing
- Colchicine
- Where
- United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- St. Vincent Cardiovascular Research Institute
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