Clinical trials: Contact Lens Wear
Contact Lens
Evaluation of Wear Experience With a Water Surface Daily Disposable Contact Lens
The purpose of this study is to assess the wear experience of existing wearers of a monthly replacement contact lens after they have been fit with a daily disposable contact lens that has water surface treatment.
- Trial name
- NCT05102383
- Testing
- Comfilcon A Toric contact lenses, Verofilcon A for Astigmatism Daily Disposable contact lenses
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Astigmatism Bilateral
Evaluation of Wear Experience With a Weekly Replacement Soft Contact Lens in Neophyte Lens Wearers With Astigmatism
This open-label study is of adults with astigmatism who have never worn contact lenses. Subjects will be fit into a one week planned-replacement contact lenses and will wear lenses for approximately 3 weeks.
- Trial name
- NCT06751225
- Testing
- One week replacement soft contact lenses
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
Performance and Safety of Silicone Hydrogel Soft Contact Lenses
To demonstrate substantial equivalence of the new Silicone Hydrogel Soft Contact Lenses(SHSCL) to the commercially available ACUVUE® VITA™ contact lens
- Trial name
- NCT04226560
- Testing
- 41% Silicone Hydrogel Soft Contact Lenses(SHSCL), ACUVUE® VITA™ (senofilcon C) Brand (Soft) Contact Lens, Contact Lens Care Product
- Where
- Taiwan
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- ApexLens Co., Ltd.
Ametropia
Safety and Acceptability of Using a Rewetting Drop With Contact Lens Wear
Testing the Safety and Acceptability of Using a Rewetting Drop with Contact Lenses
- Trial name
- NCT00691197
- Testing
- Carboxymethylcellulose sodium and Glycerin, Carboxymethylcellulose sodium
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Allergan
Contact Lenses, Extended-Wear
A Comparison of 12 Month Daily Wear of Two Novel O2 Permeable Silicone Hydrogel CLs (HOP/SiH) and A Control, Standard O2 Lens
The purpose of this research is to compare the on-eye performance of 12 month daily wear versus 6-night extended wear and 30-night extended wear of novel hyper-oxygen permeable contact lenses by studying its effects on human…
- Trial name
- NCT00344643
- Testing
- Silicone Hydrogel Soft Contact Lenses
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Dry Eye Syndromes
The Effect of Punctal Plugs on Tear Volume and Osmolality
The purpose of this study is to evaluate the role of tear volume in discomfort and dryness sensations during contact lens wear, and the possible influence on osmolality and ocular surface sensitivity.
- Trial name
- NCT00372034
- Testing
- Temporary Collagen Inserts
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of New South Wales
Contact Lens
Wear Experience With Daily Contact Lenses Over a Long Day
This study is evaluating the wear experience of a daily contact lens after 10, 12, 14, and 16 hours of lens wear.
- Trial name
- NCT04535310
- Testing
- Precision1® Daily Disposable Contact Lens
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
LSH Silicone Hydrogel Soft Hydrophilic Contact Lens for Daily Wear
This study is to evaluate the performance of the LSH (mangofilcon A) silicone hydrogel soft contact lenses when used as a daily wear contact lens for the correction of myopia.
- Trial name
- NCT01735045
- Testing
- Lagado LSH (mangofilcon A) Soft (hydrophilic) Contact Lens, Benz 3GX (hioxifilcon B) Soft (hydrophilic) Contact Lens
- Where
- 5 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Szabocsik and Associates, Inc.
Myopia
A Two-Week Crossover Dispensing Evaluation Of Orion Daily Wear Soft Contact Lens
The primary objective of the study is to evaluate the clinical performance of test lens (Orion) in comparison with control lens (Gemini) over a period of two weeks of wear.
- Trial name
- NCT04585646
- Testing
- Orion daily disposable contact lens, Gemini daily disposable contact lens
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Ametropia
Study of Soft Contact Lens Use With 7 Day Extended Wear
To compare the safety and efficacy of the CVI silicone-hydrogel lens worn on an extended wear basis for a period of up to 7 days and 6 nights with the Acuvue 2 soft contact lenses.
- Trial name
- NCT00597467
- Testing
- VISA (comfilcon A) Silicone Hydrogel Soft contact lens, Acuvue 2 Soft Contact Lens
- Where
- 23 sites in United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Corneal Epithelial Permeability
Daily Irrigation With Silicone Hydrogel Contact Lens Continuous Wear
This study sought to determine whether daily irrigation with sterile saline solution during silicone hydrogel (SiH) contact lens continuous wear (CW) could improve ocular surface integrity and reduce the risk of adverse events.
- Trial name
- EW23 (NCT03139812)
- Testing
- Daily irrigation, 30-day SiH CW
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Contact Lens Wear
An Evaluation of a Marketed Lubricated Eye Drop in Soft Contact Lens Wearers Who Experience Ocular Dryness
Study to evaluate subjective comfort associated with the use of a marketed lubricant eye drop, by subjects reporting ocular dryness and wearing soft contact lenses on a daily disposable replacement schedule.
- Trial name
- NCT01132287
- Testing
- FID 112903
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder)
24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring
The goal of this clinical trial is to learn if a new contact lens device can record patterns in eye pressure for 24 hours in adults with glaucoma and in healthy participants.
- Conditions
- Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder), Ocular Hypertension, Ocular Hypertension (OH)
- Trial name
- NCT06689696
- Testing
- miLens system
- Where
- 3 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Smartlens, Inc.
Myopia
Effects of Contact Lens Wear on Children's Self-Perceptions
The purpose of the study is to determine whether contact lens wear will improve children's self-perceptions more than spectacle wear.
- Trial name
- ACHIEVE (NCT00522288)
- Testing
- Soft contact lenses, Spectacle
- Where
- 5 sites in United States
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Refractive Error
Comparative Study of Two Marketed Spherical Soft Contact Lenses
The purpose of this study is to obtain objective and subjective clinical data to compare the performance of two soft contact lenses.
- Trial name
- NCT01582789
- Testing
- enfilcon A, senofilcon A
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cornea, Sense Loss; Cornea
Investigation in Corneal Sensation and Contact Lens Wear
The aim is to find out more about how corneal sensory fibres react to different types of stimuli (liquid / tactile / nylon thread) and how this can be consciously perceived by the individual.
- Trial name
- NCT04804592
- Testing
- Tactile Esthesiometer Prototype, Liquid Jet Esthesiometer Prototype, Cochet Bonnet esthesiometer
- Where
- Switzerland
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Daniela Nosch
Contact Lens
Evaluation of Wear Experience With Daily Contact Lenses
To evaluate the wear experience of current monthly replacement contact lens wearers after they have been fit into a daily disposable contact lens.
- Trial name
- NCT05096156
- Testing
- Precision1® Daily Disposable Contact Lens
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Cornea
Influence of Silicone Hydrogel Contact Lens Neophyte Wear on Corneal Sensitivity
Soft contact lenses can affect the ocular surface and sometimes cause intolerance. The aim of this study is to measure corneal sensitivity using the Swiss Liquid Jet aesthesiometer at baseline, after one and after six weeks, in…
- Trial name
- CSCL (NCT05745220)
- Testing
- Device: silicone hydrogel contact lens
- Where
- Switzerland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Daniela Nosch
Ocular Physiology
Clinical Evaluation of Delefilcon A and Verofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear
This is a bilateral-wear, dispensing, randomized, controlled, double-masked, 2-sequence × 2-period crossover study to evaluate ocular physiology following contact lens wear.
- Trial name
- NCT05502289
- Testing
- TEST LENS, CONTROL LENS
- Where
- 6 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Scleral Contact Lenses
Effect of Ocular Hygiene on Scleral Lens Wear
This is a study to evaluate the performance of Lid Scrubs when added to the daily regimen of scleral lens wear. Lid Scrubs contain surfactants and chemically developed Ringer's solution with microbial attributes.
- Trial name
- NCT03544385
- Testing
- Ringers Solution
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Houston