Clinical trials: Contingency Management
Tobacco Cessation, Tobacco Use
Persistent Poverty Counties Pregnant Women With Medicaid
Although many women initially quit smoking during pregnancy, most will return to smoking by the end of pregnancy or during the first 6 months postpartum.
- Conditions
- Tobacco Cessation, Tobacco Use, Tobacco Smoking, Smoking Cessation Financial Incentives
- Trial name
- NCT05415371
- Testing
- Standard Care + Financial Incentives, Standard Care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Opiate-Replacement Therapy
Automated Prize-based Contingency Management to Increase Counseling Attendance in Opiate-Replacement-Therapy Patients
Background: Treatment outcomes for substance abuse are improved by regular attendance at counseling sessions, and attending at counseling sessions can be futher improved by prize-based incentives.
- Trial name
- NCT01229163
- Testing
- Automated Contingency Management (ACM) software
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
E-Cig Use
Quit Nicotine: E-Cig Cessation Intervention
The purpose of this study is to find out if a new intervention helps teenagers who vape nicotine quit vaping. The program involves two parts: giving rewards (also called contingency management [CM]) and online video counseling…
- Trial name
- NCT04898075
- Testing
- Remote Contingency Management (CM) for nicotine abstinence, Control
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University
Hepatitis C, Chronic
A Trial to Assess the Effect of an Intervention Integrating Contingency Management (Financial Incentives) to Enhance Hepatitis C Treatment Uptake Following Dried Blood Spot Hepatitis C RNA Testing Among People With Recent Injecting Drug Use Attending Needle and Syringe Programs
A pilot two-arm, individual-level, randomised controlled trial to assess the effect of an intervention integrating contingency management (financial incentives) to enhance hepatitis C treatment uptake following dried blood spot…
- Trial name
- AMPLIFY (NCT04428346)
- Testing
- Incentive payment
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
Longitudinal Studies, Prospective Studies
Clinical Time and Temporal Dynamics Study (CLIN-TIME)
TH-CLINICAL-TIME is a prospective, longitudinal observational study evaluating how changes in clinical measurements over time may help researchers better understand patient health trajectories and clinically meaningful outcomes.
- Conditions
- Longitudinal Studies, Prospective Studies, Biomarkers, Predictive Value of Tests
- Trial name
- CLIN-TIME (NCT07812831)
- Testing
- No Study-Assigned Intervention
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Healthy Subjects
Co-Administration Of Fosamprenavir With Methadone: A Drug Interaction Study.
To assess the combined effects of fosamprenavir 700mg BID + ritonavir 100mg BID + standardized dose of methadone, on plasma total and unbound methadone enantiomer pharmacokinetics (PK), opiate pharmacodynamic (PD) measures, and…
- Trial name
- NCT00481182
- Testing
- fosamprenavir + ritonavir + methadone
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Substance Abuse, Cocaine Dependence
Bupropion-Enhanced Contingency Management (CM) for Cocaine Dependence
This project will examine effects of bupropion extended release (XL) at a dose of 300mg/day for cocaine abstinence among persons receiving methadone for the treatment of opioid use disorder.
- Trial name
- NCT02111798
- Testing
- Bupropion XL, Abstinence Initiation, Relapse Prevention
- Where
- 2 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Tobacco Dependence
A Study of Novel Smoking Cessation Interventions in Current and Former Injection Drug Users
Cigarette smoking is very common in current and former injection drug users and is known to cause chronic lung diseases. Quitting smoking is proven to improve the health of people addicted to cigarettes. .
- Trial name
- NCT01334736
- Testing
- Usual care, Lung age, Contingency Management
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Opioid-Related Disorders
Buprenorphine as a Treatment for Individuals Dependent on Analgesic Opioids
Opioids used to treat chronic pain have a high abuse potential. The purpose of this study is to determine the effectiveness of buprenorphine in treating opioid dependent individuals who abuse opioids that are prescribed for…
- Trial name
- NCT00218101
- Testing
- Buprenorphine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Substance Abuse Problem
Web-Based Contingency Management Training for Addictions
Adolescent substance abuse results in significant negative outcomes and extraordinary costs for youths, their families, communities and society (societal costs estimated at over $400 billion annually and greater than costs for…
- Trial name
- CM-TSS (NCT02740881)
- Testing
- Counselor Training Methods
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Sheidow Consulting, Inc.
Cannabis Use, Adolescent Behavior
Pilot Trial of Contingency Management for Long-Term Cannabis Abstinence
This study is a critically important first-of-its-kind investigation of the potential research utility of using contingency management to examine long-term changes in cannabis use with six months of abstinence.
- Trial name
- NCT03786224
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Asthma, Incentives
Financial Incentives to Reduce Pediatric Tobacco Smoke Exposures
Secondhand smoke exposure (SHSe) is one of the most common and potentially modifiable environmental triggers for asthma. Financial incentivization may serve as an effective modality to reduce SHSe among pediatric asthmatics with…
- Conditions
- Asthma, Incentives, Tobacco Smoking
- Trial name
- NCT03099811
- Testing
- Incentive plan, Smoking cessation
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Alcohol Use Disorder (AUD), Nicotine Use Disorder
Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking
Using a randomized controlled trial (RCT), the goal of this study is to evaluate the ability of evidence based behavioral treatment (contingency management: CM) to significantly decrease alcohol use and cigarette smoking among…
- Trial name
- PERRAS (NCT05181891)
- Testing
- Contingency Management, Non-contingent control
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Washington State University
Smoking Cessation
Preliminary Test of Reactive Carrot Incentives in a Practice Quit Environment With Contingency Management Incentives
The primary aim of this study is to pilot test a novel reactive carrot approach for improving individuals' ability to stick to a "practice quit" program in a smoking cessation context.
- Trial name
- NCT05072301
- Testing
- Contingency Management, Control
- Where
- 2 sites in United States, Ukraine
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Yale University
Overweight, Obese
Lose 2 Win A Novel Method to Motivate Weight Loss Maintenance Among College Students
Investigators are conducting a randomized controlled trial with overweight and obese college students on the University of Minnesota campus.
- Trial name
- L2W (NCT02021383)
- Testing
- Bi-weekly in person meetings with a Registered Dietician, Financial incentives for weight loss maintenance
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
COVID-19 Pandemic
Motivation, Syringe Exchange, and COVID-19
People who inject drugs (PWIDs) are highly vulnerable to SARS-CoV-2 infection and to the disease caused by SARS-CoV-2, coronavirus disease 2019 (COVID-19), however, rates of SARS-CoV-2 testing and vaccination uptake -vital to…
- Trial name
- NCT05534061
- Testing
- Connect2Test
- Where
- United States
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Substance-Related Disorders, HIV
Expression of Stress Markers During Meth Treatment (EXPRESS+)
This is a non-randomized behavioral trial that aims to investigate whether changes in inflammatory and type I IFN expression coincide with changes in methamphetamine use and viral load over the course of 12 weeks in HIV-positive…
- Trial name
- EXPRESS+ (NCT05558345)
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Alcohol Use Disorder
Phosphatidylethanol-Based Contingency Management for Housing
The investigators will evaluate the efficacy of contingency management (CM) in reducing alcohol use in individuals experiencing unstable housing but who are currently housed in shelters.
- Trial name
- NCT04038021
- Testing
- Phosphatidylethanol-based Contingency Management, Non-Contingent Control
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Washington State University
Tobacco Prevention and Cessation
Incentive-based Intervention for Smoking Cessation and Prevention in High Schools
The purpose of this study is to design an incentive-based intervention to motivate a tobacco-free lifestyle among high school students and to pilot the intervention in the first academic year in two schools (CT and NY) and…
- Trial name
- Rise Above (NCT01173835)
- Testing
- Incentives for being tobacco free
- Where
- United States
- Volunteers
- 1,651 people, healthy volunteers welcome
- Sponsor
- Yale University
Methamphetamine-dependence, HIV-1-infection
Contingency Management for PrEP Adherence and/or Methamphetamine Use
Use of crystal methamphetamine (MA) leads to changes in sexual risk behavior, adherence to HIV prevention tools, immune response to infection, and tissue inflammation that collectively increase risk for HIV transmission among…
- Trial name
- C-MAX (NCT04563962)
- Testing
- Contingency Management-ART, Contingency Management-Methamphetamine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles