Clinical trials: Congestion
Pelvic Pain, Varicose Veins Pelvic
Neuropeptides and Venous Pelvic Pain
Mechanisms of the development of pain in chronic venous diseases (CVD), including pelvic congestion syndrome (PCS), are studied incompletely.
- Conditions
- Pelvic Pain, Varicose Veins Pelvic, Pelvic Congestion Syndrome
- Trial name
- NVPP (NCT03921788)
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pirogov Russian National Research Medical University
Mucosal Congestion
Changes in Nasal Patency With Changes in Posture, Temperature, Humidity and Nasal Patency Seen by Acoustic Rhinometry
To study nasal physiologic responses to changes in posture, temperatures, humidity and nasal patency with acoustic rhinometry.
- Trial name
- NCT00147888
- Testing
- Acoustic rhinometry (procedure)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Healthy Participants
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Drug Effects of BMS-986308 in Healthy Participants
The purpose of this study is to evaluate the safety, tolerability, drug levels, and drug effects of BMS-986308 compared to placebo in healthy participants.
- Trial name
- NCT04763226
- Testing
- BMS-986308, Furosemide
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Emergency Department Waiting Room Congestion
Emergency Department Re-evaluation Software Pilot Study
This is a research study to determine a method in improving emergency department waiting room care by using new software program.
- Trial name
- NCT05831046
- Testing
- ED management software
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Duke University
Nasal Congestion
Bioequivalence of Single Dose Phenylephrine Extended Release Tablets and Phenylephrine HCl Immediate Release Tablets Dosed Every Four Hours (P08340)(COMPLETED)
This study will assess the food-effect bioavailability of an extended release formulation of phenylephrine HCl and its bioequivalence to the marketed immediate release phenylephrine HCl product.
- Trial name
- NCT01354418
- Testing
- Phenylephrine HCl Extended Release, Phenylephrine HCl Immediate Release
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
Spinal Stenosis
Cerebrospinal Fluid Congestion in Spinal Stenosis Patients
The investigators hypothesized spinal stenosis symptom was provocation due to cerebrospinal fluid congestion.
- Trial name
- NCT01630382
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
COPD
Acoustic and Volumetric Measurements in Order to Objectify Bronchial Congestion in Patients With Obstructive Respiratory Pathologies Within the Framework of Their Management in Respiratory Physiotherapy for Decongestion
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease defined by permanent airway obstruction. In this disease, a large part of the muscular work is taken up by breathing (fight against bronchial, parietal…
- Trial name
- MUKROBS (NCT05480163)
- Testing
- Measurement records
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Association des Réseaux Bronchiolite
Post-Op Complication, Skin Flap Necrosis
Quantifying the Venous Congestion Curve of a Tissue Oximetry Device
The purpose of this research study is to measure rate of decline and pattern of tissue oxygenation using the device, ViOptix T.Ox. ViOptix probes will be secured to the arm and hand.
- Trial name
- NCT05592145
- Testing
- ViOptix
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Nasal Congestion
Functional Magnetic Resonance Imaging (fMRI) Study of Nasal Strips in Nasal Congestion
The aim of the study is to evaluate the effect of the nasal strip (relative to the placebo strip) on the nasal passages using anatomical MRI scans and to demonstrate the effect of the strip on breathing correlated cortical…
- Trial name
- NCT02275364
- Testing
- Test strip, Nasal spray
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Heart Failure With Preserved Ejection Fraction
Exercise Lower-body Negative Pressure in Heart Failure With Preserved Ejection Fraction
The heart is a pump that must both fill and empty effectively to move blood; if it cannot move enough, heart failure may ensue. Approximately half of all adults living with heart failure have a form where the heart stiffens…
- Trial name
- NCT05582044
- Testing
- Lower-body Negative Pressure (-25 mmHg), Lower-body Negative Pressure (-15 mmHg), Lower-body Neutral Pressure (0 mmHg)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Sepsis, Sepsis and Septic Shock
Hemodynamic Venous Congestion Ultrasound (VExUS) by ICU Nurses in Sepsis Patients.
Sepsis is a serious condition where the body's immune response to infection overreacts, leading to organ damage and death. Venous congestion, a buildup of blood in the veins, can occur in sepsis and contribute to organ injury.
- Conditions
- Sepsis, Sepsis and Septic Shock, Sepsis at Intensive Care Unit, Intensive Care Nurses
- Trial name
- VEXIVAN (NCT07406750)
- Testing
- Education in performing hemodynamic diagnostic ultrasound of venous congestion, Hemodynamic diagnostic ultrasound of venous congestion
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Allergic Rhinitis
Effects of AkPharma's Calcium Glycerophosphate Nasal Spray Wash
Over 20 million Americans have allergic nasal symptoms including stuffiness, sneezing and a "runny" nose. AkPharma's Calcium Glycerophosphate used as a nasal spray wash is believed to improve these symptoms without side effects…
- Trial name
- NCT01647633
- Testing
- Calcium Glycerophosphate Nasal Spray Wash
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Drexel University
Pelvic Congestion Syndrome
Pelvic Congestion Syndrome Post Tubal Ligation Versus Salpingectomy Performed During Caesarean Section
Permanent tubal sterilization during Caesarean section is a reliable method of contraception. It is done either by bilateral tubal ligation or bilateral salpingectomy according to surgeon's preference.
- Trial name
- NCT06509425
- Testing
- salpingectomy during caesarean section, tubal ligation during caesarean section
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pelvic Venous Congestion Syndrome, Lower Limb Varicose Veins
Prevalence of Pelvic Venous Congestion Syndrome in Female Patients With Lower Extremity Varicose Veins and Its Impact on Postoperative Quality of Life Improvement Following Radiofrequency Ablation: A Single-Center Prospective Cohort Study（PCSRFStudy）
Research Summary: Impact of Pelvic Congestion Syndrome on Lower Limb Varicose Vein Treatment This prospective cohort study investigates the prevalence of Pelvic Congestion Syndrome (PCS) among women undergoing lower limb varicose…
- Conditions
- Pelvic Venous Congestion Syndrome, Lower Limb Varicose Veins, Radiofrequency Ablation
- Trial name
- NCT07680465
- Testing
- Pelvic MRI ， Radiofrequency Ablation
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Healthy Subjects
Study to Evaluate the Safety and Tolerability of Mucinex™(Guaifenesin) 600 mg Extended-Release Bi-Layer Tablets in the Treatment of Otherwise Healthy Patients With Symptoms of Cough, Thickened Mucus and Chest Congestion
This was an open label, multicentric, non-comparative, single arm prospective post marketing surveillance (PMS) study to evaluate the safety and tolerability of Mucinex™ (GGE, 600 mg ER bi-layer tablets, taken as 1200 mg BID…
- Trial name
- NCT03725085
- Testing
- Mucinex™ extended-release (SE)
- Volunteers
- 552 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser LLC
Heart Failure With Preserved Ejection Fraction (HFpEF), Atrial Fibrillation
Intracranial Pressure and a Potential Vicious Circle of Atrial Fibrillation in HFpEF
This study was designed to investigate predictors of atrial fibrillation (AF) in patients with heart failure with preserved ejection fraction (HFpEF), with a particular focus on the potential relationship between venous…
- Conditions
- Heart Failure With Preserved Ejection Fraction (HFpEF), Atrial Fibrillation, Optic Nerve Sheath Diameter, Intracranial Pressure
- Trial name
- heart failure (NCT07521293)
- Testing
- Echocardiography
- Where
- Turkey (Türkiye)
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Nonallergic Irritant Rhinitis
Intranasal Capsaicin Treatment for Non-Allergic Irritant Rhinitis
The proposed study seeks to investigate the effect of intranasal capsaicin treatment in patient with Non-allergic irritant rhinitis (NAIR), as well as evaluate optical rhinometry (ORM) as a means to quantify symptomatic…
- Trial name
- NCT02493257
- Testing
- Capsaicin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Seasonal Allergic Rhinitis
A Randomized, Double-blind, Placebo-controlled Study on the Effect of CVT-E002 in Patients With Seasonal Allergic Rhinitis
You are being asked to take part in a research study of COLD-fX, a product designed to boost the immune system. COLD-fX is an extract from the roots of North American ginseng and it may offer some benefit to people with seasonal…
- Trial name
- NCT00726401
- Testing
- COLD-fX
- Where
- 4 sites in Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Afexa Life Sciences Inc
Pelvic Congestion Syndrome
Quality of Life Questionnaire and Disease Severity Scale
There are currently no specific validated patient-centric tools for the clinical evaluation of patients with chronic pelvic venous disorders (CPVD).
- Trial name
- NCT05889000
- Testing
- questionnaire responses
- Where
- Russia
- Volunteers
- 397 people, healthy volunteers welcome
- Sponsor
- Kazan State Medical University
Allergic Rhinitis
Intranasal Steroids and Oxymetazoline in Allergic Rhinitis
We hypothesize that once daily use of oxymetazoline will not cause significant rhinitis medicamentosa and that the combination of fluticasone furoate plus oxymetazoline leads to faster relief of nasal congestion secondary to…
- Trial name
- NCT00584987
- Testing
- Fluticasone furoate, Oxymetazoline
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Chicago