Clinical trials: Congestive Heart Failure Acute
Heart Failure, Heart Failure Acute
Nitroglycerin vs. Furosemide Using Lung Ultrasound Pilot Trial
Nearly 80% of acute heart failure (AHF) patients admitted to the hospital are initially treated in the emergency department (ED). Once admitted, within 30 days post-discharge, 27% of patients are re-hospitalized or die.
- Conditions
- Heart Failure, Heart Failure Acute, Acute Cardiac Failure, Acute Cardiac Pulmonary Edema
- Trial name
- N-FURIOUS (NCT03259165)
- Testing
- Nitrates, Loop Diuretics
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- Indiana University
Acute Decompensated Heart Failure
REducing 30-day ADMIssions in posT-discharge Subjects (READMIT)
The purpose of this observational study is to collect and characterize multiple physiologic data from a broad subset of subjects with acute heart failure (HF) Changes in physiologic data are expected to correlate with 30-day…
- Trial name
- READMIT-HF (NCT01574144)
- Testing
- AVIVO™ PiiX Patch Monitor System
- Where
- 8 sites in United States, Australia
- Volunteers
- 70 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Congestive Heart Failure
Placebo Controlled, Randomized, Double-blind, Multi-center Study to Investigate the Efficacy and Tolerability of BAY58-2667
The purpose of this study is to assess a dose titration scheme, of a new drug (BAY58-2667) given intravenously, to evaluate if this is safe and can help to improve the well-being, symptoms (e.g.
- Trial name
- NCT00559650
- Testing
- Cinaciguat (BAY58-2667)
- Where
- 72 sites in United States, Canada and 15 more
- Volunteers
- 150 people
- Sponsor
- Bayer
Heart Failure Acute, Renal Dysfunction
Contrast-Induced Acute Kidney Injury Prevention in Acute Heart Failure
The K-PROSE study is a randomized clinical investigation evaluating strategies to prevent contrast-induced acute kidney injury (CI-AKI) in patients hospitalized with acute heart failure and moderate renal dysfunction (eGFR 30-75…
- Trial name
- K-PROSE (NCT07550790)
- Testing
- Furosemide, 0.9 % Normal Saline
- Where
- South Korea
- Volunteers
- 190 people
- Sponsor
- Jin Joo Park
Cardiovascular Disease Acute, Emergency Department Patient
Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers
The aim of this study is to assess emergency medicine physician and advanced practice provider (APP) knowledge and technical skill in performance of a point-of-care ultrasound simulation and just-in-time training pathway to…
- Conditions
- Cardiovascular Disease Acute, Emergency Department Patient, Heart Failure Acute, Pulmonary Embolism (Diagnosis)
- Trial name
- NCT07159269
- Testing
- Cardiac point-of-care ultrasound (POCUS) training and clinical pathway
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Duke University
Acute Heart Failure, Pulmonary Congestion
LUS in Acute Heart Failure Therapeutic Adaptation
Evaluate lung ultrasound aspect according to diuretics dosage evolution in patients hospitalized for acute heart failure.
- Trial name
- EPPICA (NCT04633629)
- Testing
- Lung ultrasound
- Volunteers
- 94 people
- Sponsor
- University Hospital, Grenoble
Heart Failure, Systolic, Heart Failure; With Decompensation
Fluid Restriction in Patients With Heart Failure
There is a concept increasingly consolidated by clinical evidence that at each hospitalization due to HF decompensation there is a substantial loss of quality of life, which is associated with an initial period of great clinical…
- Conditions
- Heart Failure, Systolic, Heart Failure; With Decompensation, Pulmonary Congestion
- Trial name
- NCT04611594
- Testing
- Fluid restriction
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Myocardial Infarction, Heart Failure
Levosimendan in Acute Heart Failure Following Acute Myocardial Infarction.
The purpose of this study is to determine the safety and efficacy of a 24 hour infusion with levosimendan in patients with acute myocardial infarction and heart failure after acute percutaneous coronary intervention (PCI)…
- Conditions
- Myocardial Infarction, Heart Failure, Cardiogenic Shock
- Trial name
- NCT00324766
- Testing
- levosimendan
- Where
- Norway
- Volunteers
- 61 people
- Sponsor
- Oslo University Hospital
Heart Failure With Reduced Ejection Fraction
Ketones in Heart Failure With Reduced Ejection Fraction
The purpose of this study is to understand the effects of a ketone drink on exercise capacity and other cardiovascular parameters in patients with heart failure.
- Trial name
- HFrEF (NCT06195982)
- Testing
- ketone ester
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
Aged
Frailty in Elderly Patients Receiving Cardiac Interventional Procedures
In Italy, life expectancy at birth has reached 80 years in men and 85 in women; in about 50 years, life expectancy at the age of 80 has increased by an extraordinary 61% and 55%, respectively, due to more effective therapies and…
- Trial name
- FRASER (NCT02386124)
- Testing
- frailty evaluation
- Where
- Italy
- Volunteers
- 402 people
- Sponsor
- University Hospital of Ferrara
Acute Heart Failure (AHF)
Impact of Clinical Ultrasound in Patients With Heart Failure Treated in Home Hospitalization
The purpose of this study is to assess whether clinical ultrasound (CU)-guided treatment in acute heart failure (AHF) is superior to the standard care (SC)-guided treatment.
- Trial name
- AHF-CU (NCT05042752)
- Testing
- CLINICAL ULTRASOUND
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Lara Palacios
Heart Decompensation
Skeletal Muscles in Acute Heart Failure
The study will include 30 consecutive patients with acute heart failure (AHF). In 20 patients the investigators will perform cardiologic rehabilitation.
- Trial name
- NCT03102164
- Testing
- cardiac rehabilitation
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Heart Failure
Dapa Acute Heart Failure Study
Heart failure (HF) is one of the most important reasons for hospital admission and is associated with high mortality and morbidity.
- Trial name
- NCT05759000
- Testing
- Dapagliflozin
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
Sleep Disorders, Sleep Apnea
Bedside Sleep Medicine
The investigators aimed to evaluated the role of bedside sleep medicine in an cardiology intensive care unit. The patients will be submitted to a overnight polysomnography.
- Conditions
- Sleep Disorders, Sleep Apnea, Acute Myocardial Infarction, Acute Decompensated Heart Failure
- Trial name
- NCT01924507
- Testing
- CPAP
- Where
- Brazil
- Volunteers
- 400 people
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Acute Heart Failure
Early Treatment With a Sodium-glucose Co-transporter 2 Inhibitor in High-risk Patients With Acute Heart Failure
The EMPA-AHF trial is a multicentre, randomized, double-blind, placebo-controlled trial designed to evaluate the efficacy and safety of early initiation of once-daily oral empagliflozin 10 mg in patients hospitalized for patients…
- Trial name
- EMPA-AHF (NCT05392764)
- Testing
- Empagliflozin 10 MG
- Where
- 69 sites in Japan
- Volunteers
- 444 people
- Sponsor
- Juntendo University
Heart Failure
OUTpatient Intravenous LASix Trial in Reducing Hospitalization for Acute Decompensated Heart Failure
Single-center, prospective double-blinded randomized control trial to evaluate the the feasibility, efficacy and safety of outpatient IV diuretic therapy in treatment of heart failure.
- Trial name
- OUTLAST (NCT04691687)
- Testing
- Furosemide, IV Solution
- Volunteers
- 100 people
- Sponsor
- New York Presbyterian Brooklyn Methodist Hospital
Acute Decompensated Heart Failure
Study of the Safety of BMS-986259 in Participants With Post-Acute Decompensated Heart Failure
The purpose of the study is to assess the safety of BMS-986259 in stable participants hospitalized for acute decompensated heart failure.
- Trial name
- NCT04318093
- Testing
- BMS-986259
- Where
- 18 sites in Argentina, Czechia and 4 more
- Volunteers
- 25 people
- Sponsor
- Bristol-Myers Squibb
Acute Coronary Syndrome, Heart Failure
Effect of Air Pollution in the Haifa Bay Area on Cardiovascular Morbidity and Mortality
The association between exposure to ambient air pollution and pulmonary disease has been well established.To date no study has assessed the burden of cardiovascular disease in Israel and its relation to ambient air pollution.
- Conditions
- Acute Coronary Syndrome, Heart Failure, Arrhythmia
- Trial name
- NCT01325155
- Volunteers
- 5,000 people
- Sponsor
- Rambam Health Care Campus
Pulmonary Arterial Hypertension, Heart Failure
Effects of Apelin on the Lung Circulation in Pulmonary Hypertension
The purpose of this study is to determine the effects of Apelin on the lung circulation. The investigators hypothesise that Apelin will relax the lung blood vessels and improve the pumping ability of the heart.
- Trial name
- NCT01457170
- Testing
- Apelin
- Where
- 3 sites in United Kingdom
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Golden Jubilee National Hospital
Dyspnea; Cardiac
Contribution LUS in the Diagnosis of Acute Heart Failure (AHF) in Patients Admitted to the ED
This study assesses the potential of lung ultrasonography to diagnose heart failure.
- Trial name
- NCT03717779
- Testing
- lung ultrasound
- Where
- Tunisia
- Volunteers
- 600 people
- Sponsor
- University of Monastir