Clinical trials: Congestive Heart Failure Acute
Heart Failure
Early Care After Discharge of HF Patients
After decompensated heart failure, a number of patients have high risk of early rehospitalization as well as death. Specialized medical management for a short period but very early after discharge could be critical for optimizing…
- Trial name
- ECAD-HF (NCT01820780)
- Testing
- Natriuretic peptides levels to J7 and J14, Consultations specialized to J7 and J14, Phone calls in 6 months and 12 months
- Where
- France
- Volunteers
- 507 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heart Failure
Use of mHealth to Increase Physical Activity for Patients Recently Hospitalized With Acute Heart Failure
The aim of this trial is to determine if a mobile application that promotes physical exercise in the follow-up of patients recently hospitalized with acute heart failure can improve exercise capacity after 6 months and physical…
- Trial name
- mRehab (NCT04848298)
- Testing
- mHealth Intervention
- Where
- Spain
- Volunteers
- 116 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Heart Failure; With Decompensation
Targeting LOXL2 and Cardiac Fibrosis for Post-acute Heart Failure Treatment- A Prospective Study
A previous study demonstrated that a multidisciplinary cardiac rehabilitation (CR) program was associated with reduced medium- to long-term all-cause mortality in a retrospective propensity score-matched study.
- Trial name
- NCT05498584
- Testing
- exercise based cardiac rehabilitation
- Where
- Taiwan
- Volunteers
- 130 people
- Sponsor
- Chang Gung Memorial Hospital
Acute Decompensated Heart Failure
EACH-ADHF: Early Comprehensive Rehabilitation in Patients With ADHF
EACH-ADHF: Early Comprehensive Rehabilitation in patients with ADHF study is a multi-center, parallel-group, randomized controlled trial designed to evaluate the effects of the early comprehensive rehabilitation including…
- Trial name
- EACH-ADHF (NCT06161987)
- Testing
- Early comprehensive rehabilitation
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Guangdong Provincial People's Hospital
Acute Myocardial Infarction, Heart Failure
Stress Management Modified Cardiac Rehabilitation in Patients After Acute Myocardial Infarction or Heart Failure
The purposes of this study is to evaluate the improvement of a stress management involved cardiac rehabilitation program on the psychological states, quality of life and clinical outcomes of patients after acute myocardial…
- Trial name
- NCT03905187
- Testing
- Modified CR, Traditional CR, Education
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Jing Ma
Pneumonia, Syncope
Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)
The Next Day Clinic (NDC) is a quality improvement initiative that will be launched and operated by UCLA Health starting July 22, 2024. Its goals are to improve patient care and safety and to maximize cost effectiveness.
- Conditions
- Pneumonia, Syncope, Congestive Heart Failure, Cellulitis
- Trial name
- NDC (NCT06526884)
- Testing
- Next Day Clinic
- Where
- United States
- Volunteers
- 570 people
- Sponsor
- University of California, Los Angeles
Heart Failure, Systolic Heart Failure
Manipal Heart Failure Registry (MHFR)
Burden of HF in India is approximate 2-5 million patients with an estimated prevalence of 2-3/1000 population. HF is responsible for approx1.8 million admissions annually in India.
- Conditions
- Heart Failure, Systolic Heart Failure, Diastolic Heart Failure, Decompensated Heart Failure
- Trial name
- MHFR (NCT03157219)
- Where
- India
- Volunteers
- 500 people
- Sponsor
- Manipal University
Cardiovascular Diseases, Coronary Artery Disease
Optimising Secondary Prevention and Quality of Life in Early Cardiac Rehabilitation
The primary aim of this research is to explore the adherence and drop-out from early cardiac rehabilitation (CR), to inform interventions to support patient's adherence to CR and facilitate maintenance.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Myocardial Infarction, Acute Coronary Syndrome
- Trial name
- OSPREY-CR (NCT04781699)
- Where
- 6 sites in United Kingdom
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Heart Failure
High Sensitivity cTnT Rules Out Cardiac Insufficiency Trial (TACIT)
The purpose of this study is to better understand myocardial injury in AHF. Secondary analyses demonstrate the prognostic significance of troponin release. The absence of such release has been associated with less risk.
- Trial name
- TACIT (NCT02592135)
- Testing
- hsTnT level
- Where
- 5 sites in United States
- Volunteers
- 500 people
- Sponsor
- Indiana University
Acute Heart Failure (AHF), Congestive Heart Failure(CHF)
Evaluating Residual Congestion at Discharge in Acute Heart Failure Patients
Treatment of congestion is one of the main goals in patients hospitalized for acute heart failure. Nevertheless, current evidence shows that decongestion is often not achieved and that residual congestion at discharge is strongly…
- Trial name
- NCT06993220
- Testing
- Evaluation of residual congestion at discharge
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Consorci Sanitari Integral
Heart Failure Acute, Heart Failure
Cardiac Output Autonomic Stimulation Therapy for Heart Failure - Hemodynamic Effects
A single-arm study to observe NeuroTronik Cardiac Autonomic Nerve Stimulation (CANS) Therapy System hemodynamic and other physiologic effects.
- Trial name
- COAST-HF FX (NCT03542123)
- Testing
- NeuroTronik CANS Therapy® System
- Where
- Paraguay
- Volunteers
- 30 people
- Sponsor
- NeuroTronik Inc.
Cardiogenic Shock, Acute Myocardial Infarction
Clinical Evaluation of NIRSense Tissue Oximetry Sensor Monitoring to Early Detect Cardiogenic Shock
This is a prospective, single-center, observational pilot study of the investigational NIRSense Tissue Oximetry Sensor System (Envello Core), a noninvasive wearable sensor patch that uses near-infrared spectroscopy (NIRS) and…
- Conditions
- Cardiogenic Shock, Acute Myocardial Infarction, Acute Decompensated Heart Failure
- Trial name
- NCT07825363
- Testing
- NIRSense Tissue Oximetry Sensor System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NIRSense Inc.
Acute Heart Failure, Diabetes Mellitus
Short Term Outcome of Acute Heart Failure in Diabetic and Non Diabetic Patients
Around 26 million people suffer from heart failure (HF) globally, and the prevalence is increasing with an increasing longevity, prevalence of risk factors, and improved survival in patients with cardiovascular diseases In Egypt…
- Trial name
- NCT06447467
- Testing
- pro BNP
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Heart Failure
Monitor Patients With Acute Heart Failure
This is a prospective, multi-center, non-randomized study to evaluate performance of an external monitor for heart failure patients
- Trial name
- ACUTE (NCT00919828)
- Testing
- Avivo System
- Volunteers
- 60 people
- Sponsor
- Corventis, Inc.
Takotsubo Cardiomyopathy
Cyclosporine In Takotsubo Syndrome
The goal of this clinical trial is to investigate the impact of repetitive acute Cyclosporine A (CsA) bolus therapy in patients suffering from TTS with an elevated risk of impaired outcome.
- Trial name
- CIT (NCT05946772)
- Testing
- Cyclosporine A
- Where
- 24 sites in Germany
- Volunteers
- 204 people
- Sponsor
- University Hospital Heidelberg
Kidney Failure, Chronic, Kidney Failure, Acute
Sodium Chloride and Contrast Nephropathy
This phase II, open, non-inferiority, randomized and controlled clinical trial is aimed to ascertain the incidence of contrast nephropathy in outpatients undergoing CT scan with contrast.
- Conditions
- Kidney Failure, Chronic, Kidney Failure, Acute, Heart Failure, Diabetes
- Trial name
- PNIC-Na (NCT03476460)
- Testing
- Oral sodium chloride, Intravenous sodium chloride
- Where
- Spain
- Volunteers
- 271 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Heart Failure, Dyspnea
NT-proBNP in Acute Dyspnea: Effects on Treatment, Hospitalisation and Costs
Diagnostic uncertainty in patients with complaints of shortness of breath presenting to the Emergency Department of a hospital may delay treatment and proper care.
- Trial name
- NCT00410293
- Testing
- NT-proBNP testing
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Erasmus Medical Center
Myocardial Infarction
Safety Study of Adult Mesenchymal Stem Cells (MSC) to Treat Acute Myocardial Infarction
The purpose of the study is to determine whether adult stem cells [Provacel™(PUMP1)] are safe and possibly effective in the treatment of acute myocardial infarction (heart attack).
- Trial name
- NCT00114452
- Testing
- Provacel
- Where
- 15 sites in United States
- Volunteers
- 60 people
- Sponsor
- Mesoblast, Inc.
Cardiovascular Diseases
Tissue Doppler Assessment of Right Ventricular Performance in Acute Heeart Failure
The primary purpose of this study is to learn if taking pictures of your heart using two dimensional and three dimensional echocardiography in the heart failure intensive care unit can be helpful to understanding how the heart is…
- Trial name
- TARVA (NCT00589758)
- Testing
- Echocardiography, Biomarker evaluation
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- The Cleveland Clinic
Acute Coronary Syndromes, Heart Failure
Prospective Cohort of Acute Cardiology Referrals in an Ambulatory Day-Hospital Setting
Suspected acute or subacute cardiovascular diseases-including chest pain, dyspnea, and palpitations-are among the most common reasons for unscheduled emergency department visits and pre-hospital referrals.
- Conditions
- Acute Coronary Syndromes, Heart Failure, Pulmonary Embolism, Deep Vein Thrombosis, HTN-Hypertension
- Trial name
- CESAR (NCT07675434)
- Volunteers
- 25,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris