Clinical trials: Congestive Heart Failure, completed
Heart Failure, Heart-assist Devices
PCORI-1310-06998 Trial of a Decision Support Intervention for Patients and Caregivers Offered Destination Therapy Heart Assist Device
The left ventricular assist device (LVAD) is growing rapidly among people dying from end-stage heart failure who are unable to get a heart transplant.
- Trial name
- DECIDE-LVAD (NCT02344576)
- Testing
- DT LVAD Decision Support Intervention
- Where
- 6 sites in United States
- Volunteers
- 445 people
- Sponsor
- University of Colorado, Denver
Heart Failure, Coronary Artery Disease
3/7 Resistance Training Method in Cardiac Rehabilitation
Aim of the clinical monocentric study is to assess the resistance training exercise intervention in patients with Heart Failure with reduced Ejection Fraction (HFrEF) and coronary artery disease that will best improve peak oxygen…
- Trial name
- NCT05696990
- Testing
- 3/7 Resistance Training Method, 3X9 Resistance Training Method
- Where
- Belgium
- Volunteers
- 112 people
- Sponsor
- Université Libre de Bruxelles
Hypertension
Sodium Excretion of LCZ696 in Patients With Hypertension; Heart Failure and Healthy Volunteers
Assess mechanism of action of LCZ696 related to sodium excretion.
- Trial name
- NCT01353508
- Testing
- LCZ696, Valsartan
- Where
- Russia
- Volunteers
- 32 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Heart Failure
Handled Echocardiography and Chronic Heart Failure
The aim of the study is to compare two different home monitoring care programs in patients with chronic heart failure in functional class NYHA III, one of them based on clinical and electrocardiographic evaluations, the other one…
- Trial name
- NCT01365325
- Testing
- handled echocardiography in home monitoring program, ecg and clinical evaluation in home monitoring program
- Where
- Italy
- Volunteers
- 118 people
- Sponsor
- Federico II University
Heart Failure
MADIT-CRT LONG-TERM INTERNATIONAL FOLLOW-UP REGISTRY - EUROPE
The registry is designed to determine the long-term mortality and morbidity benefit as a result of Cardiac Resynchronization Therapy with Defibrillation (CRT-D) vs.
- Trial name
- NCT02060110
- Testing
- Patients that were randomized to the the cardiac resynchronization therapy with defibrillation (CRT-D) device for the study, MADIT-CRT ICD ONLY ARM
- Where
- Israel
- Volunteers
- 447 people
- Sponsor
- Sheba Medical Center
Congestive Heart Failure
AC6 Gene Transfer for CHF
This research study is designed to determine: 1) whether gene transfer using an agent called Ad5.hAC6 (adenovirus-5 encoding human adenylyl cyclase type 6) can be given safely to patients with congestive heart failure (CHF) and…
- Trial name
- NCT00787059
- Testing
- Ad5.hAC6, Sucrose (3%)
- Where
- 7 sites in United States
- Volunteers
- 56 people
- Sponsor
- Hammond, H. Kirk, M.D.
Chronic Heart Failure
A Study of Valsartan Administered Once Daily Versus Twice Daily, in Patients With Stable, Chronic Heart Failure
This study will evaluate the tolerability and safety of valsartan in patients with stable, chronic heart failure (NYHA Class ll-lll).
- Trial name
- NCT00294086
- Testing
- valsartan 160 mg, valsartan 160 mg BID
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Novartis
Hyperkalemia
Patiromer for the Management of Hyperkalemia in Subjects Receiving RAASi Medications for the Treatment of Heart Failure (DIAMOND)
The purpose of this study is to assess the effects of patiromer compared with placebo on serum K+ in HF patients.
- Trial name
- DIAMOND (NCT03888066)
- Testing
- Patiromer
- Where
- 415 sites in United States, Argentina and 19 more
- Volunteers
- 1,195 people
- Sponsor
- Vifor Pharma, Inc.
HIV/AIDS, Heart Failure With Preserved Ejection Fraction
The ENCHANTMENT HIV Study
Persons with HIV, even those well-treated, are at increased risk for heart disease when compared to the general population. Two hormones called aldosterone and brain natriuretic peptide (BNP), which have been shown to be abnormal…
- Trial name
- NCT04153136
- Testing
- Sacubitril-Valsartan 49-51Mg Oral Tablet
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Massachusetts General Hospital
Heart Failure
Data Collection Study of Wedge Pressure Data in Patients With CRT-D Devices
zWedge is a clinical feasibility IDE study. The objective is to characterize the relationship between intra-thoracic impedance measurements obtained from a CRT-D device and pulmonary capillary wedge pressure (PCWP) measured via a…
- Trial name
- zWedge (NCT00811551)
- Testing
- CRT-D (Intra-thoracic Impedance Monitoring)
- Where
- 7 sites in United States
- Volunteers
- 22 people
- Sponsor
- Abbott Medical Devices
Chronic Heart Failure With Reduced Ejection Fraction
An Observational Study, Called VERI-China, to Learn More About How Well Vericiguat Works and How Safe it is in Real-world Setting in People With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) in China
This is an observational study in which data from people in China with chronic heart failure with reduced ejection fraction (HFrEF) who will be receiving vericiguat treatment are collected.
- Trial name
- VERI-China (NCT05728502)
- Testing
- Vericiguat (Verquvo, BAY1021189), Standard of Care (SoC)
- Where
- China
- Volunteers
- 2,400 people
- Sponsor
- Bayer
Heart Failure
Cardiac Resynchronisation Study
This study aims to investigate the effect of a pacemaker device used in heart failure patients which is called Cardiac Resynchronisation Therapy (CRT).
- Trial name
- NCT01213537
- Where
- United Kingdom
- Volunteers
- 182 people
- Sponsor
- Imperial College London
Heart Failure
Identification of Heart Failure Patients by Seismocardiography
The aim of the current study is to develop and validate an algorithm based on seismocardiography recordings to detect heart failure. Echocardiography will be used as the golden standard for defining patients with heart failure.
- Trial name
- SCG-HF (NCT03656354)
- Testing
- Seismocardiography
- Where
- 2 sites in Denmark
- Volunteers
- 219 people
- Sponsor
- Acarix
Heart Failure, Diastolic
Exercise Pulmonary Transit Time
The study seeks to measure pulmonary transit time via contrast-echocardiography before and after exercise.
- Trial name
- NCT04336995
- Testing
- contrast echocardiography
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Heart Failure
Evaluation of the Effect of Animated Video-Assisted Nutrition Education on Heart Failure Patients
This randomized controlled trial aims to evaluate the effect of animation video-supported nutrition education on dietary behaviors, symptom severity, and quality of life in patients with heart failure.
- Trial name
- NCT07305272
- Testing
- Animation Video-Supported Nutrition Education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Tokat Gaziosmanpasa University
Diabetes, Hypertension
Quality IQ Patient Simulation Physician Practice Measurement and Engagement
This study will test the quality of physician care decisions using a patient-simulation based measurement and feedback approach that combines multiple-choice care decisions with real-time, personalized scoring and feedback.
- Conditions
- Diabetes, Hypertension, Depression, Osteoarthritis
- Trial name
- Q-IQ (NCT03800901)
- Testing
- Continuing Medical Education, Quality IQ Patient Simulations
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Covid19, Acute Cor Pulmonale
Cardiac Performance in Mechanically Ventilated COVID-19 Patients
Although COVID-19 affects primarily the respiratory system, several studies have shown evidence of cardiovascular alterations. Increased troponin levels were observed in a significant proportion of patients and this alteration…
- Conditions
- Covid19, Acute Cor Pulmonale, Cardiac Failure
- Trial name
- NCT04628195
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Heart Failure, Copd
The DIVERT-CARE (Collaboration Action Research & Evaluation) Trial
Rationale: In Canada, home care clients are a large and expanding subgroup of medically complex older adults with relatively poor access to effective chronic disease management.
- Trial name
- DIVERT-CARE (NCT03012256)
- Testing
- Cardio-respiratory management model
- Where
- 3 sites in Canada
- Volunteers
- 896 people
- Sponsor
- McMaster University
Heart Failure
Mutton Heart Failure Food is Medicine Pilot
Study subjects with heart failure will receive either pre-prepared, home-delivered DASH/SRD-compliant meals incorporating local Navajo traditional foods or usual care for 30 days (14 meals weekly).
- Trial name
- Mutton-HF (NCT06675331)
- Testing
- Medically Tailored Meal Program with Traditional Navajo Foods
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Heart Failure
Role of Sacubitril/Valsartan in Improving Provider Performance in Managing Heart Failure Under Medicare Alternative Payment Models
This study evaluated the association between sacubitril/valsartan utilization and HF patients' Part A \& B expenditures within the reimbursement framework of BPCI and MSSP, and identified BPCI/MSSP participants with the greatest…
- Trial name
- NCT05096039
- Testing
- Sacubitril/valsartan, ACEI or ARB and no sacubitril/valsartan
- Where
- United States
- Volunteers
- 1,614,719 people
- Sponsor
- Novartis Pharmaceuticals
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