Clinical trials: Congenital Disorder
Capillary Malformation, Laser
Assessing the Effects of Air-cooling on Capillary Malformations
The purpose of this observational study is to ascertain the effects of cutaneous air cooling on vessel diameter within Capillary Malformations (CM).
- Conditions
- Capillary Malformation, Laser, Skin Cooling
- Trial name
- NCT01735734
- Testing
- Air cooling to CM site
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Health Service, United Kingdom
Maxillary Hypoplasia, Retrognathia
CT Analysis of the Anatomy of the Nasotracheal Intubation Pathway of Patients With Indication of Maxillary Advancement
Differences in nasotracheal intubation pathway anatomy will be observed between healthy patients and patients with maxillary retrusion. The results will clarify the nasotracheal intubation tube preference for these patients.
- Conditions
- Maxillary Hypoplasia, Retrognathia, Intubation, Tomography
- Trial name
- NCT03570528
- Where
- Turkey (Türkiye)
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Ankara University
Congenital Heart Disease
Study on the Relationship Between Maternal Exposure to Environmental Factors and Fetal Congenital Heart Disease
The objective of this study is to research the relationship between maternal exposure to environmental factors and fetal congenital heart disease in a community-based case-control study.
- Trial name
- NCT02914392
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Psoriasis, Atopic Dermatitis
Impact of the Severity of Pediatric Psoriasis on Childhood Body Mass Index
The object of this research study is to examine these associations in children as very little is known about psoriasis and cardiovascular risk factors in the pediatric population.
- Trial name
- NCT00879944
- Testing
- Blood pressure, Height, Weight
- Where
- 14 sites in United States, Canada and 4 more
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Atopic Dermatitis (AD), Eczema
Ph 1a/1b Single Ascending Dose and Multiple Ascending Dose Study of ARQ-234
This is a first-in-human, Phase 1, double-blind, randomized, placebo-controlled, dose-escalation study evaluating ARQ-234. The study is designed to assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD)…
- Trial name
- NCT07453602
- Testing
- ARQ-234
- Where
- 7 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Arcutis Biotherapeutics, Inc.
Healthy
The Efficacy of Vitamin K2 n Human Osteoporosis, Blood-vessel Calcification and Sclerosis
This study used the generally recognized as safe (GRAS) grade of Bacillus subtilis natto to produce Vitamin K2, Menaquinone-7(MK-7), via fermentation, for functional evaluation.
- Trial name
- NCT01928134
- Testing
- Vit K2+ Vit D3+ calcium carbonate (CaCO3), Vit K2+CaCO3
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Changhua Christian Hospital
Embolic Stroke of Undetermined Source, Ischemic Stroke
Biomarkers, Hemodynamic and Echocardiographic Predictors of Ischemic Strokes and Their Influence on the Course and Prognosis
A stroke is the second cause of deaths after heart attack, one of the most important causes of malfunction as far as adults are concerned and the second as for the frequency cause of dementia.
- Conditions
- Embolic Stroke of Undetermined Source, Ischemic Stroke, Atrial Fibrillation and Flutter, Myocardial Infarction
- Trial name
- NCT03377465
- Testing
- ADMA (asymmetric dimethylarginine) , NTproBNP (N-terminal pro b-type natriuretic peptide), IL-6 (Interleukin 6), Adiponectina, Leptine, Syndecan, Resistin
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Behcet Disease
Role of Regulatory B Cells in Behçet's Disease
There are limited data about the role of regulatory B cells in Behcet Disease. In this study we aimed to identify the proportions of total B lymphocytes and their regulatory subset in different Behcet Disease phenotype and…
- Trial name
- NCT04376411
- Testing
- Flow-cytometric assay, 2D Echocardiographic analysis, Two-Dimensional speckle tracking echocardiography
- Where
- Egypt
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cardiomyopathy, Hypertrophic, Cardiomyopathy, Dilated
Individualized Early Risk Assessment for Heart Diseases
Heart failure (HF) is the common end-stage of different medical conditions. It is the only growing cardiovascular disease and its prognosis remains worse than that of many malignancies.
- Trial name
- IndivuHeart (NCT02417311)
- Testing
- Skin biopsy, genotyping and disease phenotyping
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cystic Fibrosis
Longitudinal Assessment of Exercise Capacity and Vascular Function in Patients With CF
This project is an attempt to understand how Orkambi treatment affects exercise capacity and the function of the arteries in CF patients who are homozygous F508del.
- Trial name
- NCT03338595
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Augusta University
Molar Incisor Hypomineralization
Comparative Evaluation of Giomer Varnish vs Fluoride Varnish as Desensitizing Agents in Teeth With MIH
this clinical trial's aim is to compare two desensitizing agents available in the market to prove which one is more efficient in children with molar incisor hypomineralization complaining from hypersensitivity
- Trial name
- NCT05542667
- Testing
- Giomer varnish, Fluoride varnish
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Behçet
Role of Femoral Vein Wall Thickness and Inflammatory Markers in Patients With Behcet Disease
Evaluation of femoral vein wall thickness and inflammatory indices in patients with Behcet disease and assessment of their relation to the disease activity and related some clinical manifestations
- Trial name
- NCT06721234
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Missing Teeth
Short-term Observation on the Clinical Application Effect of Astra Tech Implant EV Short Implants for Maxillary Sinus Elevation
Short-term comparison of clinical application effects of Astra OsseoSpeed EV short implants and conventional implants for maxillary sinus elevation
- Trial name
- NCT07271134
- Testing
- short implants (L=6.3mm), short implants (L=8mm), conventional implants (L=9mm)
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Linhu Wang
Cerebral Palsy, Spina Bifida
Virtual Peer Health Coaching for Adolescents With Disabilities
Participation in physical activity (PA) confers clear physical and psychosocial benefits. Yet, many adolescents with physical disabilities such as cerebral palsy and spina bifida do not engage in regular PA, putting them at…
- Trial name
- NCT05587634
- Testing
- Virtual Peer Health Coaching
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Post-exercise Period, Ketosis
Acute Effects of Ketone Monoester Co-ingestion With Dietary Protein on Whole-body Phenylalanine Oxidation, Phenylalanine Retention, and Myofibrillar Protein Breakdown Following Resistance Exercise in Young Males.
The goal of this trial is to determine if ketone monoester supplementation in conjunction with protein supplementation in the post exercise period can augment whole-body protein metabolism following resistance exercise in young…
- Conditions
- Post-exercise Period, Ketosis, Resistance Exercise, Dietary Protein
- Trial name
- (KET-YOUNG-M) (NCT07884539)
- Testing
- Ketone Monoester + Dietary Protein (KET+PRO), Dietary Protein (PRO), Resistance Exercise
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- McGill University
Postpartum Psychological Stress, Mindfulness-Based Stress Reduction
Effect of Mindfulness-Based Stress Reduction on Birth Memory and Perception of Traumatic Birth
This randomized controlled trial aims to evaluate the effects of a Mindfulness-Based Stress Reduction (MBSR) program on birth memory and perception of traumatic birth among women who have undergone vaginal delivery.
- Conditions
- Postpartum Psychological Stress, Mindfulness-Based Stress Reduction, Maternal Health, Traumatic Birth
- Trial name
- MBSR-BIRTH (NCT07018765)
- Testing
- Mindfulness-Based Stress Reduction (MBSR)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kader ATABEY
Healthy Volunteers, Vascular Ehlers Danlos Syndrome
Non-Invasive Quantitative Imaging of Human Local Arterial Wall Elasticity Using Supersonic Shear Imaging
Arterial stiffness is associated with increased risk of cardiovascular events and death. Most of existing technique need dedicated device for arterial stiffness evaluation and indirect calculation of intra arterial pressure.
- Trial name
- ULTRAFASTECHO (NCT01096264)
- Testing
- SSI and SphygmoCor® evaluations
- Where
- France
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- French Cardiology Society
Flat Feet, Flexible Flatfoot
Effect of Insole Added to Exercise in Patients With Bilateral Flexible Flatfoot
Pesplanus, commonly known as 'flatfoot,' is a common pathomechanical condition characterized by a lowered medial longitudinal arch (MLA) and exaggerated pronation.
- Conditions
- Flat Feet, Flexible Flatfoot, Balance; Distorted, Muscle Weakness
- Trial name
- NCT05056298
- Testing
- Custom made insole, Strengthening exercises of extrinsic foot muscles, Strengthening exercises of intrinsic foot muscles
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Horus University
Duchenne Muscular Dystrophy
The Validation Process for Confirmation of the French Version of the Pediatric Quality of Life Inventory :PedsQLTM.
There isn't specific Health related quality of life measure for children with DMD in French. The aim of this study is to validate the French version of the Pediatric Quality of Life Inventory 3.0 Duchenne Muscular Dystrophy…
- Trial name
- ValPedsQLDMD (NCT03513367)
- Testing
- Duchenne Muscular Dystrophy of the PedsQL ™ 3.0 scale, The following data of motor function
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Phenylketonuria, Galactosemia
The Early History of Universal Screening for Metabolic Disorders
We are doing this study to learn more about the early history of universal screening for metabolic disorders such as PKU and galactosemia.
- Conditions
- Phenylketonuria, Galactosemia, Inborn Errors of Metabolism
- Trial name
- NCT00309400
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Miami
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