Clinical trials: Constipation Drug Induced
Constipation Drug Induced
Prevention of Constipation in Cancer Patients
Constipation is the third most common symptom in patients undergoing chemotherapy, with an incidence rate ranging from 31% to 90%.
- Trial name
- NCT07007468
- Testing
- Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Can Lafci
Constipation, Psychiatric Drug Induced Constipation
Effectiveness of Self-administered Acupressure Intervention in Managing Constipation of Adult Psychiatric Out-patient
Constipation is a common gastrointestinal condition characterised by unsatisfactory defecation as a result of infrequent stools, difficult stool passage or both.
- Conditions
- Constipation, Psychiatric Drug Induced Constipation, Constipation Drug Induced
- Trial name
- NCT07039409
- Testing
- Acupressure
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- Hong Kong Metropolitan University
Constipation, Psychiatric Drug Induced Constipation
Effectiveness of Self-Administered Acupressure Intervention in Managing Constipation of Adult Psychiatric In-Patient
Constipation is a common gastrointestinal condition characterized by unsatisfactory defaecation as a result of infrequent stools, difficult stool passage, or both.
- Conditions
- Constipation, Psychiatric Drug Induced Constipation, Constipation Drug Induced
- Trial name
- NCT07039448
- Testing
- Acupressure
- Where
- Hong Kong
- Volunteers
- 154 people
- Sponsor
- Hong Kong Metropolitan University
Constipation Drug Induced
Methylnaltrexone vs Naloxegol in the Treatment of Opioid-Induced Constipation
The purpose of this study is to compare the efficacy of subcutaneous versus oral mu-opioid receptor antagonist therapy in opioid induced constipation that is refractory to other bowel regimens.
- Trial name
- NCT03523520
- Testing
- Methylnaltrexone Bromide 150 mg Oral Tablet, Methylnaltrexone Bromide 12 MG/0.6 ML Subcutaneous Solution [RELISTOR]_#1, Naloxegol 25 MG Oral Tablet
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Missouri-Columbia
Constipation, Constipation Drug Induced
Naloxegol and Opioid-induced Constipation
This is a double-blind, randomized, placebo-controlled trial to examine the effectiveness of adding one 25mg dose of naloxegol to the cardiac surgery pre-operative regimen.
- Trial name
- NCT03316859
- Testing
- Naloxegol 25 MG
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- TriHealth Inc.
Opioid Use, Constipation Drug Induced
Study on Quality of Life in Advanced Cancer Patients With Opioid-induced Constipation Treated With Naloxegol
Opioid-Induced Constipation (OIC) is often associated with a compromised quality of life of patients in palliative care (PC) setting.
- Conditions
- Opioid Use, Constipation Drug Induced, Cancer
- Trial name
- NCT04294550
- Testing
- Naloxegol
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Fondazione ANT Franco Pannuti ETS
Constipation, Critical Illness
Constipation Bundle/Protocol and the Effect of Adherence in the Incidence of Constipation in Critically Ill Patients
Gastrointestinal abnormalities are present in more than 80% of critical patients, and their management has taken an important importance in intensive care unit (ICU), since it can largely determine the clinical outcome, costs and…
- Conditions
- Constipation, Critical Illness, Constipation Drug Induced
- Trial name
- motility (NCT04462211)
- Testing
- Implementation of management pharmacological protocol of constipation, Implementation of bundle of prevention and non-pharmacological management
- Where
- Chile
- Volunteers
- 66 people
- Sponsor
- University of Chile
Opioid-induced Bowel Dysfunction, Constipation Drug Induced
The Efficacy of Acupressure in Managing Opioid-induced Constipation
In a randomized controlled study to evaluate the effect of acupressure application on opioid-related constipation, the Patient Identification Form, Defecation Diary, Visual Analog Scale and Constipation Quality of Life Scale will…
- Trial name
- NCT04876508
- Testing
- Accupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Constipation Drug Induced
Effect of Naloxegol on Gastric, Small Bowel, and Colonic Transit in Healthy Subjects
This research study was being done to study the effect of codeine and Naloxegol for 3 days compared to placebo on the movement of food through the colon of healthy individuals.
- Trial name
- NCT02737059
- Testing
- Naloxegol, Codeine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Michael Camilleri
Colon Cancer, Colon Diverticulosis
Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery
The General Objective of this study is to investigate the cost and efficacy of treating patients undergoing colorectal surgical resections with an opioid limited pain control regimen as part of an Enhanced Recovery After Surgery…
- Conditions
- Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis
- Trial name
- NCT02958566
- Testing
- Acetaminophen, Gabapentin, Orphenadrine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Illinois College of Medicine at Peoria
Drug Induced Constipation
Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118
Study in healthy volunteers to investigate the effects of Quinidine on the Pharmacokinetics of NKTR-118
- Trial name
- NCT01533155
- Testing
- Nektar 118, Quinidine, Morphine
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Drug Induced Constipation
Study in Healthy Volunteers to Investigate the Effects of Rifampin on the Pharmacokinetics of NKTR-118
Study in healthy volunteers to investigate the effects of Rifampin on the Pharmacokinetics of NKTR-118.
- Trial name
- NCT01533870
- Testing
- NKTR-118, Rifampin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Drug Induced Constipation
Study in Healthy Volunteers to Investigate the Effects of Diltiazem on the Pharmacokinetics of Naloxegol
Study in healthy volunteers to investigate the effects of Diltiazem on the Pharmacokinetics of naloxegol.
- Trial name
- NCT01594619
- Testing
- Naloxegol, Diltiazem XR
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- AstraZeneca