Clinical trials: Congestive Heart Failure, completed
Chronic Kidney Disease 5D, Heart Failure
Cardio-fistular Recirculation in Patients With Chronic Heart Failure and Preserved Left Ventricle Ejection Fraction
This is a single-arm cohort study aimed to evaluate change of arteriovenous fistula volume blood flow / cardiac output ratio in patients with chronic heart failure (NYHA I-II classes) and with preserved ejection fraction as a…
- Conditions
- Chronic Kidney Disease 5D, Heart Failure, Heart Failure NYHA Class I, Heart Failure NYHA Class II
- Trial name
- NCT06394986
- Testing
- Hemodialysis session
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)
Heart Failure With or Without CRT-P/D
Evaluation of Exercise Tolerance and Cardiac Output in Patients With Heart Failure After Intervention of Rehabilitation Program
Home-based rehabilitation programs have not been widely few been studied and the training effects are not unclear. This study evaluates the beneficial effects of home-based cardiac rehabilitation on quality of medical care in…
- Trial name
- NCT02928783
- Testing
- Home-based cardiac rehabilitation
- Volunteers
- 37 people
- Sponsor
- Taichung Veterans General Hospital
Heart Failure; With Decompensation, Cardiorenal Syndrome
The Aortix CRS Pilot Study
The Aortix CRS Pilot Study: An Evaluation of the Safety and Performance of the Aortix System for Intra-Aortic Mechanical Circulatory Support in Patients with Cardiorenal Syndrome
- Conditions
- Heart Failure; With Decompensation, Cardiorenal Syndrome, Cardio-Renal Syndrome, Heart Failure
- Trial name
- NCT04145635
- Testing
- Aortix System
- Where
- 19 sites in United States, Australia
- Volunteers
- 21 people
- Sponsor
- Procyrion
Heart Failure, Diastolic
Mechanisms and Management of Exercise Intolerance in Older Heart Failure Patients
Heart failure with preserved ejection fraction (HFpEF) is the fastest growing form of heart failure with a high morbidity and mortality rate, and is associated with severe exercise intolerance.
- Trial name
- NCT03111017
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Cardiac Failure
Tomography Positron Emission Assessment of the Impact of Cardiac Rehabilitation on Coronary Endothelial Function in Cardiac Failure
In patients with heart failure, the drive to the effort has demonstrated its safety and its interest. Patients with heart failure, endothelium-dependent peripheral vasodilatation is impaired by decreased activity of endothelial…
- Trial name
- TEP-READ (NCT02524574)
- Testing
- cardiac Rehabilitation, Tomography Positron Emission
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Caen
Myocarditis, Myocardial Failure
Monitoring Drug-induced Myocarditis (CardiTOX)
Several drugs and chemotherapies seem to induce myocarditis. This study investigates reports of myocarditis, including the International classification of disease ICD-10 for treatments in the World Health Organization (WHO)…
- Conditions
- Myocarditis, Myocardial Failure, Myocardial Dysfunction
- Trial name
- CardiTOX (NCT03855982)
- Testing
- Drug inducing myocarditis
- Where
- France
- Volunteers
- 6,000 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Heart Failure
A Pharmacogenomic Study of Candesartan in Heart Failure
The purpose of this study is to evaluate the impact of genetic variations on the response to candesartan in patients with heart failure who are already treated with an ACE inhibitor.
- Trial name
- NCT00400582
- Testing
- Candesartan up to 32 mg daily
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Montreal Heart Institute
Heart Failure, Coronary Artery Disease
Same Day Discharge (SDD) After Implantable Cardioverter Defibrillator (ICD) Implant
The purpose of this study is to determine whether it is safe to send patients home from the hospital on the same day following an implantable cardioverter defibrillator (ICD) implant.
- Trial name
- SDD for ICD (NCT01993862)
- Testing
- Same Day Discharge
- Where
- 28 sites in United States
- Volunteers
- 266 people
- Sponsor
- Abbott Medical Devices
Acute Heart Failure
Gulf Acute Heart Failure Registry
The Gulf Heart Association (GHA) sponsored Gulf acute heart failure registry (Gulf CARE)is a multinational , multicentre, prospective, observational, hospital-based registry of patients with acute heart failure(AHF) with 3 month…
- Trial name
- GulfCARE (NCT01467973)
- Where
- Oman
- Volunteers
- 5,005 people
- Sponsor
- Gulf Heart Association
Cardiomyopathy, Congestive Heart Failure
AiDing Diuresis wIth Tolvaptan (ADD-IT)
The purpose of this study is to test the use of tolvaptan (commercial name Samsca) when given in addition to intravenous (IV) diuretics early during an episode of acute heart failure.
- Trial name
- ADD-IT (NCT02646540)
- Testing
- Tolvaptan 30 mg + IV Diuretics, Metolazone 5 mg + IV Diuretics, 2.5 times the Diuretics Dose
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Emory University
Heart Failure
Coping Effectiveness Training in Patients With Chronic Heart Failure
The purpose of the present study is to develop, implement and evaluate a stress management program aiming to improve emotional well-being, health-related quality of life and to reduce readmission to hospital in patients with…
- Trial name
- NCT02463903
- Testing
- Coping Effectiveness Training (CET)
- Volunteers
- 103 people
- Sponsor
- Karolinska Institutet
Cardiac Disease, Heart Failure
Retrospective Experience Of CIED Implantation
The objective of this study is to retrospectively gather information on patients who underwent a CIED procedure with either a CanGaroo Envelope, TYRX Envelope, or no envelope.
- Conditions
- Cardiac Disease, Heart Failure, Coronary Artery Disease
- Trial name
- NCT04351269
- Testing
- CanGaroo Envelope, TYRX Envelope
- Where
- United States
- Volunteers
- 597 people
- Sponsor
- Elutia Inc.
Sleep Apnea
Mapping for Acute Transvenous Phrenic Nerve Stimulation Study
The Mapping for Transvenous Phrenic Nerve Stimulation Study (MAPS) is being conducted to evaluate the feasibility of transvascular stimulation of phrenic nerves via an electrophysiology (EP) catheter advanced into the great veins.
- Trial name
- MAPs (NCT01981590)
- Testing
- Stimulating the phrenic nerve intravenously using high frequency electrical pulses using an EP catheter connected to external pulse stimulator.
- Where
- 2 sites in Netherlands, Sweden
- Volunteers
- 15 people
- Sponsor
- Medtronic BRC
Heart Failure, Cardiomyopathies
The Impact of Zinc Supplementation on Left Ventricular Function in Nonischemic Cardiomyopathy
Heart failure affects over 5.3 million Americans and, while other cardiovascular diseases have enjoyed a reduction in mortality rates over the last decade, the mortality from heart failure continues to rise[1].
- Trial name
- NCT00696410
- Testing
- Zinc Acetate
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Michigan
Heart Failure
Identification of the Pericardiophrenic Vein During Cardiac Device Implant Procedures to Prevent Extracardiac Stimulation
The primary goal of this study is to develop techniques to identify the course of the phrenic nerve in patients already undergoing cardiac resynchronization therapy (CRT) implantation or candidates for future CRT devices…
- Trial name
- IDPV-003 (NCT01008670)
- Where
- 13 sites in United States, Germany and 3 more
- Volunteers
- 120 people
- Sponsor
- Respicardia, Inc.
Heart Failure, Heart Decompensation
Multiparametric Assessment of Cardiac Congestion in Outpatient Worsening Heart Failure
This observational study is conducted to assess the evolution of multiple markers of congestion over 4 weeks after a worsening heart failure (WHF) event treated in an outpatient unit
- Trial name
- EVOLUTION (NCT05747820)
- Testing
- Observational study
- Where
- 4 sites in Armenia, Bosnia and Herzegovina
- Volunteers
- 42 people
- Sponsor
- Corteria Pharmaceuticals
Pneumonia, Diabetes
Social Incentives to Increase Mobility
This study aims to assess the effectiveness of a social incentive-based gamification intervention to increase physical activity in the 3 months after hospital discharge.
- Conditions
- Pneumonia, Diabetes, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
- Trial name
- MOVE IT (NCT03321279)
- Testing
- Social Incentive
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- University of Pennsylvania
Chronic Obstructive Pulmonary Disease, Chronic Heart Failure
The 7-Visit Transition of Care Hospital to Home Intervention: A Pilot Study
New approaches to care transitions must deploy a longer-term and more intensive program that provide an array of services that address underlying social determinants of health (e.g.
- Trial name
- NCT04955405
- Testing
- The seven visit telemedicine protocol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Systolic Heart Failure, Dysynchrony
Imaging Study of Allocation of Pacing Targets in Cardiac Resynchronization Therapy
This randomized controlled trial will assess a cardiac MRI derived 4D digital cardiac model to optimized left and right ventricular lead delivery to improve response to cardiac resynchronization therapy.
- Conditions
- Systolic Heart Failure, Dysynchrony, Image Guidance, Digital Twins
- Trial name
- NCT01640769
- Testing
- 4D Model guided delivery of cardiac pacing leads, Standard CRT lead delivery
- Where
- 5 sites in Canada
- Volunteers
- 210 people
- Sponsor
- Libin Cardiovascular Institute of Alberta
Congestive Heart Failure (CHF)
Prospective Evaluation of the StatusFirst™ CHF NT-proBNP Device in Human Whole Blood and Plasma Samples
The primary objective of the study is to establish the correlation between NT-proBNP measurements in fresh human whole blood samples and those in plasma samples from the same study subjects, where said samples are collected in…
- Trial name
- WB-13 (NCT00734045)
- Where
- 2 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Nanogen, Inc.
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