Clinical trials: Conditions
Post-operative Pain
Genetics of Cytochrome CYP2D6 and Effects of Codeine and Tramadol on Postoperative Pain Management
Codeine is one of the most commonly prescribed opioids in the world. The speed at which our liver metabolizes codeine into morphine depends on an important protein called cytochrome P450 2D6 (CYP2D6).
- Trial name
- CYP2D6 (NCT06723379)
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Fraser Health
Chronic Pain, Musculoskeletal Pain Disorder
Cognitive Bias Modification for Interpretation Individuals With Chronic Musculoskeletal Pain
Cognitive Bias Modification for Interpretation (CBM-I) trains participants to interpret ambiguous information as neutral or benign, rather than interpret it as being related to pain.
- Trial name
- NCT06368362
- Testing
- Benign cognitive bias modification for interpretation, Pain-related cognitive bias modification for interpretation
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Hair Loss/Baldness
Role of Bandage After FUE Hair Transplantation
The aim of this interventional study is to determine the role of bandage on the follicular donor sites on the scalp after FUE hair transplantation.
- Trial name
- NCT05984862
- Testing
- Bandage
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pak Medical and Diagnostic Center
Statin Induced Proteinuria
Statins and the Urinary Proteome
This study aims to investigate whether statines (rosuva- and pravastatin) induce tubular proteinuria.
- Trial name
- NCT00464503
- Testing
- Rosuvastatin-Crestor, Pravastatin-Pravasine
- Where
- Belgium
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Obesity, Weight Loss
Protein Supplementation Intervention on Body Weight
This study is a randomized clinical trail with a parallel design, involving 120 overweight/obese (body-mass index, BMI ≥ 24 kg/m²) participants and 20 normal-weight participants.
- Conditions
- Obesity, Weight Loss, Protein Supplementation
- Trial name
- NCT06989203
- Testing
- General lifestyle and nutritional education, Calorie-restricted balanced diet, semaglutide
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Nocturia, Acupoint
Moxibustion for Nocturia
Nocturia, the interruption of sleep due to nighttime voiding, severely compromises quality of life, emotional health, and overall well-being when occurring twice or more per night.
- Conditions
- Nocturia, Acupoint, Moxibustion, Traditional Chinese Medicine
- Trial name
- NCT07598227
- Testing
- Moxibustion
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Chest Pain, Anxiety
The Effects of Use of Auditory Stimulation Methods on Cardiac Patients' Clinical Outcomes
This study will be used to compare the effects of two auditory stimulation methods on improving vital signs parameters, reducing the severity of chest pain, and improving the sleep quality of cardiac patients.
- Conditions
- Chest Pain, Anxiety, Sleep
- Trial name
- NCT06670027
- Testing
- Family voice, Nature sound
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Damanhour University
Dementia, Traumatic Brain Injury (TBI)
Clinical Characteristics of Dementias That Occur Remotely After Traumatic Brain Injury in Retired Military Personnel
The objective of this study is to measure the frequency and clinical types of mild cognitive impairment (MCI) or dementia that occur among up to 150 military retirees with and without a history of traumatic brain injury (TBI)…
- Conditions
- Dementia, Traumatic Brain Injury (TBI), Mild Cognitive Impairment (MCI), Chronic Traumatic Encephalopathy (CTE)
- Trial name
- NCT01891383
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Multiple Sclerosis
Histaminergic Basis of Fatigue in Multiple Sclerosis
The purpose of this research study is to identify a way to improve the feeling of exhaustion that patients might experience because of Multiple Sclerosis (MS).
- Trial name
- NCT04764383
- Testing
- L-Histidine, Lodosyn
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Anxiety, Surgery
Could Music be an Alternative to Sedation in Patients Treated Total Knee Arthroplasty With Regional Anesthesia?
Background: Anxiety is a common phenomenon in hospitalized patients. In order to reduce it during the surgical procedure, sedatives and anxiolytics are used, which can cause undesirable side effects for patients.
- Conditions
- Anxiety, Surgery, Drug Toxicity, Anesthesia
- Trial name
- NCT03882541
- Testing
- Music therapy, Sedation with midazolam
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de l'Anoia
Overweight, Risk Behavior
Fasting-mimicking Diet and Longevity Diet, Body Composition and Aging
This study was designed as a large, randomized, controlled clinical trial in a heterogeneous population and is aimed at assessing as a primary objective whether the fasting-mimicking diet alone or in combination with the…
- Conditions
- Overweight, Risk Behavior, Obesity
- Trial name
- NCT05698654
- Testing
- Fasting-mimicking diet (FMD), Longevity Diet (LD) + Fasting-mimicking Diet (FMD)
- Where
- Italy
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Fondazione Valter Longo
Color Vision Defects, Color Blindness
Performance of Red Tinted Contact Lenses on Colour Defects
This study aimed to relate and compare the performance of 4 types of red-tinted contact lenses (CL) with the Total Error Score (TES) from the Farnsworth-Munsell 100 Hue test on colour deficient subjects.
- Trial name
- CL (NCT05643222)
- Testing
- red tint contact lenses
- Where
- Malaysia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Healthy
To Assess the Effect of the Special Condition on the Pharmacokinetics and Tolerability of the Esflurbiprofen Topical System (EFTS) in Healthy Volunteers.
This study is a single-center, open-label, single-dose trial performed in a randomized, four-way, change-over design in healthy volunteers.
- Trial name
- NCT06870422
- Testing
- Esflurbiprofen Topical System
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Teikoku Seiyaku Co., Ltd.
Cicatrix, Wound Healing
Genomic Changes Associated With the Use of Intradermal Avotermin (Juvista) in Small Wounds in Healthy Male Subjects
The purpose of this study is to further determine the safety and toleration of intradermal avotermin (Juvista), confirm accelerated healing and investigate genomic expression profiles
- Trial name
- NCT00977951
- Testing
- Intradermal avotermin
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Renovo
Pain
A Study Comparing PF-05089771 TS Capsule To PF-05089771 TS Oral Dispersion In The Fasted State
The primary purpose of this study is to estimate the relative bioavailability and food effect of a PF-05089771 capsule.
- Trial name
- NCT01690351
- Testing
- PF-05089771
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Cervical Cancer
The Effect of Motivational Interviewing Based on the COM-B Model
This research will be conducted to determine the effect of motivational interviewing based on the COM-B model on women's cervical cancer health beliefs and participation in screening.
- Trial name
- NCT06509529
- Testing
- Motivational Interviewing Based on the COM-B Model
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ordu University
Pain, Postoperative Pain
Effect of Neem and NaOCl on Postoperative Pain and Amount of Endotoxins
The aim of this study is to compare the effect of Neem (azadirachta indica) and 2.5% sodium hypochlorite as root canal irrigants on the intensity of post-operative pain and the amount of endotoxins in necrotic teeth.
- Conditions
- Pain, Postoperative Pain, Postoperative Complications, Necrosis
- Trial name
- NCT03312153
- Testing
- Neem, 2.5% sodium hypochlorite
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy
Trandolapril 4 mg Tablet Under Non-Fasting Conditions
The objective of this study is to evaluate the comparative bioavailability between trandolapril 4 mg tablets (test) and Mavik® 4 mg Tablets (reference) after a single-dose in healthy subjects under fed conditions.
- Trial name
- NCT00840073
- Testing
- Trandolapril 4 mg Tablets, Mavik® 4 mg Tablets
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Obesity
AVocAdo Extract to Improve gLycemia in Individuals With Obesity (AVAIL)
This two-arm, double blind, randomized clinical trial will compare the effect of an avocado extract, compared to placebo, on cardiometabolic outcomes in adults with obesity.
- Trial name
- NCT04763473
- Testing
- Avocado extract
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
HIV Infections, Sexually Transmitted Diseases
HIV and STD Prevention for High-Risk, Inner-City, African American Youth
This study will evaluate the joint and separate effectiveness of two HIV/STD prevention programs in providing protection against acquiring STDs and maintaining safer sex behavior.
- Trial name
- NCT00353405
- Testing
- Social Skills Training, Mass media, Control
- Where
- 4 sites in United States
- Volunteers
- 1,650 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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