Clinical trials: Constitutional Leanness
Constitutional Thinness
Energy Expenditure and Neuromuscular Function in Young Adult Women With a Naturally Thin Build (LeanErgy)
People with a low BMI (<17.5) are most often considered to have anorexia nervosa (AN). However, recent literature suggests that there is a category of individuals with the same low BMI who do not meet the diagnostic criteria for…
- Trial name
- LeanErgy (NCT07233109)
- Testing
- Evaluation of the maximum oxidation point of lipids, Evaluation of the energy cost of walking, Neuro-muscular assessments
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Centre Hospitalier Emile Roux
Healthy Normal Weight Women, Constitutionally Lean Women
Management of Constitutional Thinness Through an Adapted Physical Activity Program, Whether or Not Associated With Food Supplementation. Interventional Study Compared to Matched Controls: NUTRILEAN + Study
The main aim of the present study is to compare the effect of a 12-week physical activity program on body weight gain and body composition changes between normal weight and constitutionally lean individuals.
- Trial name
- NUTRILEAN + (NCT04749706)
- Testing
- Physical training alone, physical training + protein intake
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Anorexia Nervosa, Constitutional Leanness
Energy Intake, Exercise and Constitutional Leanness
The aim of this study will be to identify the physical and dietary profile of adult women presenting constitutional leanness (CL), comparatively with normal-weight peers and BMI-matched women with anorexia nervosa.
- Trial name
- Nutrilean (NCT03981432)
- Testing
- REST-Fixed, REST-AdLib, EX-AdLib
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Thinness, Leanness
Genome Study in Constitutional Thinness
Constitutional thinness (CT) is a recently defined entity as a differential diagnosis of anorexia nervosa (AN), considered to be the most frequent cause of low body mass index (BMI) in young women.
- Trial name
- GENOSCANN (NCT02525328)
- Testing
- blood or saliva specimen
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Lipid Overnutrition, Constitutional Thinness
Adaptation of Lipid and Energy Metabolism During a Lipid Overnutrition in Constitutional Thinness
For a given food intake, fat and energy metabolism in adipose tissue and muscle adapt to nutrient intakes. This adaptation to nutrition may be impaired in susceptible individuals or in obese patients by promoting weight gain…
- Trial name
- Surnutrition (NCT01224561)
- Testing
- Lipid overnutrition
- Where
- 3 sites in France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Osteoporosis, Bone Loss
Bone Microarchitectural Database Constitution From HR-pQCT Device in Clinical Situation Potentially Associated With Bone Loss
Bone fracture occurrence is associated with an increasing of morbidity and mortality. Some factors of fracture occurrence have been highlighted.
- Trial name
- DMPOs (NCT02532439)
- Testing
- HR-pQCT, DEXA, pQCT
- Where
- France
- Volunteers
- 287 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Individuals With Constitutional Thinness
Clinical Trial in Constitutional Thinness
The purpose of this study is to evaluate the molecular differences between a group of Constitutionally Thin (CT) subjects and a group of controls.
- Trial name
- NCT02004821
- Testing
- Renutryl® Booster, an oral nutritional supplement in a 300 ml bottle (600 kcal, 30 g protein, 72 g carbohydrate, 21 g fat). One bottle per day during 14 days.
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Constitutional Thinness
Effect of an Intervention Program of Adapted Physical Activity Combined With Compensatory Nutrition in Patients With Constitutional Thinness
Constitutional Thinness (CT) is a form of stable thinness without malnutrition but with resistance to weight gain, affecting approximately 1% of the general population.
- Trial name
- ANIMATION (NCT06894043)
- Testing
- Adapted Physical Activity (APA), Compensatory Nutrition (NC)
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Anorexia Nervosa, Eating Disorder
Study of the Microbiological Profile of Stool in Patients With Anorexia Nervosa
Anorexia nervosa is an eating disorder whose symptomatology induces a modification of the intestinal microbiota. To date, studies have shown variable profiles without linking them to metabolic and neuropsychological energy…
- Trial name
- ANOSTOOL (NCT03736642)
- Testing
- blood sampling, stool sampling, urine sampling
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne