Clinical trials: Consent
Colorectal Cancer Screening
Does Numerical And Pictorial Information On Risk And Benefit Affects The Uptake Of Colorectal Cancer Screening?
To establish whether provision of numerical data, framed as event rates and illustrated by pictograms, and including figures for all-cause mortality, affects subjects' attitudes to colorectal cancer (CRC) screening.
- Trial name
- NCT01250015
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- County Durham and Darlington NHS Foundation Trust
Scleroderma
Empirical Comparative Study of Variation Blood Level Antibody Vitamin D at Scleroderma (SSc) Patients Compared Healthy Peoples
The aim is to find the presence of anti vitamin D antibodies in scleroderma patients and compare with control. A second goal is anti vitamin D levels in serum of scleroderma patients in relation to the clinical manifestations of…
- Trial name
- SSc (NCT01553890)
- Testing
- Blood sample
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Critical Care Trial Participation Consent by SDM
The Approach Study
In the Approach Study, the investigators will study the 'process' by which Substitute Decision Makers (SDMs) are approached for consent for their loved one's participation in critical care research.
- Trial name
- NCT01232621
- Testing
- Physician Introduction of research personnel
- Where
- Canada
- Volunteers
- 138 people
- Sponsor
- Unity Health Toronto
Alzheimer Disease
Enhancing Consent for Alzheimer's Research
The purpose of this study is to evaluate the efficacy of an enhanced consent procedure for patients with mild-to-moderate Alzheimer disease, and to identify factors and patient characteristics that predict the degree to which…
- Trial name
- BWP-AD (NCT00453544)
- Testing
- Enhanced Consent Procedure, Routine Consent Procedure
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Informed Consent, Comprehension
AI-Driven Consent Simplification Study
The overarching goal of this pilot is to explore how generative artificial intelligence (genAI) can be used to improve the accessibility and understandability of informed consent materials in clinical research.
- Conditions
- Informed Consent, Comprehension, Communication, Disclosure
- Trial name
- ACCESS (NCT07303517)
- Testing
- Original ICF, AI Simplified ICF, Podcast - Original ICF
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Cataract
Computer-based Tutorial for the Informed Consent Process for Cataract Surgery in Turkish or Serbian Speaking Patients
Investigate if a computer-based tutorial enhances the quality and efficiency of the informed consent process for cataract surgery in Turkish or Serbian speaking patients.
- Trial name
- NCT03748368
- Testing
- Cataract presentation
- Where
- Austria
- Volunteers
- 72 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Satisfaction, Risk Reduction
Electronic Confirmed Versus Conventional Consenting Process: A Randomized Controlled Trial
· The target population for our study is women who present in their last clinic visit before delivery and are scheduled for an elective cesarean section.
- Trial name
- ECCCO (NCT03510260)
- Testing
- Study Group I, Study Group II, Control Group
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Congestive Heart Failure, Infections
Does Detailed Informed Consent for Cardiopulmonary Resuscitation and Mechanical Ventilation Impact Patients' Decisions and Outcomes?
There is evidence to suggest that patients make different end-of-life decisions if they understand the risks, benefits and alternatives of CPR and mechanical ventilation.
- Conditions
- Congestive Heart Failure, Infections, Sepsis, Acute Renal Failure
- Trial name
- NCT01878968
- Testing
- Script and CPR/Mechanical ventilation video.
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Jewish Hospital, Cincinnati, Ohio
Urinary Incontinence, Pelvic Organ Prolapse
Effect of Standardized Consent for Urogynecological Procedures on Patient Satisfaction
The investigators aim is to augment the current process for surgical consent for patients undergoing urogynecological procedures by incorporating visual media.
- Trial name
- NCT02313701
- Testing
- Standardized visual presentation
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Alzheimer Disease, Neurodegenerative Diseases
Decision-making, Ethical Consent, and Interactive Dialogue in Ongoing Neurocognitive Decline - DECISION
DECISION Study - Summary Title: Decision-making, Ethical Consent, and Interactive Dialogue in Ongoing Neurocognitive Decline The DECISION study aims to develop and validate a simplified yet robust tool for assessing the capacity…
- Trial name
- DECISION (NCT07514520)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Stroke
Information Recall on Informed Consent to Intravenous Thrombolysis in Patients With Acute Ischaemic Stroke.
The aim of the study is to investigate the ability to recall information given during informed consent on intravenous thrombolysis in patients with acute ischaemic stroke.
- Trial name
- NCT03246256
- Testing
- Group 1
- Where
- 5 sites in Germany
- Volunteers
- 260 people
- Sponsor
- Charite University, Berlin, Germany
Hyperlipidemia, Hypercholesterolemia
Patient and Provider Assessment of Lipid Management Registry
The purpose of the Patient and Provider Assessment of Lipid Management Registry (PALM) is to gain a better understanding of physicians' cholesterol medication prescribing practices, patient and physician attitudes and beliefs…
- Conditions
- Hyperlipidemia, Hypercholesterolemia, Cardiovascular Disease, Diabetes
- Trial name
- PALM (NCT02341664)
- Where
- 14 sites in United States
- Volunteers
- 7,658 people
- Sponsor
- Duke University
Premalignant Conditions, Malignant Lesions
To Evaluate the Best Metric for Inspection Time During a Diagnostic and/or Surveillance Upper Gastrointestinal Endoscopy (Age ≥ 18 Years, Informed Consent), Between Total Inspection Time Versus Withdrawal Time, for the Identification of Malignant Lesions
Gastric cancer is the fifth cause of cancer-related mortality worldwide. Gastric carcinogenesis involves the progression from premalignant conditions such as atrophic gastritis and intestinal metaplasia to premalignant lesions…
- Conditions
- Premalignant Conditions, Malignant Lesions, Gastric, Esophageal
- Trial name
- NCT06696209
- Testing
- Analysis of the withdrawal time of the Upper Gastrointestinal Endoscopy, Analysis of the total time of the Upper Gastrointestinal Endoscopy, Upper gastrointestinal endoscopy: Common Practices
- Where
- Portugal
- Volunteers
- 1,290 people, healthy volunteers welcome
- Sponsor
- Portuguese Oncology Institute, Coimbra
Dental Anxiety
Effects of Consent Methods Performed According to Intelligence Types on Anxiety Associated with Third Molar Surgery
The aim of this study is to investigate the effect of information provided in accordance with intelligence type on anxiety associated with wisdom tooth surgery.
- Trial name
- NCT04613947
- Testing
- Informed consent, Third molar surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ordu University
Breast Cancer
REaCT Integrated Consent Model to Compare Two Standard of Care Regimens
The Integrated Consent Model is being increasingly used internationally to improve patient care. In this feasibility study we will explore whether the model is feasible in practice; and whether it can be used to increase the…
- Trial name
- OTT14-03 (NCT02173262)
- Testing
- G-CSF, Ciprofloxacin
- Where
- Canada
- Volunteers
- 142 people
- Sponsor
- Ottawa Hospital Research Institute
Bariatric Surgery Candidate
Video-Assisted Presentation Before Bariatric Surgery Enhanced Understanding of Informed Consent Content
This study evaluates the addition of video presentation on conventional informed consent. Participants divided two randomly, one group read only conventional informed consent, the other video presentation was watched after…
- Trial name
- NCT03653962
- Testing
- video assisted group, non-video group
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Inonu University
Informed Consent
Patients' Comprehension and Internalization of Operative Consent Form
This is a prospective pilot study conducted within otolaryngology (ENT) clinics in a tertiary hospital between July and December 2016.
- Trial name
- NCT04627597
- Volunteers
- 22 people
- Sponsor
- Singapore General Hospital
Adult Patients Ventilated More Than 48 h, Stable Respiratory and Hemodynamic Conditions for SBT
Nasal Humidified High Flow Oxygen During Weaning From Mechanical Ventilation : Ultrasonography Study
This is a prospective, randomized clinical multicentric study in ICU (Intensive Care University)during weaning from mechanical ventilation.
- Conditions
- Adult Patients Ventilated More Than 48 h, Stable Respiratory and Hemodynamic Conditions for SBT, Consent of Patients, Arterial Line
- Trial name
- HiFloLUS (NCT01702779)
- Testing
- mechanical ventilation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Condomless Sex, Sexual Assault
Evaluating a Digital Intervention to Improve Adolescent Condom Use and Communication
The purpose of this study is to test the effectiveness, likability, and implementation potential of PACT, an adapted digital program to teach non-heterosexual adolescent boys about sexual consent and condom negotiation in a…
- Trial name
- NCT06878755
- Testing
- Promoting Assertive Communication among Teens (PACT), Healthy Minds
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- North Carolina Agriculture & Technical State University
Consent, Laparoscopic
Optimizing the Consent Process for Emergent Laparoscopic Cholecystectomy
The Canadian Medical Protective Association (CMPA) defines informed consent (IC) as a voluntary process where important elements include details of the procedure, complications, and proposed alternatives.
- Conditions
- Consent, Laparoscopic, Cholecystectomy
- Trial name
- NCT04852016
- Testing
- Consent process with the addition of Digital educational platform (DEP), Consent process using the standard verbal consent (SVC)
- Where
- Canada
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Dr. Boris Zevin