Clinical trials: Congestive Heart Failure, completed
Heart Failure
Use of a Novel SUBCUTaneous Preparation of Furosemide to Facilitate Early Supported Discharge of Patients With Heart Failure
To investigate whether an early supported discharge strategy for patients admitted to hospital because of HF, using a pH neutral subcutaneous (SC) furosemide formulation (SQINFurosemide) at home (delivered by non-CE marked…
- Trial name
- SUBCUT-HF II (NCT05419115)
- Testing
- SQIN-Furosemide, SQIN-Infusor
- Where
- 22 sites in United Kingdom
- Volunteers
- 172 people
- Sponsor
- NHS Greater Glasgow and Clyde
Congenital Heart Defects, Tetralogy Of Fallot
Effects of rhBNP in Pediatrics After Corrective Repair of Tetralogy Of Fallot
The purpose of this study is to determine the effects of rhRNP on urine output and hemodynamics following corrective repair of Tetralogy Of Fallot.
- Trial name
- NCT01941576
- Testing
- recombinant human brain natriuretic peptide (rhBNP)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Heart Failure With Reduced Ejection Fraction, Congestion
ERTU-SODIUM: Study on the Effects of Ertugliflozin on Sodium Storage, Interstitial Volume, and Plasma Volume in HFrEF
The overall hypothesis is that treatment with the SGLT2 inhibitor Ertugliflozin induces a differential regulation in interstitial fluid vs plasma volume, with more reduction of the volume from the interstitial fluid than from the…
- Trial name
- ERTU-SODIUM (NCT05152940)
- Testing
- Ertugliflozin
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Heart Disease, Dyspnea
Screening of Patients Admitted to a Local Hospital With Pocket-sized Ultrasound
Ultrasound (US) is widely used as a diagnostic tool in a hospital setting. In a medical department, diagnosis like heart failure or most kinds of heart diseases, hypervolemia, hypovolemia, pleural effusion, pericardial effusion…
- Conditions
- Heart Disease, Dyspnea, Aortic Disease, Kidney Disease
- Trial name
- NCT01081210
- Testing
- Ultrasound examination
- Where
- 2 sites in Norway
- Volunteers
- 400 people
- Sponsor
- Helse Nord-Trøndelag HF
Cardiac Failure
Validation of a Sensor for Non-invasive Measurement of Stroke Volume and Cardiac Output
toSense, Inc. has developed a novel, non-invasive, body-worn sensor -CoVa Patch-that offers an alternative to invasive continuous cardiac output monitoring.
- Trial name
- NCT04255108
- Testing
- Cova Patch
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baxter Healthcare Corporation
Heart Failure, Cardiac Failure
Impact of the Aerobic Exercise Versus Exercise of Force on the Hemodynamic, Lipidic, Anthropometric and Psychological Variables of Patients With Cardiac Failure
Introduction and objectives: At the global level, cardiovascular diseases are the leading cause of mortality. Currently, rehabilitation programs are shown as an effective treatment to mitigate the effects of heart failure.
- Trial name
- NCT03913780
- Testing
- Aerobic exercise more force
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- University Tolteca
Heart Failure, Congestive
A Family Intervention for Improving Self-Care of Patients With Heart Failure
This is a pilot study of a family-based educational program for patients with heart failure, and their family members.
- Trial name
- NCT00645489
- Testing
- psychoeducational, wait list
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- US Department of Veterans Affairs
Heart Failure, Congestive
An Exploratory Study of Nesiritide in Participants With Acute Heart Failure
The purpose of this exploratory study is to assess the efficacy and safety of nesiritide in participants with acute (a quick and severe form of illness in its early stage) heart failure (when the heart inadequately pumps blood…
- Trial name
- NCT00490724
- Testing
- Nesiritide (1+0.01), Nesiritide (2+0.005), Nesritide (2+0.01)
- Where
- 11 sites in Japan
- Volunteers
- 67 people
- Sponsor
- Janssen Pharmaceutical K.K.
Heart Failure, Metabolic Alkalosis
Metabolic Alkalosis in Heart Failure
Metabolic alkalosis (MA) is the most common acid-base disorder and when it's severe it can have effects on cellular function and contribute to an increase in mortality.
- Conditions
- Heart Failure, Metabolic Alkalosis, Diuretics Drug Reactions, Decompensated Heart Failure
- Trial name
- NCT04740242
- Where
- Spain
- Volunteers
- 672 people
- Sponsor
- Spanish Society of Internal Medicine
Heart Failure
MultiPoint Pacing™ Post Market Study
This is a prospective, multicenter, non-randomized registry/observational study. The study will enroll up to 2,000 patients with successful St.
- Trial name
- MPP-PMS (NCT02832622)
- Testing
- MPP, BiV/MPP
- Where
- 128 sites in United States, Argentina and 2 more
- Volunteers
- 2,169 people
- Sponsor
- Abbott Medical Devices
Heart Failure, Cardiorenal Disease
Safety and Efficacy of ANX-042 in Human Cardiorenal Syndrome
The purpose of this study is to look at kidney function and hormonal function in patients with a history of heart failure and kidney dysfunction, and to see how the use of a new drug, ANX-042, affects those functions.
- Conditions
- Heart Failure, Cardiorenal Disease, Renal Disfunction
- Trial name
- ANX-042 Aim 1 (NCT03019653)
- Testing
- ANX-042
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Acute Decompensated Heart Failure, Volume Overload
Acetazolamide in Decompensated Heart Failure With Volume OveRload (ADVOR)
This clinical research study is being conducted in multiple hospitals in Belgium and approximately 519 patients with acute decompensated heart failure are expected to participate.
- Trial name
- Advor (NCT03505788)
- Testing
- Acetazolamide
- Where
- Belgium
- Volunteers
- 519 people
- Sponsor
- Ziekenhuis Oost-Limburg
Heart Failure
Complex Pathophysiological Background of Heart Failure Deterioration
Preventing heart failure (HF) deterioration is a great challenge for contemporary medicine. The progress course of HF is with increasing frequency of subsequent hospitalizations (approximately 30% of hospitalizations are the…
- Trial name
- NCT02355769
- Where
- Poland
- Volunteers
- 102 people
- Sponsor
- Military Institute od Medicine National Research Institute
Chronic Heart Failure With Low Ejection Fraction
ContriBution of Digital RemOte MoniToring to IMPROVing The Effectiveness of Treatment in Patients With Chronic Heart Failure With Low Ejection Fraction
BOT-IMPROVE-HF is a two-center, parallel group study designed to evaluate the efficacy of up-titration of heart failure treatment using digital remote monitoring after hospitalization due to heart failure decompensation.
- Trial name
- BOT-IMPROVE-HF (NCT06304753)
- Testing
- Telebot
- Where
- 2 sites in Russia
- Volunteers
- 66 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Heart Failure
Cardiac Resynchronization Therapy (CRT) Based Heart Failure Monitoring Study
The purpose of this study is to collect and analyze electrical measurements, timing, and signals from a CRT-D device in heart failure patients who either already have an implanted left atrial pressure sensor or will undergo a…
- Trial name
- zLAP (NCT00632372)
- Testing
- Cardiac Resynchronization Therapy, HeartPOD™ System
- Where
- 10 sites in United States, New Zealand
- Volunteers
- 8 people
- Sponsor
- Abbott Medical Devices
Central Sleep Apneas Syndrome, Heart Failure
PAC-IC-SAS Pilot Study - Central Sleep Apneas Syndrome and Ventricular Function
The aim of this clinical trial is to evaluate the effect of an early treatment of sleep-disordered breathing by adaptive servo-ventilation in heart failure patient following coronary artery bypass graft surgery or other coronary…
- Conditions
- Central Sleep Apneas Syndrome, Heart Failure, Coronary Artery Bypass Graft Surgery or Other Coronary Reperfusion
- Trial name
- NCT01741337
- Testing
- Adaptive servo-ventilation post-operative treatment for 6 months
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Grenoble
Stable Angina, Heart Failure
Plasmonic Nanophotothermal Therapy of Atherosclerosis
The investigators hypothesize that the nanoburning is a very challenging technique to demolish and reverse the plaque especially in combination with stem cell technologies promising the functional restoration of the vessel wall.
- Conditions
- Stable Angina, Heart Failure, Atherosclerosis, Multivessel Coronary Artery Disease
- Trial name
- NANOM-FIM (NCT01270139)
- Testing
- Transplantation of nanoparticles, Transplantation of iron-bearing nanoparticles, Stenting
- Where
- 4 sites in Netherlands, Russia
- Volunteers
- 180 people
- Sponsor
- Ural State Medical University
Heart Failure, Transplant; Failure, Heart
Shear Wave Elastography
In individuals needing a left ventricular assist device (LVAD), right heart failure (RHF) is a serious complication post-surgery, associated with worsened outcomes including mortality.
- Conditions
- Heart Failure, Transplant; Failure, Heart, Decompensated Heart Failure, Fibrosis, Liver
- Trial name
- NCT04493346
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Baylor Research Institute
Heart Failure
Assessment of adherenCe tO Medical theraРy and Its infLuence on Long-term Outcomes In pAtieNts With Heart Failure
The aim of this prospective cohort study is to assess the adherenсe to medical therapy and its influence on long-term outcomes in patients with chronic heart failure in the outpatient registry
- Trial name
- COMPLIANCE (NCT04262583)
- Where
- Russia
- Volunteers
- 72 people
- Sponsor
- National Research Center for Preventive Medicine
Heart Failure, Cancer Treatment Induced Left Ventricular Dysfunction
REcovery of Left Ventricular Dysfunction in CAncer Patients (RECAP Trial)
The goal of this clinical trial is to learn if heart function remains normal after stopping heart failure medication in patients who have received chemotherapy.
- Trial name
- NCT02543294
- Testing
- Echocardiograms, Electrocardiogram, Symptom Questionnaire
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
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