Clinical trials: Congestive Heart Failure(CHF)
Systemic Sclerosis, Cardiac Diseases
Development and Prevention of Severe Heart Disease in Systemic Sclerosis
Systemic sclerosis is an orphan, multiorgan disease affecting the connective tissue of the skin and all internal organs. Cardiac involvement, mainly characterised by small intramyocardial coronary artery involvement and…
- Conditions
- Systemic Sclerosis, Cardiac Diseases, Heart Block, Cardiac Arrhythmia
- Trial name
- NCT01829126
- Where
- 11 sites in France, Germany and 4 more
- Volunteers
- 765 people
- Sponsor
- Gabriele Valentini
Heart Failure, Sudden Cardiac Death
Prospective Clinical Registry of Subcutaneous Implantable Cardioverter Defibrillator (S-ICD) (S-ICD Korea Registry)
S-ICD avoids the use intravascular leads and their associated risks, has been increasingly used for primary and secondary prevention of sudden death.
- Conditions
- Heart Failure, Sudden Cardiac Death, Ventricular Tachycardia
- Trial name
- NCT04127643
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Yonsei University
Heart Failure
A Study to Evaluate the Clinical Epidemiology of Patients With Heart Failure (HF) in India
This non-interventional, prospective, multi-centric, cross-sectional study is aimed to observe clinical practice in India in managing Heart Failure patients \& to check one year outcome in HF patients.
- Trial name
- NCT02047526
- Sponsor
- AstraZeneca
Heart Failure, Chronic Obstructive Pulmonary Disease
Effects of Remote Patient Monitoring on Chronic Disease Management
Remote patient monitoring is a potential component for the management of chronic conditions that may provide reliable and real-time physiological measurements for clinical decision support, alerting, and patient self-management.
- Conditions
- Heart Failure, Chronic Obstructive Pulmonary Disease, Chronic Kidney Disease, Uncontrolled Hypertension
- Trial name
- NCT03127852
- Testing
- Medly
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University Health Network, Toronto
Heart Failure
Effects of Individualized Cognitive Training on Cognition in Heart Failure
The SYNAPSE trial is designed to study the effects of an individualized home-based cognitive training program on cognitive functions in heart-failure patients.
- Trial name
- SYNAPSE (NCT05223426)
- Testing
- Cognitive training, Usual Care
- Where
- 2 sites in Canada
- Volunteers
- 54 people
- Sponsor
- Louis Bherer
Heart Failure, Insulin Resistance
Triglyceride-Glucose Index In Heart Failure Patients In Sohag University Hospital
study the relationship between Triglyceride glucose index and heart failure patients
- Trial name
- NCT05663632
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Heart Failure, Atrial Fibrillation
Prevalence of Subclinical Atrial Fibrillation in Heart Failure Patients and Its Relationship With Hospital Readmission
Multicentre, prospective cohort study in patients with a history of HF with preserved or reduced ejection fraction admitted to hospital with acutely decompensated HF.
- Trial name
- PROTECT-HF (NCT03541616)
- Testing
- ECG Patch, pocket ECG monitor
- Where
- 5 sites in Canada
- Volunteers
- 242 people
- Sponsor
- Population Health Research Institute
Ischemic Heart Failure, Lipids
Serum Lipids and Glucose Levels in Relation to CVD Outcomes in Patients With Ischemic Heart Failure
Current prospective cohort study is to evaluate the association between fasting lipid profiles (including total cholesterol, low density lipoprotein-cholesterol, high density lipoprotein-cholesterol, triglycerides, apolipoprotein…
- Conditions
- Ischemic Heart Failure, Lipids, Fasting Plasma Glucose, Cardiovascular Outcomes
- Trial name
- NCT03206593
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Systolic Heart Failure, Peripheral Chemoreceptor Hypersensitivity
Surgical Removal of Carotid Body in Patients With Systolic Heart Failure
The aim of the study is to determine safety, tolerability and feasibility of unilateral and bilateral carotid body excision in patients with systolic heart failure and peripheral chemoreceptor hypersensitivity.
- Trial name
- FIM (NCT01653821)
- Testing
- Carotid body excision
- Where
- Poland
- Volunteers
- 10 people
- Sponsor
- Noblewell
Mitral Regurgitation, Tricuspid Regurgitation
Early Discharge After Mitral and Tricuspid Edge-to-edge Repair: an Assessment of Feasibility and Safety
Mitral regurgitation (MR) and tricuspid regurgitation (TR) are common causes of breathlessness, fluid retention and other heart failure symptoms, which lead to reduced quality of life and frequent hospitalisation.
- Conditions
- Mitral Regurgitation, Tricuspid Regurgitation, Mitral Repair, Heart Failure
- Trial name
- EARLY-Edge (NCT06343363)
- Testing
- Early discharge protocol
- Where
- United Kingdom
- Volunteers
- 127 people
- Sponsor
- Oxford University Hospitals NHS Trust
Congestive Heart Failure
Exercise-based Cardiac Rehabilitation in Congestive Heart Failure With Coexisting Knee Osteoarthritis
Exercise-based cardiac rehabilitation (CR) has been shown to significantly improve cardiovascular health and overall well-being in patients with congestive heart failure (CHF).
- Trial name
- NCT07440914
- Testing
- Exercise Based Cardiac Rehabilitation, Controlled Group
- Where
- Pakistan
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Diastolic Heart Failure, Pulmonary Hypertension
The Regulation of Pulmonary Vascular Resistance in Patients With Heart Failure
Peripheral blood and blood following a pulmonary wedge pressure will be obtained from patients undergoing right heart catheterizations.
- Trial name
- PVR (NCT02275793)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Toledo Health Science Campus
Heart Failure, Heart Diseases
Palliative Care in Heart Failure
The primary aim of the PAL-HF trial is to assess the impact of an interdisciplinary palliative care intervention combined with usual heart failure management on health-related quality of life as measured by the Kansas City…
- Conditions
- Heart Failure, Heart Diseases, Cardiovascular Diseases
- Trial name
- PAL-HF (NCT01589601)
- Testing
- Usual heart failure care, Interdisciplinary palliative care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Duke University
Dyspnea, Coronary Artery Disease
Dyspnea in Stable Patients With Coronary Artery Disease.
Single-centre prospective study to characterize causes of dyspnea in stable patients with coronary artery disease and evaluate the possibility to determine the cause of dyspnea before in-depth examination.
- Trial name
- NCT04408612
- Testing
- Scales for assessment of symptoms
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- National Research Center for Preventive Medicine
Myocardial Fibrosis, Heart Failure
⁶⁸Ga-FAPI PET/CT for Cardiac Fibrosis in Heart Failure
Heart failure (HF) is a clinical syndrome with increasing incidence and prevalence, associated with high morbidity, mortality, and economic impact, despite therapeutic advances.
- Trial name
- MY-FAPI (NCT07296081)
- Testing
- 68Ga-FAPI PET/CT
- Where
- Portugal
- Volunteers
- 30 people
- Sponsor
- University of Coimbra
Heart Failure, Family Caregivers
Web-based Support to Caregivers in Heart Failure
Caregivers of people with heart failure experience a lack of support from health care in their caring role. They often want to become more involved in care, receive education and have the opportunity to share experiences with…
- Trial name
- NCT04885465
- Testing
- web-based psychoeducational support
- Where
- Sweden
- Volunteers
- 202 people
- Sponsor
- Linkoeping University
Obesity
Research Study to Investigate How Well Semaglutide Works in People Living With Heart Failure and Obesity
This study will look at how the participants daily life is affected by their heart failure. The study will also look at the change in participants body weight from the start to the end of the study.
- Trial name
- STEP-HFpEF (NCT04788511)
- Testing
- Semaglutide
- Where
- 146 sites in United States, Argentina and 11 more
- Volunteers
- 529 people
- Sponsor
- Novo Nordisk A/S
Heart Failure, CKD
Effect of Roxadustat on Heart Failure Patients With Anaemia and Moderate-to-Severe Chronic Kidney Disease
Previous clinical observations of potential benefit from Roxadustat in this complex patient population prompted this investigation Therefore, the investigators designed this retrospective, observational study to thoroughly…
- Conditions
- Heart Failure, CKD, Anemia
- Trial name
- NCT07268807
- Testing
- Roxadustat
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Zhongda Hospital
The Focus is to Investigate Effects of a Disease Management Intervention for Patients With Congestive Heart Failure
A Disease Management Study Targeted to Reduce Health Care Utilization for Patients With Congestive Heart Failure
The aim of this study is to determine whether a nurse-managed telephone-based disease-management intervention can reduce healthcare utilization and improve self-assessed health status in patients with congestive heart failure.
- Trial name
- NCT02251899
- Testing
- Disease-Management intervention
- Where
- Sweden
- Volunteers
- 10,000 people
- Sponsor
- Health Navigator
Congestive Heart Failure, Low Cardiac Output
Losartan in Decompensated Heart Failure
The dual blockade of the renin-angiotensin-aldosterone system with an angiotensin-converting enzyme inhibitor and an angiotensin-receptor blocker used together in heart failure patients has been demonstrated to be beneficial.
- Trial name
- NCT01857999
- Testing
- Losartan
- Where
- Brazil
- Volunteers
- 21 people
- Sponsor
- InCor Heart Institute
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