Clinical trials: Conduct
Substance Use Disorder, Alcohol Use Disorder
Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP
Background: People who will participate in research studies need to undergo proper screening, evaluation, and assessment (SEA). SEA helps keep those who participate in studies safe. It also helps ensure accurate study results.
- Trial name
- NCT06552741
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Risk Reduction
HIV Prevention and Trauma Treatment in Men Who Have Sex With Men and Who Have a History of Sexual Abuse
This study will develop a therapy for men who have sex with men who also have a history of childhood sexual abuse to reduce behaviors that put them at a high risk of HIV infection.
- Trial name
- NCT00797654
- Testing
- Information-motivation-behavior skills and cognitive processing therapy, Pre and Post HIV-Test Counseling
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Fenway Community Health
Addictive Behavior, Adolescent Behavior
Prevalence of Internet Gaming Addiction in Adolescent
Excessive problematic use of the internet has been a topic of discussion in the academic literature for many years and has gained more attention recently. The majority of those at risk are in early adulthood.
- Trial name
- NCT04960254
- Testing
- internet gaming addiction
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cigarette Smoking, Veterans
Evaluating an Innovative Tobacco Treatment Approach for Veterans in Substance Use Treatment
Veterans with substance use disorders smoke at extraordinarily high rates and have high rates of smoking-related death and disease.
- Trial name
- Co-STOP (NCT07809854)
- Testing
- Healthy Changes Nicotine Replacement Therapy (NRT), Cessation Treatment Nicotine Replacement Therapy (NRT), Cessation Treatment Counseling
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- VA Office of Research and Development
Drug Use
Youth Drug Abuse Prevention in Kazakhstan
This pilot study will adapt and test the feasibility and estimate the effect size parameters of Kazakhstani Family Together (KFT), a family-based multi-media intervention designed to reduce sexual and drug-related risks for HIV…
- Trial name
- NCT01969305
- Testing
- Kazakhstani Family Together, Usual Care Alone
- Where
- Kazakhstan
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Depression, Anxiety
Caregiver Burden and Distress in Hematopoeitic Stem Cell Transplant
The purpose of this study is to examine the impact that serving as a caregiver for a patient undergoing hematopoietic stem cell transplant has on the caregiver.
- Conditions
- Depression, Anxiety, Fatigue, Distress
- Trial name
- NCT01084694
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northside Hospital, Inc.
Anxiety Disorders and Symptoms, Depressive Symptoms
Selective Prevention Transdiagnostic Intervention for At-risk Adolescents
Emotional disorders (anxiety and/or depression) are severely undiagnosed and untreated despite being among the most common mental disorders, particularly at a young age.
- Trial name
- PROCARE (NCT04851366)
- Testing
- PROCARE+ (with add-on modules), PROCARE (UP-A for selective purposes), Active control condition
- Where
- 3 sites in Spain
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Tobacco Use Cessation
Improving Adherence to Smoking Cessation Medication Among PLWHA
Smoking rates among individuals living with HIV/AIDS range between 47% and 65%, a prevalence that is roughly three times the rate of the general population.
- Trial name
- HIV (NCT01898195)
- Testing
- Varenicline, Text Message, Adherence Behavioral Therapy
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- NYU Langone Health
Obesity Type 2 Diabetes Mellitus, Obesity & Overweight
Eating Behaviour Before, During, and After Obesity Medication
This study will examine how eating behaviour changes during the first 18 months of treatment with obesity medications in patients attending the St Vincent's Healthcare Group obesity service.
- Trial name
- NCT07636395
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- University College Dublin
COPD
COPD Pal Phase 1: A Self-management App in COPD
Chronic Obstructive Pulmonary Disease (COPD) is a widespread condition which causes a poorer health status, reduced exercise, and lung function impairment.
- Trial name
- NCT04142957
- Testing
- COPD Pal
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Hywel Dda Health Board
Quality of Life
Effects of an Exercise Program on Reaction Time and Mouse Accuracy in Recreational Video Game Players
This study is intended to evaluate the effects of an exercise program on the change of electronic sports (esports) athletes' reaction time and mouse click accuracy.
- Trial name
- NCT06512675
- Testing
- Resistance combined with cardiovascular training
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Miami
Depression
Safety and Antidepressant Effects of Rellidep in Major Depressive Disorder
The investigators hypothesize that Rellidep will be effective in improving the symptoms of major depression. The available evidence strongly suggests that Rellidep contains a mood altering ingredient or ingredients.
- Trial name
- NCT00446719
- Testing
- Rellidep
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Mount Sinai Hospital, Canada
Emotional Regulation, Virtual Reality
E-Emotio Project A Gamified Preventive School-based Paradigm Using Virtual Reality Technologies for Improving Emotional Regulation in Children and Adolescents.
Introduction and Significance: Preventive interventions have been shown to reduce the risk of developing anxiety and depression, making them a critical focus area in mental health promotion for children and adolescents.
- Conditions
- Emotional Regulation, Virtual Reality, Anxiety, Depression
- Trial name
- e-Emotio (NCT06236919)
- Testing
- VR cognitive training, VR nature exposure relaxation
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Cirrhosis, Aerobic Exercises
The Efficacy of Aerobic Exercise Training on ANS and Endothelial Function in Compensated Cirrhosis
The goal of this randomized controlled trial is to investigate whether a 16-week structured aerobic exercise program combined with nutritional consultation can improve autonomic and endothelial function in patients with…
- Conditions
- Cirrhosis, Aerobic Exercises, Lifestyle Modification, Endothelial Function
- Trial name
- NCT06288828
- Testing
- Aerobic exercise + Nutrition consultant, Nutrition consultant
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Post-traumatic Stress Disorder, Depression
SimCoach Evaluation: A Virtual Human Intervention to Encourage Servicemember Help-seeking for PTSD and Depression
SimCoach, a computer program featuring a virtual human that speaks and gestures in a videogame-like interface, is designed to encourage servicemembers, especially those with signs or symptoms of post-traumatic stress disorder…
- Trial name
- NCT02335528
- Testing
- SimCoach
- Volunteers
- 333 people
- Sponsor
- RAND
Behavioral Changes
Effects of the Use of Multi Criterion Decision Analysis (MCDA) on Decision Quality in an Online Delphi
To examine the effects of using decision support tools during the online Delphi process.
- Trial name
- Delphi-MCDA (NCT03498365)
- Testing
- MCDA, Delphi
- Where
- United Kingdom
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- ThinkWell
HIV/AIDS
INcentives and ReMINDers to Improve Long-term Medication Adherence
The study will test the feasibility and acceptability of using text messages and behavioral economics-based incentives to support anchoring Anti-Retroviral Therapy (ART) adherence to an existing routine in order to improve…
- Trial name
- INMIND (NCT05131165)
- Testing
- Daily Text Messages, Incentivization based on timely ART adherence
- Where
- Uganda
- Volunteers
- 166 people
- Sponsor
- RAND
Wrist Fractures, Distal Radius Fractures
Unilateral Training of the Uninjured Limb on Clinical Outcomes in Patients with Surgically Treated Radius Fracture
The objective will be to determine the effectiveness of adding unilateral upper limb postoperative training to standard rehabilitation compared to standard rehabilitation on maximum grip strength and manual dexterity in patients…
- Trial name
- NCT06698367
- Testing
- Standard rehabilitation, Unilateral high-intensity strength exercise, Unilateral mobility exercises
- Where
- Chile
- Volunteers
- 52 people
- Sponsor
- Universidad Catolica de Temuco
Mood Disorders, Anxiety Disorders
Online Training for Addressing Perinatal Depression
The study team is developing an e-learning course to train obstetric providers to address perinatal mood and anxiety disorders. The study team will conduct a formative evaluation of the e-learning course with 10 obstetric…
- Trial name
- NCT04919967
- Testing
- Virtual implementation protocol, e-learning toolkit
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Anxiety, Depression / Major Depressive Disorder
The Effectiveness of a One-stop Electronic Clinic for Psychological Service (eClinic) in Hong Kong
With an increasing need for effective and accessible mental health services, telepsychology can be one promising solution to narrowing the gap between demand and supply.
- Conditions
- Anxiety, Depression / Major Depressive Disorder, Common Mental Disorder
- Trial name
- NCT07597967
- Testing
- Internet-based Unified Protocol (UP) Intervention
- Where
- Hong Kong
- Volunteers
- 420 people
- Sponsor
- New Life Psychiatric Rehabilitation Association
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