Clinical trials: Contact Lens Care
Contact Lens Care
Evaluation of an Investigational Multi-Purpose Disinfecting Solution for the Care of Silicone Hydrogel Soft Contact Lenses
The objective of the study was to clinically evaluate the safety and effectiveness of a new multi-purpose disinfecting solution in patients wearing silicone hydrogel soft contact lenses.
- Trial name
- NCT00382902
- Testing
- OptiFree Multi-Purpose Disinfecting Solution
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Healthy
Clinical Performance of All-in-One Light Multi-purpose for Silicone Hydrogel Contact Lenses
A clinical trial was conducted to assess the safety and acceptability of the Sauflon Multipurpose Solution when used with four different silicone hydrogel contact lens brands and one conventional hydrogel control lens was…
- Trial name
- NCT01392937
- Testing
- All-in-One Light multipurpose, Aquify care
- Where
- United Kingdom
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Sauflon Pharmaceuticals Ltd
Myopia, Hyperopia
One-month Clinical Evaluation of Oté Sensation Multi-Purpose Solution Care System
The purpose of this study is to evaluate the clinical performance of the contact lens care product Oté Sensation in a representative population of soft contact lens wearers.
- Trial name
- NCT03278223
- Testing
- Test solution, Control solution
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- OTE North America
Contact Lens Care
Evaluation of an Investigational Multi-Purpose Disinfecting Solution for the Care of Soft Contact Lenses in Symptomatic Patients
The objective of the study was to clinically evaluate the safety and effectiveness of a new multi-purpose disinfecting solution for soft contact lenses in patients who experience discomfort with their contact lenses.
- Trial name
- NCT00382603
- Testing
- OptiFree Multi-Purpose Disinfecting Solution
- Where
- United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens-induced Corneal Fluorescein Staining
Corneal Staining and Physiological Compromise After Eight Hours of Soft Contact Lens Wear
The purpose of this study is to assess corneal staining and to measure the relative corneal epithelial "barrier" function (the degree to which the cornea can prevent penetration of colored sodium fluorescein dye into the eye)…
- Trial name
- NCT01015768
- Testing
- ReNu Multiplus multipurpose disinfecting solution, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Adverse Reaction to Contact Lens Solution
The Clinical and Subjective Performance of Three Different MPDS With Silicon Hydrogel Lenses
The purpose of the clinical investigation is to assess the clinical and subjective performance of three novel multipurpose disinfecting solutions (MPDS) in daily wear with two silicone hydrogel contact lenses (Lotrafilcon B and…
- Trial name
- NCT01665612
- Testing
- Contact lens care solution
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Finnsusp Ltd.
Contact Lens Solution Toxicity
The Physiological Consequence of Silicone-hydrogel Care-solution Bio-incompatibility
The purpose of this study is to more objectively evaluate potential lens-material/care solution bio-incompatibilities. We will do this by measuring corneal staining and the amount of fluorescein dye diffusion into the eye.
- Trial name
- NCT00829751
- Testing
- PureVision lenses soaked in ReNu Multiplus, PureVision lenses soaked in OptiFree RePlenish
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Corneal Epithelial Disruption, Corneal Staining
Evaluation of Corneal Staining With Various Contact Lens/Solution Combinations
The purpose of this study is to quantify the amount of corneal staining observed with various marketed contact lens/multipurpose solution combinations.
- Trial name
- NCT00381446
- Testing
- Marketed contact lens care products
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Andrasko, Gary, OD, LLC
Corneal Staining
Assessment of Tear Film-Based Proteins Associated With Care Solution Induced Corneal Staining
The purpose of this study was to investigate the association of inflammatory mediators found in the tear film during the development and following the induction of contact lens solution-induced corneal staining.
- Trial name
- NCT01100424
- Testing
- Opti-Free RepleniSH, ReNu MultiPlus, Balafilcon A
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Myopia, Refractive Error
Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface
The purpose of this study is to utilize in-vivo confocal microscopy to describe differences in corneal epithelial immune status across three lens care regimens in new contact lens wearers.
- Trial name
- NCT01250925
- Testing
- ReNu MultiPlus® MultiPurpose Solution, OPTI-FREE® RepleniSH®, Clear Care®
- Where
- 2 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Myopia
Study Intended to Evaluate the Safety and Effectiveness of a Johnson & Johnson Vision Care Inc, (JJVCI) Contact Lens for Use on an Extended-wear Basis for up to 7 Days (6 Nights).
Study in the US intended to evaluate the safety and effectiveness of a Johnson \& Johnson Vision Care Inc, (JJVCI) contact lens for use on an extended-wear basis for up to 7 days (6 nights).
- Trial name
- NCT00241280
- Testing
- etafilcon A, galyfilcon A
- Where
- 25 sites in United States
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Healthy Contact Lens Wearers
Safety and Efficacy of an Investigational Multi-Purpose Disinfecting Solution
The purpose of this study is to determine if Alcon MPDS is safe and effective for silicone hydrogel and soft hydrogel contact lens wearers.
- Trial name
- NCT01341977
- Testing
- Alcon MPDS, ReNu Fresh MPS
- Where
- United States
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens Care
Corneal Barrier Function With Multi-Purpose Solutions
The purpose of this study is to evaluate the effect on epithelial barrier function of three emarketed multi-purpose solution applied to the human eye with hydrogel lenses as during normal regimen use.
- Trial name
- NCT00407238
- Testing
- Multi-purpose solutions (polyquaternium-1 and PHMB)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Contact Lens Care
Effect of Multi-Purpose Solutions on Ex-Vivo Wetting Angles
To clinically evaluate the effect of a new multi-purpose disinfecting solution compared to a marketed multi-purpose solution on wettability of soft contact lenses worn for 30 days.
- Trial name
- NCT00383201
- Testing
- OptiFree Multi-Purpose Disinfecting Solution
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens Care
Evaluation of an Investigational Multi-Purpose Disinfecting Solution for Care of Soft Contact Lenses
The objective of the study was to clinically evaluate the safety and effectiveness of a new multi-purpose disinfecting solution for soft contact lenses.
- Trial name
- NCT00382681
- Testing
- FID 107027 Multi-Purpose Disinfecting Solution, ReNu MultiPlus Multi-Purpose Solution No Rub Formula
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Glaucoma
Smart Soft Contact Lenses for Monitoring Glaucoma
This study is exploring the effectiveness and safety of soft contact lenses with embedded sensors, called smart contact lenses. Smart contact lenses are used to measure the pressure inside the eye.
- Trial name
- NCT07224542
- Testing
- Bare Contact Lens, Experimental Smart Contact Lens, Commercially available smart contact lens
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Indiana University
Myopia
A Clinical Evaluation of Two Contact Lenses Used With Three Care Systems
The objective of the study was to compare the clinical performance of the two contact lenses when used in combination with three care systems.
- Trial name
- NCT04195581
- Testing
- comfilcon A, fanfilcon A
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Error
Evaluation of a Johnson & Johnson Vision Care Investigational Contact Lens Compared to a Marketed Monthly Replacement Contact Lens
Randomized, double-masked, controlled, 2-arm parallel group, multi-site, 3-month dispensing study of Johnson \& Johnson Vision Care, Inc.
- Trial name
- NCT02515994
- Testing
- senofilcon C, comfilcon A
- Where
- 10 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.