Clinical trials: Consciousness
Cardiopulmonary Failure, Myocardial Infarction (MI)
COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable
The COR-INSIGHT trial aims to evaluate the effectiveness of Peerbridge COR advanced ambulatory ECG wearables (COR 1.0 and COR 2.0) in accurately and non-invasively detecting cardiovascular and cardiopulmonary conditions using…
- Conditions
- Cardiopulmonary Failure, Myocardial Infarction (MI), Heart Decompensation, Heart Failure
- Trial name
- COR-INSIGHT (NCT06763549)
- Testing
- SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Vasovagal Syncope (VVS), Presyncope
A Warning Red Flag Classification System to Predict Risk of Vasovagal Event During Office Hysteroscopy
The goal of this pilot cross sectional study is to identify participants at risk of vasovagal reaction/syncope(VVR/VVS) during office hysteroscopy.
- Trial name
- FLAG-VS (NCT07030218)
- Testing
- Office hysteroscopy
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tanvir Hospital
Disorders of Consciousness
Clinical Evaluation of Chronic Consciousness Disorders Using Resting-state EEG and ERP
Currently, there are significant challenges in the clinical assessment of patients with consciousness disorders, such as distinguishing between vegetative state (VS) and minimally conscious state (MCS), and predicting patient…
- Trial name
- NCT05949528
- Testing
- no intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Risky Behavior
Conscious Awareness Practice in Adolescents
The aim of this study is to reveal the effect of mindfulness on self-efficacy and risky behaviors in adolescents.
- Trial name
- NCT06115343
- Testing
- Mindfulness
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Osmaniye Korkut Ata University
Conscious Sedation
Monitored Anesthesia Care: Dexmedetomidine-Ketamine Versus Dexmedetomidine- Propofol For Chronic Subdural Hematoma
Inadequate sedation and analgesia indicated by intraoperative movements are markers of inadequate MAC during burr-hole surgery for chronic subdural hematoma evacuation especially when general anesthesia poses high risk for the…
- Trial name
- NCT04621526
- Testing
- dexmedetomidine- ketamine, dexmedetomidine- propofol
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Fainting, Presyncope
Evaluation of the Efficiency of Hydration by Isotonic Solution in the Prevent of the Fainting Whole Blood Donors
Blood donation is a generous act carried out by healthy male and female volunteer donors. The safety of blood donation in France is based on rigorous well documented biological and medical criteria, in particular concerning the…
- Conditions
- Fainting, Presyncope, Syncopal Episode
- Trial name
- EVASION (NCT02075099)
- Testing
- tensing exercises, No tensing exercises
- Where
- 2 sites in France
- Volunteers
- 4,825 people, healthy volunteers welcome
- Sponsor
- Etablissement Français du Sang
Prematurity
Are Newborns Conscious of the Placebo Effect? Result From an RCT in Osteopathy
Results from previous studies suggest the association between Osteopathic Manipulative Treatment (OMT) and length of stay (LOS) reduction in a population of preterm infants.
- Trial name
- NCT01852500
- Testing
- Standard care
- Where
- Italy
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- European Institute for Evidence Based Osteopathic Medicine
Craniocerebral Trauma, Traumatic Brain Injury
Effect of Passive Gait Training on the Cortical Activity in Patients With Severe Brain Injury.
The aim of this study is to determine effect of proprioceptive stimulation with passive gait training on the cortical activity in patients with severe brain injury, demonstrated as changes in EEG (electroencephalogram)and ERP…
- Conditions
- Craniocerebral Trauma, Traumatic Brain Injury, Subarachnoid Hemorrhage, Anoxic Brain Injury
- Trial name
- NCT00526500
- Testing
- Tilt Table With Integrated Stepping System
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Consciousness Assessment
New Consciousness Indicators (NCI)
The assessment of the diagnosis and prognosis of patients with disorders of consciousness (DoC) represents a major clinical and ethical challenge, as it may influence therapeutic decision-making.
- Trial name
- NCI (NCT07786298)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Liege
Healthy
Direct Comparison of Altered States of Consciousness Induced by LSD, Psilocybin, and DMT in Healthy Participants
The primary objective of this study is to determine whether equivalent moderately high doses of LSD, psilocybin, and DMT produce qualitatively similar peak effects when the effect duration is standardized with ketanserin.
- Trial name
- LPD (NCT06899334)
- Testing
- LSD, Psilocybin, DMT
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Healthy Volunteers
Neural Correlates of Self
Despite the increasing popularity of mindfulness meditation and hypnosis in healthcare and in the general community the underlying neurobiological mechanisms are unclear.
- Trial name
- NeuCoSe (NCT03206840)
- Testing
- "control", "meditation", "hypnosis".
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Disorder of Consciousness
Metabolic Abnormalities and Intestinal Microecology in Patients With Chronic Disorders of Consciousness
Following severe traumatic brain injury, patients may remain unconscious for many years. It is the intestinal microbiome and metabolomics analysis comparing differentially intestinal microflora and metabolites between patients…
- Trial name
- NCT04530968
- Testing
- No intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Anxiety, Depression
Impact of Complimentary and Alternative Practices on Patient Wellbeing During Rehabilitation
The study's objective is to assess whether CAM methods are feasible and beneficial in the WSRH setting; to assess stress (using the Perceived Stress Scale-14 and using BioSquares™), anxiety (using the Generalized Anxiety…
- Conditions
- Anxiety, Depression, Stress, Pain
- Trial name
- NCT05082246
- Testing
- Conscious Breathing, Heartfulness Meditation, Emotional Freedom Technique
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- WellSpan Health
Brain Injury, Chronic
Investigating the Role of the Premotor Cortex in Higher Cognitive Functions
This project aims at understanding better the role of the frontal lobe of the brain in our capacity to perceive visual information consciously, and also, in our capacity to perceive others' actions.
- Trial name
- NCT00842413
- Where
- France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sexual Health, Sexual Dysfunction, Physiological
The PANHIS Study: Sexual Health in Spanish-Speaking Adults - A Cross-Sectional Online Survey
This cross-sectional observational study uses an online survey to describe the epidemiology of sexual health, sexual behaviour and sexual function in Spanish-speaking adults, and to estimate the prevalence and phenomenology of…
- Conditions
- Sexual Health, Sexual Dysfunction, Physiological, Sexual Dysfunctions, Psychological, Dyspareunia
- Trial name
- PANHIS (NCT07746297)
- Where
- 2 sites in Spain
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Menoclinica by Palacios
Disorder of Consciousness
Transcranial Magnetic Stimulation in Patients With Disorders of Consciousness
Transcranial magnetic stimulation involves the use of alternating magnetic fields to stimulate neurons in the brain.To date, several studies have focused on the use of TMS in patients with impaired consciousness.However,its…
- Trial name
- NCT03385278
- Testing
- rTMS
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Focal Epilepsy, Temporal Lobe Epilepsy
Spatial Scene Recognition Memory in Epilepsy Surgery
This study investigates the anatomical and physiological basis of spatial scene recognition memory in patients with temporal lobe epilepsy and temporal lobe lesions.
- Conditions
- Focal Epilepsy, Temporal Lobe Epilepsy, Medically Refractory Epilepsy, Memory Disorders
- Trial name
- NCT07580183
- Testing
- Virtual Tour Recognition Memory Task, Intracranial EEG Recording with Research Electrodes (Aim III only), MRI Neuroimaging and Neuropsychological Assessment (Aim I)
- Where
- 2 sites in United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Muscle Atrophy
Effectiveness of Egg Versus Whey Protein Powder During Resistance Training
Consumption of whole eggs has recently been shown to stimulate muscle protein synthesis to a greater degree than consumption of egg whites after a resistance training session.
- Trial name
- NCT05206253
- Testing
- Whole egg powder, Whey protein powder
- Where
- 2 sites in Canada
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Cardiac Arrest, Out-Of-Hospital, Angiography
Direct or Subacute Coronary Angiography in Patients With Out of Hospital Cardiac Arrest Without Coma.
In patients with Out-of-Hospital Cardiac arrest who achieves Return Of Spontaneous Circulation (ROSC) The investigators want to evaluate whether there is a benefit from acute Angiography compared to subacute (12-24 hours)…
- Conditions
- Cardiac Arrest, Out-Of-Hospital, Angiography, Percutaneous Coronary Intervention, Coma
- Trial name
- DISCO-noCOMA (NCT04876222)
- Testing
- Acute CAG
- Where
- 7 sites in Denmark, Netherlands
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital Skejby
Mental Energy, Stress
The Cracking Consciousness Study With Monroe & Neuphoria
You've explored the Monroe Focus levels. But, Bob Monroe said, "You might believe something, but you won't understand it until you can measure it with objective data." Now, for the first time, we can measure them.
- Trial name
- NCT07256665
- Testing
- Neuphoria Wearable
- Where
- United States
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- Efforia, Inc