Clinical trials: Congestive Heart Failure Acute
Acute Decompensated Heart Failure, Acute Heart Failure
SVC Occlusion in Subjects With Acute Decompensated Heart Failure
Safety and performance evaluation of the preCARDIA System for patients with ADHF.
- Conditions
- Acute Decompensated Heart Failure, Acute Heart Failure, Congestive Heart Failure, Heart Diseases
- Trial name
- VENUS-HF (NCT03836079)
- Testing
- preCARDIA system
- Where
- 17 sites in United States
- Volunteers
- 60 people
- Sponsor
- Abiomed Inc.
CHF
FAST PV and mGFR™ Technology in Congestive Heart Failure
This is an investigator-initiated, one-armed, phase 2 clinical trial using an injectable fluorescent tracer to assay and evaluate measured plasma volume (mPV) and measured glomerular filtration rate (mGFR) in hospitalized…
- Trial name
- NCT03808948
- Testing
- VFI
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Heart Failure，Congestive
Artificial Intelligence and Smart Wearable Technologies for Early Detection of Acute Heart Failure
Heart failure is the major pandemic of the 21st century. The number of patients and of Heart Failure-related deaths is progressively increasing. This means a devastating economic and health organization burden.
- Trial name
- weHeartClinic (NCT05591443)
- Volunteers
- 120 people
- Sponsor
- Centro Cardiologico Monzino
Coronary Artery Aneurysm
Coronary Artery Aneurysm Registry
International registry gathering patients with angiographically confirmed coronary aneurysm.
- Trial name
- CAAR (NCT02563626)
- Where
- Spain
- Volunteers
- 1,565 people
- Sponsor
- St Carlos Hospital, Madrid, Spain
Acute Heart Failure With Reduced Ejection Fraction
A Study to Assess the Hemodynamic Effects, Safety, Tolerability, and Pharmacokinetics of Intravenous APD418 in Adult Participants With Heart Failure With Reduced Ejection Fraction
The purpose of this study is to evaluate the safety, pharmacokinetics, and effect on cardiac function of intravenous APD418 in adult participants with heart failure with reduced ejection fraction (HFrEF).
- Trial name
- NCT05139615
- Testing
- APD418
- Where
- 21 sites in United States, Germany and 3 more
- Volunteers
- 22 people
- Sponsor
- Pfizer
Acute Respiratory Distress Syndrome, Septic Shock
Organ-substituting Technologies in the Treatment of Heart and Pulmonary Failure
The implementation of this project will improve the effectiveness of surgical treatment and reduce the level of complications and mortality among patients with heart failure and heart failure in the terminal stage.
- Conditions
- Acute Respiratory Distress Syndrome, Septic Shock, Sepsis
- Trial name
- OST (NCT05042622)
- Testing
- Cytokine adsorber filter, Extracorporeal hemoperfusion cartridge
- Where
- Kazakhstan
- Volunteers
- 90 people
- Sponsor
- National Research Center for Cardiac Surgery, Kazakhstan
Cardiogenic Shock
Efficacy and Safety on Heart Rate Control With Ivabradine on Cardiogenic Shock
This is a randomized 1:1 blinded study that evaluate in acute left heart failure-cardiogenic shock patients if ivabradine treatment can reduce pulmonary wedge pressure, without inducing a significant or relevant reduction in…
- Trial name
- ES-FISH (NCT03437369)
- Testing
- Ivabradine Oral Tablet, Standard of Care treatment
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Acute Heart Failure, COPD Exacerbation
Use of PARniv for Early Diagnosis of LVF in AECOPD
Left ventricular failure (LVF) is a common cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This association is frequently underestimated with regard to the difficulty of clinical diagnosis .
- Trial name
- NCT05189119
- Testing
- non invasive ventilation
- Where
- Tunisia
- Volunteers
- 80 people
- Sponsor
- University of Monastir
Acute Heart Failure
Dynamic Variation of Impedance Cardiography(DYVIC) as a Diagnostic Tool of Acute Heart Failure (AHF)
Dynamic variations of bio-impedance measured cardiac output using non pharmacologic intervention (sitting position, passive leg rising and valsalva maneuver) could be used to detect acute heart failure in patients admitted to the…
- Trial name
- DYVIC (NCT03241069)
- Testing
- Reference position, sitting position, Valsalva maneuver
- Where
- Tunisia
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Congestive Heart Failure
Metabolic Derangements in Acute Heart Failure Syndrome
To determine the association of both neurohormonal and hemodynamic alterations associated with metabolic abnormalities in acute heart failure syndrome.
- Trial name
- NCT00682175
- Testing
- Observational
- Volunteers
- 100 people
- Sponsor
- The Cleveland Clinic
Dyspnea, Heart Failure Acute
Evaluation of the Effectiveness of the CardioStory Device in Distinguishing Heart Failure From Other Causes in Patients Presenting With Dyspnea
The CARDIOSTORY.TN study is a prospective observational study at Sahloul University Hospital (Sousse, Tunisia) evaluating the CardioStory device for distinguishing heart failure (HF) from other causes of acute dyspnea.
- Trial name
- CARDIOSTORY (NCT07147699)
- Testing
- cardiostory
- Sponsor
- Hôpital Universitaire Sahloul
Heart Failure, Acute Heart Failure
Randomized Controlled Trial of urinE chemiStry Guided aCute heArt faiLure treATmEnt (ESCALATE)
This is a randomized trial of protocolized diuretic therapy guided by urinary sodium compared to structured usual care in ED patients with AHF.
- Trial name
- ESCALATE (NCT04481919)
- Testing
- Protocolized diuretic therapy
- Where
- 2 sites in United States
- Volunteers
- 474 people
- Sponsor
- Vanderbilt University Medical Center
ADHF
Troponin I Release After High Diuretic Doses
High values of cardiac troponin (Ct) in acute heart failure (ADHF) identify patients (pts) at higher risk and worsened prognosis.
- Trial name
- Tra-HSS-Fur (NCT01419132)
- Testing
- Furosemide
- Where
- 3 sites in Italy
- Volunteers
- 60 people
- Sponsor
- University of Palermo
Myocardial Infarction (MI), Pacemaker Implantation
Augmented Reality as Discharge Information for Hospitalized Cardiology Patients
The goal of this clinical trial is to find out whether a simple augmented reality tool provided at hospital discharge can improve patients' understanding of their care, adherence to treatment, and health outcomes, compared with…
- Conditions
- Myocardial Infarction (MI), Pacemaker Implantation, Heart Failure, Atrial Fibrillation (AF)
- Trial name
- RACAR (NCT07399379)
- Testing
- Augmented reality app
- Where
- Spain
- Volunteers
- 303 people
- Sponsor
- Hospital Universitario Getafe
Cardiovascular Diseases, Heart Diseases
Cardiovascular Magnetic Resonance for the Occluded Infarct-Related Artery Treatment
The purpose of this study is to determine whether opening an occluded infarcted artery 3-28 days after an acute myocardial infarction in high-risk asymptomatic patients with preserved infarct zone viability improves left…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Infarction, Heart Failure
- Trial name
- COAT (NCT00968383)
- Testing
- Beta adrenergic blockers, Platelet inhibitors, Statins
- Where
- Poland
- Volunteers
- 11 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Acute Heart Failure
Metabolic Modulation as Treatment in Acute Heart Failure
The primary objective of this study is to evaluate whether metabolic modulation improves hemodynamics and outcome in acute heart failure
- Trial name
- MEMO (NCT00449423)
- Testing
- acipimox
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- University of Aarhus
Advanced Heart Failure, Heart Transplantation
Non-invasive Evaluation of Heart Transplant Rejection- Pilot Study
The purpose of this research study is to apply new non-invasive, no-risk techniques to a cardiac transplant population for assessment of their reliability in detecting heart transplant rejection.
- Trial name
- NCT00572286
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Heart Failure
Strain Echo in Acute Heart Failure
The purpose of this project is to evaluate the utility of left ventricular strain as part of the assessment of patients in the emergency department with acute heart failure (HF).
- Trial name
- Strain Echo (NCT02371642)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Wayne State University
Heart Failure, Congestive
ZP120 Add-on to Furosemide in Treatment of Acute or Sub-Acute Decompensated Heart Failure
The main purpose of this study is to see if the experimental drug ZP120, when given with the approved drug furosemide to patients with acute or sub-acute heart failure, can reduce the amount of fluid in the patients' lungs and…
- Trial name
- NCT00283361
- Testing
- ZP120, I.v. catherization, 6-minutes walk performance
- Where
- 22 sites in United States
- Volunteers
- 130 people
- Sponsor
- Zealand Pharma
Acute Heart Failure, Volume Overload
Infusion of Furosemide to Improve Diuretic Efficiency in Acute Heart Failure
Acute heart failure is a condition where the heart suddenly cannot pump blood well enough for the body's needs. Many people admitted to the hospital with acute heart failure have too much fluid in the body.
- Trial name
- INFUSE-AHF (NCT07577596)
- Testing
- Intravenous furosemide continuous infusion, Intravenous furosemide bolus injections
- Where
- Denmark
- Volunteers
- 436 people
- Sponsor
- University of Aarhus