Clinical trials: Confusional State
POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE, Heart Rate Variability
Predicting Postoperative Delirium With Heart Rate Variability Obtained by Analgesia Nociception Index
The aim of this pilot study is to establish a correlation between perioperative heart rate variability (HRV) as an expression of the shift in the balance of the autonomic nervous system and the occurrence of postoperative…
- Conditions
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE, Heart Rate Variability, Biomarkers
- Trial name
- DANI (NCT06709482)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Delirium
The Effect of Music Therapy on Delirium
The purpose of this study is to test the effect of a twice daily, 30-minute, interdisciplinary, music therapist developed, nurse initiated, music listening intervention on acutely ill older patients as compared to patients who…
- Trial name
- NCT03980782
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Delirium, Hospital Acquired Condition
Earplugs and Eye Masks for Reducing Delirium
There has been some recent evidence to support the use of earplugs and eye masks to prevent delirium, but the existing studies have been small, have not been thoroughly replicated, and have only been conducted with intensive care…
- Trial name
- NCT03471520
- Testing
- Earplugs and eye masks
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Duke University
Delirium, Copd
ABCDEF Bundle to Prevent Delirium for COPD Patients
Abstract Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory disorder characterized by persistent airflow limitation and chronic respiratory symptoms, resulting from abnormalities in the bronchi…
- Conditions
- Delirium, Copd, Nurse's Role
- Trial name
- COPD (NCT06974318)
- Testing
- ABCDEF Bundle to Prevent Delirium, Standard Care to Prevent Delirium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Delirium, Cognitive Impairment
Preoperative BAMCOG and Cortisol and Postoperative DeltaScan in AVR Patients (Aortic Valve Replacement)
There is lack of attention to preoperative cognitive function and delirium in elderly who underwent surgery. The investigators are investigating different tools that can help to screen for cognitive dysfunction and delirium in…
- Conditions
- Delirium, Cognitive Impairment, Cognitive Dysfunction, Cognitive Dysfunction, Postoperative
- Trial name
- NCT05209555
- Testing
- MoCA, BAMCOG, DeltaScan
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Postoperative Delirium, Postoperative Pain, Acute
Postoperative Delirium and Analgesia in Elderly Patients
This study aims to evaluate the effects of different postoperative analgesic approaches on postoperative delirium in elderly patients undergoing total knee arthroplasty.
- Trial name
- NCT07849517
- Testing
- adductor canal block and biFes block including bupivacain, Periarticular infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Surgery, Stress
The Effects of Healing Touch on Post Operative Pediatric Patients
The goal of this study is to assess the benefits of Healing Touch, an energy based therapy on post-operative discomfort and the rate of recovery in children.
- Conditions
- Surgery, Stress, Pain, Children
- Trial name
- NCT01738308
- Testing
- Healing Touch
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Delirium, Sedation Complication
The Relationship Between Fasting Time and Delirium
We investigated the relationship between fasting times and delirium in children undergoing MRI under anesthesia. Paediatric Anaesthesia Emergence Delirium (PAED) scale, last oral intake time and type of food (solid-liquid) and…
- Conditions
- Delirium, Sedation Complication, Magnetic Resonance Imaging, Fasting
- Trial name
- NCT05567718
- Testing
- Paediatric Anaesthesia Emergence Delirium scale
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Postoperative Delirium, Postoperative Cognitive Dysfunction
Greek Validation of ACE III Test in Perioperative Patients
Postoperative neurocognitive disorders, including postoperative delirium (POD) and postoperaive cognitive dysfunction (POCD), are common complications of perioperative neurocognition in elderly patients undergoing surgery.
- Trial name
- NCT04312516
- Where
- Greece
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Postoperative Complications, Delirium
Donepezil in Preventing Delirium in Hospitalized Elderly
The purpose of this study is to explore the efficacy of a perioperative daily dose of Donepezil (a cholinergic enhancer) in reducing the incidence and severity of delirium.
- Trial name
- NCT00182884
- Testing
- Donepezil
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University Health
Child, Anesthesia Morbidity
Propofol for Treatment on Emergence Agitation
This study aimed to verify the effects of propofol for treatment on emergence agitation (EA) after sevoflurane anesthesia in pediatric strabismus surgery.
- Trial name
- NCT02738814
- Testing
- propofol
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Delirium - Postoperative
Effectiveness of Electroencephalography Guided Anesthesia
This study will use brain wave information, known as electroencephalography (EEG), to help guide anesthesia delivery during surgery.
- Trial name
- EEG Anesthesia (NCT07567729)
- Testing
- EEG-guided anesthesia training program for anesthesia providers, EEG-Guided Intervention
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Stanford University
Confusion Postoperative, Delirium
Preoperative Prognostic Nutritional Index and Postoperative Delirium in Gastrointestinal Cancer Surgery
Aim: We aimed to show the relationship between preoperative prognostic nutritional index and postoperative delirium in patients who had undergone gastrointestinal cancer surgery.
- Conditions
- Confusion Postoperative, Delirium, Gastrointestinal Cancer, Nutritional Deficiency
- Trial name
- NCT06603129
- Testing
- prognostic nutritional index
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Disorientation as to People, Time and Place
Proposal to Examine the Effect of Fecal Transplantation on Obesity
The investigators propose to transplant feces from thin, disease-free donors into obese patients undergoing colonoscopy for screening for colorectal carcinoma.
- Trial name
- NCT02336789
- Testing
- fecal material, normal saline
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kaplan Medical Center
Delirium
Quetiapine as Prophylaxis for Delirium in CABG
low-dose quetiapine may be effective in preventing delirium in patients. The purpose of this study is to evaluate the efficacy and safety of quetiapine for delirium prophylaxis in cabg
- Trial name
- NCT05801289
- Testing
- Quetiapine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Emergence Delirium, Anxiety Preoperative
Comparative Study Between Nebulised Dexmedetomidine and Nebulised Midazolam in Children Undergoing Lower Abdominal Surgeries
Comparative study between nebulised dexmedetomidine and nebulized midazolam in reducing preoperative anxiety and emergence delirium in children undergoing lower abdominal surgeries
- Trial name
- NCT05872087
- Testing
- Nebulised Dexmeditomidine, Nebulised Midazolam
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Delirium
The ABCDEF Bundle in Critical Care: a French National Survey Still a Long Way to go!
The goal of this observational study is to evaluate the knowledge and compliance of French intensive care units with the ABCDEF (A: Assessment, Prevention, Management of Pain, B: Both Spontaneous Awakening Trials and Spontaneous…
- Trial name
- NCT06344013
- Where
- France
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Sleep Disorders
Protocol For Sleep for Critically Ill Patients
Sleep is essential for health and well-being. The quality of sleep impacts physical and cognitive aspects, including memory, immune system, and neuroendocrine function, with abnormalities associated with cardiovascular changes…
- Trial name
- NCT05996861
- Testing
- ICU sleep protocol
- Where
- 2 sites in Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Moinhos de Vento
Delirium of Mixed Origin, Microbial Colonization
The Gut Microbiota and Delirium in the ICU
To investigate whether the composition of the gut microbiota is different in patients that develop delirium during critical illness as compared to patients who do not.
- Trial name
- GuMDel-ICU (NCT03328377)
- Testing
- Metagenomic analysis of gut microbiota
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Implementation Science, Delirium
Determinants of Implementation Success Coordinating Ventilator, Early Ambulation and Rehabilitation Efforts
There is a fundamental gap between the discovery of proven-effective intensive care unit (ICU) sedation, mechanical ventilation, mobility, and symptom management strategies and approaches that can equip ICU providers with the…
- Conditions
- Implementation Science, Delirium, Intensive Care Unit Acquired Weakness, Pain
- Trial name
- DISCOVER-ICU (NCT04249141)
- Testing
- Survey and concept mapping
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio State University