Clinical trials: Consciousness, Level Depressed
Alcohol Use Disorder, Inflammatory Response
An Inflammatory Challenge Using Endotoxin
The study design consists of a randomized, double-blind, placebo-controlled trial of low dose endotoxin. The low dose endotoxin challenge induces a transient systemic inflammatory response with normalization of cytokine levels…
- Conditions
- Alcohol Use Disorder, Inflammatory Response, Craving, Depressed Mood
- Trial name
- NCT04310423
- Testing
- Endotoxin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Depression, Suicide
Concurrent Treatment for Depressed Parents and DepressedAdolescents
This study will develop an integrated treatment for adolescents who are depressed and suicidal and their parents who are depressed and have a history of suicidality.
- Trial name
- NCT00951821
- Testing
- Concurrent treatment, Adolescent treatment only
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Brown University
Healthy Volunteers
Performance and Safety of Restylane Lidocaine for Treatment of Depressed Facial Acne Scars
The purpose of this study is to evaluate performance and safety of Restylane Lidocaine for treatment of depressed facial acne scars
- Trial name
- NCT03127384
- Testing
- Restylane Lidocaine, No-treatment control
- Where
- 2 sites in Germany
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Major Depressive Disorder
Study of Repetitive Transcranial Magnetic Stimulation (rTMS) in Depressed Teens
This research study aims to test the safety and effectiveness of repetitive transcranial magnetic stimulation (rTMS) on teens with depression.
- Trial name
- NCT01502033
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Paul E. Croarkin
Tobacco Use Cessation, Tobacco Use Disorder
Effectiveness of Bupropion for Treating Nicotine Dependence in Young People
Little is known about the best ways to help young people stop smoking. Bupropion (a medication marketed as Wellbutrin or Zyban) has proved helpful in treating adult smokers.
- Trial name
- NCT00129272
- Testing
- Bupropion-SR
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Depression, Tobacco Use Disorder
A Behavioral Activation Prenatal and Postpartum Intervention for Depressed Pregnant Smokers
This study evaluates a mood management and health and wellness smoking cessation intervention for depressed pregnant smokers during and after birth.
- Trial name
- NCT05044546
- Testing
- Behavioral Activation Therapy, Discussion, Health Education
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Depression/Depressed State
Drug Use Investigation Of Effexor (SECONDARY DATA COLLECTION STUDY; SAFETY AND EFFICACY OF EFFEXOR.UNDER JAPANESE MEDICAL PRACTICE)
SECONDARY DATA COLLECTION STUDY; SAFETY AND EFFICACY OF EFFEXOR.UNDER JAPANESE MEDICAL PRACTICE
- Trial name
- NCT02958527
- Testing
- venlafaxine
- Volunteers
- 1,408 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Depression, Unipolar
Repeated Neurocognitive Measurements in Depressed Patients
In this project, we will A) track the functioning of a collection of potential neurobiological targets for depression over time, B) examine how fluctuations in the functioning of those targets relates to real-world functioning…
- Trial name
- NCT04916548
- Testing
- Intravenous Ketamine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Rebecca Price
Major Depression
Spirituality Teaching Program for Depressed Adults
Major depression is a widely spread health problem in Canada. Recent research suggests a potential role for religion/spirituality in the prevention of and recovery from depression in adults.
- Trial name
- NCT00322777
- Testing
- Spirituality Teaching Program
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Canadian Institute of Natural and Integrative Medicine
Depression, Quality of Life
Quality of Life and Self-esteem After Botox® Injections in Depressed and Non-depressed Patients
The primary objective of this study is to determine the alterations in quality of life and self-esteem after BOTOX® injections in the glabella in depressed and non-depressed patients.
- Trial name
- NCT01004042
- Testing
- Botulinum Toxin Type A
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hexsel Dermatology Clinic
Depression, Elderly
Telepsychology-Service Delivery for Depressed Elderly Veterans
The purpose of this study is to see whether therapy for elderly adults with major depression can be delivered effectively using videoconferencing technology ("telepsychology"), which allows a therapist and patient who are not in…
- Trial name
- NCT00324701
- Testing
- Telepsychology, Face-to-face therapy
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- US Department of Veterans Affairs
Major Depressive Disorder
Brain Connectivity and Response to Tai Chi in Geriatric Depression
The purpose of this study is to evaluate the effects after up to 1 year of supervised weekly Tai-Chi-Chi versus Health Education and Wellness classes on reduction of depressive symptoms and improvement in resilience, health…
- Trial name
- NCT02460666
- Testing
- Tai-Chi-Chih (TCC), Health Education and Wellness Classes (HEW)
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of California, Los Angeles
MDD
Effect of Bupropion on Seizure Threshold in Depressed Patients
The purpose of the study is to examine the effect of bupropion on seizure threshold and duration in depressed patients receiving right unilateral ultra-brief electroconvulsive therapy (ECT).
- Trial name
- NCT03126682
- Testing
- Wellbutrin SR 300Mg Extended-Release Tablet
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Duke University
Depression
Problem Adaptation Therapy (PATH) vs. Supportive Therapy in Treating Depressed, Cognitively Impaired Older Adults
This study will evaluate the efficacy of Problem Adaptation Therapy (PATH) vs. Supportive Therapy for Cognitively Impaired (ST-CI) older adults in reducing depression and disability in treating depressed, cognitively impaired…
- Trial name
- NCT00368940
- Testing
- PATH, ST-CI
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Weill Medical College of Cornell University
Nicotine Dependence, Major Depressive Disorder
Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers
Persons who struggle with depression smoke at high rates and experience low quit rates in treatment. The best way to improve cessation treatment for this underserved population remains unknown.
- Trial name
- NCT02378714
- Testing
- Varenicline, BASC, Standard treatment
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
HIV Infections, Depression
Bupropion For Reducing High-Risk Behaviors in Depressed Men Who Have Sex With Men (MSM)
The primary purpose of this study was to test the whether high-risk, HIV-seronegative persons with mild-to-moderate depression would be more likely to adopt protective behavior change when provided with pharmacotherapy for their…
- Trial name
- NCT00285584
- Testing
- Bupropion
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- NYU Langone Health
Bipolar I Disorder
Safety and Efficacy of Olanzapine in the Long-term Treatment for Bipolar I Disorder, Depressed
To assess the efficacy and safety of olanzapine in the long-term treatment for patients with bipolar I disorder, depressed.
- Trial name
- NCT00618748
- Testing
- Olanzapine
- Where
- 10 sites in Japan
- Volunteers
- 101 people
- Sponsor
- Eli Lilly and Company
Depression, Self-injurious Behavior
Interpersonal Psychotherapy for Depressed Adolescents Engaging in Non-suicidal Self-injury
The purpose of this study is to examine the feasibility of using Interpersonal Psychotherapy for Depressed Adolescents (IPT-A) to treat adolescents who are experiencing symptoms of depression and are engaging in non-suicidal…
- Trial name
- IPT-ASI (NCT00401102)
- Testing
- Interpersonal Psychotherapy for Depressed Adolescents
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York State Psychiatric Institute
Depression
Preventing Depression in the Children of Depressed African American Mothers
The purpose of the study is to adapt and test the Preventive Intervention Project for urban African American mothers with depression and their children.
- Trial name
- NCT00904917
- Testing
- Prevention Intervention Project, Psychoeducation
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Children's Hospital of Philadelphia
Schizophrenia
Psychosocial Therapy and Risperidone Treatment in Work Performance in Recent-Onset Schizophrenia
This study will determine the effectiveness of various combinations of psychosocial therapy and risperidone treatment in improving work or school performance in people with first-episode schizophrenia.
- Trial name
- NCT00333177
- Testing
- Cognitive remediation training (CT), Healthy behavior training (HBT), Risperidone, administered orally (Oral Ris)
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles