Clinical trials: Constipation, completed
Constipation
Outpatient Treatment of Constipation in Children
Constipation is a condition often seen in children. Constipation is often associated with impaired quality of life of the child and of great concern among parents.
- Trial name
- NCT01582659
- Testing
- Telephone counseling, Web access
- Where
- 2 sites in Denmark
- Volunteers
- 239 people
- Sponsor
- Line Modin
Constipation
Bowel Function After Minimally Invasive Hysterectomy
Postoperative constipation affects up to a third of women undergoing minimally invasive (MIS) gynecologic surgery and is a major source of anxiety and discomfort.
- Trial name
- NCT04263896
- Testing
- Polyethylene Glycol 3350
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Irritable Bowel Syndrome With Constipation (IBS-C)
A Phase 3, International, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Trial of Linaclotide Administered Orally for 12 Weeks to Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
This clinical trial is an international, multicenter, randomized, double-blind, placebo-controlled, parallel-group trial comparing one dose of linaclotide to placebo.
- Trial name
- D5630C00001 (NCT01880424)
- Testing
- Linaclotide
- Where
- 82 sites in United States, Australia and 3 more
- Volunteers
- 1,722 people
- Sponsor
- AstraZeneca
Stool Assessment, Skin Rash
GI Symptoms in Infants Fed Goat Milk-based Infant Formula
A cross-sectional observational survey was conducted in Brazil, Mexico, Russia, and The Netherlands by recruiting parents/legal guardians through social media.
- Conditions
- Stool Assessment, Skin Rash, Urticaria, Regurgitation
- Trial name
- NCT06755424
- Where
- Netherlands
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Ausnutria Hyproca B.V.
Chronic Constipation
A Study of Oral Dosing of ASP0456 in Patients With Chronic Constipation
The objective of this study is to verify the efficacy and investigate the safety of the study drug when ASP0456 is administered orally for 4 weeks and 52 weeks.
- Trial name
- NCT02809105
- Testing
- linaclotide
- Where
- 39 sites in Japan
- Volunteers
- 186 people
- Sponsor
- Astellas Pharma Inc
Constipation Chronic Idiopathic
Vibrant Capsule vs. Placebo for Patient Suffering From Constipation
The objectives are to assess the efficacy and safety of Vibrant capsule administered twice a week
- Trial name
- Capsule (NCT05036369)
- Testing
- Vibrant capsule
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Vibrant Ltd.
Constipation
Abdominal Massage for People With Learning Disabilities and Constipation
Background and study aims: Constipation, which is difficulty going to the toilet to do a 'poo' is common in adults with learning disabilities (LD), but there is not a lot of knowledge (information) about the best way to help…
- Trial name
- AMID (NCT05490654)
- Testing
- Abdominal Massage
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Glasgow Caledonian University
Parkinson's Disease, Constipation
Evaluation of Safety and Tolerability of ENT-01 for the Treatment of Parkinson's Disease Related Constipation
This is a Phase 1/2a study to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of an orally-administered medication to relieve symptoms of constipation associated with Parkinson's Disease.
- Trial name
- RASMET (NCT03047629)
- Testing
- ENT-01
- Where
- 15 sites in United States
- Volunteers
- 50 people
- Sponsor
- Enterin Inc.
Constipation, Surgical Treatment
To Explore the Efficacy and Safety of Surgical Treatment for Constipation, as Well as the Changes of Postoperative Intestinal Motility, Flora, Nutritional Status and Other Indicators
Chronic constipation is a heterogeneous disease with multiple symptoms, and its incidence is on the rise in many countries. It has become a common disease affecting the quality of life.
- Trial name
- NCT05983926
- Testing
- Subtotal colectomy was performed
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai 10th People's Hospital
Constipation-predominant Irritable Bowel Syndrome (IBS-C)
A Study to Evaluate the Effect of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome
This study is to investigate the efficacy, safety, and plasma concentration change of ASP0456 in patients with constipation-predominant irritable bowel syndrome.
- Trial name
- NCT01714843
- Testing
- linaclotide
- Where
- 4 sites in Japan
- Volunteers
- 559 people
- Sponsor
- Astellas Pharma Inc
Constipation, Abdominal Massage
Effect of Abdominal Massage on Bowel Evacuation After Cranial Surgery
Many factors in patients undergoing cranial surgery (CS) may affect the bowel evacuation of patients, resulting in constipation, which could lead to the use of the valsalva maneuver.
- Trial name
- NCT04373772
- Testing
- abdominal massage
- Volunteers
- 80 people
- Sponsor
- Mersin University
Constipation
Trial of Alvimopan in Major Spine Surgery
The Investigator has chosen to study the reconstructive spinal surgery patient population because it is believed that the use of alvimopan in these patients at the University of Virginia will give the scientific community…
- Trial name
- NCT02789111
- Testing
- Alvimopan
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Virginia
Opioid Induced Bowel Dysfunction
Study to Evaluate the Safety and Efficacy of Naldemedine (S-297995) for the Treatment of Opioid-Induced Bowel Dysfunction in Subjects With Chronic Pain
The primary objective of the study is to evaluate the safety of single doses of oral naldemedine in adults physically dependent on opioids.
- Trial name
- NCT01122030
- Testing
- Naldemedine
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Shionogi
Constipation
A Dose Determination Study of Chinese Herbal Medicine for Functional Constipation
Functional constipation (FC) is common with 14.3% estimated prevalence in Hong Kong, but treatment for this condition in conventional medicine is suboptimal.
- Trial name
- NCT00299975
- Testing
- MaZiRenWan (MZRW) Low dose, MaZiRenWan (MZRW) Median dose, MaZiRenWan (MZRW) High dose
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Hong Kong Baptist University
Idiopathic Parkinson's Disease, Constipation
The Effectiveness of Biofeedback Treatment in Constipated Patients With Idiopathic Parkinson's Disease
The aims of the investigators' study are to characterize the nature of constipation in idiopathic Parkinson's disease (IPD) and to evaluate the usefulness of biofeedback therapy in constipated IPD patients.
- Trial name
- NCT00869830
- Testing
- biofeedback therapy
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Constipation
Itopride as an Adjuvant for Bowel Preparation in Patients With Chronic Constipation is Effective
Bowel preparation is a major determinant of colonoscopy and colorectal surgery. Polyethylene glycol electrolyte solutions (PEG-E) are the most commonly used laxatives in China.
- Trial name
- NCT01513811
- Testing
- Polyethylene glycol electrolyte solutions, Itopride and Polyethylene glycol electrolyte solutions
- Where
- China
- Volunteers
- 115 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Constipation - Functional
Study on the Effect of Rhubarb Extract on Stool Frequency and Biological Markers of Intestinal Function in Seniors With Low Defecation
Randomized double-blind clinical study versus placebo evaluating the effect of supplementation with rhubarb extract on stool frequency and biological markers of intestinal function in seniors with a low number of defecations per…
- Trial name
- NCT05541991
- Testing
- single dose coated tablet Fruits & Fibres Rhubarbe with standardised rhubarb extract, double dose coated tablet Fruits & Fibres Rhubarbe with standardised rhubarb extract
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ortis
Functional Constipation
The Effect of Probiotics on Functional Constipation in the Elderly
The main scope of the proposed research in the framework is to investigate the effect of probiotic bacteria Lactobacillus acidophilus LA3, Bifidobacterium animalis ssp.
- Trial name
- NCT04506801
- Testing
- Probalans senior
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Katarina Fehir Šola
Constipation
Randomised Controlled Trial of Efficacy of Resistant Maltodextrins on Reducing Colonic Transit Time
The purpose of this study is to assess the efficacy of resistant maltodextrins, compared to placebo, in reducing the colonic transit time in healthy subjects.
- Trial name
- NCT01802112
- Testing
- Resistant maltodextrins
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- San Antonio Technologies - San Antonio Catholic University of Murcia
Chronic Idiopathic Constipation
Lubiprostone for Treatment of Chronic Idiopathic Constipation
The purpose of this study was to evaluate the efficacy and safety of oral administration of lubiprostone 24 μg twice daily (BID) for 4 weeks in participants with chronic idiopathic constipation (CIC) compared with placebo.
- Trial name
- NCT02695719
- Testing
- Lubiprostone
- Where
- 5 sites in South Korea
- Volunteers
- 156 people
- Sponsor
- Takeda