Clinical trials: Congestive Heart Failure, completed
Heart Failure
Food Supplementation Delivered Conditionally vs Not Among Patients With Heart Failure
The current study proposes to investigate if the provision of healthy food can improve outcomes following discharge after HF hospitalization.
- Trial name
- FOOD-HF (NCT06115369)
- Testing
- Medically Tailored Meals Delivered Conditionally, Medically Tailored Meals Delivered Unconditionally, Produce Boxes delivered Conditionally
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Texas Southwestern Medical Center
Congestive Heart Failure
EVEREST: Efficacy of Vasopressin Antagonism in hEart failuRE: Outcome Study With Tolvaptan
The purpose of this study is to compare the effectiveness of tolvaptan or placebo in adults with worsening congestive heart failure (CHF).
- Trial name
- NCT00071331
- Testing
- Tolvaptan
- Where
- 378 sites in United States, Argentina and 16 more
- Volunteers
- 3,600 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Heart Failure, Diastolic Heart Failure
Pharmacokinetics, Pharmacodynamics, and Impact of Inorganic Nitrate on Exercise in HFpEF
This study will be performed to determine the safety, tolerability, and dose-response to inorganic nitrate on exercise capacity in HFpEF. There are two primary goals for this study: 1.
- Trial name
- NCT02256345
- Testing
- KNO3, KCl
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Pennsylvania
Heart Failure
Role of Sacubitril/Valsartan in Improving Provider Performance in Managing Heart Failure Under Medicare Alternative Payment Models
This study evaluated the association between sacubitril/valsartan utilization and HF patients' Part A \& B expenditures within the reimbursement framework of BPCI and MSSP, and identified BPCI/MSSP participants with the greatest…
- Trial name
- NCT05096039
- Testing
- Sacubitril/valsartan, ACEI or ARB and no sacubitril/valsartan
- Where
- United States
- Volunteers
- 1,614,719 people
- Sponsor
- Novartis Pharmaceuticals
Heart Failure
The Heart Failure Readmission Intervention by Variable Early Follow-up (THRIVE) Study
This study is a pragmatic randomized clinical trial to determine the effectiveness of two strategies of early follow-up in adults after hospitalization for heart failure: telephone follow-up with a heart failure care manager vs.
- Trial name
- THRIVE (NCT03524534)
- Testing
- Telephone Call, In-Person Primary Care Clinical Follow-Up Visit
- Volunteers
- 2,091 people
- Sponsor
- Kaiser Permanente
Heart Failure
InSync III Marquis Model 7279 Cardioverter Defibrillator Cardiac Resynchronization System
People who have a dangerously fast heart beat, or whose heart is at risk of stopping beating, may be in need of an electronic device called an implantable cardioverter defibrillator (ICD).
- Trial name
- NCT00271232
- Testing
- Cardiac resynchronization therapy
- Where
- 34 sites in United States
- Volunteers
- 238 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Heart Failure, Cardiac Resynchronization Therapy
Safety and Performance Aspects of CRT-DX System in Patients With Sinus Rhythm
The conventional CRT-D system consists of 3 leads in patients with Heart Failure (HF). A part of HF patients have non-impaired sinus node function and will not be stimulated in the right atrium.
- Trial name
- BIO|REDUCE (NCT03839121)
- Testing
- Cardiac Resynchronization Therapy (CRT)
- Where
- 21 sites in Austria, Czechia and 2 more
- Volunteers
- 113 people
- Sponsor
- Biotronik SE & Co. KG
Heart Failure
Effects of Increased CF-LVAD Pump Speed During Sustained Submaximal Exercise
This randomized trial has been designed to study if it is possible to enhance work capacity during submaximal efforts in heart failure patients supported with continuous-flow left ventricular assist devices (CF-LVAD).
- Trial name
- NCT02335684
- Testing
- CF-LVAD pump speed baseline., CF-LVAD pump speed increased.
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Heart Failure
Assessment of Digital Consultations on Clinical Impact and Efficiency
Healthcare workers have a high workload as compared to other sectors and this burden is projected to increase due to an aging society.
- Trial name
- ADMINISTER (NCT05413447)
- Testing
- Digital consult
- Where
- 5 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Chronic Heart Failure
Efficacy and Safety of Human Neuregulin-1 to Treat Stable Chronic Heart Failure
The mortality of chronic heart failure patients remains high. Recombinant human Neuregulin-1 (rhNRG-1, also called Neucardin) is a 61 amino acid peptide that acts directly on damaged heart muscle cells to restore their structure…
- Trial name
- ZS-01-210 (NCT01251406)
- Testing
- rhNRG-1 Dose 1, rhNRG-1 Dose 2
- Where
- 13 sites in United States
- Volunteers
- 67 people
- Sponsor
- Zensun Sci. & Tech. Co., Ltd.
Heart Failure, Myocardial Infarction
High-intensity Exercise Training in Patients With Post-infarction Heart Failure
Introduction: Moderate-intensity endurance-training is known to reduce symptoms, increase exercise tolerance, and improve quality of life in patients with chronic heart failure.
- Trial name
- NCT00218933
- Testing
- Moderate intensity exercise training, High intensity exercise training
- Where
- Norway
- Volunteers
- 27 people
- Sponsor
- Norwegian University of Science and Technology
Heart Failure
Cardiac Resynchronization Therapy (CRT)-Narrow-dp/Dt-Study
Goal is to examine the efficy of Cardiac Resynchronization Therapy in heart failure patients with narrow QRS complex and optimized medical treatment but echocardiographic desynchronization detection as well as the positve…
- Trial name
- CRT-Narrow (NCT00821938)
- Testing
- LV dp/dt pressure measurement
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Pacemaker
Effects of Inspiratory Muscle and Endurance Training in Heart Failure Patients With Pacemaker
It is well-known that not only peripheral muscles, but also respiratory muscles muscle weakness and deconditioning play an important role in low exercise capacity of patients with Heart Failure (HF).
- Trial name
- NCT03501355
- Testing
- Inspiratory muscle strength training, Inspiratory muscle endurance training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gazi University
Heart Failure, End Stage Renal Disease
Soluble Neprilysin, NT-proBNP, and Growth-Differentiation-Factor-15 as Biomarkers for Heart Failure in Dialysis Patients
Objectives: The aim of this study is to determine whether growth differentiation factor-15 (GDF15) and circulating neprilysin (cNEP) improve the diagnosis of congestive heart failure (HF) in patients on dialysis.
- Trial name
- SONGBIRD (NCT04061811)
- Testing
- Diagnostic biomarker study
- Where
- 2 sites in France, Germany
- Volunteers
- 153 people
- Sponsor
- Hannover Medical School
Heart Failure
Impact of Rosuvastatin on Endothelial Function and Inflammation in Patients With Chronic Heart Failure
Statin therapy has been shown to efficiently reduce mortality in patients with coronary artery disease and myocardial infarction, partially as a result of the lipid-lowering properties of statins.
- Trial name
- NCT00176332
- Testing
- rosuvastatin
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Leipzig
Heart Failure
Mobile Application for Patient Engagement and Physician-Directed Remote Management of Heart Failure
The ENGAGE-HF mobile application tracks three key features over time: (1) heart failure health status, (2) vital signs (e.g., blood pressure, heart rate) and weight, and (3) the quality of heart failure medication therapy.
- Trial name
- ENGAGE-HF (NCT06750549)
- Testing
- ENGAGE-HF Mobile Application
- Where
- 3 sites in United States
- Volunteers
- 134 people
- Sponsor
- University of Michigan
Heart Failure, Congestive
TReatment of Atrial Fibrillation With Dual dEfibrillator in Heart Failure Patients
Demonstrate the efficacy of the device-based managed therapy to treat atrial tachycardia and fibrillation (AT/AF) in patients with CHF indication for implant of a CRT defibrillator and to demonstrate the advantage of automatic…
- Trial name
- TRADE HF (NCT00345592)
- Testing
- Dual (atrial and ventricular) implantable defibrillator
- Where
- 2 sites in Italy
- Volunteers
- 420 people
- Sponsor
- Boston Scientific Corporation
Heart Failure, Diabetes Mellitus
Metabolic Determinants of Cardiac Function
Assessment of cardiac energy metabolism in patients with impaired glucose tolerance
- Trial name
- NCT03386864
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- German Diabetes Center
Chronic Heart Failure, Fear of Physical Activity
Measuring Fear of Physical Activity in Patients With Heart Failure
The study's aims are twofold: First, to examine physiological correlates of fear of physical activity (PA) and second, to examine correlates between fear of PA and interoceptive abilities in patients with chronic heart failure…
- Trial name
- NCT03119298
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Trier
Dementia, Chronic Disease
Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)
The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over…
- Conditions
- Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasm
- Trial name
- PICSI-H (NCT04281784)
- Testing
- EHR-based Clinician Jumpstart
- Where
- 3 sites in United States
- Volunteers
- 2,512 people
- Sponsor
- University of Washington
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.