Clinical trials: Congestive Heart Failure, completed
Heart Failure
Mobile Integrated Health in Heart Failure
The purpose of this study is to compare how two different types of care after a hospitalization reduce hospital readmissions and symptom burden.
- Trial name
- NCT04662541
- Testing
- Mobile Integrated Health (MIH), Transitions of care coordinator (TOCC)
- Where
- 3 sites in United States
- Volunteers
- 2,005 people
- Sponsor
- Columbia University
Heart Failure
Fluid Restriction in Heart Failure Versus Liberal Fluid Uptake
Multi-centre open-label 1:1 randomized clinical trial in chronic heart failure patients on the effect of fluid restriction versus liberal fluid intake on quality of life.
- Trial name
- FRESH-UP (NCT04551729)
- Testing
- Lifestyle advice for liberal fluid intake
- Where
- 8 sites in Netherlands
- Volunteers
- 504 people
- Sponsor
- Radboud University Medical Center
Chronic Heart Failure
Prediction of Outcomes in Patients With Chronic Heart Failure Based on Tissue Raman Spectroscopy
Chronic heart failure (CHF) is a syndrome complicating heart disease, the prevalence of which has reached epidemic levels. According to global statistics the most common causes of CHF are coronary heart disease (CHD): 26.5%…
- Trial name
- PROMETHEUS (NCT06393595)
- Testing
- surface enhanced Raman Spectroscopy
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Samara State Medical University
Coronary Artery Disease With Need for Bypass Surgery, Myocardial Ischemia, Angina Pectoris
Bypass Surgery and CD133 Marrow Cell Injection for Treatment of Ischemic Heart Failure
Cell transplantation for treatment of heart failure is a novel field of translational research that offers the perspective of developing curative approaches by regenerating or "rejuvenating" lost and/or diseased myocardium and…
- Conditions
- Coronary Artery Disease With Need for Bypass Surgery, Myocardial Ischemia, Angina Pectoris, Congestive Heart Failure, Previous Myocardial Infarction
- Trial name
- Cardio133 (NCT00462774)
- Testing
- Intramyocardial injection of autologous CD133+ marrow cells
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- German Heart Institute
Arrhythmia, Heart Failure
Model 4968 CAPTURE EPI® STERIOD-ELUTING BIPOLAR EPICARDIAL PACING LEAD Post-approval Study
The Medtronic CapSure Epi Lead Post-approval Study will assess long-term safety of the 4968 lead. This study is part of the Medtronic System Longevity Study.
- Trial name
- 4968 (NCT01076361)
- Where
- 106 sites in United States, Australia and 12 more
- Volunteers
- 370 people
- Sponsor
- Medtronic
Multiple Chronic Diseases Among Diabetes Mellitus, Chronic Obstructive Pulmonary Diseases and Heart Failure
Life-long Monitoring of Frail Patients With Chronic Diseases
The purpose of this study is to evaluate whether telemonitoring of frail patients with chronic diseases produces benefits in terms of reduced readmissions, improved health related quality of life, and improved health status.
- Trial name
- NCT01608932
- Testing
- Telemonitoring for frail patients with chronic diseases
- Where
- 7 sites in Italy
- Volunteers
- 152 people
- Sponsor
- Regione Veneto
Congestive Heart Failure, Cardiomyopathy
Cardiac Hormone Replacement With Brain Natriuretic Peptide (BNP) in Heart Failure
The purpose of this study is to determine the effects of subcutaneous injection of Human BNP (nesiritide), a hormone produced by the heart, on the pumping ability of the heart, kidney function, and hormonal function in persons…
- Trial name
- SubqBNP (NCT00252187)
- Testing
- B-type Natriuretic Peptide (BNP)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Horng Chen
Physical Inactivity, Heart Failure
Heart Failure Activity Coach Study
An application (app) called the activity coach will be tested to see if it can increase physical activity and decrease sedentary behaviuor, as well as increase quality of life and lead to personal goal attainment in physically…
- Trial name
- HEALTHY (NCT05235763)
- Testing
- activity coach
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- CareLigo AB
Heart Failure With Reduced Ejection Fraction (HF-rEF)
Study of Efficacy and Safety of LCZ696 in Japanese Patients With Chronic Heart Failure and Reduced Ejection Fraction
The purpose of this study was to assess the effect of LCZ696 at a target dose of 200 mg b.i.d. compared to enalapril 10 mg b.i.d., in addition to the background heart failure (HF) treatment, on delaying time to first occurrence…
- Trial name
- PARALLEL-HF (NCT02468232)
- Testing
- LCZ696, Enalapril
- Where
- 49 sites in Japan
- Volunteers
- 225 people
- Sponsor
- Novartis Pharmaceuticals
Mitral Regurgitation, Tricuspid Regurgitation
Early Discharge After Mitral and Tricuspid Edge-to-edge Repair: an Assessment of Feasibility and Safety
Mitral regurgitation (MR) and tricuspid regurgitation (TR) are common causes of breathlessness, fluid retention and other heart failure symptoms, which lead to reduced quality of life and frequent hospitalisation.
- Conditions
- Mitral Regurgitation, Tricuspid Regurgitation, Mitral Repair, Heart Failure
- Trial name
- EARLY-Edge (NCT06343363)
- Testing
- Early discharge protocol
- Where
- United Kingdom
- Volunteers
- 127 people
- Sponsor
- Oxford University Hospitals NHS Trust
Chronic Ischemic Symptomatic Heart Failure
Intracoronary Injection of Autologous Bone Marrow Cells in Patients With Chronic Heart Failure: Five Years Follow up
The study aim is to evaluate the long term outcome of intra-coronary autologous bone marrow (BM) transplantation in patients with severe ischemic cardiomyopathy without the option for revascularization.
- Trial name
- NCT00933621
- Testing
- Autologous bone marrow intracoronary infusion
- Where
- Israel
- Volunteers
- 8 people
- Sponsor
- Assaf-Harofeh Medical Center
Heart Failure NYHA Class II
Nutritional Therapy Interventions in Heart Failure
The investigators will examine the effects of 12-weeks of nutritional interventions in older participants who have a symptom of mild to moderate heart failure.
- Trial name
- NCT03424265
- Testing
- EAA mixture
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Arkansas
Kidney Disease, Chronic, Heart Failure
New Heart Failure Biomarkers in Early Stage Chronic Kidney Disease-Mineral and Bone Disorder
the objective of this study is to : -Determinate wether the circulating levels of iFGF23 and klotho can be a predictor biomarker of HF in patients with CKD-MBD.
- Trial name
- CKD-MBD-HF (NCT03307707)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Pr. Semir Nouira
Chronic Heart Failure
The IMPULSE Study: Pilot
Continuous-flow (CF) left ventricular assist devices (LVADs) are an important tool in the treatment of end-stage heart failure, affording patients significantly improved quantity and quality of life.
- Trial name
- IMPULSE (NCT02044471)
- Testing
- Remote Ischemic Conditioning (using Sphygmomanometer)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine
Heart Failure
"A Nurse-led Motivational Interviewing Tailored Intervention for Improving Self Care Behaviours and Health Outcomes in Heart Failure Patients in Oman
This is a pilot randomized clinical trial that have employed a motivational interviewing intervention to enhance self-care in heart failure patients.
- Trial name
- MITI (NCT07721909)
- Testing
- Motivational interviewing, Standard Care (Treatment as Usual)
- Where
- Oman
- Volunteers
- 60 people
- Sponsor
- Sultan Qaboos University
Heart Failure
Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device (LVAD) and Medical Management
The purpose of this study is to evaluate and compare the effectiveness of the HeartMate II (HM II) Left Ventricular Assist Device (LVAD) support versus OMM in ambulatory NYHA Class IIIB/IV heart failure patients who are not…
- Trial name
- ROADMAP (NCT01452802)
- Testing
- HM II (HeartMate II LVAD), OMM (Optimal Medical Management)
- Where
- 52 sites in United States
- Volunteers
- 200 people
- Sponsor
- Abbott Medical Devices
Heart Failure, Chagas Disease
Effect of Ganglionar Electrical Stimulation on Central Arterial Pressure
This study will evaluate the applications of ganglionar electrical stimulation in patients with Chagas Disease and Ischemic Heart Failure patients.
- Trial name
- NCT01874795
- Testing
- TENS
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Heart Failure With Preserved Ejection Fraction
Efficacy of an m-Health Cardiac Rehabilitation Program in Heart Failure With Preserved Ejection Fraction
Heart failure (HF) portends substantial morbidity, mortality, and health care costs in the United States and the prevalence of heart failure with preserved ejection fraction (HFpEF) relative to HF with reduced ejection fraction…
- Trial name
- NCT05002075
- Testing
- m-health cardiac rehabilitation
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Texas Southwestern Medical Center
Thromboembolism, Cardiac Event
Influence of Cardiac Implantable Electronic Devices on the Hemostatic System
The hemostasis system is one of the many biological systems of the human body, designed to preserve the liquid state of blood and prevent its loss during vascular injuries.
- Conditions
- Thromboembolism, Cardiac Event, Hemostatic Disorder
- Trial name
- NCT04499612
- Testing
- Cardiac implantable electronic device implantation., Cardiac implantable electronic device replace., Duplex ultrasound.
- Where
- Russia
- Volunteers
- 250 people
- Sponsor
- Ryazan State Medical University
Heart Failure
The Effectiveness of the Push-Pull-Hold Program on Improving Self-Care in Patients With Heart Failure
This study is a randomized controlled trial that tests the effectiveness of a novel intervention called the Push-Pull-Hold program on improving self-care in patients with heart failure.
- Trial name
- PPHP (NCT03612765)
- Testing
- Push-Pull-Hold Program
- Where
- Singapore
- Volunteers
- 144 people
- Sponsor
- Chinese University of Hong Kong
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