Clinical trials: Contact Lens Comfort
Contact Lenses, Presbyopia
Clinical Performance of Verofilcon A Toric Contact Lenses
The goal of this clinical trial is to [primary purpose: is to determine if Total30 Multi focal toric conntact lensesare comfortable and the willigness for those who have previously worn reusable toric contact lenses are willing…
- Trial name
- NCT07586982
- Testing
- Total 30 multi foric contact lenses
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Corneal Staining
Short-Term Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions
An investigational multi-purpose solution (MPS)was clinically evaluated against Biotrue MPS at specific time points over the course of four days. The study was conducted with PureVision lenses.
- Trial name
- NCT01240122
- Testing
- Biotrue MPS, Investigational MPS
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Contact Lens Complication
A Clinical Study Comparing the Comfort of Three Commercially Available Contact Lenses
The purpose of this study is to compare the comfort of three commercially available contact lenses.
- Trial name
- NCT02298400
- Testing
- Acuvue® Oasys® Lenses (senofilcon A), 30-Day Bausch + Lomb PureVision (balafilcon A), Clariti® 1-Day (Somofilcon A)
- Where
- United States
- Sponsor
- ORA, Inc.
Myopia, Hyperopia
Evaluation of the Effectiveness of Two Marketed Multi-Purpose Solutions for Silicone Hydrogel Contact Lenses - Study 2
The purpose of this study was to evaluate the performance of Opti-Free® PureMoist® Multi-purpose Disinfecting Solution (MPDS) compared to AMO RevitaLens OcuTec® MPDS (US brand name)/COMPLETE RevitaLens (Europe brand name) in…
- Conditions
- Myopia, Hyperopia, Contact Lens Comfort
- Trial name
- NCT01684046
- Testing
- Opti-Free® PureMoist® MPDS, RevitaLens MPDS, Habitual Contact Lenses
- Volunteers
- 196 people
- Sponsor
- Alcon Research
Myopia, Refractive Error
Multi-Center Clinical Evaluation of Two Daily Disposable Contact Lenses
The purpose of this study is to compare the subjective performance of two daily disposable contact lenses with respect to comfort and handling.
- Trial name
- NCT01898260
- Testing
- Ultrafilcon B contact lens, Stenfilcon A contact lens
- Where
- United Kingdom
- Volunteers
- 89 people
- Sponsor
- Alcon Research
Contact Lens Base Curve (BC) Fit and Comfort
Evaluation of 8.5 vs 9.0 Base Curve for 1-DAY ACUVUE(r) TruEye(r) Brand Contact Lenses
The objective of this study is to determine if corneal diameter and keratometry readings correlate to subjective comfort and lens fitting characteristics.
- Trial name
- NCT02537522
- Testing
- Contact Lenses with 8.5 BC, Contact Lenses with 9.0 BC
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Corneal Staining
Comfort Evaluation of a New MPS vs. Replenish in Contact Lens Patients
To compare corneal staining after contact lens instillation with a new MPS vs. RepleniSH
- Trial name
- NCT00518700
- Testing
- new MPS, RepleniSH
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Innovative Medical
Dry Eye, Contact Lens Complication
Dailies Total 1 Sphere Contact Lenses
CL discomfort is a complex phenomenon that has been defined by the Tear Film and Ocular Surface Society in their seminal report on contact lens (CL) discomfort as a condition that results in "episodic or persistent adverse ocular…
- Trial name
- NCT05239494
- Testing
- DT1 Sphere Contact Lenses
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Contact Lens Comfort and Successful Refitting, Presbyopia
Refitting Satisfied INFUSE One-Day Multifocal Wearers to DAILIES TOTAL1 Multifocal Contact Lenses
The purpose of this study is to determine the comfort and vision of DAILIES TOTAL1 Multifocal contact lenses in a population of satisfied INFUSE One-Day Multifocal contact lens wearers
- Trial name
- INFUSETODT1 (NCT07638943)
- Testing
- DAILIES TOTAL1 Multifocal (delefilcon A)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gordon Schanzlin New Vision
Contact Lens Related Dry Eye
The Impact of Hypo-osmolar Drops on Contact Lens Comfort
This pilot study will investigate the impact of sterile saline drops that are formulated at hypo-osmolar levels on CL comfort in comparison to an iso-osmolar drop, in a group of symptomatic CL wearers.
- Trial name
- SAFFRON (NCT03050125)
- Testing
- Hypo-osmolar drop 1, Hypo-osmolar drop 2, Iso-osmolar drop
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre for Contact Lens Research
Refractive Error, Myopia
Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
The purpose of this study was to compare lens comfort on Day 30 for Air Optix® lenses cared for with OPTI-FREE® PureMoist® (OFPM) Multi Purpose Disinfecting Solution (MPDS) compared to Acuvue® Oasys® lenses cared for with…
- Conditions
- Refractive Error, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01809197
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE PureMoist Multi-Purpose Disinfecting Solution (MPDS)
- Volunteers
- 387 people
- Sponsor
- Alcon Research
Dry Eye, Contact Lens Complication
Total30 For Contact Lens Dropouts
Contact lens (CL) discomfort is a complex phenomenon that has been defined by the Tear Film and Ocular Surface Society (TFOS) in their seminal report on CL discomfort as a condition that results in "episodic or persistent adverse…
- Conditions
- Dry Eye, Contact Lens Complication, Contact Lenses
- Trial name
- T30DO (NCT06967298)
- Testing
- T30 Contact lenses
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Adverse Reaction to Contact Lens Solution
The Clinical and Subjective Performance of Three Different MPDS With Silicon Hydrogel Lenses
The purpose of the clinical investigation is to assess the clinical and subjective performance of three novel multipurpose disinfecting solutions (MPDS) in daily wear with two silicone hydrogel contact lenses (Lotrafilcon B and…
- Trial name
- NCT01665612
- Testing
- Contact lens care solution
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Finnsusp Ltd.
Contact Lens Complication, Astigmatism
Total30 for Astigmatism Contact Lenses
Determine if Total30 for Astigmatism contact lenses (CLs) provide a comfortable wearing experience all day. CL discomfort affects most CL wearers with discomfort consistently topping the reasons why established CL wearers drop…
- Conditions
- Contact Lens Complication, Astigmatism, Refractive Errors
- Trial name
- NCT06052046
- Testing
- TOTAL30 for Astigmatism Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Contact Lens Comfort
Acuvue Oaysis Contact Lens Wearers Being Refit Into P7 Contact Lenses
Determine the likelihood of successfully refitting a satisfied AOA CL wearers into P7A CLs
- Trial name
- NCT06955403
- Testing
- Precision 7 contact lenses
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Dry Eye, Dry Eye Syndromes
Assessment of Tear Production, Corneal Staining, and Comfort Level Wearing Different Types of Contact Lenses
This research assesses the tear performance of five distinct types of soft contact lenses commonly found in the market. The study involves contact lens participants, all of whom are students enrolled at UKM.
- Conditions
- Dry Eye, Dry Eye Syndromes, Contact Lens-induced Corneal Fluorescein Staining
- Trial name
- NCT06351410
- Testing
- Eye Wearing Contact Lens
- Where
- Malaysia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Myopia, Astigmatism
Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers
The purpose of this study was to assess the comfort of OPTI-FREE RepleniSH in soft contact lens wearers.
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01211535
- Testing
- OPTI-FREE RepleniSH multipurpose solution, ReNu Biotrue multipurpose solution, Silicone hydrogel contact lenses
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Alcon Research
Meibomian Gland Dysfunction
Contact Lens Comfort Relative to Meibomian Gland Status
This trial aims to establish a correlation between patient reported comfort while using soft contact lenses and meibomian gland dysfunction (MGD).
- Trial name
- NCT01819194
- Testing
- senofilcon A
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lens Comfort and Successful Refitting
How Does DT1 Sphere Perform in Current and Successful Acuvue MAX Wearers?
The goal of this prospective study is to to understand if satisfied MAX Contact lens (CL)wearers can be successfully refit into Dailies total 1 (DT1) CL in healthy MAX CL wearers between the ages of 18-40.
- Trial name
- NCT06847230
- Testing
- Dailies total 1 contact lenses
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Contact Lens Wear
Subjective Comfort With Multipurpose and Hydrogen Peroxide Lens Care Solutions in Soft Contact Lens Wearers
The purpose of this study was to assess comfort in soft contact lens wearers.
- Trial name
- NCT01164865
- Testing
- OPTI-FREE RepleniSH multipurpose disinfecting solution, Clear Care contact lens care system, Contact lenses
- Volunteers
- 78 people
- Sponsor
- Alcon Research