Clinical trials: Confusion Postoperative
Pain, Acute
Validation of the Polish Version of BPS (POL-BPS).
Between 40 to 70% of patients with critical illness experience moderate to severe pain. Diagnosing pain and assessing its severity is difficult in non-verbal patients both in an Intensive Care Unit and in Postoperative Unit after…
- Trial name
- POL-BPS (NCT03127306)
- Testing
- Assessment of Polish version of BPS
- Where
- Poland
- Volunteers
- 59 people
- Sponsor
- Pomeranian Medical University Szczecin
Postoperative Delirium (POD), Prostate Cancer
A Phase II Clinical Two-Stage Study of Transcranial Magnetic Stimulation in Preventing Postoperative Delirium in Elderly Patients After Urological Surgery
Cases were included based on the inclusion and exclusion criteria, and induction, maintenance, and recovery were conducted in accordance with the standard protocol for general anesthesia.
- Conditions
- Postoperative Delirium (POD), Prostate Cancer, Kidney Tumor
- Trial name
- NCT07480044
- Testing
- Transcranial Magnetic Stimulation Device
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Zhejiang University
Emergence Delirium
Emergence Agitation of Sevoflurane in Pediatric
Low dose nalbuphine versus dexmedetomidine on prevention of emergence agitation in children
- Trial name
- NCT06830564
- Testing
- we will give the patient 0.1 mg nalbuphine 15 min before the end of the procedure, we will give the patient 0.5 mg dexmedetomidine 15 min before the end of the procedure
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Delirium
Clinical Investigation of an Eye-Tracking Device as a Predictor of Delirium in the Recovery Room After Surgery With General Anesthesia
Neurotrack™ is an FDA-approved device for measuring and tracking cognitive decline, as may occur with age-related cognitive decline and Alzheimer's disease.
- Trial name
- NCT05579093
- Testing
- Cognitive test + Pupillary measure
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Columbia University
Delirium, Post-Operative States
Namenda to Prevent Post-Operative Delirium
Post Operative Delirium is a common and serious risk of surgery. Delirium, when it occurs is associated with an increased risk of mortality, increase length of stay, and more adverse outcomes in general, including increased risk…
- Trial name
- NCT00303433
- Testing
- Namenda
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Rochester
Postoperative Cognitive Dysfunction, Mild Cognitive Impairment
Cognitive Changes After Major Joint Replacement
Patients assume that cognitive performance rapidly returns to baseline after anesthesia and surgery. Several studies have shown that one week after major non-cardiac surgery about 27% of patients have postoperative cognitive…
- Conditions
- Postoperative Cognitive Dysfunction, Mild Cognitive Impairment, Delirium, Cognitive Deficit
- Trial name
- Cognigram (NCT02964221)
- Testing
- Cognitive Testing
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dr. Stephen Choi
Preoperative Anxiety, Postoperative Delirium
The Effect of Preoperative Anxiety on Postoperative Delirium in Children
Investigation of the effect of preoperative anxiety on postoperative delirium in children who will undergo circumcision operation
- Trial name
- NCT04009200
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Diskapi Training and Research Hospital
Pseudomyxoma Peritonei, Postoperative Delirium (POD)
Proactive Temperature Management in CRS-HIPEC for Prevention of Delirium
This randomized controlled trial evaluates the efficacy of a proactive Goal-Directed Temperature Management (GDTM) protocol in reducing postoperative delirium among patients undergoing Cytoreductive Surgery (CRS) with…
- Trial name
- NCT07378371
- Testing
- Proactive Goal-Directed Temperature Management, Standard Reactive Temperature Management
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Aerospace Center Hospital
Delirium, Postoperative Cognitive Dysfunction
Dexamethasone and Postoperative Delirium
Postoperative delirium is commonly observed in elderly patients in the postanesthesia care unit (PACU) and during the first 2-3 days following surgical procedures.
- Trial name
- NCT02109081
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Endeavor Health
Diabetes, Postoperative Delirium
Predictive Effect of TGF-β and INS-PI3K-AKT Related Proteins for POD in Diabetes Patients
To investigate the relationship between POD, TGF-β and INS-PI3K-AKT signaling pathway related proteins (ADNP, MAP6, PGC-1α) in diabetic patients
- Trial name
- NCT06426953
- Testing
- No intervention
- Where
- 2 sites in China
- Volunteers
- 180 people
- Sponsor
- Xie Kangjie
Postoperative Delirium (POD)
Validation of a Risk Assessment Model for Postoperative Delirium Based on Artificial Intelligence
Postoperative delirium (POD) is a frequent postoperative complication in the elderly, characterised by fluctuating disturbances in attention, awareness, and cognition.
- Trial name
- NCT05639348
- Testing
- Data collection on POD for calculation of the PIPRA score
- Where
- 3 sites in Switzerland
- Volunteers
- 993 people
- Sponsor
- University Hospital, Basel, Switzerland
Emergence Delirium
Premedication With Intranasal Dexmedetomidine or Midazolam for Prevention of Emergence Agitation in Children
Study where children will receive one premedication, either intranasal dexmedetomidine or oral midazolam, to reduce agitation on emergence of anesthesia.
- Trial name
- NCT03171740
- Testing
- Dexmedetomidine, Midazolam oral solution, Oral saline
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- Brasilia University Hospital
Post-Operative Confusion
Braindex Cerebral Tissue Oxygen Saturation (SctO2) Measurement Algorithm Assessment and Improvement
The objective of this clinical trial is to optimize Braindex brain tissue oxygen saturation (SctO2) measurement algorithm compared to a mixed reference value of jugular venous and systemic arterial saturation, during proven…
- Trial name
- POC-SctO2 (NCT05897060)
- Testing
- Venus Jugular O2 Saturation optical fiber
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Braindex
Emergence Agitation, Pain
Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery
The purpose of this study is to compare the incidence of EA in pediatric patients undergoing minor ENT surgery under Sevoflurane and compare opioid-only based intra-operative analgesia to multi-modal analgesia consisting of…
- Trial name
- NCT03062488
- Testing
- IV acetaminophen, Fentanyl, PO acetaminophen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Emergence Agitation
Effects of Preoperative Child and Parental Anxiety on Emergence Agitation
Investigation of the effect of preoperative parental anxiety and sociodemographic characteristics on emergence agitation in patients undergoing pediatric adenotonsil surgery
- Trial name
- NCT07486427
- Testing
- No intervention - observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Ondokuz Mayıs University
Delirium
Standardization of a Novel Self-administered Tablet Computer-based Clinical Screening Tool for Adverse Postoperative Cognitive Outcomes
Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are common complications after surgery and may affect elderly patients in particular.
- Trial name
- CogCheck-Norm (NCT02708823)
- Testing
- CogCheck application
- Where
- Switzerland
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Nicolai Goettel
Postoperative Delirium, Sarcopenia
Effect of Preoperative Sarcopenia on Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Surgery
The goal of this observational study is to compare Incidence of postoperative delirium in Sarcopenic and non-sarcopenic elderly patients undergoing gastrointestinal surgery.
- Conditions
- Postoperative Delirium, Sarcopenia, Gastrointestinal Surgery, Anesthesia
- Trial name
- NCT05847296
- Where
- China
- Volunteers
- 334 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Delirium, Neurocognitive Disorders
Turkish Precision Anaesthesia Study Project
Postoperative delirium (POD) and postoperative neurocognitive disorder (PND) increase the length of hospital stay, morbidity and mortality, especially in elderly patients.
- Trial name
- TuPASProject (NCT05872529)
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Stress Response
Effect of Dexmedetomidine on Stress Response and Emergence Agitation During Laparoscopic Surgery
Emergence agitation is a post-anesthetic phenomenon that develops in the early phase of general anesthesia recovery, and is characterized by agitation, confusion, disorientation, and possible violent behavior.
- Trial name
- NCT02917018
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Surgery, Postoperative Delirium
Intraoperative Diagnosis of Neurocognitive Complications Via Electroencephalographic Analysis
Postoperative neurocognitive disorders (PND) are serious and common complications after surgery, especially in elderly patients.
- Conditions
- Surgery, Postoperative Delirium, Anesthesia, Silent Stroke
- Trial name
- NCT06545786
- Testing
- Intraoperative electroencephalography
- Where
- Russia
- Volunteers
- 265 people
- Sponsor
- Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology