Clinical trials: Constipation, completed
Functional Constipation
Study of NGM282 in Subjects With Functional Constipation and Healthy Individuals
The purpose of this study is to determine the effect of NGM282 on colonic transit, bile acid homeostasis, and fecal fat in subjects with functional constipation and healthy individuals.
- Trial name
- NCT02649062
- Testing
- NGM282
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- NGM Biopharmaceuticals, Inc
Constipation Predominant Irritable Bowel Syndrome
The Efficacy of AZD1722 in Constipation Predominant Irritable Bowel Syndrome (IBS-C)
This phase 2, randomized, double blind, placebo-controlled, multi-center study will evaluate the safety and efficacy of three dose levels of AZD1722 in subjects with constipation predominant IBS (IBS-C) as defined by the ROME III…
- Trial name
- NCT01923428
- Testing
- AZD1722
- Where
- 4 sites in United States
- Volunteers
- 356 people
- Sponsor
- Ardelyx
Constipation
The Bowel Research Collaborative Data Tracking System Implementation Study
The project's primary purpose is to establish a network of Hospice Palliative Care settings using a common and consistent method of assessing and documenting bowel functioning in order to be able to carry out future collaborative…
- Trial name
- NCT00728975
- Where
- Canada
- Volunteers
- 533 people
- Sponsor
- British Columbia Cancer Agency
IBS, Constipation
Optimization of Transcutaneous Electrical Acustimulation (TEA) Modalities for Treatment of IBS-C
This study aims to determine the most effective treatment with Transcutaneous Electrical Acustimulation (TEA) for Irritable Bowel Syndrome with Constipation (IBS-C) by comparing efficacy between 5 separate sessions.
- Trial name
- TEA (NCT04953728)
- Testing
- Transcutaneous Electrical Acustimulation (TEA)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Michigan
Opioid-induced Constipation
Efficacy and Safety of Naldemedine in Treating Opioid-induced Constipation
The purpose of this study is to evaluate the efficacy and safety of naldemedine in the treatment of opioid-induced constipation (OIC) in adults with non-malignant chronic pain who are not using laxatives.
- Trial name
- NCT01993940
- Testing
- Naldemedine
- Where
- 49 sites in United States
- Volunteers
- 553 people
- Sponsor
- Shionogi
Constipation Predominant Irritable Bowel Syndrome
A 26-Week Study to Evaluate the Efficacy and Safety of Tenapanor in IBS-C
This phase 3, 26-week, randomized, double-blind, placebo-controlled, multi-center study will evaluate the safety and efficacy of one dose of Tenapanor in subjects with constipation-predominant irritable bowel syndrome (IBS-C) as…
- Trial name
- T3MPO-2 (NCT02686138)
- Testing
- Tenapanor
- Where
- 117 sites in United States
- Volunteers
- 593 people
- Sponsor
- Ardelyx
Constipation
Foot Reflexology and Abdominal Massage
to determine and compare the effects of foot reflexology and abdominal massage applied to elderly individuals on constipation
- Trial name
- experimental (NCT06875349)
- Testing
- foot reflexology, abdominal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Karadeniz Technical University
Massage
Massage With Senna-based Laxatives Versus Senna-based Laxatives in Managing Overflow Retentive Stool Incontinence
This study aimed to evaluate the effect of abdominal massage with senna-based laxative in managing overflow retentive stool incontinence in pediatrics.
- Trial name
- NCT04273295
- Testing
- Abdominal massage
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- South Valley University
Functional Constipation
Visceral Osteopathy in Functional Constipation
It is a functional bowel disease characterized by excessive straining during defecation, infrequent defecation, and the feeling of incomplete evacuation.
- Trial name
- NCT06196073
- Testing
- Osteopathic manual therapy, conservative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Pamukkale University
Constipation - Functional
PHGG-LGG Synbiotic in Pediatric Functional Constipation
This prospective, randomized controlled open-label trial evaluated the efficacy of a synbiotic consisting of partially hydrolyzed guar gum (PHGG) and Lacticaseibacillus rhamnosus GG (LGG) on clinical outcomes and gut microbiota…
- Trial name
- PHGG-LGG-FC (NCT07580729)
- Testing
- 4.3 g partially hydrolyzed guar gum 1×10⁹ CFU Lacticaseibacillus rhamnosus GG, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Eskisehir Osmangazi University
Autism Spectrum Disorder
Efficacy of Vivomixx on Behaviour and Gut Function in Autism Spectrum Disorder
The purpose of this study is to assess the effects of 3 months supplementation with the multi strain probiotic Vivomixx on the overall function, aberrant behaviours and frequency of gastrointestinal symptoms in children with…
- Trial name
- VIVO-ASD (NCT03369431)
- Testing
- Vivomixx
- Where
- United Kingdom
- Volunteers
- 69 people
- Sponsor
- University College, London
Constipation, Stroke
Auricular Acupuncture for Post-Stroke Constipation
The goal of this clinical trial is to learn if auricular acupuncture can improve constipation in hospitalized patients with post-stroke constipation.
- Conditions
- Constipation, Stroke, Post-stroke Constipation
- Trial name
- NCT07751224
- Testing
- Auricular Acupuncture
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Ho Chi Minh City Orthopedics and Rehabilitation Hospital
Diarrhea, Constipation
Probiotics and Hospital Outcome in the Elderly
Probiotics have been shown to reduce the rate of diarrhea and constipation. The purpose of this study was to investigate if probiotics could improve outcome of hospitalized orthopedic elderly patients.
- Trial name
- PROAGE (NCT00794924)
- Testing
- VSL#3
- Volunteers
- 345 people
- Sponsor
- Kaplan-Harzfeld Medical Center
Constipation, Lower Extremity Surgery
Ear Massage Effect on Bowel Activity After Surgery
Constipation is seen in patients undergoing orthopedic surgical interventions at rates as high as 23% to 94%. Constipation develops more frequently in individuals undergoing major orthopedic surgical interventions such as lower…
- Trial name
- NCT06862986
- Testing
- Ear massage
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Mersin University
Constipation
Study Evaluating Long-Term Safety of MOA-728 in Participants With Opioid-Induced Constipation
This study is designed to evaluate the long-term safety and tolerability of the subcutaneous (SC) injection form of N-methylnaltrexone bromide (MOA-728) for the treatment of opioid-induced constipation in participants with…
- Trial name
- NCT00804141
- Testing
- N-methylnaltrexone bromide (MOA-728)
- Where
- 120 sites in United States, Australia and 4 more
- Volunteers
- 1,040 people
- Sponsor
- Bausch Health Americas, Inc.
Opioid-induced Constipation in Patients With Cancer
Effect of Electroacupuncture on Opioid-induced Constipation in Patients With Cancer
Approximately 70-80% of patients with advanced disease will be affected by moderate to severe pain. Opioid analgesics represented by morphine and oxycodone are the cornerstone of cancer-pain management, and recommended for use in…
- Trial name
- NCT03797586
- Testing
- Electroacupuncture group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Constipation
Outpatient Treatment of Constipation in Children
Constipation is a condition often seen in children. Constipation is often associated with impaired quality of life of the child and of great concern among parents.
- Trial name
- NCT01582659
- Testing
- Telephone counseling, Web access
- Where
- 2 sites in Denmark
- Volunteers
- 239 people
- Sponsor
- Line Modin