Clinical trials: Conduct
Anorexia Nervosa/Bulimia, Anorexia in Adolescence
Oral Naltrexone In Pediatric Eating Disorders
The objective of this study is to evaluate the effectiveness of oral naltrexone tablets in pediatric and adolescent eating disorders, in particular anorexia nervosa and bulimia nervosa, as compared to placebo.
- Conditions
- Anorexia Nervosa/Bulimia, Anorexia in Adolescence, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type
- Trial name
- ONPED (NCT05073679)
- Testing
- Naltrexone Hydrochloride, Control
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rosemary Claire Roden
Depression, Menopause
Vortioxetine for Menopausal Depression
The broad goal of this study was to examine the efficacy and tolerability of vortioxetine (flexible dose) for the treatment of major depressive disorder (MDD) in symptomatic women around the menopausal transition.
- Conditions
- Depression, Menopause, Vasomotor Disturbance, Hot Flashes
- Trial name
- NCT02234362
- Testing
- vortioxetine
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Massachusetts General Hospital
Anxiety, Depression
Collaborative Care for Women Veterans
Implementation of Tailored Collaborative Care for Women Veterans (CCWV) was designed to enhance primary care-mental health integration for women Veterans by tailoring services to women Veterans' and providers' needs and providing…
- Conditions
- Anxiety, Depression, Stress Disorders, Post Traumatic
- Trial name
- CCWV (NCT02950961)
- Testing
- Collaborative Care for Women Veterans
- Where
- 3 sites in United States
- Volunteers
- 153 people
- Sponsor
- VA Office of Research and Development
Cerebrovascular Disorders, Smoking Cessation
Efficacy and Cost-Effectiveness of Cost-free Pharmacotherapy for Smoking Cessation for High-risk Smokers With Cerebrovascular Disease
Research Aims The aims of this research study are to determine whether cost-free smoking cessation pharmacotherapy: 1. Helps smokers with Transient Ischemic Attack (TIA) or stroke to quit smoking over the long-term, compared to…
- Trial name
- NCT00962988
- Testing
- Cost-Free Pharmacotherapy Group, Prescription Only Group
- Where
- 2 sites in Canada
- Volunteers
- 194 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Diabetes Mellitus, Depression
CBT for Adherence and Depression in Diabetes
This study will evaluate the effectiveness of cognitive behavioral therapy (CBT) in treating people with depression and type 2 diabetes.
- Trial name
- NCT00564070
- Testing
- Enhanced treatment as usual plus adherence training, Enhanced treatment as usual plus CBT-AD
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Massachusetts General Hospital
Medication Adherence
Imagine to Remember: Improving Medication Adherence in Pre- and Type 2 Diabetes
Determine if an intervention consisting of future-thinking improves different facets of memory/executive function and/or decision-making.
- Trial name
- NCT04157673
- Testing
- Episodic Future Thinking
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Smoking
Very-Low Nicotine Cigarettes and Non-Daily Smokers
The purpose of this research study is to investigate the impact of different nicotine levels in cigarettes among non-daily smokers.
- Trial name
- NCT02228824
- Testing
- Very low nicotine content cigarettes, Normal nicotine content cigarettes
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- Saul Shiffman
Obesity
Mobile Device Biomonitoring to Prevent and Treat Obesity in Underserved Youth
This project proposes to use mobile devices to develop new tools for pediatric obesity prevention and treatment targeting underserved minority adolescent populations at high risk for obesity and related diseases.
- Trial name
- KNOWME (NCT02017223)
- Testing
- Knowme Device Wear
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Rheumatic Diseases, Gout
Medication Adherence Patterns in Rheumatic Diseases: A Behavioral Trial
Non-adherence to evidence-based prescription medications results in preventable morbidity and mortality for middle-aged and older adults.
- Conditions
- Rheumatic Diseases, Gout, Adherence, Medication, Lupus Erythematosus, Systemic
- Trial name
- NCT04776161
- Testing
- Cue-Reward Intervention, Cue-Reward Intervention with possible intensification
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Brigham and Women's Hospital
Metabolic Syndrome, Type 2 Diabetes
Lifestyle Intervention for Pakistani Women in Oslo
Immigrants from South Asia in Norway have a high prevalence of type 2 diabetes and conditions related to the metabolic syndrome. It has been documented that these conditions may be prevented by changes in lifestyle.
- Trial name
- InnvaDiab (NCT00425269)
- Testing
- lifestyle intervention (diet and physical activity)
- Where
- Norway
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Smoking Cessation
Smoker-to-Smoker (S2S) Peer Marketing and Messaging to Disseminate Tobacco Interventions
The research study, "Smoker-to-Smoker (S2S) Peer Marketing and Messaging to Disseminate Tobacco Interventions" will test two smoker-driven, social marketing innovations to recruit and engage smokers in Decide2Quit.org…
- Trial name
- NCT03224520
- Testing
- Recommender CTHC, Standard CTHC, Peer Recruitment
- Where
- United States
- Volunteers
- 1,487 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Adherence, Medication
Alterations in the Vaginal Microenvironment Using a Non-pharmacological Intervention
Breast cancer patients commonly take medications to reduce the risk of recurrence, including aromatase inhibitors (AIs). AIs can cause significant side effects that reduce patient adherence.
- Trial name
- NCT03739983
- Testing
- Vaginal Renewal Program
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Wisconsin, Madison
Surgery, Adolescent Behavior
Recruitment and Behavioral Economic Strategies
To determine the impact of the application of behavioral economic strategies on recruitment of pediatric patients into a randomized clinical trial assessing the impact of technology-based interventions on postoperative pain…
- Trial name
- NCT05441579
- Testing
- Behavioral Economics (BE) recruitment strategies, Biofeedback-based virtual reality (VR-BF), Manage My Pain
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Vanessa Olbrecht
Smoking Cessation
Post-Discharge Smoking Cessation Strategies: Helping HAND 4
This randomized controlled trial will compare the effectiveness of two models of post-discharge tobacco cessation treatment for adult smokers admitted to 3 U.S. hospitals.
- Trial name
- HH4 (NCT03603496)
- Testing
- Transitional Tobacco Care Management (TTCM), eReferral to State Tobacco Quitline (QL), Nicotine replacement therapy
- Where
- 3 sites in United States
- Volunteers
- 1,416 people
- Sponsor
- Massachusetts General Hospital
Cough
Effect of Electronic Cigarette Use on Cough Reflex Sensitivity
Although electronic cigarettes (e-cigs) are now widely used, very little information exists regarding the effect of electronic cigarette use (vaping) on the respiratory system.
- Trial name
- NCT02203162
- Testing
- electronic cigarette exposure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Depression, Major Depressive Disorder
Effects of Low Dose Ketamine Given at Induction of Anesthesia on Postoperative Mood in Patients With Depressive Symptoms
Ketamine has been shown to have an antidepressant effect when given intravenously in doses of 2mg/kg. Ketamine is used as a standard induction drug during general anesthesia.
- Trial name
- NCT02422303
- Testing
- ketamine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Mild Cognitive Impairment
Intervention to Reduce Sedentary Time
The purpose of this study is to determine whether the researchers can help people change the amount of time they spend in sitting activities and whether this change might improve health outcomes.
- Trial name
- ReST-MCI (NCT02878486)
- Testing
- Jawbone Up, Physical Activity Education, ActivPAL
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Kansas Medical Center
Asthma Chronic, Adherence, Medication
Pictograms to Facilitate Comprehension of Medical Indications
SIMAP is a triple-masked randomised trial aimed at assessing whether an automated system of pictograms associated to medical indications results in better comprehension and adherence of said indications.
- Conditions
- Asthma Chronic, Adherence, Medication, Primary Health Care
- Trial name
- SIMAP (NCT05609760)
- Testing
- SIMAP, Usual Care
- Where
- 4 sites in Chile
- Volunteers
- 22 people
- Sponsor
- Universidad de Concepcion
Type 2 Diabetes Mellitus, Fear of Hypoglycemia
Effects of a Health Intervention on Fear of Hypoglycemia : a Pilot Study
The purpose of this study was to construct a Fear of Hypoglycemia(FoH) intervention program for type 2 diabetic patients based on the Behaviour Change Wheel (BCW) theory and to investigate the feasibility, acceptability, and…
- Conditions
- Type 2 Diabetes Mellitus, Fear of Hypoglycemia, Health Education, Impaired Awareness of Hypoglycemia
- Trial name
- NCT06197360
- Testing
- Based on BCW Theory of Health Education, General diabetes health education
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Yangzhou University
Addiction, Depression/Anxiety
Healing Lodge First Face Training Evaluation Study
The purpose of this study is to evaluate a culturally grounded training program, xaʔtus (meaning First Face) for Mental Health. This program will train community members in how to recognize and respond to youth and adults…
- Conditions
- Addiction, Depression/Anxiety, Trauma, Psychological, Self-harm
- Trial name
- NCT06290180
- Testing
- First Face for Mental Heatlh
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
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