Clinical trials: Contraceptive Device; Complications
Endometriotic Cyst of Ovary
Letrozole in Preventing Recurrence of Endometrioma Following Laparoscopic Ovarian Cystectomy
Endometriosis is a chronic inflammatory disease that affects approximately 10-15% of women of reproductive age. Symptoms include dysmenorrhoea, chronic pelvic pain, dyspareunia and infertility.
- Trial name
- NCT05487092
- Testing
- Letrozole
- Where
- 5 sites in Hong Kong
- Volunteers
- 194 people
- Sponsor
- The University of Hong Kong
Bacterial Vaginosis, HIV
Effects of Contraceptive Ring on Vaginal Microbiota, HIV Shedding and Local Immunity
The investigators propose to explore the hypothesis-supported by limited data-that a contraceptive vaginal ring (CVR) that is commonly used in the United States, the NuvaRing, will enhance women's genital and reproductive health.
- Trial name
- NCT02445989
- Testing
- NuvaRing
- Where
- Kenya
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Washington
Polycystic Ovary Syndrome (PCOS), Overweight
The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS
Polycystic ovary syndrome (PCOS) is a health problem that affects one in 10 women of childbearing age, which is usually characterized by hormonal imbalance and metabolism problems such as hyperandrogenism and obesity.
- Conditions
- Polycystic Ovary Syndrome (PCOS), Overweight, Obesity
- Trial name
- NCT03151005
- Testing
- Metformin-GLP-1 Receptor Agonist, Metformin-Oral Contraceptive(OC)
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Xinqiao Hospital of Chongqing
Uterine Hemorrhage
Management of Initial Bleeding/Spotting Associated With the Levonorgestrel-releasing Intrauterine System (MIRENA)
The purpose of the study is to investigate if the study drugs (tranexamic acid or mefenamic acid) can control irregular bleeding during the first 3 months of using Mirena.
- Trial name
- NCT01295294
- Testing
- Tranexamic acid, Mefenamic acid, Mirena (Levonorgestrel IUS, BAY86-5028)
- Where
- 12 sites in Denmark, Ireland and 1 more
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Bayer
Menstrual Problem, Quality of Life
Menstrual Wellbeing in Woman Living in Turkey; an Epidemiological Study
Women with endometriosis in our country and around the world face various difficulties during their menstrual periods in reproductive age.
- Trial name
- NCT05442541
- Testing
- not included any interventions(Evaluation of menstrual well-being in women of reproductive age, field survey study)
- Where
- Turkey (Türkiye)
- Volunteers
- 1,829 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Ectopic Pregnancy
Reproductive Health Education, Birth Control and Sexual Quality of Life in Ectopic Pregnancy
Ectopic pregnancy (EP) is defined as the implantation of a fertilized ovum outside the uterine cavity, most commonly in the fallopian tubes.
- Trial name
- NCT07431411
- Testing
- Reproductive Health Counseling and Educational Brochure
- Volunteers
- 102 people
- Sponsor
- Buket Kömürcü
Endometriosis
Comparing the Use of Dienogest and Combined Oral Contraceptive Pills (Microgynon) to Reduce the Risk of Recurrence of Endometriotic Cyst After Conservative Surgery
The purpose of the study is to compare the recurrence of endometriotic cyst in patients taking Dienogest or Microgynon after conservative surgery.
- Trial name
- NCT02385448
- Testing
- Dienogest, Microgynon
- Where
- Hong Kong
- Volunteers
- 144 people
- Sponsor
- The University of Hong Kong
Polycystic Ovary Syndrome
Effects of Metformin and Oral Hormonal Contraceptive in Adolescents With Polycystic Ovary Syndrome
The polycystic ovary syndrome is the most common endocrinopathy in reproductive age women. The pathophysiology of this syndrome remains unclear, but there are evidences that a decreased in insulin sensitivity may be related in…
- Trial name
- NCT00988078
- Testing
- Metformin
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Adverse Effect of Oral Contraceptives, Initial Encounter
The Effect of Hormonal Contraception on Female
The aim- To evaluate the impact of combined oral contraceptives on women's psychosexual, metabolic, blood coagulation, hormonal and genetic measures.
- Trial name
- HORMCONTRA (NCT01852786)
- Testing
- Contraceptives, Oral, Combined, Controls
- Where
- Lithuania
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Implant Complication, Contraceptive Device; Complications
Improvement of Symptoms After Removal of the Essure® Contraceptive Implant
ESSURE® is an implantable medical device for definitive and irreversible sterilization indicated for adult women of childbearing age. These implants are inserted into the fallopian tubes by hysteroscopy.
- Trial name
- ABLES (NCT06355713)
- Testing
- Magnetic resonance imaging- Positron Emission Tomography (MRI-PET) examination, blood sample, urine collection
- Where
- 10 sites in France
- Volunteers
- 444 people
- Sponsor
- Hospices Civils de Lyon
Menorrhagia
Efficacy of Combined Contraceptive Vaginal Ring(NuvaRing)in Women With Idiopathic Menorrhagia
To compare the efficacy of a combined contraceptive vaginal ring (NuvaRing) and oral Norethisterone Acetate in treatment of Idiopathic heavy menstrual bleeding during fertile age
- Trial name
- NCT01266759
- Testing
- NuvaRing, Norethisterone Acetate tablets - 5mg
- Where
- Egypt
- Volunteers
- 95 people
- Sponsor
- Mansoura University
Contraceptive Device; Complications
Vaginal Misoprostol Before IUD Insertion in Women With Cesarean Scar
Groups of study: 120 candidates for Cu T 380A IUD insertion were enrolled in the study. They were divided into two groups: Group 1: Sixty women received 600 micrograms of misoprostol vaginally as deep as possible six hours before…
- Trial name
- NCT03081442
- Testing
- Misoprostol, Intrauterine contraceptive device IUCD
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Complications; Contraceptive, Female Lactation
Early Versus Standard Postpartum Insertion of the Etonogestrel Contraceptive Implant
A highly effective single rod contraceptive implant is now available for use in the US. Delays in the insertion of the device until later in the postpartum period may negatively impact initiation rates.
- Trial name
- NCT00847587
- Testing
- Etonogestrel contraceptive implant
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Utah
Urinary Tract Infections
Drug Interaction Assessment of GSK3882347 in Healthy Participants Aged 18 to 65 Years
The objective of this study is to determine the magnitude and clinical relevance of a potential drug-drug interaction of GSK3882347 with midazolam (MDZ) in healthy participants.
- Trial name
- NCT05760261
- Testing
- Midazolam, GSK3882347
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Contraceptive Device; Complications, Quality of Life
Quality of Life After Laparoscopic Removal of Essure®
A lot of patients seem to complain after hysteroscopic tubal occlusion by Essure® device with a worce quality of life. Investigators' hypothesis is that Essure® laparoscopic removal may improve quality of life.
- Trial name
- ABLIMCO (NCT03281564)
- Testing
- Quality of life after Essure® removal
- Where
- France
- Volunteers
- 474 people
- Sponsor
- Hospices Civils de Lyon
Menorrhagia
A New Treatment Option for Heavy Menstrual Bleeding
Women with measured menstrual bleeding >80ml per cycle and no contraindications to combined oral contraceptive use will be assigned to an oestradiol/nomegestrol acetate oral contraceptive for 3 cycles during which they will…
- Trial name
- NCT01715025
- Testing
- E2Nomac
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sydney Centre for Reproductive Health Research
Bleeding, Implants
Use of Curcumin to Treat Unfavorable Bleeding Patterns in Contraceptive Implant Users
The investigators plan to study the effects of curcumin, the active ingredient in the spice turmeric, on the irregular bleeding experienced by women who use the contraceptive implant.
- Conditions
- Bleeding, Implants, Breakthrough Bleeding
- Trial name
- NCT04205929
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraceptive Device; Complications
Hysteroscopic Guided Versus Ultrasound Guided Extraction of Retained IUD
The aim of this randomized controlled study is to compare the pain experienced during extraction of retained IUD by office hysteroscopy with the pain experienced during extraction of retained IUD under ultrasound guidance .
- Trial name
- NCT06550544
- Testing
- Office hysteroscopy, Ultrasound guided
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Cairo University
Mechanical Complication of Intrauterine Device
Immediate Post-placental Insertion of IUCD During Cesarean Delivery Versus 6 Week Post-Cesarean Insertion
The aim of current study is to compare the rates of IUCD expulsion and complications in immediate post-placental insertion versus delayed IUCD insertion (6-weeks after cesarean delivery)
- Trial name
- NCT03404622
- Testing
- IUCD
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- ALshaimaa Aboalhassan Ali
Endometriosis
Impact vs. Dienogest: A Combined Oral Contraceptive in the Size of Endometriomas
Project Summary Endometriosis is a disease with a high prevalence that primarily affects women of childbearing age. This condition brings an important physical and emotional burden on sufferers and this is why it requires proper…
- Trial name
- NCT02599077
- Testing
- Dienogest, Levonorgestrel
- Where
- Colombia
- Volunteers
- 50 people
- Sponsor
- Fundación Santa Fe de Bogota