Clinical trials: Consumption, Tobacco
Alcohol Use Disorder, Hiv
Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2
This study seeks to determine the feasibility, acceptability, and preliminary efficacy of an intervention consisting of off-label use of a medication with strong efficacy data for alcohol use disorder (AUD) with medical…
- Conditions
- Alcohol Use Disorder, Hiv, Tobacco Use Disorder
- Trial name
- HARP (NCT06006143)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Smoking Cessation
Behavioral and Enhanced Perinatal Intervention for Cessation (B-EPIC): Reducing Tobacco Use Among Opioid Addicted Women
This study tests an intervention for tobacco cessation (named B-EPIC) in an established community medication assisted treatment (MAT) clinic for pregnant and postpartum women with opioid dependence.
- Trial name
- B-EPIC (NCT03796208)
- Testing
- Behavioral and Enhanced Perinatal Intervention for Cessation (B-EPIC), Treatment As Usual
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- Kristin Ashford
Chronic Pain, Smoking, Cigarette
Low Nicotine Cigarettes, Smoking, and Chronic Pain
The purpose of this study is to evaluate the effects of switching to very low nicotine content (VLNC) cigarettes versus normal nicotine content (NNC) cigarettes on experiences with craving, withdrawal, and pain among individuals…
- Trial name
- VLNCPain (NCT05032755)
- Testing
- SPECTRUM NRC 102/103 investigational cigarettes, SPECTRUM NRC 600/601 investigational cigarettes
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Nicotine Addiction
Investigation of Cycloserine as a Smoking Cessation Treatment
Psychosocial treatments for drug abuse benefit some patients (Rawson et al 2004), but there is an urgent need for new treatment approaches that can improve treatment outcomes.
- Trial name
- NCT01062932
- Testing
- Cycloserine
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Baylor College of Medicine
Tobacco Use, Smoking Cessation
The Effect of Motivational Interviewing on Smoking Behavior Among Nursing Students
Smoking is one of the leading preventable public health problems worldwide, particularly among young adults who are at increased risk of nicotine dependence.
- Trial name
- NCT07758998
- Testing
- Transtheoretical Model-Based Motivational Interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people
- Sponsor
- Meral Feratoğlu Research
ADHD
Prevention of Cigarette Smoking in Attention Deficit Hyperactivity Disorder (ADHD) Youth With Concerta
This study will consist of a six-week open-label treatment period with an extended duration methylphenidate (OROS MPH) followed by subsequent monthly visits for 24 months in a large sample of youths aged 12-17 who meet Diagnostic…
- Trial name
- NCT00181714
- Testing
- methylphenidate HCl (Concerta)
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Massachusetts General Hospital
Nicotine Dependence, Nicotine Addiction
Effectiveness of N-Acetylcysteine (NAC) in Motivational Enhancement Therapy for Nicotine Addiction
The goal of this clinical trial is to determine the effectiveness of the combination of n-acetylcysteine and motivational enhancement therapy on laboratory improvement in the form of changes in blood nicotine, radiological…
- Trial name
- NCT05903014
- Testing
- n-acetylcysteine, Motivational Enhancement Therapy
- Where
- Indonesia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Smoking, Tobacco Use
BAT3221032: A Study to Evaluate the Effects of Switching From Cigarette Smoking to Using One of Five Variants of a Heated Tobacco Product on Biomarkers of Exposure and Biomarkers of Potential Harm in Healthy Subjects
This is a randomized, controlled, multi-center, open-label, 8-cohort parallel group study to assess changes in select biomarkers of exposure (BoE) and biomarkers of potential harm (BoPH) in generally healthy smokers switching to…
- Conditions
- Smoking, Tobacco Use, Tobacco Smoking
- Trial name
- NCT05142436
- Testing
- Product A: Non-Combusted Cigarette Variant 42001402 and product use Mode B, Product B: Non-Combusted Cigarette Variant 42001399 and product use Mode B, Product C: Non-Combusted Cigarette Variant 42001401 and product use Mode B
- Where
- 18 sites in United States
- Volunteers
- 806 people, healthy volunteers welcome
- Sponsor
- British American Tobacco (Investments) Limited
Smoking, Tobacco Smoking
Effect of Packaging on Smoking Perceptions and Behavior
The investigators are addressing two critical areas identified by the FDA: the impact of cigarette packaging and labeling on consumer perceptions and on smoking behavior; and the effectiveness of graphic warning labels on…
- Trial name
- CASA (NCT02676193)
- Testing
- Effect of Packaging on Smoking Perceptions and Behavior
- Where
- United States
- Volunteers
- 359 people
- Sponsor
- University of California, San Diego
Tobacco Smoking
Developing Genetic Education for Smoking Cessation
This study will test the effects of an educational program about genetics and smoking on smokers' thoughts, feelings, and behaviors before and after participating in smoking cessation treatment.
- Trial name
- NCT01186016
- Testing
- Genetic Education Session, Nutrition Education Session
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Tobacco Use Disorder
Effects of Nicotine Replacement and Repeated Cue Exposure on Cigarette Craving
The purpose of this study is to determine whether Cue Extinction Training will reduce relapse rates in cigarette smokers using the patch to quit.
- Trial name
- NCT01329614
- Testing
- Cue Extinction Training, Nicotine Replacement Therapy, Cue Extinction Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Columbia University
Nicotine Dependence
The Influence of Electronic (ECIG) Heater Resistance on ECIG Acute Effects
The purpose of this study is to measure the individual and combined influence of electronic cigarette (ECIG) heating element resistance and liquid nicotine concentration on ECIG acute effects.
- Trial name
- NCT03496116
- Testing
- ECIG Session
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Tobacco Use Disorder
A Pilot Study of the Neural Correlates of Treatment Effect on Nicotine Craving
The purpose of this study is to gather pilot data to determine feasibility of and guide the development of a larger clinical trial investigating the effects of topiramate as an adjunct to nicotine replacement therapy and…
- Trial name
- NCT00208858
- Testing
- Topiramate
- Where
- United States
- Sponsor
- Emory University
Anxiety Disorders, Anxiety
Personalized Feedback for Smokers With Elevated Anxiety Sensitivity
This project will develop and refine a computer-delivered integrated Personalized Feedback Intervention (PFI) that directly addresses smoking and anxiety sensitivity (AS).
- Conditions
- Anxiety Disorders, Anxiety, Tobacco Dependence, Smoking, Cigarette
- Trial name
- NCT03382093
- Testing
- Personalized Feedback Intervention, Smoking Information Control
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Houston
Smokeless Tobacco Cessation
Nicotine Lozenges and Assisted Self-help for Smokeless Tobacco Cessation
This research study will determine if using a combination of 4-mg nicotine lozenges, self-help materials, and/or telephone tobacco cessation counseling will help smokeless tobacco users stop using tobacco.
- Trial name
- LASH (NCT01341938)
- Testing
- Commit® nicotine lozenges (4 mg) & self-help materials, Commit® nicotine lozenges (4 mg) & phone counseling & self-help materials, Phone counseling & self-help materials
- Where
- United States
- Volunteers
- 1,067 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Cigarette Smoking
Effects of Deep Breathing Exercise on Pulmonary Function, Perceived Stress and Physical Fitness Among Healthy Smokers
Effects of deep breathing exercise on pulmonary function, perceived stress and physical fitness among healthy smokers.
- Trial name
- NCT06032793
- Testing
- Breathing exercises
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cigarette Smoking
Financial Incentives for Smoking Cessation Among Mothers
Investigators will examine whether adding financial incentives and nicotine replacement dual therapy to current best practices for smoking cessation (i.e.
- Trial name
- NCT05740098
- Testing
- Best Practices, Financial Incentives, Nicotine Replacement Therapy
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- University of Vermont
Smoking
Smartphone Application for Smoking Cessation
The purpose of this study is to test the effectiveness of a smartphone application for smoking cessation in smokers ages 18 to 65 years.
- Trial name
- NCT02134509
- Testing
- Experimental App, Active Comparator App
- Where
- United States
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking Cessation, Tobacco Use Cessation
Brief Advice, Nicotine Replacement Therapy Sampling and Active Referral (BANSAR) for Smoking Fathers
This study aims to evaluate the effects of a combined "cocktail", cessation intervention of brief advice, nicotine replacement therapy sampling and active referral (BANSAR) for smoking expectant fathers on smoking cessation…
- Trial name
- BANSAR (NCT03671707)
- Testing
- Brief AWARD advice, Nicotine replacement therapy sampling, Active referral
- Where
- Hong Kong
- Volunteers
- 1,053 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cigarette Smoking, Methadone Maintenance
Pilot Study of Nicotine Nasal Spray and Varenicline on Smoking in Methadone-Maintained Patients
The objective is to provide a preliminary test of the ability of two pharmacological treatments, the nicotine nasal spray and varenicline, relative to placebos, to reduce smoking during the 4 hours following methadone dosing.
- Trial name
- NCT02147132
- Testing
- Nicotine Nasal Spray, Varenicline
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Cincinnati
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