Clinical trials: Congestive Heart Failure(CHF)
Chronic Heart Failure, Fear of Movement (Fear of Physical Activity)
Fear of Activity in Situations (FActS) - Study 2016
The aim of the study is to evaluate the psychometric properties of the newly developed Fear of Activity in Situations - Heart Failure (FActS-HF 15) scale.
- Trial name
- NCT02898246
- Where
- 6 sites in Germany
- Volunteers
- 187 people
- Sponsor
- University of Trier
Heart Failure, Congestive
Evaluation of a Nurse Case Management Model for Chronic Heart Failure
Despite established clinical practice guidelines, wide variations exist in the care of chronic heart failure (CHF) patients in Veterans Health Administration.
- Trial name
- CHF ENCORE (NCT00105703)
- Testing
- Case management using advanced nurse practitioners
- Where
- 4 sites in United States
- Volunteers
- 969 people
- Sponsor
- US Department of Veterans Affairs
Infection, Heart Failure
Remote Physician Care for Home Hospital Patients
This study examines the implications of providing remote physician care to home hospitalized patients compared to usual home hospital care with in-person/in-home physician visits.
- Conditions
- Infection, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT04080570
- Testing
- Remote Visit
- Where
- 2 sites in United States
- Volunteers
- 172 people
- Sponsor
- Brigham and Women's Hospital
Hyperkalemia
Patiromer for the Management of Hyperkalemia in Subjects Receiving RAASi Medications for the Treatment of Heart Failure (DIAMOND)
The purpose of this study is to assess the effects of patiromer compared with placebo on serum K+ in HF patients.
- Trial name
- DIAMOND (NCT03888066)
- Testing
- Patiromer
- Where
- 415 sites in United States, Argentina and 19 more
- Volunteers
- 1,195 people
- Sponsor
- Vifor Pharma, Inc.
Heart Failure
The Effect of Omega-3 Polyunsaturated Fatty Acids in Congestive Heart Failure
A diet rich in Omega-3 (fish oil) reduces plasma triglycerides and the risk for ischemic heart disease. Recently, a large trial evaluating treatment with Omega 3 in heart failure patients suggested that omega 3 may lower the risk…
- Trial name
- NCT00944229
- Testing
- LOVAZA (Omega-3)
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Columbia University
Heart Failure, Hyponatremia
The Effect of Fluid Restriction in Congestive Heart Failure Complicated With Hyponatremia
The purpose of this study is to determine the effect of fluid restriction and the neurohormonal mechanisms in the development of hyponatremia in patients with congestive heart failure and hyponatremia.
- Trial name
- Decongest (NCT01748331)
- Testing
- Fluid restriction
- Where
- 2 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Finn Gustafsson
Heart Failure
Empagliflozin on Patients With Preserved Heart Failure
The proposed research in this application will investigate the effect of empagliflozin on cardiac remodeling in patients with heart failure with preserved ejection fraction.
- Trial name
- NCT07112274
- Testing
- Empagliflozin 10 MG
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Damanhour University
Heart Failure
Artificial Intelligence (AI) Analysis of Synchronized Phonocardiography (PCG) and Electrocardiogram(ECG)
The diagnosis of depressed left ventricular ejection fraction (dLVEF) (EF<50%) depends on golden standard ultrasound cardiography (UCG).
- Trial name
- NCT06009718
- Where
- 3 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Ruijin Hospital
Chronic Heart Failure
Muscle Afferent Feedback Effects in Patients With Heart Failure
The purpose of the study is to find out more about the mechanism by which neural feedback from the working muscle affects the development of central fatigue during exercise.
- Trial name
- NCT01919918
- Testing
- Muscle Contraction with Metabolite Solution Administration
- Where
- 2 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Utah
Congestive Heart Failure, Chronic Kidney Diseases
Within Subject Variability Study of ER Torsemide 20 mg Tablet in Healthy Subjects
The study will evaluate the within-subject variability of 20mg ER torsemide as compared to 20mg IR torsemide (Demadex) in fully replicate double-crossover trial in healthy volunteers, who are consuming a high-salt diet (300…
- Trial name
- NCT03214874
- Testing
- Demadex 20mg Tablet, ER Torsemide 20mg Tablet
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sarfez Pharmaceuticals, Inc.
Mitral Regurgitation, Heart Failure
Remote Monitoring of Patients With Functional Mitral Regurgitation Undergoing Mitraclip Transcatheter Repair
HERMES is a pilot study which aims at exploring the impact of remote monitoring in patients with severe functional mitral regurgitation undergoing transcatheter mitral valve edge-to-edge repair with the Mitraclip system.
- Trial name
- HERMES (NCT02698150)
- Testing
- HERMES tablet
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- Azienda Ospedaliero, Ferrarotto Alessi
Heart Failure With Preserved Ejection Fraction, Microvascular Angina
Neuregulin-1 in Patient With Different Forms of Cardiovascular Diseases: a Pilot Study
This is an observational study of Neuregulin-1 (NRG-1) plasma levels in patients with different forms of cardiovascular disease including microvascular angina (MVA), heart failure with preserved ejection fraction (HFpEF), as well…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Microvascular Angina, Pulmonary Hypertension, Heart Failure With Reduced Ejection Fraction
- Trial name
- NRG-1-CVDs (NCT04391491)
- Testing
- Neuregulin-1β level in plasma
- Where
- Russia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Heart Failure
Trial of Education and Compliance in Heart Dysfunction (TEACH)
The emphasis of this grant is to investigate ways to educate patients, not only to improve their knowledge about medications and diet that are important for better outcomes in heart failure, but also to try to understand how…
- Trial name
- NCT00211289
- Testing
- Education by community pharmacist
- Where
- 2 sites in Canada
- Volunteers
- 383 people
- Sponsor
- London Health Sciences Centre
Heart Failure With Mid Range Ejection Fraction
Outcome of Discharged HFmrEF Patients
This study aimed to define the independent risk factors related cardiac events (cardiac death or heart failure-related hospitalization) among heart failure with mildly reduced ejection fraction (HFmrEF) patients who discharged…
- Trial name
- OUDI-HF (NCT05240118)
- Volunteers
- 1,693 people
- Sponsor
- Xiangtan Central Hospital
Congestive Heart Failure
Estimated Physical Activity of Congestive Heart Failure Patients by a Physical Activity Questionnaire
The treatment and follow-up of congestive heart failure (CHF) represents a major part of France's health expenses. The beneficial effects of cardiac rehabilitation is well established, especially regarding the reduction of…
- Trial name
- H2OBis (NCT00676390)
- Testing
- doubly labelled water and questionnaire
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Heart Failure, Cardiomyopathies
Multimodal Physiologic State Intelligence Study
The OMNIPHYS study will investigate whether multimodal ultrasound and other routinely collected clinical and physiologic data can be combined with artificial intelligence to characterize changes in a person's physiologic state…
- Conditions
- Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute
- Trial name
- OMNIPHYS (NCT07814118)
- Testing
- OMNIPHYS Multimodal Ultrasound Imaging System
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Heart Failure
Proof-of-Concept Study of Heart Habits Application for Patients With Heart Failure
This study assesses the ability of ambulatory patients with heart failure (HF) to use a smartphone application created for the management of patients with chronic HF.
- Trial name
- NCT03238729
- Testing
- Heart Failure Education and Management App, Heart Failure Literature
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Jana Care
Heart Failure
Mechanism and Effects of Manipulating Chloride Homeostasis in Acute Heart Failure
The purpose of this study is to understand the effects of chloride supplementation on volume-overloaded acute heart failure patients concomitantly treated with IV diuretics.
- Trial name
- NCT03446651
- Testing
- Lysine Chloride
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Congestive Heart Failure, Diabetes
Evaluation of Programs of Coordinated Care and Disease Management
This is a Congressionally mandated study. In the original study, 16 demonstration programs provided care coordination services to beneficiaries with chronic illness in Medicare's fee-for-service program.
- Conditions
- Congestive Heart Failure, Diabetes, Coronary Artery Disease, Chronic Obstructive Pulmonary Disease
- Trial name
- Coca (NCT00627029)
- Testing
- Care Coordination
- Where
- 15 sites in United States
- Volunteers
- 18,277 people
- Sponsor
- Mathematica Policy Research, Inc.
Heart Failure, Remote Consultation, Teleconsultation
Comparison Between a Robotic Tele-echo-cardiography Technique and a Standard Echocardiography in the Management of Heart Failure in the Guadeloupe Archipelago Between the University Hospital of Guadeloupe and the Marie-Galante Hospital
The TERdeblue-S study is a feasibility study of robotic remote echocardiography, not only in terms of technology but also in terms of its integration into a telemedicine system to improve access to the heart failure management…
- Conditions
- Heart Failure, Remote Consultation, Teleconsultation, Echocardiography, Doppler
- Trial name
- TER de blueS (NCT07265986)
- Testing
- in situ echocardiography (EIS), two-dimensional remote echocardiography (TER)
- Where
- 3 sites in Guadeloupe
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
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