Clinical trials: Conns Syndrome
Hyperaldosteronism, Renal Insufficiency
The Water Intake Trail and Primary Aldosteronism Postoperation(WIT-PAP)
To investigate whether increasing water intake has renal protective effect on PA patients after surgical treatment.
- Trial name
- NCT04150666
- Testing
- Hydration
- Where
- China
- Sponsor
- Qifu Li
Primary Aldosteronism, Primary Hyperaldosteronism
Primary Aldosteronism in General Practice: Organ Damage, Epidemiology and Treatment
Primary aldosteronism (PA) is the most frequent form of secondary hypertension. It is caused by autonomous secretion of aldosterone, encompassing a group of disorders which is for 99% predominated by unilateral…
- Trial name
- PAGODE (NCT01728493)
- Where
- Netherlands
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Primary Aldosteronism
Metabolic Syndrome and Insulin Resistance in Primary Aldosteronism
Primary aldosteronism (PA) is occasionally associated with impaired glucose tolerance. Glucose intolerance, in general metabolic syndrome is caused by suppression of insulin release from the pancreas and suppression of insulin…
- Trial name
- NCT00173082
- Testing
- Glucose tolerance test
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Primary Aldosteronism
Open-label Study on Treatment of Primary Aldosteronism With Everolimus
The overall objective is to evaluate everolimus as an aldosterone-lowering drug in the treatment of primary hyperaldosteronism.
- Trial name
- NCT03174171
- Testing
- Everolimus 0.75 mg
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- University Hospital, Basel, Switzerland
Primary Aldosteronism, Hypertension
Adrenal Artery Ablation Treats Primary Aldosteronism
Primary aldosteronism (PA) is one of the most common cause of endocrine and resistant hypertension. Current studies have shown that the activation of the renin-angiotensin-aldosterone system (RAAS) and the increased sympathetic…
- Trial name
- NCT03398785
- Testing
- Endovascular chemical Ablation of Adrenal Gland
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Third Military Medical University
Hyperaldosteronism, Hypertension
Diagnostic Properties of Aldosterone-Renin Ratio in Primary Aldosteronism Among Hypertensives.
This study aims to evaluate the diagnostic value of the Aldosterone-Renin Ratio (ARR)as a screening test for primary aldosteronism among hypertensives. The test characteristics will be studied.
- Trial name
- NCT00407784
- Testing
- eplerenone
- Where
- 13 sites in Netherlands
- Volunteers
- 500 people
- Sponsor
- Erasmus Medical Center
Primary Aldosteronism
Comparing Inclisiran Versus Statin for Primary Aldosteronism
Primary aldosteronism represents one of the leading causes of resistant hypertension. Circulating cholesterol is established as the exclusive substrate for adrenal aldosterone synthesis, and statins, which suppress cholesterol…
- Trial name
- NCT07884955
- Testing
- inclisiran, Lipophilic statins (such as Simvastatin, Atorvastatin, Fluvastatin, Lovastatin,Pitavastatin), Spironolactone (drug)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Third Military Medical University