Clinical trials: Congenital Glaucoma
Glaucoma, Congenital Cataract
Glaucoma After Congenital And Infantile Cataract Surgery
Pediatric patients who have undergone surgery for congenital or infantile cataracts have a risk of developing suspected glaucoma and glaucoma, but the current evidence does not address our understanding of the incidence and…
- Trial name
- NCT04131114
- Where
- China
- Volunteers
- 241 people
- Sponsor
- Sun Yat-sen University
Graft vs Host Disease, Congenital Aniridia
Safety and Performance Study of the ARGOS-IO System in Patients Undergoing Boston Keratoprosthesis Implantation
The ARGOS-IO pressure sensor is intended to be implanted in the human eye in combination with Boston Keratoprosthesis (BKPro) surgery and to remain in place indefinitely.
- Conditions
- Graft vs Host Disease, Congenital Aniridia, Chemical Burns, Stevens-Johnson Syndrome
- Trial name
- NCT02945176
- Testing
- ARGOS-IO system
- Where
- 2 sites in Germany
- Volunteers
- 13 people
- Sponsor
- Implandata Ophthalmic Products GmbH
Retinitis Pigmentosa, Maculopathy, Age Related
Bimodal and Coaxial High Resolution Ophtalmic Imaging
The knowledge of the pathogenesis of retinal affections, a major cause of blindness, has greatly benefited from recent advances in retinal imaging.
- Conditions
- Retinitis Pigmentosa, Maculopathy, Age Related, Macular Dystrophy, Macular Edema
- Trial name
- AOSLO-OCT (NCT04620876)
- Testing
- Bimodal high resolution imaging of the retina
- Where
- France
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Cognitive Behavioral Nursing, Congenital Glaucoma
Cognitive Behavioral Nursing Model
Materials and Methods 1. General information This study enrolled 153 patients with congenital glaucoma who were treated at our hospital from January 2021 to December 2022.
- Trial name
- NCT05943184
- Testing
- Cognitive Behavioral Nursing Model
- Where
- China
- Volunteers
- 153 people
- Sponsor
- Taiyuan Central Hospital of Shanxi Medical University
Congenital Cataract, Aphakic or Pseudophakic Glaucoma
Mechanism of Aphakic and Pseudophakic Glaucoma in Pediatric Patients
In cell cultures, lens epithelial cells and trabecular meshwork cells will be exposed to aqueous humor from pediatric eyes undergoing cataract removal surgery.
- Trial name
- NCT01136473
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Carmel Medical Center
Thyroid Eye Disease, Ocular Hypertension
The Secondary Beneficial Effects of Prostaglandin Analog Treatment in Thyroid Eye Disease Patients.
The purpose of this study is to evaluate the potential secondary beneficial effect of prostaglandin analogues (PA) treatment in thyroid eye disease (TED) patients.
- Conditions
- Thyroid Eye Disease, Ocular Hypertension, Glaucoma
- Trial name
- NCT01927406
- Testing
- Prostaglandin Analog, Timolol
- Where
- United States
- Sponsor
- Stanford University
Primary Congenital Glaucoma
Combined Nasal Goniotomy-Temporal Trabeculotomy Versus Temporal Trabeculotomy for Management of Primary Congenital Glaucoma
Combined nasal goniotomy and temporal trabeculotomy provides effective IOP control in PCG while preserving the superior conjunctiva for future filtering procedures.
- Trial name
- NCT07830017
- Testing
- combined Nasal goniotomy-Temporal trabeculotomy, Temporal trabeculotomy
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Zagazig University
Congenital Glaucoma
Comparison Between Deep Sclerectomy and Traditional Trabeculotomy & Trabeculectomy in Congenital Glaucoma
The investigators hypothesize that deep sclerectomy in congenital glaucoma is a safer procedure and may yield better results than trabeculotomy trabeculectomy approach.
- Trial name
- NCT01460017
- Testing
- Deep Sclerectomy, Combined Trab
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- King Saud University
Congenital Cataract, Aphakic Glaucoma
Prophylactic Peripheral Iridectomy Prevents Aphakic Angle-closure Glaucoma
This is a retrospective, nonrandomized comparative trial with historical control to investigate the safety and efficacy of a novel progressive grasping peripheral iridectomy (PGPI) surgical method in preventing aphakic…
- Trial name
- NCT03610295
- Testing
- PPI group, cataract extraction
- Where
- 2 sites in China
- Volunteers
- 87 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Primary Congenital Glaucoma, Developmental Glaucoma
Comparison of Surgical Treatment Options for Primary Congenital and Developmental Glaucomas
Newborn and children can be affected by two subgroups of this disease: (1) primary congenital glaucoma (PCG) or (2) developmental glaucoma (DG).
- Trial name
- STOP-Glaucoma (NCT04647929)
- Testing
- Santen PRESERFLO MicroShunt, Trabeculectomy
- Sponsor
- University of Zurich
Attention Deficit Disorder With Hyperactivity, Asthma
Study of an Intervention to Improve Problem List Accuracy and Use
The aim of this study is to identify patients with problem list gaps and intervene to correct these gaps by creating clinical decision support interventions that alert providers to likely problem list gaps and offer clinicians…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Asthma, COPD, Breast Cancer
- Trial name
- MAPLE (NCT01105923)
- Testing
- MAPLE
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Brigham and Women's Hospital
Sturge Weber Syndrome
Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS)
Sturge Weber Syndrome (SWS) is a rare disease that affects the patient's brain and causes benign (non-cancerous) tumors to grow in the brain. One of the symptoms of SWS is epilepsy. People with epilepsy have seizures.
- Trial name
- NCT01997255
- Testing
- Everolimus
- Where
- United States
- Sponsor
- Baylor College of Medicine
Congenital Glaucoma
Genetic Testing in Primary Congenital Glaucoma Patients
Primary congenital glaucoma patients and their immediate relatives will undergo complete ophthalmic examination and an interview with a geneticist. A blood sample will be drown from all participants for DNA analysis.
- Trial name
- NCT01136460
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Childhood Glaucoma
Efficacy and Safety of Topically Applied Medical Therapy for the Treatment of Pediatric Glaucoma
Objectives: The study will assess the ocular hypotensive effect of latanoprost and dorzolamide in a selected sample of patients affected by primary Pediatric Glaucoma (PG), refractory to surgical procedures.
- Trial name
- NCT01527682
- Testing
- Latanoprost, Dorzolamide
- Where
- 2 sites in Italy
- Volunteers
- 37 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Retinal Dystrophies, Retinitis Pigmentosa
Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer
Objective perimetry can better monitor visual field defects in retinal dystrophy and Glaucoma patients than conventional subjective perimetry.
- Conditions
- Retinal Dystrophies, Retinitis Pigmentosa, Glaucoma
- Trial name
- NCT02014389
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Glaucoma, Neuroprotection
Effect of Fixed Combination Citicoline Homotaurine and Pyrroloquinoline Quinone on Pattern-electroretinogram in Glaucoma
The goal of this clinical trial is to examine the effect of the fixed combination Citicoline 500 mg, Homotaurine 50 mg, Pyrroloquinoline quinone (PQQ) disodium salt (Neuprozin Mito®) on pattern electroretinogram (PERG) in…
- Trial name
- NCT06431113
- Testing
- Citicoline 500 mg plus Homotaurine 50 mg plus Pyrroloquinoline quinone (Neuprozin Mito® )
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Aniridia, Eye Abnormality
Abnormalities of the Eye's Anterior Chamber, Iris, Cornea and Lens
This study will investigate congenital or developmental eye abnormalities that affect the iris, cornea and lens, and are usually accompanied by elevated pressure within the eye.
- Conditions
- Aniridia, Eye Abnormality, Ocular Hypertension, Open Angle Glaucoma
- Trial name
- NCT00001161
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Eye Institute (NEI)
Glaucoma, Congenital Cataract
Glaucoma After Congenital Cataract Surgery
To determine the incidence of glaucoma following bilateral congenital cataract removal and estimate the associated risk factors in a large cohort to provide guidance for clinical practice.
- Trial name
- NCT04342052
- Where
- China
- Volunteers
- 351 people
- Sponsor
- Sun Yat-sen University
Iris Disease
Histopathological Examination of Iris Tissue in Buphthalmos
To revise the etiology of the primary congenital glaucoma in some infants.
- Trial name
- NCT04011878
- Testing
- Combined trabeculotomy trabeculectomy with mitomycin C
- Volunteers
- 11 people
- Sponsor
- Assiut University
Glaucoma, Age-related Macular Degeneration
Evaluation of New Head-mounted Visual Aids Among Patients With Low Vision
Glaucoma, age-related macular degeneration (AMD), retinitis pigmentosa, RP, diabetic retinopathy (DR) are the most common blinding eye diseases in the world.
- Conditions
- Glaucoma, Age-related Macular Degeneration, Retinitis Pigmentosa, Diabetic Retinopathy
- Trial name
- NCT06076720
- Testing
- New head-mounted visual aids
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University