Clinical trials: Consciousness Disorder
Loneliness, Anxiety
Is Signposting to Online Peer Support Helpful in Decreasing Loneliness in Parents of Children With Long-term Conditions and Disabilities?
The present study aims to evaluate whether signposting to online peer support will be associated with a significant decrease in self-reported loneliness for parents of children with long-term conditions and disabilities.
- Conditions
- Loneliness, Anxiety, Anxiety Disorder, Depression
- Trial name
- NCT05373121
- Testing
- Online Peer Support
- Where
- United Kingdom
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University College, London
Nursing Caries, Consciousness, Level Altered
Mindfulness Training in Nurses and Its Effect on Work Stress
The aim of the study, which was planned in the experimental design type, was to determine the effect of the mindfulness-based stress reduction training on nurses' job stress.
- Trial name
- NCT06029205
- Testing
- Conscious Awareness-Based Educatıon, Stress coping training
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Psychological Distress, Anxiety Depression
Psychological Symptoms and Burden in Caregivers of Patients With Disorders of Consciousness
Caregivers of patients with disorders of consciousness are highly prone to developing mental health issues. The aim of this study is to investigate the psychological symptoms and care burden of caregivers of patients with…
- Conditions
- Psychological Distress, Anxiety Depression, Burden, Caregiver, Disorders of Consciousness
- Trial name
- NCT06014476
- Testing
- questionnaires
- Where
- China
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Hangzhou Normal University
Consciousness Disorder
Outcome Prediction in Patients With Acute Disorders of Consciousness
Prior research has indicated a link between outcomes in patients with disorders of consciousness (DOC) and their responses to emotional auditory stimuli.
- Trial name
- NCT04411719
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Disorders of Consciousness
Clinical Evaluation of Chronic Consciousness Disorders Using Resting-state EEG and ERP
Currently, there are significant challenges in the clinical assessment of patients with consciousness disorders, such as distinguishing between vegetative state (VS) and minimally conscious state (MCS), and predicting patient…
- Trial name
- NCT05949528
- Testing
- no intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Disorders of Consciousness
Exploratory Study of Melatonin Induced Sleep Regularization in Severe Brain Injury
Patients with severe brain injuries often have slow accumulating recoveries of function. In ongoing studies, we have discovered that elements of electrical activity during sleep may correlate with the level of behavioral recovery…
- Trial name
- NCT02732288
- Testing
- melatonin
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Depression
An Investigation Into the Effects of Blueberry Anthocyanin on Cognitive Functioning and Mood in Adolescents.
The purpose of this study is to determine whether a 4-week dietary intervention with wild blueberry powder can have an effect on cognitive performance in participants aged between 13-17.
- Trial name
- NCT03119597
- Testing
- Wild Blueberry Powder-13g
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Reading
Coma, Disorder of Consciousness
Development of a Point of Care System for Automated Coma Prognosis
Electroencephalogram/event-related potentials (EEG/ERP) data will be collected from 50 participants in coma or other disorder of consciousness (DOC; i.e., Unresponsive Wakefulness Syndrome [UWS] or Minimally Conscious State…
- Conditions
- Coma, Disorder of Consciousness, Minimally Conscious State, Vegetative State
- Trial name
- NCT03826407
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- McMaster University
Disorder of Consciousness
Personal Music for Disorders of Consciousness
Background: The evaluation and treatment of disorders of consciousness(DOC) is a challenging undertaking. Now many neuroimaging techniques were used to detect the level of consciousness and electroencephagram(EEG) was widely used…
- Trial name
- NCT05382260
- Testing
- Listening to music
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Qiuyou Xie
Disorder of Consciousness
Gamma Entrainment Improve the Recovery of Awareness
The purpose of this study is to elucidate the occurrence of Gamma entrainment and optimize the acousto-optic stimulation parameters to induce it in patients with disorders of consciousness (DOC), to explore the prognostic value…
- Trial name
- NCT05640544
- Testing
- Sound and light stimulation in Gamma band
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Low Mood, Depressive Symptoms
The Effects of Bifidobacterium Longum 1714® in a Population With Low Mood
A randomised, double-blind, placebo-controlled clinical trial to evaluate the effect of 8 weeks of supplementation with Bifidobacterium longum 1714® strain on Beck's Depression Inventory-II Score in adults who experience low mood.
- Trial name
- NCT04925440
- Testing
- Bifidobacterium longum 1714® strain
- Where
- Ireland
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- PrecisionBiotics Group Ltd.
Anxiety, Low Mood
Effectiveness of a School Wellbeing Programme for Internalising Problems in Irish Primary School Children
The aim of this study is to assess the effectiveness of a school-based multi-component universal programme for the reduction of internalising problems (i.e. anxiety and low mood) in primary school pupils.
- Trial name
- NCT05061381
- Testing
- A Lust for Life Schools Programme
- Where
- Ireland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Disorder of Consciousness, Traumatic Brain Injury
Changes in Glutamatergic Neurotransmission of Severe TBI Patients
Studies in patients with disorders of consciousness (DOC) after severe brain injury implicate dysfunction of the anterior forebrain mesocircuit dysfunction a key underlying mechanism.
- Trial name
- NCT04244058
- Testing
- Amantadine + L-DOPA, NMDA blocker
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Anhedonia, Depressed Mood
Depressed Mood and Anhedonia in Healthy Adults
The aim of this study is to evaluate the effect of nutraceutical supplement on depressed mood and anhedonia in volunteers after 8 weeks of consumption.
- Trial name
- MOOD5 (NCT05306093)
- Testing
- Nutraceutical, Maltodextrin
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Anxiety, Fear
An Exploratory Investigation of a CBD Supplement's Impact on Sleep, Stress, and Focus
A high-quality broad-spectrum cannabidiol supplement with a bio-terpene complex will be administered once daily. It is hypothesized that this supplement will lead to improvements in sleep, focus, and stress.
- Conditions
- Anxiety, Fear, Stress, Low Mood
- Trial name
- NCT05518019
- Testing
- The Daily Supplement
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Prima CBD
Disorder of Consciousness, Minimally Conscious State
Simultaneously PET/MRI in Prolonged DOC Patients
Recently introduced hybrid PET/MR scanners provide the opportunity to measure simultaneously, and in direct spatial correspondence, both metabolic demand and functional activity of the brain, hence capturing complementary…
- Conditions
- Disorder of Consciousness, Minimally Conscious State, FDG-PET, Rs-fMRI
- Trial name
- NCT04164680
- Testing
- Multimodal Neuroimaging
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hangzhou Normal University
Disorder of Consciousness
A Promising Tool for Predicting Consciousness Evolution in Prolonged Disorders of Consciousness
The research contains two parts. Part 1: To explore whether EEG responses to zolpidem can assess consciousness circuit integrity and predict the evolution of consciousness in patients with prolonged disorders of consciousness…
- Trial name
- NCT02948660
- Testing
- Zolpidem Tartrate Tablets
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Anxiety, Anxiety Disorders
A Single-session Growth Mindset Intervention for Children and Young People With Mental Health Difficulties
The present study aims to evaluate whether an online, self-administered, single session intervention (SSI) increases children and adolescents' perceptions of control over external threats and their emotional experience and…
- Conditions
- Anxiety, Anxiety Disorders, Depression, Low Mood
- Trial name
- NCT04652362
- Testing
- Growth Mindset Online Single-Session Intervention, Supportive Therapy Online Single-Session Intervention (Control)
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Royal Holloway University
Consciousness Disorder, Brain Injuries
Neurovascular Reactions to AAT in Patients With DOC
There is practical evidence but no scientific investigations that persons with severe disorders of consciousness can profit from animal-assisted therapy regarding their level of awareness.
- Trial name
- AAT NIRS (NCT03341325)
- Testing
- animal-assisted activity, control activity
- Where
- Switzerland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Consciousness Disorders, Locked-In Syndrome
Feasibility of mindBEAGLE in Disorders of Consciousness or Locked-In Syndrome
The primary aims of this study are: 1. To determine the feasibility of deploying mindBEAGLE, a portable, bedside EEG-based system, in the Intensive Care Unit in patients with disorders of consciousness (DOC) or locked-in syndrome…
- Trial name
- NCT02772302
- Testing
- mindBEAGLE EEG-based brain-computer interface
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital