Clinical trials: Connective Tissue Disorders
Breast Cancer, Neurocognitive Impairment
Examining a Common Complaint of Women Who Receive Chemotherapy for Breast Cancer- Cognitive Difficulty
This longitudinal project will investigate a common complaint of women who receive chemotherapy for breast cancer- cognitive difficulty.
- Conditions
- Breast Cancer, Neurocognitive Impairment, Quality of Life
- Trial name
- NCT01553097
- Testing
- Neurocognitive impairment observation
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Ehler's Danlos Syndrome, Obstructive Sleep Apnea
Obstructive Sleep Apnoea in Children and Adolescents With Ehlers-Danlos Syndrome
Ehlers-Danlos Syndrome (EDS) is a clinically and genetically heterogeneous group of inherited connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility.
- Trial name
- NCT02712060
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Individual Adjustment, Itch; Athlete
Electromyographic Analysis And Body Balance In The Use Of Athletes After Cryotherapy By Immersion Ankle
The influence of cryotherapy on ankle motor control and balance of athletes is controversial. The aim of this study is to assess the neuromuscular response of the dominant leg and body balance basketball athletes after…
- Trial name
- NCT01870414
- Testing
- cryotherapy by immersion
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Rheumatoid Arthritis
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial
Rheumatoid Arthritis (RA) is a chronic inflammatory disease characterized by joint swelling, joint tenderness and destruction of synovial joints, leading to severe disability and premature mortality.
- Trial name
- NCT03194204
- Testing
- Doxycycline Tablets
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assiut University
Lipedema
Manual and Self-Lymphatic Drainage Combined With Exercise in Women With Lipedema
This randomized controlled study aims to compare the effects of two physiotherapy approaches in women with lipedema. Participants will be assigned to either manual lymphatic drainage combined with supervised aerobic exercise or…
- Trial name
- LipoMOVE (NCT07803926)
- Testing
- Manual Lymphatic Drainage, Aerobic Exercise, Self-Lymphatic Drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Merve SEVINC GUNDUZ
Lactation Induced
Effect of OMEGA 3 Fatty Acids on Lactation Period
The World Health Organization (WHO) and the United Nations Children's Fund (UNICEF) recommend that babies be exclusively breastfed for the first 6 months from birth.
- Trial name
- NCT06111378
- Testing
- fish oil, linseed oil, walnut oil
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Penile/Perineal /Perianal Intraepithelial Neoplasia, Anal Intraepithelial Neoplasia
A Phase III Trial to Evaluate the Efficacy, Immunogenicity and Safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) in Chinese Males
This phase III clinical trial was designed to evaluate the efficacy, immunogenicity and safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) manufactured by Xiamen…
- Conditions
- Penile/Perineal /Perianal Intraepithelial Neoplasia, Anal Intraepithelial Neoplasia, Penile/Perianal/Perineal Cancer, Anal Cancer
- Trial name
- NCT06866574
- Testing
- Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.coli), Aluminum Adjuvant
- Where
- 4 sites in China
- Volunteers
- 9,300 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Foot Diseases
Comparison of the Effects of Virtual Reality-Based Interventions on Foot Function, Foot Pressure, and Balance in Sedentary Individuals
Comparison of the Effects of Virtual Reality-Based Interventions on Foot Function, Foot Pressure, and Balance in Sedentary Individuals
- Trial name
- NCT07260747
- Testing
- VR Biodex Group, Video-Based VR Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Diabetic Foot, Leg Ulcer
Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study
The objective of this study protocol is to use wound biopsies that have been obtained during standard of care management for further scientific evaluation after standard evaluation by a pathologist.
- Conditions
- Diabetic Foot, Leg Ulcer, Decubitus Ulcer
- Trial name
- NCT00759889
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southwest Regional Wound Care Center
Cutaneous Melanoma, Stage II, Malignant Cutaneous Melanoma
Evaluation of Oncoxin-Viusid® in Cutaneous Melanoma
Malignant melanoma, responsible for 75% of deaths from skin cancer. Current therapeutic options have poor response, many adverse events and high costs.
- Conditions
- Cutaneous Melanoma, Stage II, Malignant Cutaneous Melanoma, Cutaneous Melanoma, Stage III
- Trial name
- NCT03541148
- Testing
- Oncoxin-Viusid
- Where
- Cuba
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Catalysis SL
Cellulite
Treatment for Cellulite Appearance
Open-label, non-randomized, prospective, multi-center, self-controlled clinical study with masked evaluation.
- Trial name
- NCT05358847
- Testing
- Sofwave
- Where
- 4 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Pharmacokinetics, Safety Issues
A Clinical Study With Adalimumab Biosimilar
The study aims to evaluate the pharmacokinetic profile, safety profile, and immunogenic potential of adalimumab of a new citrate-free formulation of adalimumab (Adalimumab Richmond) [Test Product] vs.
- Trial name
- NCT06291948
- Testing
- Humira® (adalimumab) AC Pen [Reference Product], Adalimumab Richmond [Test Product]
- Where
- Argentina
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Laboratorios Richmond S.A.C.I.F.
Photosensitivity, Microvesicle Particle
Testing Use of Topical Imipramine in Reducing Ultraviolet B Induced Microvesicle Particle Release in Photosensitive Subjects
The purpose of this study is three-fold. First, researchers will assess whether subjects who have clinically abnormal reactions to sunlight (photosensitivity) have increased levels of microvesicle particles (MVP) following…
- Trial name
- NCT04520217
- Testing
- 4% Imipramine Cream, Base Cream
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wright State University
Dermatomyositis, Myocardial Repolarization
Evaluation of Tp-e Interval and Tp-e/QT Ratio in Dermatomyositis and Analysis of Their Relationship With Inflammation
The goal of this observational study is to investigate ventricular repolarization utilizing Tp-e intervals and Tp-e/QT ratios in patients with DM.
- Conditions
- Dermatomyositis, Myocardial Repolarization, Inflammation
- Trial name
- NCT06002750
- Testing
- disease
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Third People's Hospital of Hangzhou
Healthy, Premenopausal Period
Effects of Omega-3 Fatty Acids on Risk Factors for Breast Cancer in Pre-menopausal Women
Healthy premenopausal women were enrolled in a diet intervention study that examined the effect of a combination EPA/DHA supplement on risk factors associated with breast cancer.
- Trial name
- NCT02816125
- Testing
- omega-3 fatty acid
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Rosacea, Papulopustular
Azelaic Acid Foam 15% in the Treatment of Papulopustular Rosacea
This research study is being performed to evaluate the photographic evidence of the efficacy and tolerability of Azelaic Acid Foam 15% in the treatment of papulopustular rosacea.
- Trial name
- NCT03418610
- Testing
- Azelaic Acid foam 15%
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Clinical Research Center of the Carolinas
SARS-Cov-2 Infection, Rheumatoid Arthritis
Deciphering a Specific Signature of the Immunosenescence Induced in COVID-19+ Patients Versus Rheumatoid Arthritis Patients
Immune aging or immunosenescence is characterized by a loss of T cell clonal diversity and a contraction of naïve T cells with proliferative capacity associated with the functional impairment of many others immune cells as well…
- Trial name
- SENO-COVID (NCT04880720)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Breast Cancer
The Efficacy and Safety of Abraxane Combined With Epirubicin as Neoadjuvant Chemotherapy in Breast Cancer
Some studies have demonstrated the efficacy of Abraxane in treating breast cancer in both adjuvant and metastatic settings. Few data is available on Abraxane in neoadjuvant treatment for breast cancer.
- Trial name
- NCT03647280
- Testing
- Abraxane, Epirubicin
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zhejiang Cancer Hospital
Breast Cancer
Validity of Sentinel Lymphnode Biopsy After Neoadjuvant Chemotherapy Cancer Patients With Radiologically Positive Axillary Lymph Nodes
Sentinel lymph node biopsy (SLNB) after neoadjuvant chemotherapy (NAC) is currently debatable. It is possible that the tumor response to chemotherapy may alter the lymphatic drainage thus causing lower SLN identification rate and…
- Trial name
- VSNBNAC (NCT01622478)
- Testing
- Sentinel lymph node biopsy, Neoadjuvant chemotherapy, complete axillary lymph node dissection
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Baldness
Impact of Low-Level Laser Therapy on Hair Regrowth Post PRP Treatment
Low-level laser stimulates cells in the hair follicles, which promotes hair growth. The patient's own blood platelets are used in platelet-rich plasma treatment to encourage hair growth.
- Trial name
- NCT07048626
- Testing
- PRP treatment, low level laser therapy post prp treatment
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Superior University