Clinical trials: Constipation
Healthy, Constipation
Dairy Products to Your Gut and Brain
The goal of this intervention study is to compare the effects of fermented dairy and non-fermented dairy on bowel habits and cognitive performance in healthy women with defecations every other day or less.
- Trial name
- YourGutBrain (NCT06311097)
- Testing
- Fermented dairy, Non-fermented dairy
- Where
- Denmark
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Constipation, Diarrhea
Efficacy of a Dietary Supplementation With Lactobacillus Reuteri for Digestive Health in an Elderly Population
The purpose of this study is to investigate the effect of a daily supplement consisting of the probiotic bacteria, Lactobacillus reuteri, on the digestive health among persons 65 years and older.
- Conditions
- Constipation, Diarrhea, Indigestion, Reflux
- Trial name
- NCT01837940
- Testing
- Lactobacillus reuteri DSM 17938
- Where
- Sweden
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Postoperative Constipation, Pelvic Organ Prolapse Vaginal Surgery
Impact of Defecation Posture on Ease of First Bowel Movement Following Posterior Repair
This study will determine if defecation posture, when using a defecation posture modification device (DPMD), improves ease with first bowel movement following pelvic reconstructive surgery, specifically posterior repair.
- Conditions
- Postoperative Constipation, Pelvic Organ Prolapse Vaginal Surgery, Defecation Function
- Trial name
- NCT06253689
- Testing
- Defecation Posture Modification Device
- Where
- 3 sites in United States
- Volunteers
- 160 people
- Sponsor
- TriHealth Inc.
Constipation, Advanced Cancer
Effect of Laser Acupuncture on Constipation in Patients With Advanced Cancer
Constipation is one of the most common complications in patients with advanced cancer. The aim of this protocol designed as a double-blind randomized controlled trial is to investigate the efficacy of laser acupuncture (LA)…
- Trial name
- NCT04318808
- Testing
- Laser acupuncture
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Constipation, Irritable Bowel Disease
Relationship Between Interoception and Postural Control in Constipation-Predominant Irritable Bowel Syndrome
This cross-sectional, observational, controlled comparative study aims to investigate the relationship between interoception and postural control in individuals with constipation-predominant irritable bowel syndrome (IBS-C) and…
- Trial name
- NCT07870915
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Infantile Colic, Constipation - Functional
Bowel And Bladder Function in Infant Toilet Training
The overall purpose is to assess whether assisted infant toilet training during the first year of life can prevent functional gastrointestinal and urinary tract disorders up to 4 year of age.
- Conditions
- Infantile Colic, Constipation - Functional, Bladder Dysfunction, Toilet Training
- Trial name
- BABITT (NCT04082689)
- Testing
- Assisted Infant Toilet Training
- Where
- 6 sites in Sweden
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- Dalarna County Council, Sweden
Constipation
Effectiveness of Non-invasive Neuromodulation for Intestinal Transit in Healthy Subjects
Objectives Main objective: Assess the effectiveness of non-invasive neuromodulation treatment (NESA) for the management of constipation in patients without diagnosed pathology in Spain Secondary objectives: Evaluate the…
- Trial name
- NCT06294457
- Testing
- Non-Invasive Neuromodulation NESA
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Constipation - Functional
Lubiprostone in Children With Functional Constipation
Study to determine if children (6-17 years old) with functional constipation will respond to being treated with lubiprostone for 12 weeks.
- Trial name
- NCT02042183
- Testing
- Lubiprostone
- Where
- 117 sites in United States, Belgium and 5 more
- Volunteers
- 606 people
- Sponsor
- Sucampo Pharma Americas, LLC
Colon Cancer, Colon Diverticulosis
Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery
The General Objective of this study is to investigate the cost and efficacy of treating patients undergoing colorectal surgical resections with an opioid limited pain control regimen as part of an Enhanced Recovery After Surgery…
- Conditions
- Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis
- Trial name
- NCT02958566
- Testing
- Acetaminophen, Gabapentin, Orphenadrine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Illinois College of Medicine at Peoria
Constipation
An Observational Study to Evaluate the Quality of Life in Korean Female Participants With Chronic Constipation
The purpose of this observational study is to investigate health related quality of life (QoL) in Korean female participants with chronic constipation (long term decreased number of or difficulty making bowel movements) having…
- Trial name
- NCT01902537
- Testing
- Prucalopride; observational study
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Janssen Korea, Ltd., Korea
Gut Health
A Study to Evaluate the Effects of a Butyrate-Polyphenol Formulation on Gut Health and Associated Symptoms
The purpose of the study is to evaluate the efficacy of a butyrate/polyphenol formulation on modulation of the gut microbiome and gastrointestinal symptoms using questionnaires in individuals with self-reported gastrointestinal…
- Trial name
- NCT07371975
- Testing
- Butyrate + Polyphenol Formulation
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Chronic Constipation
Comparing Manual and Automatic Colonic Massage for Chronic Constipation.
The aim of this study is to do a systematic review and metanalysis of the scientific literature to compare the effectiveness of the manual vs the automatic colonic massage intervention in patients with chronic constipation.
- Trial name
- COMACOMACC (NCT06695754)
- Where
- Spain
- Volunteers
- 2,312 people
- Sponsor
- usMIMA S.L.
Constipation
Xuanhuang Runtong Tablet in the Treatment of Constipation (Yin-deficiency Type)
This trial is a randomized, double-blind, placebo-controlled parallel-group, multicenter Phase III clinical trial. It is to evaluate the efficacy and safety of Xuanhuang Runtong Tablets in subjects with constipation…
- Trial name
- XHRT (NCT06740422)
- Testing
- Xuanhuang Runtong Tablet, Xuanhuang Runtong Tablet Simulator
- Volunteers
- 300 people
- Sponsor
- Beijing Hospital of Traditional Chinese Medicine
Irritable Bowel Syndrome-IBS
Effect of Different Dietary Therapies on Intestinal Barrier Integrity in Patients With Irritable Bowel Syndrome
This study aims to evaluate the effects of different dietary treatments on intestinal integrity in female subjects aged 19-50 years previously diagnosed with constipation-predominant irritable bowel syndrome (IBS).
- Trial name
- NCT06421922
- Testing
- Group 1 received a regular constipation diet, Group 2 received a constipation diet rich in soluble fiber, Group 3 received a constipation diet supplemented with probiotic yogurt.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gulhane Training and Research Hospital
Chronic Idiopathic Constipation
Evaluation of the Bioequivalence of Sprinkle and Capsule Formulations of Lubiprostone, as Compared to Placebo
The purpose of this study is to evaluate the bioequivalence of sprinkle and capsule formulations of lubiprostone, as compared to placebo, when administered orally in participants with Chronic Idiopathic Constipation (CIC).
- Trial name
- NCT03097861
- Testing
- Lubiprostone
- Where
- 67 sites in United States
- Volunteers
- 552 people
- Sponsor
- Sucampo Pharma Americas, LLC
Constipation
Soy Polysaccharide Fiber for the Treatment of Chronic Constipation in Children: a Randomized, Double-blind Trial
The study tested the hypothesis that soy polysaccharide fiber reduces clinical symptoms of chronic constipation.
- Trial name
- SOYFIBER (NCT01267370)
- Testing
- Soy polysaccharide fiber
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Constipation
Oat Milk for Laxation
This study intends to recruit 90-100 constipated participants aged 25-50 years, including an equal number of males and females, from the faculty and logistics staff of Capital Medical University.
- Trial name
- NCT07302542
- Testing
- oat milk
- Where
- China
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Failure to Thrive, Nutritional Deficiency
Nasogastric Tube Securement Comparison Study
This study evaluates the use of tape to secure nasogastric tubes compared to securement with a nasal bridle device.
- Conditions
- Failure to Thrive, Nutritional Deficiency, Constipation, Bowel Obstruction
- Trial name
- NTSNB (NCT03202576)
- Testing
- Nasal Bridle
- Volunteers
- 43 people
- Sponsor
- University of Colorado, Denver
Constipation
Bowel Function After Minimally Invasive Hysterectomy
Postoperative constipation affects up to a third of women undergoing minimally invasive (MIS) gynecologic surgery and is a major source of anxiety and discomfort.
- Trial name
- NCT04263896
- Testing
- Polyethylene Glycol 3350
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Cognitive/Functional Effects, Constipation, Impaction, and Bowel Obstruction
Probiotic Therapy in Preventing Gastrointestinal Complications in Patients Undergoing Chemotherapy and Pelvic Radiation Therapy
RATIONALE: Probiotic therapy may reduce or prevent gastrointestinal complications in patients undergoing chemotherapy and pelvic radiation therapy.
- Conditions
- Cognitive/Functional Effects, Constipation, Impaction, and Bowel Obstruction, Diarrhea, Fatigue
- Trial name
- NCT01473290
- Testing
- live freeze-dried lactic acid bacteria probiotic
- Sponsor
- Alliance for Clinical Trials in Oncology