Clinical trials: Contingency Management, open to volunteers
Pregnancy, Substance Use Disorder (SUD)
Substance Use in Pregnancy - Optimizing Retention in Treatment by Maximizing Opportunities for Management
Overdose is a national top-three leading cause of pregnancy-associated death, and maternal substance use disorder (SUD) accounts for an estimated $1.5 billion in healthcare spending each year.
- Trial name
- SUPPORT MOM (NCT07776457)
- Testing
- Contingency Management, Social Drivers of Health Screening
- Where
- United States
- Volunteers
- 245 people
- Sponsor
- Washington University School of Medicine
Type 2 Diabetes, Non Insulin Dependent Diabetes
T2D Intermittent Nonprescription Sensors for Informed Glucose Health Tracking
The goal of this clinical trial is to learn if periodic use of over-the-counter continuous glucose monitoring (CGM) can support glucose management in people with type 2 diabetes not using insulin being treated in primary care…
- Trial name
- T2D INSIGHT (NCT07422831)
- Testing
- Periodic, over-the-counter continuous glucose monitoring
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- University of Colorado, Denver
Alcohol Use Disorder, Alcohol Drinking
Virtual Incentive Treatment for Alcohol
The overall objective of this program of research is to utilize phosphatidylethanol (PEth), a blood-based biomarker that can detect alcohol use for up to 28 days to deliver a feasible telehealth-based 26-week CM intervention.
- Conditions
- Alcohol Use Disorder, Alcohol Drinking, Alcohol Abuse, Alcohol Dependence
- Trial name
- VITA (NCT06265506)
- Testing
- Contingency Management, Computer Based Training for Cognitive Behavioral Therapy for AUD (CBT4CBT)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Washington State University
Smoking Cessation
Contingency Management to Promote Smoking Cessation Study
Adherence to medication and counseling are strong predictors of smoking cessation success. To provide these two components of care, healthcare providers typically provide people who smoke with prescriptions for cessation…
- Trial name
- NCT07685899
- Testing
- Health Rewards, Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Kansas Medical Center
Alcohol Use
The Less is More Study
In this project, the investigators will implement innovations to extend use of Contingency Management (CM) to facilitate alcohol use reduction among people living with HIV (PLWH).
- Trial name
- NCT05153811
- Testing
- Counseling, mHealth
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Florida
Alcohol Use Disorder, Insomnia
Daridorexant for People With Insomnia and Alcohol Use Disorder Study
The goal of this clinical trial is to see if a sleep medication, daridorexant (DTX), can help decrease drinking in people who have alcohol use disorder (AUD) and insomnia.
- Trial name
- DIAS (NCT07701928)
- Testing
- Daridorexant, Brief Counseling, MEMS and Medication Accounting
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- Sterling McPherson
Postpartum Depression (PPD), Alcohol Use
Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms
This study aims to learn about depression and alcohol use in postpartum mothers and whether an intervention based on contingency management and problem-solving therapy (CM-PST) can help reduce these symptoms.
- Conditions
- Postpartum Depression (PPD), Alcohol Use, Contingency Management, Problem Solving Therapy
- Trial name
- MOMS-AD (NCT07485036)
- Testing
- Contingency Management & Problem Solving Therapy, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Illinois Chicago
Alcohol Use Disorder (AUD)
TRIS: Contingency Management App for Alcohol Use Disorder
Alcohol Use Disorder (AUD) is a major public health concern associated with substantial morbidity, mortality, and impaired social and occupational functioning.
- Trial name
- NCT07735585
- Testing
- Remote Contingency Management (CM), Treatment as Usual (TAU)
- Where
- Brazil
- Volunteers
- 130 people
- Sponsor
- University of Sao Paulo General Hospital
Type 2 Diabetes Mellitus, Periodontitis
Integrated Diabetes and Oral Health Care in Oman
Type 2 diabetes mellitus (T2DM) and periodontal (gum) disease are closely related conditions that may negatively affect each other. However, oral health is not routinely integrated into diabetes self-management education.
- Conditions
- Type 2 Diabetes Mellitus, Periodontitis, T2DM, Periodontal Disease
- Trial name
- NCT07809477
- Testing
- Health Belief Model-Based Integrated Diabetes-Oral Health Educational Intervention, Standard Diabetes Education and Routine Care
- Volunteers
- 290 people
- Sponsor
- Oman Ministry of Health
Stimulant Use (Diagnosis)
Implementing Contingency Management for Stimulant Use in Specialty Addiction Treatment Organizations
Stimulants constitute a new and deadly fourth wave of the opioid epidemic. Contingency management is the most effective intervention for stimulant use and is an evidence-based adjunct to medication for opioid use disorder.
- Trial name
- MIMIC2 (NCT05702021)
- Testing
- Science to Service Laboratory
- Where
- 9 sites in United States
- Volunteers
- 76 people
- Sponsor
- Northwestern University
HIV, Methamphetamine Disorders
PrEP Readiness Interventions for Sustained Motivation (PRISM)
This is a hybrid type I randomized controlled trial to test the effectiveness of contingency management (CM) alone versus CM with motivational interviewing (MI) for optimizing entry or re-entry into the HIV prevention or care…
- Trial name
- PRISM (NCT06637436)
- Testing
- Motivational Interviewing (MI), Contingency Management (CM)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Florida International University
Fear of Falling, Balance Changes
Floor-hugging Intervention: Managing Fear of Falling Through Floor Exposure and Developing After-fall Contingency
Fear of falling is a major public health problem and is characterized by a lack of confidence in one's ability to maintain balance and prevent falls.
- Conditions
- Fear of Falling, Balance Changes, Healthy
- Trial name
- Floor-HI (NCT06815809)
- Testing
- Floor-HI (intervention combines floor exposure with floor rise strategies)
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Karlstad University
Ischemic Stroke, Embolic Stroke of Undetermined Source
SENIOR: Stroke Prevention in the Elderly by Patent Foramen Ovale closuRe vs Anticoagulation
Patent foramen ovale (PFO) is an important mechanism of embolic stroke of undetermined source (ESUS). Current guidelines recommend PFO closure for high-risk PFO in patients younger than 60 years, and a recent retrospective cohort…
- Conditions
- Ischemic Stroke, Embolic Stroke of Undetermined Source, Patent Foramen Ovale (PFO), Elderly
- Trial name
- SENIOR (NCT07479147)
- Testing
- PFO closure, Medication
- Where
- 3 sites in Taiwan
- Volunteers
- 400 people
- Sponsor
- Taichung Veterans General Hospital
Stimulant Use Disorder
Smartphone Services for Stimulant Use Disorder
This study is testing two approaches to treating Stimulant Use Disorder, or problems with cocaine, crack, methamphetamine, etc. Stimulant Use Disorder is a national epidemic in the U.S.
- Trial name
- NCT07092059
- Testing
- Smartphone digital therapeutic system
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- DynamiCare Health
HIV, Pre-exposure Prophylaxis
Case Management Dyad
The overall goal of this study is to test whether dyadic and focused case management coupled with contingency management will (1) improve financial wellbeing, (2) improve access to food, (3) increase linkage and retention rates…
- Conditions
- HIV, Pre-exposure Prophylaxis, Case Management, Contingency Management
- Trial name
- CM2 (NCT06162897)
- Testing
- Dyadic Case Management
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Longitudinal Studies, Prospective Studies
Clinical Time and Temporal Dynamics Study (CLIN-TIME)
TH-CLINICAL-TIME is a prospective, longitudinal observational study evaluating how changes in clinical measurements over time may help researchers better understand patient health trajectories and clinically meaningful outcomes.
- Conditions
- Longitudinal Studies, Prospective Studies, Biomarkers, Predictive Value of Tests
- Trial name
- CLIN-TIME (NCT07812831)
- Testing
- No Study-Assigned Intervention
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
HIV, Contingency Management
J-RISE: Relevant Implementation Strategies to Eliminate the Social and Structural Barriers to HIV Services Among Justice-involved Black Men Who Have Sex With Men and Other Key Populations
The goal of this clinical trial is to compare two interventions - Health Navigation and Health Navigation Plus among individuals who have been impacted by the criminal legal system.
- Conditions
- HIV, Contingency Management, Justice Involved Populations, Status Neutral Interventions
- Trial name
- J-RISE (NCT06477588)
- Testing
- Health Navigation, Health Navigation, Employment Navigation plus Contingency Management Intervention
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Hypertension, Vascular Stiffness
Arterial Stiffness and Blood Pressure
Hypertension is a common and treatable disorder that remains the leading preventable cause of heart disease. Blood pressure treatment relies mainly on upper arm blood pressure readings and ignores blood vessel physiology and…
- Conditions
- Hypertension, Vascular Stiffness, Aging
- Trial name
- LOADED-BP (NCT06495710)
- Testing
- Blood pressure treatment algorithm
- Where
- 3 sites in United States
- Volunteers
- 228 people
- Sponsor
- VA Office of Research and Development
HIV Risk
Supporting Health and Empowerment Through Contingency Management and Affect Regulation
The goal of the SHE CARES study is to better understand factors that influence engagement in HIV prevention and substance use services among women who use stimulants in North Carolina.
- Trial name
- SHE CARES (NCT07792161)
- Testing
- urine-based self-test, urine-based clinic test
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Gambling Disorder, Gambling Problem
Contingency Management to Reinforce Attendance to Cognitive Behavioral Treatment for Gambling Disorder
The aim of this study is to conduct a trial to investigate the effectiveness of adding contingency management treatment (CM) to standard care cognitive behavioral therapy (CBT) for the treatment of gambling disorder to increase…
- Trial name
- NCT07016100
- Testing
- Contingency management, Cognitive behavioral therapy/ treatment as usual
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- East Tennessee State University